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Total 468 results found since Jan 2013.

Causes of death in atrial fibrillation: Challenges and opportunities
Atrial fibrillation (AF) is an age-related arrhythmia associated with several co-morbidities and significant mortality. Most AF patients are in need of anticoagulation due to increased risk of stroke. Despite anticoagulation, AF patients still have a significant risk of death (about 5% per year). Approximately half of deaths in AF are due to heart-related causes (i.e.: sudden death, heart failure, myocardial infarction), one third of deaths are due to non-vascular causes (i.e.: cancer, respiratory diseases, infections, etc) and the remaining AF patients die from stroke or hemorrhage (about 6% each), or other causes.
Source: Trends in Cardiovascular Medicine - May 10, 2017 Category: Cardiology Authors: Antonio G ómez-Outes, Ma Luisa Suárez-Gea, Jose Manuel García-Pinilla Source Type: research

Blood Pressure Trajectories and the Risk of Intracerebral Hemorrhage and Cerebral InfarctionNovelty and Significance Epidemiology/Population
The association between long-term blood pressure (BP) patterns in community-dwelling adults and risk of intracerebral hemorrhage and cerebral infarction is not well characterized. This prospective study included 79 385 participants, free of stroke, myocardial infarction, and cancer in or before 2010 (baseline). Systolic BP trajectories were identified using latent mixture modeling with data from 2006, 2008, and 2010. Incident cases of intracerebral hemorrhage and cerebral infarction occurred during 2010 to 2014, confirmed by review of medical records, by 3 physicians. We identified 5 distinct systolic BP trajectories durin...
Source: Hypertension - August 9, 2017 Category: Cardiology Authors: Weijuan Li, Cheng Jin, Anand Vaidya, Yuntao Wu, Kathryn Rexrode, Xiaoming Zheng, Mahmut E. Gurol, Chaoran Ma, Shouling Wu, Xiang Gao Tags: Cardiovascular Disease, Epidemiology, High Blood Pressure Original Articles Source Type: research

Cardiorespiratory Fitness and Cardiovascular Disease Prevention: an Update
AbstractPurpose of ReviewCardiovascular diseases account for nearly one third of all deaths globally. Improving exercise capacity and cardiorespiratory fitness (CRF) has been an important target to reduce cardiovascular events. In addition, the American Heart Association defined decreased physical activity as the fourth risk factor for coronary artery disease. Multiple large cohort studies have evaluated the impact of CRF on outcomes. In this review, we will discuss the role of CRF in reducing cardiovascular morbidity and mortality.Recent FindingsRecent data suggest that CRF has an important role in reducing not only cardi...
Source: Current Atherosclerosis Reports - January 16, 2018 Category: Cardiology Source Type: research

Anticoagulant Agents for Atrial Fibrillation in Cancer Patients
In a recent article in the journal, Patell et al1 found CHADS2 and CHA2DS2VASC to predict risk of ischemic stroke in cancer patients with baseline atrial fibrillation (AF). Although only 36% of patients received anticoagulant therapy, the risk of stroke generally appeared to be lower than in cancer-free individuals2,3. Given the size and statistical rigor of the analysis, and the perplexing paucity of published data regarding the management of coexisting AF and cancer, the study by Patell et al1 is of outstanding worth.
Source: The American Journal of Cardiology - February 3, 2018 Category: Cardiology Authors: Marc Sorigue, Edurne Sarrate, Mireia Franch-Sarto, Mireia Santos-Gomez, Elisa Orna Source Type: research

Serum Beta Carotene and Overall and Cause-Specific Mortality.
CONCLUSIONS: This study provides evidence that higher beta carotene biochemical status is associated with lower overall, cardiovascular disease, heart disease, stroke, cancer, and other causes of mortality. The dose-response associations over a 30-year period were not attenuated by adjustment for other important risk factors and support greater fruit and vegetable consumption as a means to increase beta carotene status and promote longevity. PMID: 30566060 [PubMed - in process]
Source: Circulation Research - December 7, 2018 Category: Cardiology Authors: Huang J, Weinstein SJ, Yu K, Männistö S, Albanes D Tags: Circ Res Source Type: research

MI, Stroke Risks Rise Months Before Cancer Diagnosis MI, Stroke Risks Rise Months Before Cancer Diagnosis
About 5 months before a cancer diagnosis, the risk for arterial thromboembolism increases and continues to climb as the diagnosis date draws closer.Medscape Medical News
Source: Medscape Cardiology Headlines - December 27, 2018 Category: Cardiology Tags: Hematology-Oncology News Source Type: news

Nut Consumption in Relation to Cardiovascular Disease Incidence and Mortality among Patients with Diabetes Mellitus.
CONCLUSIONS: Higher consumption of nuts, especially tree nuts, is associated with lower CVD incidence and mortality among participants with diabetes. These data provide novel evidence that supports the recommendation of incorporating nuts into healthy dietary patterns for the prevention of CVD complications and premature deaths among individuals with diabetes. PMID: 30776978 [PubMed - as supplied by publisher]
Source: Circulation Research - February 19, 2019 Category: Cardiology Authors: Liu G, Guasch-Ferre M, Hu Y, Li Y, Hu FB, Rimm EB, Manson JE, Rexrode K, Sun Q Tags: Circ Res Source Type: research

