Filtered By:
Condition: Obesity
Drug: Insulin

This page shows you your search results in order of relevance. This is page number 9.

Order by Relevance | Date

Total 476 results found since Jan 2013.

Evaluation of the relationship between serum apelin levels and vitamin D and mean platelet volume in diabetic patients.
CONCLUSION: We failed to show an association between vitamin D, apelin and MPV higher volumes of which may have a role in cardiovascular complications related to diabetes by increasing platelet activation. PMID: 25156130 [PubMed - as supplied by publisher]
Source: Annales d'Endocrinologie - August 22, 2014 Category: Endocrinology Authors: Kiskac M, Zorlu M, Cakirca M, Karatoprak C, Kesgin S, Büyükaydın B, Yavuz E, Ardic C, Camli AA, Cikrikcioglu MA Tags: Ann Endocrinol (Paris) Source Type: research

Metabolic syndrome in the prediction of cardiovascular events: the potential additive role of hsCRP and adiponectin
Conclusions MS is an important predictor of cardiovascular events and is most harmful in combination with high plasma hsCRP. The clustering of components is especially harmful.
Source: European Journal of Preventive Cardiology - September 16, 2014 Category: Cardiology Authors: Santaniemi, M., Ukkola, O., Malo, E., Bloigu, R., Kesaniemi, Y. A. Tags: Original scientific papers Source Type: research

What is type 2 diabetes?
Type 2 diabetes mellitus (T2DM) is a common metabolic disorder characterized by chronic hyperglycemia. It is associated with reduced life expectancy owing to a greater risk of heart disease, stroke, peripheral neuropathy, renal disease, blindness and amputation. The best known predictors of increased diabetes risk are elevated fasting plasma glucose, abnormal glucose tolerance test, obesity and evidence of impaired insulin action. However, the mechanisms by which people with impaired fasting glucose and/or abnormal glucose tolerance ‘progress’ to overt T2DM are not completely understood.
Source: Medicine - October 21, 2014 Category: Internal Medicine Authors: Meera Shah, Adrian Vella Tags: Diabetes: basic facts Source Type: research

Resistin in rodents and humans.
Authors: Park HK, Ahima RS Abstract Obesity is characterized by excess accumulation of lipids in adipose tissue and other organs, and chronic inflammation associated with insulin resistance and an increased risk of type 2 diabetes. Obesity, type 2 diabetes, and cardiovascular diseases are major health concerns. Resistin was first discovered as an adipose-secreted hormone (adipokine) linked to obesity and insulin resistance in rodents. Adipocyte-derived resistin is increased in obese rodents and strongly related to insulin resistance. However, in contrast to rodents, resistin is expressed and secreted from macrophag...
Source: Diabetes and Metabolism Journal - November 16, 2014 Category: Endocrinology Tags: Diabetes Metab J Source Type: research

Food Intake Does Not Differ between Obese Women Who Are Metabolically Healthy or Abnormal Nutritional Epidemiology
Conclusions: Healthy obesity was not associated with a healthier diet. Prospective studies on relations of dietary patterns, which may be a better indicator of usual diet, with the phenotype would be beneficial.
Source: Journal of Nutrition - November 19, 2014 Category: Nutrition Authors: Kimokoti, R. W., Judd, S. E., Shikany, J. M., Newby, P. Tags: Nutritional Epidemiology Source Type: research

Macrovascular disease: pathogenesis and risk assessment
Type 2 diabetes mellitus is characterized by obesity and insulin resistance (IR). Macrovascular (cardiovascular) disease (CVD) encompasses myocardial infarction, stroke and peripheral artery disease. It is caused by atherosclerosis, a complex pathological process that is accelerated in people with diabetes and therefore accounts for a higher proportion of total mortality. Risk is modified by established factors including hypertension and dyslipidaemia (which are linked with underlying insulin resistance), and microalbuminuria/renal impairment.
Source: Medicine - November 21, 2014 Category: Internal Medicine Authors: Sandro Vella, John R. Petrie Tags: Macrovascular disease Source Type: research

8 Whole Grains You're Probably Not Eating
By Cynthia Sass, MPH, RD You've probably had oatmeal for breakfast, and if you haven't yet tried quinoa I bet you've heard of it, or have seen it on a menu or social media recipe (it's all over Pinterest!). But there are many other whole grains you may not be familiar with, and incorporating them into your food repertoire is well worth the learning curve. Whole grains are white hot among chefs and nutritionists. They're versatile, satisfying and in addition to providing slow-burning starch (think sustained energy!), vitamins, minerals and antioxidants, whole grains are health protective. Their consumption is tied to a lo...
Source: Healthy Living - The Huffington Post - November 22, 2014 Category: Consumer Health News Source Type: news

Cardiovascular risk factors and events in women with androgen excess
Abstract Androgen excess (AE) was approximated to be present in 7 % of the adult population of women. Polycystic ovary syndrome (PCOS) is the most prevalent among them, followed by idiopathic hirsutism (IH), congenital adrenal hyperplasia (CAH), hyperandrogenic insulin-resistant acanthosis nigricans (HAIRAN) syndrome, and androgen-secreting neoplasms (ASNs). Increased cardiovascular risk was implicated in women with AE. Serum testosterone independently increases risk for cardiovascular disease (CVD), and correlates even with indices of subclinical atherosclerosis in various populations of postmenopausal women. Hy...
Source: Journal of Endocrinological Investigation - November 28, 2014 Category: Endocrinology Source Type: research

