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Total 872 results found since Jan 2013.

New and cost effective cell-based assay for Dialyzed Leukocyte Extract (DLE)-induced Jurkat cells proliferation under azathioprine treatment
In conclusion, our new cell-based MTT assay has excellent DLE biological activity consistency, robustness and is cost effective, presenting important advantages over previous DLE activity in vitro and in vivo assays.
Source: Journal of Pharmaceutical and Biomedical Analysis - February 10, 2017 Category: Drugs & Pharmacology Source Type: research

Molecules, Vol. 22, Pages 292: Wine Flavonoids in Health and Disease Prevention
Wine, and particularly red wine, is a beverage with a great chemical complexity that is in continuous evolution. Chemically, wine is a hydroalcoholic solution (~78% water) that comprises a wide variety of chemical components, including aldehydes, esters, ketones, lipids, minerals, organic acids, phenolics, soluble proteins, sugars and vitamins. Flavonoids constitute a major group of polyphenolic compounds which are directly associated with the organoleptic and health-promoting properties of red wine. However, due to the insufficient epidemiological and in vivo evidences on this subject, the presence of a high number of var...
Source: Molecules - February 13, 2017 Category: Chemistry Authors: Iva Fernandes Rosa P érez-Gregorio Susana Soares Nuno Mateus Victor de Freitas Tags: Article Source Type: research

Fasting For Just Five Days A Month Linked To Health Improvements
(Reuters Health) – Following a diet that mimics fasting may reduce risk factors for disease in generally healthy people, according to a small study.  Dr. Min Wei of UCLA’s Longevity Institute and colleagues tested the effects of the fasting-mimicking diet on various risk factors for diabetes, heart disease, cancer or other conditions. The diet (FMD; brand name ProLon) is low in calories, sugars and protein but high in unsaturated fats. Forty-eight study participants ate normally for three months while 52 ate FMD for five days each month and ate normally the rest of the time. After three months, the groups ...
Source: Healthy Living - The Huffington Post - February 21, 2017 Category: Consumer Health News Source Type: news

Phaleria macrocarpa (Boerl.) Fruit induce G0/G1 and G2/M cell cycle arrest and apoptosis through mitochondria-mediated pathway in MDA-MB-231 Human Breast Cancer Cell
Conclusion The results indicated that PMEAF treatment induced apoptosis in MDA-MB-231 cells through intrinsic mitochondrial related pathway with the participation of pro and anti-apoptotic proteins, caspases, G0/G1 and G2/M-phases cell cycle arrest by p53-mediated mechanism. Graphical abstract
Source: Journal of Ethnopharmacology - March 1, 2017 Category: Drugs & Pharmacology Source Type: research

A prospective randomized trial comparing patent blue and methylene blue for the detection of the sentinel lymph node in breast cancer patients
Conclusion: Methylene blue performed as well as patent blue in identifying the SLN in breast cancer patients.Resumo Introdu ção: O azul de metileno é mais facilmente encontrado para comercialização e a um preço menor que o azul patente. Parece ainda haver menor risco de anafilaxia. Objetivo: Comparar a taxa de detecção do linfonodo sentinela com o azul patente e com o azul de metileno. Método: Foram incluídas , de forma randomizada e prospectiva, 142 pacientes com diagnóstico de carcinoma mamário invasor, que consentiram em participar livremente do estudo. Foram injetados 2 mL de azul patente (grupo A) em 69 (4...
Source: Revista da Associacao Medica Brasileira - March 24, 2017 Category: Journals (General) Source Type: research

Dr Trevor Cates on harmful chemicals in beauty products
Leading Utah-based naturopathic doctor Trevor Cates lists the 20 most harmful hidden ingredients to look out - many linked with cancer, hormone disruption, lung disease and allergies.
Source: the Mail online | Health - April 5, 2017 Category: Consumer Health News Source Type: news

Vitamin D requirements in infancy: a systematic review
Purpose of review: New evidence for recommendations for vitamin D supplementation in healthy infants based upon recent literature. Recent findings: Randomized controlled trials published since 2009 that related to vitamin D doses in infancy were reviewed. They do not provide any additional evidence that larger, more generous amounts of daily vitamin D beyond the customary recommended 400 IU daily dose, affect any significant outcome. Larger amounts may lead to serum 25 hydroxy vitamin D concentrations that have been reported to be potentially associated with adverse effects. Summary: There are still many unanswered que...
Source: Current Opinion in Clinical Nutrition and Metabolic Care - April 5, 2017 Category: Nutrition Tags: PAEDIATRICS: Edited by Berthold Koletzko and Raanan Shamir Source Type: research

