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FDA Approves Two New Indications for XARELTO ® (rivaroxaban) to Help Prevent and Treat Blood Clots in Pediatric Patients
RARITAN, NJ, Dec. 20, 2021 – The Janssen Pharmaceutical Companies of Johnson & Johnson announced today that the U.S. Food and Drug Administration (FDA) has approved two pediatric indications for XARELTO® (rivaroxaban): the treatment of venous thromboembolism (VTE, or blood clots) and reduction in the risk of recurrent VTE in patients from birth to less than 18 years after at least five days of initial parenteral (injected or intravenous) anticoagulant treatment; and thromboprophylaxis (prevention of blood clots and blood-clot related events) in children aged two years and older with congenital heart disease who have...
Source: Johnson and Johnson - December 21, 2021 Category: Pharmaceuticals Tags: Innovation Source Type: news

Environmental Pollution: An Under-recognized Threat to Children’s Health, Especially in Low- and Middle-Income Countries
Conclusions Patterns of disease are changing rapidly in LMICs. Pollution-related chronic diseases are becoming more common. This shift presents a particular problem for children, who are proportionately more heavily exposed than are adults to environmental pollutants and for whom these exposures are especially dangerous. Better quantification of environmental exposures and stepped-up efforts to understand how to prevent exposures that cause disease are needed in LMICs and around the globe. To confront the global problem of disease caused by pollution, improved programs of public health monitoring and environmental protecti...
Source: EHP Research - March 1, 2016 Category: Environmental Health Authors: Web Admin Tags: Brief Communication March 2016 Source Type: research

Women ’s Health Policies Should Focus on NCDs
Professor Robyn Norton, co-founder and Principal Director of the George Institute for Global Health. Credit: Neena Bhandari/IPSBy Neena BhandariSYDNEY, Apr 11 2017 (IPS)Science and medicine were not subjects of dinnertime conversations in the Norton household in Christchurch, New Zealand, but Professor Robyn Norton grew up observing her parents’ commitment to equity and social justice in improving people’s lives. It left an indelible impression on her young mind.Her high school years coincided with the women’s movement reaching its peak. She got drawn into thinking about addressing women’s health issues and moved t...
Source: IPS Inter Press Service - Health - April 11, 2017 Category: Global & Universal Authors: Neena Bhandari Tags: Asia-Pacific Featured Global Headlines Health Poverty & SDGs Women's Health Non-communicable Diseases (NCDs) Source Type: news

Cardiovascular Programming During and After Diabetic Pregnancy: Role of Placental Dysfunction and IUGR
This study demonstrated that the incidence of ischemic heart disease and death were three times higher among men with low birth weight compared to men with high birth weight (5). Epidemiological investigations of adults born at the time of the Dutch famine between 1944 and 1945 revealed an association between maternal starvation and a low infant birth weight with a high incidence of hypertension and coronary heart disease in these adults (23). Furthermore, Painter et al. reported the incidence of early onset coronary heart disease among persons conceived during the Dutch famine (24). In that regard, Barker's findin...
Source: Frontiers in Endocrinology - April 8, 2019 Category: Endocrinology Source Type: research

Teen drinking linked to raised breast cancer risk
Conclusion Alcohol consumption is already recognised as a risk factor for breast cancer. And this large, well-conducted study seems to confirm that young women between their first period and first pregnancy are particularly susceptible.  One limitation of the study is that the women were asked to recall their drinking habits when they were far younger, which could mean the results are less reliable. Also, other factors called confounders might have affected women’s risk of breast cancer, although researchers did adjust their findings for a range of other risk factors. As the authors point out, it is crucial that youn...
Source: NHS News Feed - August 29, 2013 Category: Consumer Health News Tags: Cancer Lifestyle/exercise Source Type: news

Children of the 90s more likely to be overweight or obese
Conclusion The study shows how, while the whole population of England has become heavier over the past 70 years, different generations have been affected in different ways. People born in 1946 were, on average, normal weight until their 40s, but this group has since seen their weight rise and they are now, on average, overweight. By the time they reached 60, 75% of men and 66% of women from this group were overweight or obese. People born in 1946 from the heaviest cohorts, who were already overweight in early adulthood, are now likely to be obese or very obese. For people born since 1946, the chance of being overweight a...
Source: NHS News Feed - May 20, 2015 Category: Consumer Health News Tags: Obesity Pregnancy/child Source Type: news

