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Total 532 results found since Jan 2013.

Telomere Length, Long-Term Black Carbon Exposure, and Cognitive Function in a Cohort of Older Men: The VA Normative Aging Study
Conclusions: TL and CRP levels may help predict the impact of BC exposure on cognitive function in older men. Citation: Colicino E, Wilson A, Frisardi MC, Prada D, Power MC, Hoxha M, Dioni L, Spiro A III, Vokonas PS, Weisskopf MG, Schwartz JD, Baccarelli AA. 2017. Telomere length, long-term black carbon exposure, and cognitive function in a cohort of older men: the VA Normative Aging Study. Environ Health Perspect 125:76–81; http://dx.doi.org/10.1289/EHP241 Address correspondence to E. Colicino, Department of Environmental Health, Harvard T.H. Chan School of Public Health, 665 Huntington Ave., Building 1, Room G03, Bos...
Source: EHP Research - January 2, 2017 Category: Environmental Health Authors: Web Admin Tags: Research Articles January 2017 Source Type: research

Long-term hormone therapy for perimenopausal and postmenopausal women.
CONCLUSIONS: Women with intolerable menopausal symptoms may wish to weigh the benefits of symptom relief against the small absolute risk of harm arising from short-term use of low-dose HT, provided they do not have specific contraindications. HT may be unsuitable for some women, including those at increased risk of cardiovascular disease, increased risk of thromboembolic disease (such as those with obesity or a history of venous thrombosis) or increased risk of some types of cancer (such as breast cancer, in women with a uterus). The risk of endometrial cancer among women with a uterus taking oestrogen-only HT is well docu...
Source: Cochrane Database of Systematic Reviews - January 16, 2017 Category: Journals (General) Authors: Marjoribanks J, Farquhar C, Roberts H, Lethaby A, Lee J Tags: Cochrane Database Syst Rev Source Type: research

Health burden attributable to ambient PM2.5 in China.
Abstract In China, over 1.3 billion people have high health risks associated with exposure to ambient fine particulate matter (PM2.5) that exceeds the World Health Organization (WHO) Air Quality Guidelines (AQG). The PM2.5 mass concentrations from 1382 national air quality monitoring stations in 367 cities, between January 2014 and December 2016, were analyzed to estimate the health burden attributable to ambient PM2.5 across China. The integrated exposure-response model was applied to estimate the relative risks of disease-specific mortality. Disease-specific mortality baselines in province-level administrative u...
Source: Environmental Pollution - February 2, 2017 Category: Environmental Health Authors: Song C, He J, Wu L, Jin T, Chen X, Li R, Ren P, Zhang L, Mao H Tags: Environ Pollut Source Type: research

Morbidity and Causes of Death in Patients with Cutaneous T-cell Lymphoma in Finland.
Abstract Cutaneous T-cell lymphomas (CTCL), especially mycosis fungoides, can be considered as a state of longstanding low-grade systemic inflammation. Many studies have focused on secondary cancers with CTCL, but information about comorbidities is limited. A total of 144 patients with CTCL at Helsinki University Central Hospital during 2005 to 2015 were studied to determine associated comorbidities and causes of death in this cohort. Compared with an age-standardized control population, the prevalence of type 2 diabetes mellitus was increased among patients with CTCL with no link to obesity. Patients with CTCL ha...
Source: Acta Dermato-Venereologica - February 7, 2017 Category: Dermatology Authors: Väkevä L, Lipsanen T, Sintonen H, Ranki A Tags: Acta Derm Venereol Source Type: research

Pharmacogenomics and tailored polypharmacy: an 80-year-old lady with rosuvastatin-associated rhabdomyolysis and maprotiline-related Ogilvie's syndrome 
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We present a unique case of synchronous rhabdomyolysis and Ogilvie's syndrome in an 80-year-old lung cancer survivor following a recent ischemic stroke for which she was prescribed clopidogrel and rosuvastatin for secondary prevention, and maprotiline for post-stroke, new-onset insomnia and anxiety. The ADRs resolved on removal of the offending agents and initiation of conservative treatment. Retrospective pharmacogenetic testing of the patient's drug-metabolizing enzymes and transporters was performed to guide further management and prevent future potential drug interactions and ADRs. What is novel and conclusions: This i...
Source: International Journal of Clinical Pharmacology and Therapeutics - March 5, 2017 Category: Drugs & Pharmacology Tags: Int J Clin Pharmacol Ther Source Type: research

