Proteomic analysis of multiple organ dysfunction induced by rhabdomyolysis
This study comprehensively describes the functional and structural changes of kidney, heart and lung in rats after rhabdomyolysis, analyzes the DEPs of kidney, heart and lung, and determines the key role of Serpina3n in multiple organ injury caused by rhabdomyolysis. SIGNIFICANCE: This study comprehensively describes the functional and structural changes of kidney, heart and lung in rats after rhabdomyolysis, analyzes the DEPs of kidney, heart and lung, and determines the key role of Serpina3n in multiple organ injury caused by rhabdomyolysis.PMID:38403185 | DOI:10.1016/j.jprot.2024.105138 (Source: Journal of Proteomics)
Source: Journal of Proteomics - February 25, 2024 Category: Biochemistry Authors: Yan Zhang Qiang Lyu Xiao Han Xu Wang Ran Liu Jing Hao Li Zhang Xiang-Mei Chen Source Type: research
Proteomic analysis of multiple organ dysfunction induced by rhabdomyolysis
This study comprehensively describes the functional and structural changes of kidney, heart and lung in rats after rhabdomyolysis, analyzes the DEPs of kidney, heart and lung, and determines the key role of Serpina3n in multiple organ injury caused by rhabdomyolysis. SIGNIFICANCE: This study comprehensively describes the functional and structural changes of kidney, heart and lung in rats after rhabdomyolysis, analyzes the DEPs of kidney, heart and lung, and determines the key role of Serpina3n in multiple organ injury caused by rhabdomyolysis.PMID:38403185 | DOI:10.1016/j.jprot.2024.105138 (Source: Journal of Proteomics)
Source: Journal of Proteomics - February 25, 2024 Category: Biochemistry Authors: Yan Zhang Qiang Lyu Xiao Han Xu Wang Ran Liu Jing Hao Li Zhang Xiang-Mei Chen Source Type: research
Clinical outcomes of rhabdomyolysis & amp; validation of McMahon score for risk prediction
CONCLUSIONS: Rhabdomyolysis in tropics is associated with significant organ dysfunction and mortality. Although the incidence of AKI and RRT is high, the overall renal outcome is good among survivors. The wide confidence intervals for the area under curve for McMahon score limit its predictability for RRT and mortality.PMID:38391136 | DOI:10.4103/ijmr.ijmr_2733_21 (Source: Indian J Med Res)
Source: Indian J Med Res - February 23, 2024 Category: Research Authors: Manju Mathew Subhash Chandran Bhaskaran Pillai Source Type: research
Clinical outcomes of rhabdomyolysis & amp; validation of McMahon score for risk prediction
CONCLUSIONS: Rhabdomyolysis in tropics is associated with significant organ dysfunction and mortality. Although the incidence of AKI and RRT is high, the overall renal outcome is good among survivors. The wide confidence intervals for the area under curve for McMahon score limit its predictability for RRT and mortality.PMID:38391136 | DOI:10.4103/ijmr.ijmr_2733_21 (Source: The Indian Journal of Medical Research)
Source: The Indian Journal of Medical Research - February 23, 2024 Category: Biomedical Science Authors: Manju Mathew Subhash Chandran Bhaskaran Pillai Source Type: research
Clinical outcomes of rhabdomyolysis & amp; validation of McMahon score for risk prediction
CONCLUSIONS: Rhabdomyolysis in tropics is associated with significant organ dysfunction and mortality. Although the incidence of AKI and RRT is high, the overall renal outcome is good among survivors. The wide confidence intervals for the area under curve for McMahon score limit its predictability for RRT and mortality.PMID:38391136 | DOI:10.4103/ijmr.ijmr_2733_21 (Source: Indian J Med Res)
Source: Indian J Med Res - February 23, 2024 Category: Research Authors: Manju Mathew Subhash Chandran Bhaskaran Pillai Source Type: research
Clinical outcomes of rhabdomyolysis & amp; validation of McMahon score for risk prediction
CONCLUSIONS: Rhabdomyolysis in tropics is associated with significant organ dysfunction and mortality. Although the incidence of AKI and RRT is high, the overall renal outcome is good among survivors. The wide confidence intervals for the area under curve for McMahon score limit its predictability for RRT and mortality.PMID:38391136 | DOI:10.4103/ijmr.ijmr_2733_21 (Source: The Indian Journal of Medical Research)
Source: The Indian Journal of Medical Research - February 23, 2024 Category: Biomedical Science Authors: Manju Mathew Subhash Chandran Bhaskaran Pillai Source Type: research
Clinical outcomes of rhabdomyolysis & amp; validation of McMahon score for risk prediction
CONCLUSIONS: Rhabdomyolysis in tropics is associated with significant organ dysfunction and mortality. Although the incidence of AKI and RRT is high, the overall renal outcome is good among survivors. The wide confidence intervals for the area under curve for McMahon score limit its predictability for RRT and mortality.PMID:38391136 | DOI:10.4103/ijmr.ijmr_2733_21 (Source: Indian J Med Res)
Source: Indian J Med Res - February 23, 2024 Category: Research Authors: Manju Mathew Subhash Chandran Bhaskaran Pillai Source Type: research
Clinical outcomes of rhabdomyolysis & amp; validation of McMahon score for risk prediction
