More Research Is Needed on Lifestyle Behaviors That Influence Progression of Parkinson's Disease

This article highlights some of these challenges in the design of lifestyle studies in PD, and suggests a more coordinated international effort is required, including ongoing longitudinal observational studies. In combination with pharmaceutical treatments, healthy lifestyle behaviors may slow the progression of PD, empower patients, and reduce disease burden. For optimal care of people with PD, it is important to close this gap in current knowledge and discover whether such associations exist. Introduction Parkinson's disease (PD) is an age-related complex progressive neurodegenerative disorder, with key pathological features being the presence of alpha-synuclein-containing Lewy bodies and a loss of dopaminergic neurons in the substantia nigra (1). Years to decades preceding diagnosis, symptoms can include constipation, sleep behavior disorder, hyposmia, and anxiety (2). At diagnosis, hallmark motor symptoms of bradykinesia, as well as either resting tremor or rigidity, are defining (3). The spectrum of motor and non-motor symptoms, and their impact on patient quality of life, suggests a need to individualize treatment. Current treatments primarily act to replace or boost existing dopamine, managing mostly motor symptoms. However, their long-term use leads to side effects, and reduced efficacy (4). Treatment of non-motor symptoms, including fatigue and cognitive impairment, is often secondary though they can have a significant impact on daily living (5, 6). ...
Source: Frontiers in Neurology - Category: Neurology Source Type: research

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I've been interviewed for and hired (onboarding to come) for a low volume rural ED to do a few moonlighting shift in the last few months of residency. I'm excited. I asked my PD what questions to ask the medical director for a low volume ED and the answers were as expected No cath lab, yes STEMI cardiologist on call to guide me with respect to tPA/no tPA and where to ship Tele-neurologist to 'share' my liability and decision making for stroke Radiology reads CT's 24/7, but... Low Volume Rural ED Survival Guide?
Source: Student Doctor Network - Category: Universities & Medical Training Authors: Tags: Emergency Medicine Source Type: forums
Awaken Joy, LLC, Psychiatric Nurse Practitioner, Fairbanks, AK, 99709 | Psychology Today Awaken Joy, LLC, Psychiatric Nurse Practitioner, Fairbanks, AK, 99709, Thank you for your interest. Susana ("Sana") Donofry is a psychiatric nurse practitioner. She prescribes medicine for ADHD and mental health issues like depression, anxiety, and addiction. She accepts most insurance plans... www.psychologytoday.com I was looking at psych profiles in the 20 or so states that allow nurse practitioners to practice independently, it was surprising to s...
Source: Student Doctor Network - Category: Universities & Medical Training Authors: Tags: Psychiatry Source Type: forums
CONCLUSIONS: The interaction and communication between patient and psychiatrist should be improved to capture the need of intervention and to instruct individual supporting measures. PMID: 31952091 [PubMed - as supplied by publisher]
Source: Psychiatrische Praxis - Category: Psychiatry Tags: Psychiatr Prax Source Type: research
CONCLUSION: Psychiatric services might consider different priorities referring to work and life and their impact on coping with depression among men. PMID: 31952090 [PubMed - as supplied by publisher]
Source: Psychiatrische Praxis - Category: Psychiatry Tags: Psychiatr Prax Source Type: research
CONCLUSIONS: The GSDS-26 is a preliminary validated multidimensional scale for better identifying depression in men and may be suitable for routine use after further validation. PMID: 31952089 [PubMed - as supplied by publisher]
Source: Psychiatrische Praxis - Category: Psychiatry Tags: Psychiatr Prax Source Type: research
CONCLUSIONS: Our results stress the relevance of increases in depressive symptoms for upcoming functional decline among the oldest old. Further longitudinal studies are required to replicate our findings. PMID: 31952087 [PubMed - as supplied by publisher]
Source: Psychiatrische Praxis - Category: Psychiatry Tags: Psychiatr Prax Source Type: research
CONCLUSION: Shame needs to be viewed in context of gender roles, status, and their interaction. Future studies should investigate the influence of mental health literacy. PMID: 31952086 [PubMed - as supplied by publisher]
Source: Psychiatrische Praxis - Category: Psychiatry Tags: Psychiatr Prax Source Type: research
CONCLUSIONS: In the population studied mental illness alone was not a sufficient predictor for suicide. Rather, an interaction between mental illness, psychosocial crisis and other factors may explain and predict suicides. Suicide prevention should better address the needs of relatives and family doctors and offer specific low-threshold services. PMID: 31952085 [PubMed - as supplied by publisher]
Source: Psychiatrische Praxis - Category: Psychiatry Tags: Psychiatr Prax Source Type: research
The objective of the study is to describe the prognostic factors that would allow maintaining functionality at 12 months.MethodFrom June 1, 2010 to May 31, 2013, all patients older than 69 years with hip fracture due to bone fragility admitted to the Geriatric Acute Unit of our hospital were included. We define as functional maintenance those patients who have lost between 0 and 15 points in the Barthel Index with respect to the previous to the fracture. Prospective study of bivariate data analysis for related and multivariate prognostic factors for predictive predictors.Results271 patients were included, of them, 146 (54....
Source: Revista Espanola de Cirugia Ortopedica y Traumatologia - Category: Orthopaedics Source Type: research
Publication date: Available online 18 January 2020Source: Journal of Orthopaedic TranslationAuthor(s): Muzhi Li, Yifu Tang, Can Chen, Jiefu Zhou, Cheng Zheng, Huabin Chen, Hongbin Lu, Jin QuAbstractBackgroundMany orthopedic surgical procedures involve reattachment between tendon and bone. Whether bone–tendon healing is better facilitated by tendon fixation on a bone surface or within a tunnel is unknown. The purpose of this study was to comparatively evaluate the effects of bone surface versus bone trough fixation on bone–tendon healing in a rabbit patella–patellar tendon (PPT) injury model.MethodsThe rab...
Source: Journal of Orthopaedic Translation - Category: Orthopaedics Source Type: research
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