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Total 121623 results found since Jan 2013.

Survival analysis and factors affecting survival in patients who presented to the medical oncology unit with non-small cell lung cancer.
CONCLUSIONS: In this study, gender, stage, performance status, presence of liver or bone metastases and treatment had an effect on overall survival. PMID: 32512671 [PubMed - as supplied by publisher]
Source: Turkish Journal of Medical Sciences - June 10, 2020 Category: General Medicine Tags: Turk J Med Sci Source Type: research

Fine-tuned continuous renal replacement therapy with calcium-free dialysate to manage severe hypercalcemia refractory to medical and intermittent hemodialysis
AbstractMalignancy-related hypercalcemia is a leading cause of hypercalcemia among hospitalized patients that carries poor prognosis. Parathyroid carcinoma is a rare form of primary hyperparathyroidism that may be associated with PTH dependent hypercalcemia. Severe hypercalcemia is life-threatening and may require management in an intensive care unit by means of medical therapy consisting of volume expansion, loop diuretics, cinacalcet, calcitonin and bisphosphonates. Renal replacement therapy such as intermittent hemodialysis has been successfully used among patients with severe hypercalcemia who become refractory to medi...
Source: European Journal of Medical Research - June 8, 2022 Category: Research Source Type: research

Medical News Today: ESMO GI provides new insights into HCC and metastatic liver cancer
We report new findings on carcinoma and liver cancer from the European Society for Medical Oncology 17th World Congress on Gastrointestinal cancer in Barcelona, Spain.
Source: Health News from Medical News Today - July 12, 2015 Category: Consumer Health News Tags: Conferences Source Type: news

Effectiveness and safety of cabazitaxel chemotherapy for metastatic castration-resistant prostatic carcinoma on Turkish patients (The Anatolian Society of Medical Oncology).
CONCLUSIONS: This study reflects toxicity profile of Turkish patients as a Caucasian race. We suggest that cabazitaxel is a safe and effective treatment option for mCRPC patients who progress after docetaxel. Moreover, ethnicity may play important roles both in treatment response and in toxicity profile. PMID: 27097941 [PubMed - in process]
Source: European Review for Medical and Pharmacological Sciences - April 23, 2016 Category: Drugs & Pharmacology Tags: Eur Rev Med Pharmacol Sci Source Type: research

The Influence of Disease Severity of Preceding Clinical Cases on Pathologists Medical Decision Making
Conclusion. Physicians appear to be influenced by the severity of previously interpreted test cases. Understanding types and sources of diagnostic bias may lead to improved assessment of accuracy and better patient care.
Source: Medical Decision Making - November 28, 2016 Category: Health Management Authors: Frederick, P. D., Nelson, H. D., Carney, P. A., Brunye, T. T., Allison, K. H., Weaver, D. L., Elmore, J. G. Tags: Original Articles Source Type: research

Assessment of cetuximab-induced infusion reactions and administration rechallenge at an academic medical center
AbstractCetuximab is approved for treatment of squamous cell carcinoma of the head and neck (SCCHN). Cetuximab is generally well tolerated, but does carry a black box warning for infusion reactions (IRs). Incidence of IR in clinical trials was 15 –20% for all grades and 3–5% for grades III–IV. Retrospective studies reported a higher incidence of all grade IRs and grades III–IV IR in areas of the Southeastern United States. Information regarding rechallenge doses after an IR has not been well described. At our institution, we frequent ly rechallenge on the same day after an initial IR. The primary objective was to d...
Source: Medical Oncology - February 21, 2017 Category: Cancer & Oncology Source Type: research

Screening for thyroid diseases among students of applied medical sciences at King Abdulaziz University, Saudi Arabia.
CONCLUSION: Ultrasonography is a useful and effective technique for screening thyroid related diseases, and can be utilized as a routine practice for general population screening. PMID: 29543312 [PubMed - in process]
Source: Saudi Medical Journal - March 17, 2018 Category: Middle East Health Tags: Saudi Med J Source Type: research