CONCLUSIONS: Rhabdomyolysis in tropics is associated with significant organ dysfunction and mortality. Although the incidence of AKI and RRT is high, the overall renal outcome is good among survivors. The wide confidence intervals for the area under curve for McMahon score limit its predictability for RRT and mortality.PMID:38391136 | DOI:10.4103/ijmr.ijmr_2733_21 (Source: The Indian Journal of Medical Research)
Source: The Indian Journal of Medical Research - February 23, 2024 Category: Biomedical Science Authors: Manju Mathew Subhash Chandran Bhaskaran Pillai Source Type: research
Clinical outcomes of rhabdomyolysis & amp; validation of McMahon score for risk prediction
CONCLUSIONS: Rhabdomyolysis in tropics is associated with significant organ dysfunction and mortality. Although the incidence of AKI and RRT is high, the overall renal outcome is good among survivors. The wide confidence intervals for the area under curve for McMahon score limit its predictability for RRT and mortality.PMID:38391136 | DOI:10.4103/ijmr.ijmr_2733_21 (Source: The Indian Journal of Medical Research)
Source: The Indian Journal of Medical Research - February 23, 2024 Category: Biomedical Science Authors: Manju Mathew Subhash Chandran Bhaskaran Pillai Source Type: research
Clinical outcomes of rhabdomyolysis & amp; validation of McMahon score for risk prediction
CONCLUSIONS: Rhabdomyolysis in tropics is associated with significant organ dysfunction and mortality. Although the incidence of AKI and RRT is high, the overall renal outcome is good among survivors. The wide confidence intervals for the area under curve for McMahon score limit its predictability for RRT and mortality.PMID:38391136 | DOI:10.4103/ijmr.ijmr_2733_21 (Source: Indian J Med Res)
Source: Indian J Med Res - February 23, 2024 Category: Research Authors: Manju Mathew Subhash Chandran Bhaskaran Pillai Source Type: research
Clinical outcomes of rhabdomyolysis & amp; validation of McMahon score for risk prediction
CONCLUSIONS: Rhabdomyolysis in tropics is associated with significant organ dysfunction and mortality. Although the incidence of AKI and RRT is high, the overall renal outcome is good among survivors. The wide confidence intervals for the area under curve for McMahon score limit its predictability for RRT and mortality.PMID:38391136 | DOI:10.4103/ijmr.ijmr_2733_21 (Source: Indian J Med Res)
Source: Indian J Med Res - February 23, 2024 Category: Research Authors: Manju Mathew Subhash Chandran Bhaskaran Pillai Source Type: research
Clinical outcomes of rhabdomyolysis & amp; validation of McMahon score for risk prediction
CONCLUSIONS: Rhabdomyolysis in tropics is associated with significant organ dysfunction and mortality. Although the incidence of AKI and RRT is high, the overall renal outcome is good among survivors. The wide confidence intervals for the area under curve for McMahon score limit its predictability for RRT and mortality.PMID:38391136 | DOI:10.4103/ijmr.ijmr_2733_21 (Source: The Indian Journal of Medical Research)
Source: The Indian Journal of Medical Research - February 23, 2024 Category: Biomedical Science Authors: Manju Mathew Subhash Chandran Bhaskaran Pillai Source Type: research
Clinical outcomes of rhabdomyolysis & amp; validation of McMahon score for risk prediction
CONCLUSIONS: Rhabdomyolysis in tropics is associated with significant organ dysfunction and mortality. Although the incidence of AKI and RRT is high, the overall renal outcome is good among survivors. The wide confidence intervals for the area under curve for McMahon score limit its predictability for RRT and mortality.PMID:38391136 | DOI:10.4103/ijmr.ijmr_2733_21 (Source: Indian J Med Res)
Source: Indian J Med Res - February 23, 2024 Category: Research Authors: Manju Mathew Subhash Chandran Bhaskaran Pillai Source Type: research
Clinical outcomes of rhabdomyolysis & amp; validation of McMahon score for risk prediction
CONCLUSIONS: Rhabdomyolysis in tropics is associated with significant organ dysfunction and mortality. Although the incidence of AKI and RRT is high, the overall renal outcome is good among survivors. The wide confidence intervals for the area under curve for McMahon score limit its predictability for RRT and mortality.PMID:38391136 | DOI:10.4103/ijmr.ijmr_2733_21 (Source: The Indian Journal of Medical Research)
Source: The Indian Journal of Medical Research - February 23, 2024 Category: Biomedical Science Authors: Manju Mathew Subhash Chandran Bhaskaran Pillai Source Type: research
Clinical outcomes of rhabdomyolysis & amp; validation of McMahon score for risk prediction
CONCLUSIONS: Rhabdomyolysis in tropics is associated with significant organ dysfunction and mortality. Although the incidence of AKI and RRT is high, the overall renal outcome is good among survivors. The wide confidence intervals for the area under curve for McMahon score limit its predictability for RRT and mortality.PMID:38391136 | DOI:10.4103/ijmr.ijmr_2733_21 (Source: Indian J Med Res)
Source: Indian J Med Res - February 23, 2024 Category: Research Authors: Manju Mathew Subhash Chandran Bhaskaran Pillai Source Type: research