The Quality Of Health Care You Receive Likely Depends On Your Skin Color
Unequal health care continues to be a serious problem for black Americans. More than a decade after the Institute of Medicine issued a landmark report showing that minority patients were less likely to receive the same quality health care as white patients, racial and ethnic disparities continue to plague the U.S. health care system. That report, which was published in 2002, indicated that even when both groups had similar insurance or the same ability to pay for care, black patients received inferior treatment to white patients. This still hold true, according to our investigation into dozens of studies about black health...
Source: Healthy Living - The Huffington Post - June 29, 2015 Category: Consumer Health News Source Type: news

An Overview of Quadrivalent Human Papillomavirus Vaccine Safety: 2006 to 2015
Conclusions: These results, along with the safety data from the prelicensure clinical trials, confirm that the HPV4 vaccine has a favorable safety profile. Key policy, medical and regulatory organizations around the world have independently reviewed these data and continue to recommend routine HPV vaccination.
Source: The Pediatric Infectious Disease Journal - August 14, 2015 Category: Infectious Diseases Tags: Vaccine Reports Source Type: research

Leading Health Mistakes Women Make In Their 30s
Credit For many women, turning 30 marks the real beginning of adulthood. You're established in a career, and maybe in a relationship. You might be thinking about starting a family. You feel pretty good about yourself, and all the health indiscretions of your 20s (remember those all-night parties and how you still managed to make it into work the next day?) haven't taken much of a health toll. But let's face it, ages 30 to 39 are prime time. All in all, the 30s are a very positive time for health, but it's also the time you have to start developing excellent habits as an investment in the future, says Dr. Debra DeJoseph,...
Source: Healthy Living - The Huffington Post - August 17, 2016 Category: Consumer Health News Source Type: news

UCLA helps many to live long and prosper
In Westwood, more than 100 faculty experts from 25 departments have embarked on anall-encompassing push to cut the health and economic impacts of depression in half by the year 2050. The mammoth undertaking will rely on platforms developed by the new Institute for Precision Health, which will harness the power of big data and genomics to move toward individually tailored treatments and health-promotion strategies.On the same 419 acres of land, researchers across the spectrum, from the laboratory bench to the patient bedside, are ushering in a potentially game-changing approach to turning the body ’s immune defenses again...
Source: UCLA Newsroom: Health Sciences - November 9, 2017 Category: Universities & Medical Training Source Type: news

Sex Difference of Radiation Response in Occupational and Accidental Exposure
Conclusion and Outlook This review summarizes the data from major human studies on the health risks of radiation exposure and shows that sex can potentially influence the prolonged response to radiation exposure (Figure 1 and Tables 1, 2). These data suggest that long-term radiosensitivity in females is higher than that in males who receive a comparable dose of radiation. Our analysis of the literature agrees with the conclusions of the recent report on the Biological effects of ionizing radiation (BEIR VII) published in 2006 by the National Academy of Sciences (NAS), United States (National Research Council, 2006). The B...
Source: Frontiers in Genetics - May 2, 2019 Category: Genetics & Stem Cells Source Type: research

Marijuana Use for Women: To Prescribe or Not to Prescribe.
Conclusions: Benefits and risks for both the patient and the offspring especially in the long term regarding marijuana use should be carefully weighed for each specific case. Standardized dosing and duration of treatment need to be determined. Recommendations should be made by physicians with expert training and after careful patient evaluation for fully informed patients, whose preference should be respected. Legislations should encourage more active basic, translational, and clinical studies. PMID: 32627638 [PubMed - as supplied by publisher]
Source: Substance Use and Misuse - July 8, 2020 Category: Addiction Tags: Subst Use Misuse Source Type: research

New Analyses Suggest Favorable Results for STELARA ® (ustekinumab) When Used as a First-Line Therapy for Bio-Naïve Patients with Moderately to Severely Active Crohn’s Disease and Ulcerative Colitis
SPRING HOUSE, PENNSYLVANIA, October 25, 2021 – The Janssen Pharmaceutical Companies of Johnson & Johnson today announced data from two new analyses of STELARA® (ustekinumab) for the treatment of adults with moderately to severely active Crohn’s disease (CD) and ulcerative colitis (UC).1,2 In a modelled analysisa focused on treatment sequencing using data from randomized controlled trials, network meta-analysis and literature, results showed patient time spent in clinical remission or response was highest when STELARA was used as a first-line advanced therapy for bio-naïve patients with moderately to severely acti...
Source: Johnson and Johnson - October 25, 2021 Category: Pharmaceuticals Tags: Innovation Source Type: news