The Activated Endocannabinoid System in Atherosclerosis: Driving Force or Protective Mechanism?
Abstract Atherosclerosis and its major acute complications, myocardial infarction and stroke, are the leading causes of death and morbidity worldwide. Despite major advances in cardiovascular intervention and healthcare, improving preventive care and treatment remains a continuous mission for cardiovascular research. Within the last 10 to 15 years, the endocannabinoid system has emerged as an important lipid signaling system involved in many biological processes. Growing evidence suggests that an overactive endocannabinoid-CB1 receptor signaling promotes the development of cardiovascular risk factors such as obesi...
Source: Current Drug Targets - December 1, 2014 Category: Drugs & Pharmacology Authors: Steffens S, Pacher P Tags: Curr Drug Targets Source Type: research

The Insulin-Like Growth Factor I System: Physiological and Pathophysiological Implication in Cardiovascular Diseases Associated with Metabolic Syndrome.
Abstract Metabolic syndrome is a cluster of risk factors including obesity, dyslipidemia, hypertension, and insulin resistance. A number of theories have been speculated for the pathogenesis of metabolic syndrome including impaired glucose and lipid metabolism, lipotoxicity, oxidative stress, interrupted neurohormonal regulation and compromised intracellular Ca(2+) handling. Recent evidence has revealed that adults with severe growth hormone (GH) and insulin-like growth factor I (IGF-1) deficiency such as Laron syndrome display increased risk of stroke and cardiovascular diseases. IGF-1 signaling may regulate cont...
Source: Biochemical Pharmacology - December 22, 2014 Category: Drugs & Pharmacology Authors: Ren J, Anversa P Tags: Biochem Pharmacol Source Type: research

Yes, It's Possible To Be Obese And Healthy (Sort Of)
Not every obese person is unhealthy. More than one-third of American adults with BMIs north of 30 also have a higher risk for developing conditions like type 2 diabetes, heart disease and stroke than the general population. But a small sliver of obese adults defy the odds, maintaining metabolic health despite the excess weight. Scientist don’t yet fully understand the biophysical mechanisms behind “fat but fit” or “healthy obese” -- and there’s even some disagreement about whether or not a healthy obese person can maintain their status over a lifetime. Two recent and unrelated analyses of metabolically healt...
Source: Science - The Huffington Post - January 8, 2015 Category: Science Source Type: news

Promise(s) of using mesenchymal stem cells in reproductive disorders.
Abstract In recent times, infertility among both man and woman has become a major concern affecting about 20 per cent of the population worldwide and has been attributed in part to several aetiological factors such as changes in lifestyle, which includes sedentary life, dietary habits, sleep anomalies, environmental pollution, etc. Assisted reproductive technologies (ART) have come to the rescue of many such couples, but presence of metabolic disorders such as obesity, diabetes with insulin resistance (IR) and its secondary complications (micro- and macro-vascular complications), become confounders to the outcome ...
Source: Indian J Med Res - November 1, 2014 Category: Research Authors: Venkatesan V, Madhira SL Tags: Indian J Med Res Source Type: research

Making one change — getting more fiber — can help with weight loss
Getting to a healthy weight and staying there is an important way to prevent heart disease, diabetes, some cancers, and other serious conditions. Many of us know firsthand just how hard it can be to reach and maintain that healthy weight. And there’s no shortage of ways to try to get there: You can count calories, carbs, or points. You can cut back on fat or sugar. You can try any number of popular diets that forbid certain foods, or focus on just one (the grapefruit diet, anyone?). Any of these approaches might work for you. Or they might not — in large part because they are complicated. A study published in todayR...
Source: New Harvard Health Information - February 17, 2015 Category: Consumer Health News Authors: Nancy Ferrari Tags: Diet and Weight Loss Healthy Eating fiber Source Type: news

7 Ways to Permanently Banish Belly Fat
Sixty-nine percent of Americans adults are overweight, and over 35 percent are obese. Obesity increases your risk for numerous conditions including heart disease, stroke, Type 2 diabetes, high blood pressure, and cancer. Sadly, about 3.4 million adults die each year from being overweight or obese. Globally obesity now kills about the same as tobacco and all wars, terrorism and violence. Nearly all people who are overweight already have "pre-diabetes" and have significant risks of disease and death. They just don't know it. When you begin to put on weight, especially lethal belly fat, your biology shifts out of balance, v...
Source: Healthy Living - The Huffington Post - February 27, 2015 Category: Consumer Health News Source Type: news

Obesity: single house for many evils.
Authors: Kumar A, Nayak BP, Kumar A Abstract World Health Organization (WHO) considers obesity as one of the fastest growing metabolic disorders other than diabetes. It is a complex interplay of lifestyle and associated genes. Obesity has been considered as a disease with multiple targets and very often compared in this sense with its sibling disease type 2 diabetes. The disease is pathology of the adipocytes and develops as a result of hypertrophy and hyperplasia of these cells, former being the major concern but its effects could be seen on various organs in the form of cardio-vascular disease, stroke, cancer, di...
Source: Minerva Endocrinologica - June 4, 2015 Category: Endocrinology Tags: Minerva Endocrinol Source Type: research