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Neuroimaging Findings in Cryptogenic Stroke Patients With and Without Patent Foramen Ovale Clinical Sciences
Conclusions— This is the largest study to report the radiological characteristics of patients with cryptogenic stroke and known PFO status. Strokes that were large, radiologically apparent, superficially located, or unassociated with prior radiological infarcts were more likely to be PFO-associated than were unapparent, smaller, or deep strokes, and those accompanied by chronic infarcts. There was no association between PFO and multiple acute strokes nor between specific echocardiographic PFO features with neuroimaging findings.
Source: Stroke - February 25, 2013 Category: Neurology Authors: Thaler, D. E., Ruthazer, R., Di Angelantonio, E., Di Tullio, M. R., Donovan, J. S., Elkind, M. S. V., Griffith, J., Homma, S., Jaigobin, C., Mas, J.-L., Mattle, H. P., Michel, P., Mono, M.-L., Nedeltchev, K., Papetti, F., Serena, J., Weimar, C., Kent, D. Tags: Cerebrovascular disease/stroke, Pediatric and congenital heart disease, including cardiovascular surgery, Computerized tomography and Magnetic Resonance Imaging, Risk Factors for Stroke Clinical Sciences Source Type: research

Coronary Artery Calcification, Intima-Media Thickness, and Ankle-Brachial Index Are Complementary Stroke Predictors Clinical Sciences
Conclusions— CAC, CIMT, and ABI provide complementary information about stroke risk. ABI, which is distinctive in a small subpopulation, had the highest and CIMT, which is distributed across a larger range of values, had the lowest predictive value.
Source: Stroke - August 25, 2014 Category: Neurology Authors: Gronewold, J., Bauer, M., Lehmann, N., Mahabadi, A. A., Kalsch, H., Weimar, C., Berger, K., Moebus, S., Jockel, K.-H., Erbel, R., Hermann, D. M., on behalf of the Heinz Nixdorf Recall Study Investigative Group Tags: Imaging, Computerized tomography and Magnetic Resonance Imaging, Doppler ultrasound, Transcranial Doppler etc., Risk Factors for Stroke Clinical Sciences Source Type: research

Carotid Atherosclerotic Plaque Characteristics on Magnetic Resonance Imaging Relate With History of Stroke and Coronary Heart Disease Clinical Sciences
Conclusions— Whereas carotid plaque thickness and stenosis are associated with the history of ischemic stroke and CHD, carotid intraplaque hemorrhage is associated with ischemic stroke, but not with CHD, providing novel insights into the pathogenesis of cardiovascular events.
Source: Stroke - May 22, 2016 Category: Neurology Authors: Selwaness, M., Bos, D., van den Bouwhuijsen, Q., Portegies, M. L. P., Ikram, M. A., Hofman, A., Franco, O. H., van der Lugt, A., Wentzel, J. J., Vernooij, M. W. Tags: Cardiovascular Disease, Epidemiology, Magnetic Resonance Imaging (MRI), Ischemic Stroke, Atherosclerosis Clinical Sciences Source Type: research

Clopidogrel Use Is Associated With an Increased Prevalence of Cerebral Microbleeds in a Stroke-Free Population: The Rotterdam Study Stroke
Conclusions In stroke-free individuals, clopidogrel use was associated with a higher prevalence and higher number of CMBs. Whether this association is causal requires confirmation in prospective studies, especially given the small number of participants taking clopidogrel and the possibility of residual confounding in this study.
Source: JAHA:Journal of the American Heart Association - September 26, 2013 Category: Cardiology Authors: Darweesh, S. K. L., Leening, M. J. G., Akoudad, S., Loth, D. W., Hofman, A., Arfan Ikram, M., Vernooij, M. W., Stricker, B. H. Tags: Stroke Source Type: research

