Basket Trials for Intractable Cancer
This study was supported by the Shanghai Sailing Program [grant number 17YF1425200, 2017]; Chinese National Natural Science Funding [grant number 81702249, 2017]; Science and Technology Commission of Shanghai Municipality [grant number 17511103403, 2017]; The funder has no role in the study design, data collection and analysis, decision to publish, or preparation of the manuscript. Conflict of Interest Statement The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest. Acknowledgments We acknowledge the experts from Refractory Malignancy Society of Chinese Medical Education Association for the consultation. References 1. Tao JJ, Schram AM, Hyman DM. Basket studies: redefining clinical trials in the era of genome-driven oncology. Annu Rev Med. (2018) 69:319–31. doi: 10.1146/annurev-med-062016-050343 PubMed Abstract | CrossRef Full Text | Google Scholar 2. Mcneil C. NCI-MATCH launch highlights new trial design in precision-medicine era. J Natl Cancer Inst. (2015) 107:djv193. doi: 10.1093/jnci/djv193 PubMed Abstract | CrossRef Full Text | Google Scholar 3. Chapman PB, Hauschild A, Robert C, Haanen JB, Ascierto P, Larkin J, et al. Improved survival with vemurafenib in melanoma with BRAF V600E mutation. N Engl J Med. (2011) 364:2507–16. doi: 10.1056/NEJMoa1103782 PubMed Abstract | CrossRef Full Text | Google Scholar 4. Hainsworth JD...
Many experts now view the individual mandate as a policy that did little to increase health coverage — but did a lot to invite political backlash.
Authors: Park JS, Bae SH PMID: 32937686 [PubMed - as supplied by publisher]
CONCLUSIONS: The COI of liver diseases in Japan has been decreasing for the past 15 years. In the future, a further reduction in patients with hepatitis C is expected, and even if the incidence of NASH and alcoholic liver disease increases, that of cirrhosis and liver cancer will likely continue to decrease. PMID: 32942026 [PubMed - as supplied by publisher]
CONCLUSION: To ensure patient satisfaction and high quality of life, an accurate diagnosis for vertigo or dizziness is required; therefore, methods or materials to improve the diagnostic accuracy are needed. PMID: 32940200 [PubMed - as supplied by publisher]
Publication date: December 2020Source: Nano Today, Volume 35Author(s): Tanziela Tanziela, Sana Shaikh, Hui Jiang, Zuhong Lu, Xuemei Wang
Publication date: Available online 18 September 2020Source: Progress in Natural Science: Materials InternationalAuthor(s): Pengyu Zhao, Yaqin Liu, Tian Li, Yanling Zhou, Sander Leeflang, Lei Chen, Chengtie Wu, Jie Zhou, Zhiguang Huan
Publication date: February 2021Source: Materials Science and Engineering: C, Volume 119Author(s): Nele Pien, Ian Peeters, Liesbet Deconinck, Lana Van Damme, Lieven De Wilde, Ann Martens, Sandra Van Vlierberghe, Peter Dubruel, Arn Mignon
Publication date: November–December 2020Source: Journal of Materials Research and Technology, Volume 9, Issue 6Author(s): Reza Eivazzadeh-Keihan, Fateme Radinekiyan, Somayeh Asgharnasl, Ali Maleki, Hossein Bahreinizad
Publication date: 17 September 2020Source: Cell, Volume 182, Issue 6Author(s): Andrew L. Ji, Adam J. Rubin, Kim Thrane, Sizun Jiang, David L. Reynolds, Robin M. Meyers, Margaret G. Guo, Benson M. George, Annelie Mollbrink, Joseph Bergenstråhle, Ludvig Larsson, Yunhao Bai, Bokai Zhu, Aparna Bhaduri, Jordan M. Meyers, Xavier Rovira-Clavé, S. Tyler Hollmig, Sumaira Z. Aasi, Garry P. Nolan, Joakim Lundeberg
Conclusion Snoring was shown to be a frequent pathophysiology in active workers. It was a health indicator for active workers, and especially in men, intervention for snoring may reduce the risk of developing lifestyle-related diseases. PMID: 32938849 [PubMed - in process]
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