Abstract B21: The study of {beta}-glucan on the release of nitric oxide by macrophages stimulated with lipopolysaccharide
This research analyzed the effect of β-glucan that is expected to alleviate the production of the inflammatory mediator in a macrophagocyte, which was processed by the lipopolysaccharide (LPS) of Escherichia, a pathogen related to allergy. The incubated layer was used for a nitric oxide (NO) analysis. The DNA-binding activation of the small unit of NF-B was measured using the ELISA-based kit. In the RAW264.7 cells that were vitalized by E.coli LPS, the β-glucan inhibited both the combatant and rendering phases of the inducible NO synthase (iNOS)-derived NO. β-glucan increased the expression of the heme oxyge...
Source: Cancer Epidemiology Biomarkers and Prevention - April 30, 2017 Category: Cancer & Oncology Authors: Cho, K. K. Tags: Improving Cancer Risk Prediction for Prevention and Early Detection: Poster Presentations - Proffered Abstracts Source Type: research

6 Reasons Why Owning A Dog Is Good For Your Health
Having a dog offers companionship, gives you an excuse to exercise, brings you happiness and provides entertainment. But did you know that owning a dog can also have potential health benefits, both mentally and physically, for you and your family? There is scientific evidence that touts some of the health perks of owning a pup. Take a look at how these six ways having a dog could be good for your health. 1. Stay active Dogs need to be exercised. They can’t be cooped up all day without having the chance to get up and run around. Having a dog encourages owners to take them for walks, play fetch, and get moving. And we all...
Source: Healthy Living - The Huffington Post - May 3, 2017 Category: Consumer Health News Source Type: news

Two Washington state Republicans voted against Obamacare repeal
Two of the 20 House Republicans who voted against the health care bill to repeal and replace parts of the Affordable Care Act are from Washington state. The House passed the American Health Care Act Thursday by a vote of 217 to 213. All Democrats voted against the bill. The Republican proposal would allow health insurers to charge higher premiums for older customers or those with pre-existing health conditions ranging from allergies to cancer, el iminate minimum coverage requirements and a rule…
Source: bizjournals.com Health Care:Pharmaceuticals headlines - May 4, 2017 Category: Pharmaceuticals Authors: Coral Garnick Source Type: news

Sun protection strategies
About 5% of sunlight is ultraviolet (UV). UV causes gene mutations in skin cells, and is the main cause of all forms of skin cancer. Sun protection is crucial for people at high risk of malignant melanoma: those with fair skin, who are moley or have a family history of melanoma. Sun protection is required in patients at risk of squamous and basal cell skin cancers, and is vital in patients with sunlight allergies. There is no agreement about how much sun protection is advisable for healthy adults at low risk of skin cancer.
Source: Medicine - May 17, 2017 Category: Internal Medicine Authors: Robert Sarkany Tags: Photoprotection of the skin Source Type: research

Cancer drug may prevent reactions to airborne allergens
A new cancer drug may provide significant reduction in allergic reactions in people with airborne seasonal allergies, according to a new study.
Source: Health News - UPI.com - May 22, 2017 Category: Consumer Health News Source Type: news

Stressor-driven extracellular acidosis as tumor inducer via aberrant enzyme activation: A review on the mechanisms and possible prophylaxis.
Abstract When the extracellular pH of the human body vacillates in either direction, tissue homeostasis is compromised. Fluctuations in acidosis have been linked to a wide variety of pathological conditions, including bone loss, cancer, allergies, and auto-immune diseases. Stress conditions may affect oxygen tension and hypoxia modulates the expression and/or activity of membrane tethered transporters/pumps, transcription factors, enzymes and intercellular junctions. These modifications provoke erratic gene expression, aberrant tissue remodeling and oncogenesis. While physiological optimization of pH in tissues is...
Source: Gene - May 22, 2017 Category: Genetics & Stem Cells Authors: Patel S Tags: Gene Source Type: research

Trumpcare Threatens The Health And Future Of Young People
Millennials have seen dramatic gains in health insurance coverage since passage of the ACA, more so than any other age demographic. Instead of building on these historic gains, Trumpcare would have devastating effects on young people. Trumpcare harms young people by eliminating the current tax credit that helps many young people purchase insurance. According to Young Invincibles, low- and moderate-income young individuals would pay more under Trumpcare than under current law, ultimately impacting over 4 million young people and harming the lowest-income young people the most. On top of that, Trumpcare allows insurers to im...
Source: Healthy Living - The Huffington Post - June 7, 2017 Category: Consumer Health News Source Type: news

Activated Natural Killer Cells Mediate the Suppressive Effect of Interleukin-4 on Tumor Development via STAT6 Activation in an Atopic Condition Melanoma Model.
Abstract A protective effect of allergy for cancer has been suggested, but the results are somewhat conflicting, and the mechanism remains elusive. Interleukin-4 (IL-4) signaling has been identified as a potentially important pathway in the development of allergies and the suppression of cancer development. To evaluate the allergy responses in IL-4-mediated tumor development, we compared the growth of B16F10 melanoma cells in 4% phthalic anhydride (PA)-treated IL-4/Luc/CNS-1 transgenic mice (IL-4 mice) and acetone-olive oil (AOO)-treated IL-4 mice as a control for 3 weeks. Much higher allergic responses and natura...
Source: Neoplasia - June 3, 2017 Category: Cancer & Oncology Authors: Son DJ, Jung YY, Park MH, Lee HL, Song MJ, Yoo HS, Hwang DY, Han SB, Hong JT Tags: Neoplasia Source Type: research