Trends in educational inequalities in premature mortality in Belgium between the 1990s and the 2000s: the contribution of specific causes of deaths
Conclusion Absolute inequalities decreased in men while increasing in women; relative inequalities increased in both sexes. The PAFs decomposition revealed that targeting mortality inequalities from lung cancer, IHD, COPD in both sexes, suicide in men and stroke in women would have the largest impact at population level.
Source: Journal of Epidemiology and Community Health - March 6, 2017 Category: Epidemiology Authors: Renard, F., Gadeyne, S., Devleesschauwer, B., Tafforeau, J., Deboosere, P. Tags: Epidemiologic studies, Mortality and morbidity, Suicide (psychiatry), Health service research, Suicide (public health) Research reports Source Type: research

National and sub-national age-sex specific and cause-specific mortality and disability-adjusted life years (DALYs) attributable to household air pollution from solid cookfuel use (HAP) in Iran, 1990-2013.
Abstract National and sub-national mortality, years of life lost due to premature mortality (YLLs), years lived with disability (YLDs) and disability-adjusted life years (DALYs) for household air pollution from solid cookfuel use (HAP) in Iran, 1990-2013 were estimated based on the Global Burden of Disease Study 2013 (GBD 2013). The burden of disease attributable to HAP was quantified by the comparative risk assessment method using four inputs: (1) exposure to HAP, (2) the theoretical minimum risk exposure level (TMREL), (3) exposure-response relationships of related causes (4) disease burden of related causes. Al...
Source: Environmental Research - March 21, 2017 Category: Environmental Health Authors: Abtahi M, Koolivand A, Dobaradaran S, Yaghmaeian K, Mohseni-Bandpei A, Khaloo SS, Jorfi S, Saeedi R Tags: Environ Res Source Type: research

IJERPH, Vol. 14, Pages 1321: Spatiotemporal Changes in Fine Particulate Matter Pollution and the Associated Mortality Burden in China between 2015 and 2016
ingyun Du Lu Ma In recent years, research on the spatiotemporal distribution and health effects of fine particulate matter (PM2.5) has been conducted in China. However, the limitations of different research scopes and methods have led to low comparability between regions regarding the mortality burden of PM2.5. A kriging model was used to simulate the distribution of PM2.5 in 2015 and 2016. Relative risk (RR) at a specified PM2.5 exposure concentration was estimated with an integrated exposure–response (IER) model for different causes of mortality: lung cancer (LC), ischaemic heart disease (IHD), cerebrovascular di...
Source: International Journal of Environmental Research and Public Health - October 30, 2017 Category: Environmental Health Authors: Luwei Feng Bo Ye Huan Feng Fu Ren Shichun Huang Xiaotong Zhang Yunquan Zhang Qingyun Du Lu Ma Tags: Article Source Type: research

The current and potential health benefits of the National Health Service Health Check cardiovascular disease prevention programme in England: A microsimulation study
ConclusionsOur model indicates that the current NHS Health Check programme is contributing to improvements in health and reducing health inequalities. Feasible changes in the organisation of the programme could result in more than a 3-fold increase in health benefits.
Source: PLoS Medicine - March 6, 2018 Category: Internal Medicine Authors: Oliver T. Mytton Source Type: research

