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Associations of lesion location, structural disconnection, and functional diaschisis with depressive symptoms post stroke
DiscussionBased on our results, and other recent lesion studies, we see growing evidence for a prominent role of right frontostriatal brain circuits in PSDS.
Source: Frontiers in Neurology - May 17, 2023 Category: Neurology Source Type: research

Determinants of post-stroke depression among stroke survivors at University of Gondar Hospital, Northwest Ethiopia: a case-control study
Stroke is one of the most common causes of disability among adults. Post-stroke depression (PSD) is a frequent neuropsychiatric complication in stroke patients. Despite the increasing prevalence of stroke, the...
Source: BMC Neurology - December 1, 2022 Category: Neurology Authors: Ephrem Fantu, Workagegnehu Hailu, Nebiyu Bekele, Tewodros Tsegaye, Melaku Tadesse and Mezgebu Silamsaw Asres Tags: Research Source Type: research

Jidong Restless Legs Syndrome Cohort Study: Objectives, Design, and Baseline Screening
This study will contribute to the scientific evidence on the association between RLS and cardiovascular risks and also provide an unprecedented opportunity for early detection and prevention of CVD.
Source: Frontiers in Neurology - October 13, 2021 Category: Neurology Source Type: research

Stroke Care during the COVID-19 Pandemic: International Expert Panel Review
This study, prepared by a large international panel of stroke experts, assesses the rapidly growing research and personal experience with COVID-19 stroke and offers recommendations for stroke management in this challenging new setting: modifications needed for prehospital emergency rescue and hyperacute care; inpatient intensive or stroke units; posthospitalization rehabilitation; follow-up including at-risk family and community; and multispecialty departmental developments in the allied professions.Summary: The severe acute respiratory syndrome coronavirus 2 uses spike proteins binding to tissue angiotensin-converting enz...
Source: Cerebrovascular Diseases - March 23, 2021 Category: Neurology Source Type: research

Acute and long-term impairments regarding emotional symptoms and quality of life in patients suffering from transient ischemic attack and stroke.
This study follows the hypothesis that TIA patients might exhibit non-physical symptoms affecting individual QoL. Methods: In a prospective single-center observational study, IS patients (n = 73) were compared with TIA patients (n = 24) regarding their neurological deficit, ES and QoL, whereas the latter were evaluated by the Hospital Anxiety and Depression Scale (HADS) and the Short Form 36 Heath Survey (SF-36). Assessments were conducted six times within a one-year follow-up period. Results: Overall, anxiety and depression decreased over time, while anxiety decreased more substantially. TIA patients showed similar le...
Source: Neurological Research - January 24, 2021 Category: Neurology Tags: Neurol Res Source Type: research

Association between obstructive sleep apnea and risk of post-stroke depression: A hospital-based study in ischemic stroke patients
This study aimed to detect the correlation between OSA severity and post-stroke depression (PSD) in ischemic stroke patients.
Source: Journal of Stroke and Cerebrovascular Diseases - May 13, 2020 Category: Neurology Authors: Chuanyou Li, Yuanyue Liu, Pengfei Xu, Qiqi Fan, Pengyu Gong, Caixia Ding, Lei Sheng, Xiaohao Zhang Source Type: research

Risk Factors of Intracerebral Hemorrhage: A Case-Control Study
Background: Hypertension is a well-known risk factor for intracerebral hemorrhage (ICH). On many of the other potential risk factors, such as smoking, diabetes, and alcohol intake, results are conflicting. We assessed risk factors of ICH, taking also into account prior depression and fatigue. Methods: This is a population-based case-control study of 250 primary ICH patients, conducted in Helsinki University Hospital, Finland. The controls (n  = 750) were participants of the FINRISK study, a large Finnish population survey on risk factors of chronic noncommunicable diseases, matched with cases by sex and age.
Source: Journal of Stroke and Cerebrovascular Diseases - January 16, 2020 Category: Neurology Authors: Hanne Sallinen, Arto Pietil ä, Veikko Salomaa, Daniel Strbian Source Type: research

Association Between Fatigue and Cognitive Impairment at 6 Months in Patients With Ischemic Stroke Treated With Acute Revascularization Therapy
Background: Fatigue is a frequent symptom after stroke. We aimed to determine the association between fatigue and cognitive performance in patients with ischemic stroke who received acute revascularization therapy (IV thrombolysis and/or mechanical thrombectomy). Methods: Seventy patients were prospectively included in the stroke unit of the University Hospital of Dijon, France. A follow-up was performed at 6 months with clinical examination, fatigue assessment by the Fatigue Severity Scale (FSS), and a comprehensive neuropsychological evaluation. Patients with fatigue (FSS score> 4) were compared with patients without fa...
Source: Frontiers in Neurology - August 27, 2019 Category: Neurology Source Type: research

