Propofol Infusion Syndrome Following Endoscopic Tracheoplasty and Jet Ventilation: Case Report
CONCLUSIONS: Propofol is often used as an anesthetic for jet ventilation during otolaryngologic airway surgery. Propofol related infusion syndrome is an uncommon but life-threatening peri-operative complication that should be considered in any patient with an unusual post-operative recovery characterized by metabolic acidosis, ECG changes, end organ damage, and elevated lactate.PMID:38183238 | DOI:10.1177/00034894231223574 (Source: The Annals of Otology, Rhinology, and Laryngology)
Source: The Annals of Otology, Rhinology, and Laryngology - January 6, 2024 Category: ENT & OMF Authors: Bonnie Chen Andrew Tran Mohammed Alnijoumi Mark R Gilbert Source Type: research
Propofol Infusion Syndrome Following Endoscopic Tracheoplasty and Jet Ventilation: Case Report
CONCLUSIONS: Propofol is often used as an anesthetic for jet ventilation during otolaryngologic airway surgery. Propofol related infusion syndrome is an uncommon but life-threatening peri-operative complication that should be considered in any patient with an unusual post-operative recovery characterized by metabolic acidosis, ECG changes, end organ damage, and elevated lactate.PMID:38183238 | DOI:10.1177/00034894231223574 (Source: The Annals of Otology, Rhinology, and Laryngology)
Source: The Annals of Otology, Rhinology, and Laryngology - January 6, 2024 Category: ENT & OMF Authors: Bonnie Chen Andrew Tran Mohammed Alnijoumi Mark R Gilbert Source Type: research
Dyskinesia-hyperpyrexia syndrome in Parkinson's disease triggered by overdose of levodopa — a case report and literature review
Dyskinesia-hyperpyrexia syndrome, a rare medical emergency in Parkinson's disease, is first described in 2010. It is characterized by severe continuous dyskinesia associated with rhabdomyolysis, hyperthermia and subsequent alteration of the mental state. Gradual reduction of dopaminergic dose or DBS is recommended treatment. The prognosis is usually good, but sometimes fatal. But so far, this potentially fatal complication is not widely recognized by clinicians. In emergency, if clinicians fail to make prompt diagnosis and treatment, patients' conditions may get worse, and their lives may be threatened in serious cases. (S...
Source: Frontiers in Neurology - January 5, 2024 Category: Neurology Source Type: research
Incidence and outcome of laryngeal edema and rhabdomyolysis after ingestion of black rock
ConclusionPDD toxicity is more frequent in younger females. The intoxication from the black rock is increasingly used in suicide attempts and vital organs are usually affected especially the kidney, liver, and heart causing morbidity and mortality. (Source: International Journal of Emergency Medicine)
Source: International Journal of Emergency Medicine - January 2, 2024 Category: Emergency Medicine Source Type: research
819 Trends and outcomes in deliveries affected by maternal fatty acid oxidation defects
Improved detection and management of fatty acid oxidation defects (FAOD) over time has led to increased survival to reproductive age. National data is needed on the prevalence and obstetric outcomes for this group of patients, given the potential increased risk of complications such as hypoglycemia or rhabdomyolysis related to the metabolic stress of labor and delivery. (Source: American Journal of Obstetrics and Gynecology)
Source: American Journal of Obstetrics and Gynecology - January 1, 2024 Category: OBGYN Authors: Matthew Shear, Teresa N. Sparks, Renata Gallagher, Kate Swanson, Mary E. Norton, Anna Farooqi, Timothy Wen Source Type: research
Plants Causing Toxic Myopathies
Boxelder and sycamore maple contain hypoglycin A (HGA), the toxic metabolite of which, MCPA-CoA, inhibits fatty acid β-oxidation, causing seasonal pasture myopathy (SPM) or atypical myopathy (AM), respectively. White snakeroot and rayless goldenrod contain multiple benzofuran ketones (BFKs). The identity/toxicity of BFKs appear variable, possibly involving interactions between toxins/toxic metabolites, but ultima tely inhibit cellular energy metabolism. Unthrifty horses grazing sparse pastures during the fall appear predisposed to these plant-associated, frequently fatal, toxic myopathies. Toxidromes are characterized by ...
