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Condition: Anaphylactic Shock

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Total 7645 results found since Jan 2013.

Exposure to food allergens through inflamed skin promotes intestinal food allergy through the thymic stromal lymphopoietin–basophil axis
Conclusion: Epicutaneous sensitization on a disrupted skin barrier is associated with accumulation of TSLP-elicited basophils, which are necessary and sufficient to promote antigen-induced intestinal food allergy.
Source: Journal of Allergy and Clinical Immunology - February 21, 2014 Category: Allergy & Immunology Authors: Mario Noti, Brian S. Kim, Mark C. Siracusa, Gregory D. Rak, Masato Kubo, Amin E. Moghaddam, Quentin A. Sattentau, Michael R. Comeau, Jonathan M. Spergel, David Artis Tags: Food, drug, insect sting allergy, and anaphylaxis Source Type: research

Multinational experience with hypersensitivity drug reactions in Latin America.
CONCLUSION: Nonsteroidal anti-inflammatory drugs and antibiotics were the drugs used in at least 75% of patients. More than half the reactions were treated in the emergency department, whereas epinephrine was administered in fewer than 25% of patients with anaphylaxis. Dissemination of guidelines for anaphylaxis among primary and emergency department physicians should be encouraged. PMID: 25065979 [PubMed - as supplied by publisher]
Source: Annals of Allergy, Asthma and Immunology - July 24, 2014 Category: Allergy & Immunology Authors: Jares EJ, Sánchez-Borges M, Cardona-Villa R, Ensina LF, Arias-Cruz A, Gómez M, Barayazarra S, Bernstein JA, Serrano CD, Cuello MN, Morfin-Maciel BM, De Falco A, Cherrez-Ojeda I, Latin America Drug Allergy Interest Group Tags: Ann Allergy Asthma Immunol Source Type: research

Sunlight, vitamin D and food allergy
Purpose of review: The role of vitamin D in the development of food allergy is unclear. We summarize recent data on the epidemiologic link between sunlight (UVB) and food allergy, and evidence for and against a specific role for vitamin D status. Recent findings: Since 2007, most epidemiologic studies have supported low sunlight (as measured by season of birth and latitude) as a risk factor for food allergy. Investigators have also looked directly at vitamin D status (as measured by serum 25OHD level) and its potential role. Although conflicting, the vitamin D studies suggest a more complicated association than a linear do...
Source: Current Opinion in Allergy and Clinical Immunology - June 26, 2015 Category: Allergy & Immunology Tags: ANAPHYLAXIS AND INSECT ALLERGY: Edited by Gianenrico Senna and Jeffrey G. Demain Source Type: research

A brief psychological intervention for mothers of children with food allergy can change risk perception and reduce anxiety: outcomes of a randomised controlled trial
ConclusionWe found evidence that a brief psychological intervention which incorporates accurate risk information may impact on anxiety, risk perception and physiological stress response in mothers of children with food allergy.This article is protected by copyright. All rights reserved.
Source: Clinical and Experimental Allergy - July 1, 2017 Category: Allergy & Immunology Authors: Robert J. Boyle, Thisanayagam Umasunthar, Jared G Smith, Heather Hanna, Annabella Procktor, Katherine Phillips, Camila Pinto, Claudia Gore, Helen E. Cox, John O. Warner, Bea Vickers, Matthew Hodes Tags: Original Article ‐Clinical Allergy Source Type: research

Specialist Peri ‐Operative Allergy Clinic Services in the UK 2016: Results from the Royal College of Anaesthetists Sixth National Audit Project (NAP6)
Conclusions and Clinical RelevanceDiagnostic testing is not harmonised, with marked variability in the NMBA panels used to identify safe alternatives. Chlorhexidine and latex are not part of routine testing in many centres.Poor access to services and patient information provision require attention. Harmonisation of diagnostic approach is desirable, particularly with regard to a minimum NMBA panel for identification of safe alternatives.This article is protected by copyright. All rights reserved.
Source: Clinical and Experimental Allergy - August 8, 2017 Category: Allergy & Immunology Authors: William Egner, Tim Cook, Nigel Harper, Tomaz Garcez, Susana Marinho, KL Kong, Shuaib Nasser, Mark Thomas, Amena Warner, John Hitchman, Katharina Floss Tags: Original Article ‐Clinical Allergy Source Type: research

A Retrospective Study of Korean Adults With Food Allergy: Differences in Phenotypes and Causes.
CONCLUSIONS: The major causes of FA in Korean adults were crustacean, fruits, and grains. Interestingly, the clinical manifestations of FA and demographics varied according to type of food allergen. PMID: 28913993 [PubMed]
Source: Allergy, Asthma and Immunology Research - September 17, 2017 Category: Allergy & Immunology Tags: Allergy Asthma Immunol Res Source Type: research

Adenovirus-mediated Gene Therapy for Allergy.
Abstract Allergy poses a heavy health burden in modern society. Other than symptom-relieving medications, the only available treatment approach is allergen-specific immunotherapy, which in spite of offering a potential cure, requires a long treatment duration with multiple doses of allergen administration and carries a risk of anaphylaxis. Gene therapy has shown advantages in experimental studies for treatment of tumors, genetic diseases, chronic infections, and allergy. To date, adenovirus has been the most extensively used gene transfer vector, and offers high efficiency and safety. Here, we review studies of ad...
Source: Iranian Journal of Allergy, Asthma and Immunology - December 1, 2018 Category: Allergy & Immunology Authors: Ma S, Guan J Tags: Iran J Allergy Asthma Immunol Source Type: research