Treatment patterns and direct medical costs among patients with advanced hepatocellular carcinoma.
Conclusions: In patients who received first-line therapy for HCC, the duration of therapy was short (potentially due to progression or tolerability). Most patients did not continue to second-line therapy. Despite the short duration of therapy, HCC patients still incur a high economic burden, and there is a need for more effective and tolerable treatments. PMID: 32969741 [PubMed - as supplied by publisher]
Source: Current Medical Research and Opinion - September 26, 2020 Category: Research Tags: Curr Med Res Opin Source Type: research

Novel 5 ‐point 18‐FDG‐PET/CT visual scoring system for assessing treatment response in patients with oesophageal or gastro‐oesophageal junction carcinoma
ConclusionQualitative assessment of oesophageal and GOJ cancers utilising FDG ‐PET is reproducible and may be able to prognosticate outcomes in patients undergoing treatment. Prospective validation is required.
Source: Journal of Medical Imaging and Radiation Oncology - October 15, 2020 Category: Radiology Authors: Edward Cong, Andrew J Oar, Mark T Lee, Andrew Chicco, Michael Lin, June Yap, Peter Lin, Ivan Ho Shon Tags: MEDICAL IMAGING –ORIGINAL ARTICLE Source Type: research

Integrated digital pathology at scale: A solution for clinical diagnostics and cancer research at a large academic medical center
ConclusionsWe highlight major challenges and lessons learned when going digital to provide orientation for other pathologists. Building interconnected solutions will not only increase adoption of DP, but also facilitate next-generation computational pathology at scale for enhanced cancer research.
Source: Journal of the American Medical Informatics Association - July 14, 2021 Category: Information Technology Source Type: research

Chasing Zero Harm in Radiation Oncology: Using Pre-treatment Peer Review
Conclusions: Catching errors prior to treatment is the only way to “chase zero” in radiation oncology. Various types of errors may exist in treatment plans and our GCPR model succeeds in preventing many errors of all shapes and sizes in target definition, dose prescriptions, and treatment plans from ever reaching the patients. Background and Introduction Since the release of the seminal report from the Institute of Medicine (IOM) titled, “To Err is Human,” in 1999, the importance of patient safety and avoiding medical errors have been recognized and endorsed by the physician communit...
Source: Frontiers in Oncology - April 23, 2019 Category: Cancer & Oncology Source Type: research

Assessment of Knowledge, Attitude, and Practice Regarding Oral Cancer among Dental Graduates —A Web-Based Survey
This study revealed that the majority of the new dental clinicians were not having legitimate knowledge regarding oral cancer. Thus, this lacuna in knowledge and skills can be eliminated by conducting workshops and continuing education programs. This may subsequently aid to improve patient care.
Source: Journal of Cancer Education - January 14, 2021 Category: Cancer & Oncology Source Type: research

Comparative analysis of online patient education material pertaining to hepatitis and its complications
Conclusion: Patient reading materials reviewed in this study were written well above the recommended reading grade level. These findings suggest review of patient education materials in an effort to close the gap between the average reading level and the reading materials.
Source: European Journal of Gastroenterology and Hepatology - March 31, 2016 Category: Gastroenterology Tags: Original Articles: Hepatitis Source Type: research

Basket Trials for Intractable Cancer
This study has made a significant impact on clinical practice in cancer patients harboring the TRK translocation, and also illustrates the potential for future advancements in drug development and clinical trials of cancers harboring rare genomic alterations (50). Second, a basket trial may allow screening for potential efficacy across multiple tumor types in order to guide more traditional, disease-specific, follow-up studies. The goal of some basket trials is to obtain an overall assessment of the drug with pooled histologies; in such trials, subsequent analyses are straightforward, and are comparable to those in standa...
Source: Frontiers in Oncology - April 11, 2019 Category: Cancer & Oncology Source Type: research