Preventable Heart Problems Killed 415,000 People in 2016. Here ’s How to Keep Your Heart Healthy
Heart problems that were “largely preventable” killed around 415,000 Americans in 2016, new data from the Centers for Disease Control and Prevention (CDC) says, highlighting the importance of proactive interventions. Under its new Million Hearts campaign, which aims to prevent a million heart attacks and strokes by 2022, the CDC looked at 2016 data and identified approximately 2.2 million hospitalizations and 415,000 deaths caused by heart attacks, strokes, heart failure and related conditions that likely could have been avoided. The total number of deaths related to heart issues is even higher — in 2015,...
Source: TIME: Health - September 6, 2018 Category: Consumer Health News Authors: Jamie Ducharme Tags: Uncategorized healthytime Heart Disease onetime Source Type: news

IJERPH, Vol. 15, Pages 2244: Tobacco Health Risk Awareness among Socially Disadvantaged People —A Crucial Tool for Smoking Cessation
IJERPH, Vol. 15, Pages 2244: Tobacco Health Risk Awareness among Socially Disadvantaged People—A Crucial Tool for Smoking Cessation International Journal of Environmental Research and Public Health doi: 10.3390/ijerph15102244 Authors: Marek Milcarz Kinga Polanska Leokadia Bak-Romaniszyn Dorota Kaleta The goal of this cross-sectional survey was to assess the level of knowledge on harmful effects of environmental tobacco smoke (ETS) exposure and active smoking among socially-disadvantaged people in Poland. The study was conducted among 1817 respondents aged 18–59 years, who used aid services fro...
Source: International Journal of Environmental Research and Public Health - October 13, 2018 Category: Environmental Health Authors: Marek Milcarz Kinga Polanska Leokadia Bak-Romaniszyn Dorota Kaleta Tags: Article Source Type: research

Korean JLK Inspection launches AI-powered imaging diag system
Korean JLK Inspection said yesterday that it launched its AIHub artificial intelligence-powered medical image diagnostics platform. The newly launched AIHub system is designed to analyze images from a number of different imaging modalities, including magnetic resonance imaging, computed tomography, X-ray and mammography, the Seoul-based company said. JLK Inspection claims the system can detect and monitor for more than 30 medical conditions in 14 regions of the body. The company added that the system is focused on brain diseases and conditions including ischemic stroke, hemorrhagic stroke, brain aneurysm and Alzheimer̵...
Source: Mass Device - December 27, 2018 Category: Medical Devices Authors: Fink Densford Tags: Diagnostics Imaging Software / IT jlkinspection Source Type: news

Health risk associated with potential source regions of PM 2.5 in Indian cities
AbstractThis paper estimates the regional contribution of high PM2.5 concentration and associated mortality using HYSPLIT back trajectory analysis in eight Indian cities during 2015 –2016. Health risk and mortality estimation were carried out using the Integrated Exposure Response function (IER) which was verified using our previous time series study in Delhi. Risk estimates from IER were observed to be slightly over-predicted (2.14%) when compared to health risk from time se ries study in Delhi. Health risk in the eight cities across the four seasons indicated higher chronic obstructive pulmonary disease (COPD), lung ca...
Source: Air Quality, Atmosphere and Health - January 10, 2019 Category: Environmental Health Source Type: research

Synchronous cerebral arteriovenous malformation and lung adenocarcinoma carcinoma brain metastases: A case study and literature review.
CONCLUSION: This case represents a previously undocumented confluence of cranial AVM that initially masked a non-small cell lung cancer brain metastasis. PMID: 30638546 [PubMed - as supplied by publisher]
Source: Neurochirurgie - January 15, 2019 Category: Neurosurgery Tags: Neurochirurgie Source Type: research

Association study between genetic polymorphisms in folate metabolism and gastric cancer susceptibility in Chinese Han population: A case –control study
ConclusionThis study suggested that MTR andMTHFRpolymorphisms may contribute to increase the risk of GC.
Source: Molecular Genetics & Genomic Medicine - March 17, 2019 Category: Genetics & Stem Cells Authors: Lusha Wei, Fanglin Niu, Jiamin Wu, Fulin Chen, Hua Yang, Jing Li, Tianbo Jin, Yifei Wu Tags: ORIGINAL ARTICLE Source Type: research