Pathogenesis and Risk Factors for Cerebral Infarct After Surgical Aortic Valve Replacement Brief Reports
Conclusions— The principal mechanism of acute cerebral infarction after aortic valve replacement is embolism. There are distinct factors associated with watershed and embolic infarct, some of which may be modifiable.
Source: Stroke - July 24, 2016 Category: Neurology Authors: Massaro, A., Messe, S. R., Acker, M. A., Kasner, S. E., Torres, J., Fanning, M., Giovannetti, T., Ratcliffe, S. J., Bilello, M., Szeto, W. Y., Bavaria, J. E., Mohler, E. R., Floyd, T. F., for the Determining Neurologic Outcomes From Valve Operations (DeNO Tags: Valvular Heart Disease, Magnetic Resonance Imaging (MRI), Cardiovascular Surgery, Cerebrovascular Disease/Stroke, Ischemic Stroke Brief Reports Source Type: research

Stroke Dysbiosis Index (SDI) in Gut Microbiome Are Associated With Brain Injury and Prognosis of Stroke
Conclusions: We developed an index to measure gut microbiota dysbiosis in stroke patients; this index was significantly correlated with patients' outcome and was causally related to outcome in a mouse model of stroke. Our model facilitates the potential clinical application of gut microbiota data in stroke and adds quantitative evidence linking the gut microbiota to stroke. Introduction Ischemic stroke imposes a heavy burden on society, with 24.9 million cases worldwide (1). Although intravenous thrombolysis and endovascular treatment greatly improve some patients' prognosis, the prognosis for most pa...
Source: Frontiers in Neurology - April 23, 2019 Category: Neurology Source Type: research

Shengui Sansheng San Ameliorates Cerebral Energy Deficiency via Citrate Cycle After Ischemic Stroke
Conclusion In summary, SSS extraction significantly ameliorates cerebral energy metabolism via boosting citrate cycle, which mainly embodies the enhancements of blood glucose concentration, glucose and lactate transportation and glucose utilization, as well as the regulations of relative enzymes activities in citrate cycle. These ameliorations ultimately resulted in numerous ATP yield after stroke, which improved neurological function and infarcted volume. Collectively, it suggests that SSS extraction has exerted advantageous effect in the treatment of cerebral ischemia. Ethics Statement All animal operations were accor...
Source: Frontiers in Pharmacology - April 22, 2019 Category: Drugs & Pharmacology Source Type: research

Cerebral Microbleeds Determine Long-Term Mortality in Acute Ischemic Stroke Patients with Lacunar Subtype (P1.015)
CONCLUSIONS: The presence, multiplicity and distribution of CMBs were associated with increased mortality in lacunar stroke patients. The detection and evaluation of CMBs is of value in predicting long-term prognosis in lacunar stroke patients. Study Supported: None.Disclosure: Dr. Song has nothing to disclose. Dr. Younkyung has nothing to disclose. Dr. Youn has nothing to disclose. Dr. Heo has nothing to disclose. Dr. Kim has nothing to disclose.
Source: Neurology - April 8, 2015 Category: Neurology Authors: Song, T.-J., Younkyung, C., Youn, M., Heo, J. H., Kim, Y. J. Tags: Cerebrovascular Disease and Interventional Neurology I ePosters Source Type: research

Cerebral Microbleeds Do Not Predict Hemorrhagic Transformation in Acute Ischemic Stroke Patients with Atrial Fibrillation and/or Rheumatic Heart Disease.
Conclusion The present study suggests that CMBs do not predict the presence of hemorrhagic transformation in acute ischemic stroke patients with AF and/or RHD. The results were not affected by anticoagulant or antiplatelet agents used in acute stage of ischemic stroke. PMID: 28294063 [PubMed - as supplied by publisher]
Source: Current Neurovascular Research - March 12, 2017 Category: Neurology Authors: Liu J, Wang D, Li J, Lin J, Xiong Y, Liu B, Wei C, Wu B, Ma Z, Zhang S, Liu M Tags: Curr Neurovasc Res Source Type: research