More Research Is Needed on Lifestyle Behaviors That Influence Progression of Parkinson's Disease
This article highlights some of these challenges in the design of lifestyle studies in PD, and suggests a more coordinated international effort is required, including ongoing longitudinal observational studies. In combination with pharmaceutical treatments, healthy lifestyle behaviors may slow the progression of PD, empower patients, and reduce disease burden. For optimal care of people with PD, it is important to close this gap in current knowledge and discover whether such associations exist. Introduction Parkinson's disease (PD) is an age-related complex progressive neurodegenerative disorder, with key p...
Source: Frontiers in Neurology - April 29, 2019 Category: Neurology Source Type: research

Factors associated with quality of life early after ischemic stroke: the role of resilience.
DISCUSSION: Resilience was an independent predictor of quality of life beyond anxiety and depression in patients with ischemic stroke. Interventions aimed at improving resilience at acute hospitalization might be a worthwhile addition to improve quality of life early after stroke. PMID: 30957683 [PubMed - as supplied by publisher]
Source: Topics in Stroke Rehabilitation - April 7, 2019 Category: Neurology Authors: Liu Z, Zhou X, Zhang W, Zhou L Tags: Top Stroke Rehabil Source Type: research

Preliminary Screening Recommendations for Patients at Risk of Depression and/or Anxiety more than 1 year Poststroke
Goal: Depression and anxiety are important complications of stroke but are underdiagnosed in community settings. The current study identified which patients were at increased risk of developing either disorder more than1 year poststroke to assist in targeted screening. Methods: Crosssectional survey of 147 adults who had a stroke more than 1 year ago were recruited from stroke advocacy/support groups and an outpatient register. Participants completed the Hospital Anxiety and Depression Scale (HADS) and reported whether they had emotional problems as a stroke inpatient (single item: yes/no).
Source: Journal of Stroke and Cerebrovascular Diseases - March 27, 2019 Category: Neurology Authors: David J. Unsworth, Jane L. Mathias, Diana S. Dorstyn Source Type: research

The Influence of Stroke Location on Cognitive and Mood Impairment. A Voxel-Based Lesion-Symptom Mapping Study
Background and purpose: The role of stroke location as a determinant of mood and cognitive symptoms is still a matter of debate. The aim of this study was to identify the predictive value of ischemic stroke location, on a voxel basis, for mood and cognitive outcome. Materials and methods: A prospective monocentric study including patients with a supratentorial ischemic stroke was conducted. A 3 Tesla brain MRI was performed at baseline. Mood and cognition were assessed using Hospital Anxiety and Depression scale (HAD), apathy inventory (AI), and Montreal Cognitive Assessment scale subscores, performed at 3 months poststroke.
Source: Journal of Stroke and Cerebrovascular Diseases - February 1, 2019 Category: Neurology Authors: Sharmila Sagnier, Fanny Munsch, Antoine Bigourdan, Sabrina Debruxelles, Mathilde Poli, Pauline Renou, St éphane Olindo, François Rouanet, Vincent Dousset, Thomas Tourdias, Igor Sibon Source Type: research

Yawning and cortisol levels in multiple sclerosis: Potential new diagnostic tool
Publication date: July 2018Source: Multiple Sclerosis and Related Disorders, Volume 23Author(s): Simon B.N. Thompson, Alister Coleman, Nicola WilliamsAbstractYawning is a significant behavioural response and, together with cortisol, is potentially a new diagnostic marker of neurological diseases. Evidence of an association between yawning and cortisol was found which supports the Thompson Cortisol Hypothesis and thermoregulation hypotheses, indication that brain cooling occurs when yawning. 117 volunteers aged 18–69 years were randomly allocated to experimentally controlled conditions to provoke yawning. Thirty-three had...
Source: Multiple Sclerosis and Related Disorders - July 10, 2018 Category: Neurology Source Type: research

Yawning and cortisol levels in multiple sclerosis: potential new diagnostic tool
Publication date: Available online 2 May 2018 Source:Multiple Sclerosis and Related Disorders Author(s): Simon B N Thompson, Alister Coleman, Nicola Williams Yawning is a significant behavioural response and, together with cortisol, is potentially a new diagnostic marker of neurological diseases. Evidence of an association between yawning and cortisol was found which supports the Thompson Cortisol Hypothesis and thermoregulation hypotheses, indication that brain cooling occurs when yawning. 117 volunteers aged 18-69 years were randomly allocated to experimentally controlled conditions to provoke yawning. Thirty-three had ...
Source: Multiple Sclerosis and Related Disorders - May 15, 2018 Category: Neurology Source Type: research

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