Apr 19 2019 This Week in Cardiology Apr 19 2019 This Week in Cardiology
Anticoagulation for embolic stroke of unknown origin, added-sugar labels, AF-patient knowledge, LDL-C and hemorrhagic stroke, and genetic signals in cancer-care cardiomyopathy are discussed this week.theheart.org on Medscape
Source: Medscape Cardiology Headlines - April 19, 2019 Category: Cardiology Tags: Cardiology Commentary Source Type: news

Comparative effectiveness of rivaroxaban versus a vitamin K antagonist in patients with renal impairment treated for non-valvular atrial fibrillation in Germany — A retrospective cohort study
ConclusionThe prescription of rivaroxaban in patients with NVAF and renal impairment was associated with a lower incidence of ischaemic stroke and intracranial haemorrhage versus phenprocoumon in patients without evidence of cancer.
Source: IJC Heart and Vasculature - May 9, 2019 Category: Cardiology Source Type: research

Blood pressure levels and risk of cardiovascular disease mortality among Japanese men and women: the Japan Collaborative Cohort Study for Evaluation of Cancer Risk (JACC Study)
Conclusion: BP categories at baseline were linearly and positively associated with CVD mortality overall and also among participants not taking antihypertensive medication. A higher risk of mortality from CVD was observed among patients already treated for hypertension with optimal and normal BPs than those with high-normal BP, suggesting the importance of careful monitoring of BP and comorbidities of such patients.
Source: Journal of Hypertension - May 30, 2019 Category: Cardiology Tags: ORIGINAL PAPERS: Epidemiology Source Type: research

Efficacy and safety of oral anticoagulants in atrial fibrillation patients with cancer —a network meta-analysis
AbstractThere are no guideline recommendations for the use of anticoagulant therapy in atrial fibrillation (AF) patients with cancer, which creates uncertainty about the optimal antithrombotic treatment in these patients. We conducted a network meta-analysis for the first time to assess the efficacy and safety of anticoagulant drugs in patients with AF and concurrent cancer. The PubMed, EMBASE, and Cochrane databases were searched up to March 2019. A search was made for the main anticoagulant drugs (warfarin, dabigatran, apixaban, rivaroxaban, and edoxaban). Outputs were presented as odds ratios (ORs), their corresponding ...
Source: Heart Failure Reviews - August 12, 2019 Category: Cardiology Source Type: research

Treatment of hypertension in old patients without previous cardiovascular disease
Conclusion: Blood pressure levels lower than those currently recommended are not harmful among older patients. The association between lower SBP and lesser risk of CVD may instead suggest a beneficial effect of lower SBP.
Source: Journal of Hypertension - September 30, 2019 Category: Cardiology Tags: ORIGINAL PAPERS: Treatment Source Type: research

Vitamin D, Marine n-3 Fatty Acids, and Primary Prevention of Cardiovascular Disease Current Evidence.
Abstract Whether marine omega-3 fatty acid (n-3 FA) or vitamin D supplementation can prevent cardiovascular disease (CVD) in general populations at usual risk for this outcome is unknown. A major goal of VITAL (Vitamin D and Omega-3 Trial) was to fill this knowledge gap. In this article, we review the results of VITAL, discuss relevant mechanistic studies regarding n-3 FAs, vitamin D, and vascular disease, and summarize recent meta-analyses of the randomized trial evidence on these agents. VITAL was a nationwide, randomized, placebo-controlled, 2×2 factorial trial of marine n-3 FAs (1 g/d) and vitamin D3 (2000 IU...
Source: Circulation Research - January 2, 2020 Category: Cardiology Authors: Manson JE, Bassuk SS, Cook NR, Lee IM, Mora S, Albert CM, Buring JE, VITAL Research Group Tags: Circ Res Source Type: research

The link of depression, untreated hypertension, and diabetes with mortality in postmenopausal women: A cohort study.
Conclusions It is suggested we should take sufficient care of postmenopausal females with depression and control blood pressure and glucose more effectively. Abbreviations HP: Hypertension; DM: Diabetes; TC: Cholesterol; TG: Triglyceride; BMI: Body-Mass Index; CES-D: Center for Epidemiologic Studies Depression; CDC: Centers for Disease Control and Prevention; HR: Hazard Ratio; CI: Confidence Interval; ADL: Activities of daily living scale. PMID: 32715792 [PubMed - as supplied by publisher]
Source: Clinical and Experimental Hypertension - July 26, 2020 Category: Cardiology Authors: Guan S, Fang X, Gu X, Zhang Z, Tang Z, Wu X, Liu H, Wang C Tags: Clin Exp Hypertens Source Type: research

Direct oral Xa inhibitors versus warfarin in patients with cancer and atrial fibrillation: a meta-analysis
Conclusion In patients with cancer and atrial fibrillation, direct oral Xa inhibitors have a similar efficacy and may be safer compared with warfarin. These results are consistent both in patients with active cancer and history of cancer.
Source: Journal of Cardiovascular Medicine - July 30, 2020 Category: Cardiology Tags: Research articles: Arrhythmias Source Type: research