Safe administration of the seasonal trivalent influenza vaccine to children with severe egg allergy.
CONCLUSION: TIV administration is safe even in children with histories of severe egg allergy. Use of 2-step split dosing appears unnecessary because a single dose was well tolerated. PMID: 23176882 [PubMed - in process]
Source: Annals of Allergy, Asthma and Immunology - December 1, 2012 Category: Allergy & Immunology Authors: Greenhawt MJ, Spergel JM, Rank MA, Green TD, Masnoor D, Sharma H, Bird JA, Chang JE, Sinh D, Teich E, Kelso JM, Sanders GM Tags: Ann Allergy Asthma Immunol Source Type: research

Factors that predict the clinical reactivity and tolerance in children with cow's milk allergy.
CONCLUSION: The decision points of sIgE obtained in different age groups may help to determine the likelihood of clinical reactivity more precisely. The results suggest that sIgE levels and STAT6 gene variants may be important determinants to predict longer persistence of CMA. PMID: 23535094 [PubMed - in process]
Source: Annals of Allergy, Asthma and Immunology - April 1, 2013 Category: Allergy & Immunology Authors: Yavuz ST, Buyuktiryaki B, Sahiner UM, Birben E, Tuncer A, Yakarisik S, Karabulut E, Kalayci O, Sackesen C Tags: Ann Allergy Asthma Immunol Source Type: research

Sensitization to Cor a 9 and Cor a 14 is highly specific for a hazelnut allergy with objective symptoms in Dutch children and adults
Conclusion: Sensitization to Cor a 9 and Cor a 14 is highly specific for patients with objective symptoms in DBPCFCs as a marker for a more severe hazelnut allergic phenotype.
Source: Journal of Allergy and Clinical Immunology - April 12, 2013 Category: Allergy & Immunology Authors: Laury J.N. Masthoff, Lars Mattsson, Laurian Zuidmeer-Jongejan, Jonas Lidholm, Kerstin Andersson, Jaap H. Akkerdaas, Serge A. Versteeg, Cristiano Garino, Yolanda Meijer, Petra Kentie, Astrid Versluis, Constance F. den Hartog Jager, Carla A.F.M. Bruijnzeel- Tags: Food, drug, insect sting allergy, and anaphylaxis Source Type: research

Attenuation of food allergy symptoms following treatment with human milk oligosaccharides in a mouse model
ConclusionsOur results suggest that 2’ Fucosylactose and 6’ Sialyllactose reduce the symptoms of food allergy through induction of IL‐10+ T regulatory cells and indirect stabilization of mast cells. Thus, human milk oligosaccharides may have therapeutic potential in allergic disease.This article is protected by copyright. All rights reserved.
Source: Allergy - May 13, 2015 Category: Allergy & Immunology Authors: Lucrecia Castillo ‐Courtade, SangSu Han, Sojeong Lee, Firoz M Mian, Rachael Buck, Paul Forsythe Tags: Original Article: Experimental Allergy and Immunology Source Type: research

Nutritional aspects and diets in food allergy.
Authors: Nowak-Węgrzyn A, Groetch M Abstract Dietary intervention is a crucial component of food allergy management but can negatively impact nutrient intake. A comprehensive nutrition assessment with appropriate intervention is warranted in all children with food allergies to meet nutrient needs and optimize growth. Nutrition assessment may also be indicated in adults with food allergy. Frequently, an elimination diet is absolutely necessary to prevent potentially life-threatening anaphylaxis. Allergen elimination can also improve chronic symptoms, such as atopic dermatitis, when a food is proven to trigger sympt...
Source: Chemical Immunology and Allergy - May 31, 2015 Category: Allergy & Immunology Tags: Chem Immunol Allergy Source Type: research

Anaphylaxis in food allergy.
Authors: Pesek RD, Jones SM Abstract Food allergy is a known trigger of anaphylaxis. Although the awareness of food allergies has improved, food-related allergic reactions and anaphylaxis still commonly occur. The recognition of anaphylaxis, its prompt treatment, and patient education are important for the prevention of future food reactions. Patients and health care providers should also recognize the importance of epinephrine as the primary treatment of anaphylaxis. When food-related anaphylaxis occurs, patients should receive education regarding their food allergies, an epinephrine auto-injector, and follow-up w...
Source: Chemical Immunology and Allergy - May 31, 2015 Category: Allergy & Immunology Tags: Chem Immunol Allergy Source Type: research

One-year survey of paediatric anaphylaxis in an allergy department.
CONCLUSIONS: In our paediatric population, the main triggering agent of anaphylaxis was IgE-mediated food allergy. Epinephrine is underused, as reported by others. Often, children have several episodes before being assessed by an allergist. We stress the importance of systematic notification and improvement of educational programmes in order to achieve a better preventive and therapeutic management of this life-threatening entity. PMID: 26549337 [PubMed - in process]
Source: European Annals of Allergy and Clinical Immunology - November 11, 2015 Category: Allergy & Immunology Tags: Eur Ann Allergy Clin Immunol Source Type: research

Rush immunotherapy for wasp venom allergy seems safe and effective in patients with mastocytosis.
CONCLUSIONS: VIT is safe in cutaneous mastocytosis patients with WA, while caution has to be made in case of systemic mastocytosis. VIT was effective in the patients who were re-stung. PMID: 26549336 [PubMed - in process]
Source: European Annals of Allergy and Clinical Immunology - November 11, 2015 Category: Allergy & Immunology Tags: Eur Ann Allergy Clin Immunol Source Type: research