Source: Veterinary Clinics of North America: Equine Practice - December 26, 2023 Category: Veterinary Research Authors: Beatrice Sponseller, Tim Evans Source Type: research
Traumatic Rhabdomyolysis: Crush Syndrome, Compartment Syndrome, and the 'Found Down' Patient
J Am Acad Orthop Surg. 2023 Dec 13. doi: 10.5435/JAAOS-D-23-00734. Online ahead of print.ABSTRACTTraumatic rhabdomyolysis is a systemic manifestation of muscle injury and can occur from various traumatic etiologies, including crush syndrome (CrshS) and compartment syndrome (CS). Although historically described in natural disaster survivors trapped under collapsed structures, the frequency of CrshS has increased in the setting of 'found down' patients from opioid overdoses. Signs and symptoms of the injured limb in CrshS may range from pressure-induced skin changes to neurologic deficits and paralysis. Although its pathophy...
Source: The Journal of the American Academy of Orthopaedic Surgeons - December 18, 2023 Category: Orthopaedics Authors: John J Fernandez Shelby R Smith Source Type: research
Before attributing rhabdomyolysis to bedding during surgery, alternative etiologies must be ruled out
Asian J Surg. 2023 Dec 15:S1015-9584(23)01965-6. doi: 10.1016/j.asjsur.2023.12.001. Online ahead of print.NO ABSTRACTPMID:38104009 | DOI:10.1016/j.asjsur.2023.12.001 (Source: Asian Journal of Surgery)
Source: Asian Journal of Surgery - December 16, 2023 Category: Surgery Authors: Josef Finsterer Sounira Mehri Source Type: research
Before attributing rhabdomyolysis to bedding during surgery, alternative etiologies must be ruled out
Asian J Surg. 2023 Dec 15:S1015-9584(23)01965-6. doi: 10.1016/j.asjsur.2023.12.001. Online ahead of print.NO ABSTRACTPMID:38104009 | DOI:10.1016/j.asjsur.2023.12.001 (Source: Asian Journal of Surgery)
Source: Asian Journal of Surgery - December 16, 2023 Category: Surgery Authors: Josef Finsterer Sounira Mehri Source Type: research
Exercise-induced rhabdomyolysis manifestations and complications: a case report
CONCLUSION: Awareness campaigns need to be conducted to educate the public about healthy ways to exercise, such as gradually increasing the intensity of physical activity, warming up before exercising, cooling down after each workout, and staying hydrated. It is important that healthcare providers, trainees and trainers are able to recognize the signs of muscular injury following vigorous exercise in order to reduce the incidences of complications that could be deadly if they are not caught and managed early.PMID:38098573 | PMC:PMC10718356 | DOI:10.1097/MS9.0000000000001479 (Source: Annals of Medicine)
Source: Annals of Medicine - December 15, 2023 Category: Internal Medicine Authors: Kholoud F Alharbi Manal Z Alfahmi Source Type: research
18 Months of Treatment with Triheptanoin in 2 Patients with Long Chain Fatty Acid Oxidation Disorders
CONCLUSION: In our patients, we could observe a reduction in the number of admissions, and less severe rhabdomyolysis crises after THP use. The weight gain was significant. There were no major side effects. Despite regarding only two patients, our findings are in line with the latest literature on THP and LC-FAOD, reinforcing the utility of THP as one more tool in the treatment of these disorders with rhabdomyolysis as the main manifestation. The weight increase is an issue to be aware of and to address from the start of the treatment.PMID:38093447 | DOI:10.2174/0118715303279681231122104925 (Source: Endocrine, Metabolic an...
Source: Endocrine, Metabolic and Immune Disorders Drug Targets - December 14, 2023 Category: Endocrinology Authors: Helena Santos Ana Vieira Joana Tenente Ana Carri ço Esmeralda Rodrigues Source Type: research