Brain Infarction MRI Pattern in Stroke Patients with Intracardiac Thrombus
Conclusions: ICT-related stroke is associated with acute SCCI presence on MRI.Clinical Trial Registration-URL: http://www.clinicaltrials.gov. Unique identifier: NCT04456309.Cerebrovasc Dis
Source: Cerebrovascular Diseases - June 17, 2021 Category: Neurology Source Type: research

Predictors of Poor Outcome in Patients with Minor Ischemic Stroke by Using Magnetic Resonance Imaging
This study indicated that age, heart disease, motor distur bance of limb, ataxia, early neurological deterioration, diameter of infarction, size of non-responsible vessels, and large-artery atherosclerosis can be used to assess the prognosis of patients with minor ischemic stroke.
Source: Journal of Molecular Neuroscience - July 19, 2019 Category: Neuroscience Source Type: research

Left ventricular geometry and white matter lesions in ischemic stroke patients.
Authors: Butenaerts D, Chrzanowska-Wasko J, Slowik A, Dziedzic T Abstract Abnormal left ventricular (LV) geometry is associated with extracardiac organ damage in patients with hypertension. The aim of this study was to determine the relationship between LV geometry and white matter lesions (WMLs) in ischemic stroke patients. We retrospectively analyzed data from 155 patients (median age 62; 49.8% male) with mild ischemic stroke (median National Institutes of Health Stroke Scale score 4) who underwent brain magnetic resonance imaging and echocardiography. Patients were categorized into four groups: normal LV geometr...
Source: Blood Pressure - February 14, 2016 Category: Hematology Tags: Blood Press Source Type: research

Global Cortical Atrophy Is Associated with an Unfavorable Outcome in Stroke Patients on Oral Anticoagulation
Conclusion: GCA was associated with our composite outcome also after adjusting for other cSVD markers (i.e., CMB, WMH) and age, indicating that GCA may potentially serve as a prognostic marker for stroke patients with atrial fibrillation on oral anticoagulation.Cerebrovasc Dis
Source: Cerebrovascular Diseases - December 13, 2022 Category: Neurology Source Type: research

Quantification of Chronic Functional Mitral Regurgitation by Automated 3-Dimensional Peak and Integrated Proximal Isovelocity Surface Area and Stroke Volume Techniques Using Real-Time 3-Dimensional Volume Color Doppler Echocardiography: In Vitro and Clinical Validation Original Articles
Conclusions— Automated real-time 3D volume color flow Doppler based 3D PISA is more accurate than the 2D PISA method to quantify MR. In patients with functional MR, the 3D RVol by integrated PISA is more accurate than a peak PISA technique. Automated 3D stroke volume measurement can also be used as an adjunctive method to quantify MR severity.
Source: Circulation: Cardiovascular Imaging - January 15, 2013 Category: Radiology Authors: Thavendiranathan, P., Liu, S., Datta, S., Rajagopalan, S., Ryan, T., Igo, S. R., Jackson, M. S., Little, S. H., De Michelis, N., Vannan, M. A. Tags: Valvular heart disease, Echocardiography Original Articles Source Type: research

Association of Cerebral Microbleeds with Higher Morbidity and Mortality in Ischemic Stroke? (P1.044)
CONCLUSIONS: Microbleed in ischemic stroke on magnetic resonance imaging scan is associated with higher morbidity and mortality especially in older patients with uncontrolled hypertension and anticoagulant therapy.Disclosure: Dr. Ahad has nothing to disclose. Dr. Ahmed has nothing to disclose. Dr. Lee has nothing to disclose. Dr. Duggal has nothing to disclose.
Source: Neurology - April 8, 2015 Category: Neurology Authors: Ahad, R., Ahmed, I., Lee, G., Duggal, N. Tags: Cerebrovascular Disease and Interventional Neurology: The Spectrum of Small Vessel Cerebrovascular Disease Source Type: research

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