Basket Trials for Intractable Cancer

This study was supported by the Shanghai Sailing Program [grant number 17YF1425200, 2017]; Chinese National Natural Science Funding [grant number 81702249, 2017]; Science and Technology Commission of Shanghai Municipality [grant number 17511103403, 2017]; The funder has no role in the study design, data collection and analysis, decision to publish, or preparation of the manuscript. Conflict of Interest Statement The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest. Acknowledgments We acknowledge the experts from Refractory Malignancy Society of Chinese Medical Education Association for the consultation. References 1. Tao JJ, Schram AM, Hyman DM. Basket studies: redefining clinical trials in the era of genome-driven oncology. Annu Rev Med. (2018) 69:319–31. doi: 10.1146/annurev-med-062016-050343 PubMed Abstract | CrossRef Full Text | Google Scholar 2. Mcneil C. NCI-MATCH launch highlights new trial design in precision-medicine era. J Natl Cancer Inst. (2015) 107:djv193. doi: 10.1093/jnci/djv193 PubMed Abstract | CrossRef Full Text | Google Scholar 3. Chapman PB, Hauschild A, Robert C, Haanen JB, Ascierto P, Larkin J, et al. Improved survival with vemurafenib in melanoma with BRAF V600E mutation. N Engl J Med. (2011) 364:2507–16. doi: 10.1056/NEJMoa1103782 PubMed Abstract | CrossRef Full Text | Google Scholar 4. Hainsworth JD...
Source: Frontiers in Oncology - Category: Cancer & Oncology Source Type: research

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