Reflex Sympathetic Dystrophy Research 
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This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.The role of TGF- β signaling in muscle atrophy, sarcopenia and cancer cachexia
Gen Comp Endocrinol. 2024 Apr 10;353:114513. doi: 10.1016/j.ygcen.2024.114513. Online ahead of print.ABSTRACTSkeletal muscle, comprising a significant proportion (40 to 50 percent) of total body weight in humans, plays a critical role in maintaining normal physiological conditions. Muscle atrophy occurs when the rate of protein degradation exceeds protein synthesis. Sarcopenia refers to age-related muscle atrophy, while cachexia represents a more complex form of muscle wasting associated with various diseases such as cancer, heart failure, and AIDS. Recent research has highlighted the involvement of signaling pathways, inc...
Source: General and Comparative Endocrinology - April 11, 2024 Category: Endocrinology Authors: Xin-Qiang Lan Cheng-Jie Deng Qi-Quan Wang Li-Min Zhao Bao-Wei Jiao Yang Xiang Source Type: research
Erratum to "The blink reflex and its modulation - Part 1: Physiological mechanisms" [Clin. Neurophysiol. 160 (2024) 130-152]
Clin Neurophysiol. 2024 Apr 10:S1388-2457(24)00098-1. doi: 10.1016/j.clinph.2024.03.026. Online ahead of print.NO ABSTRACTPMID:38604903 | DOI:10.1016/j.clinph.2024.03.026 (Source: Clinical Neurophysiology)
Source: Clinical Neurophysiology - April 11, 2024 Category: Neurology Authors: Markus Kofler Mark Hallett Gian Domenico Iannetti Viviana Versace Jens Ellrich Maria J T éllez Josep Valls-Sol é Source Type: research
Neurophysiological and imaging biomarkers of lower motor neuron dysfunction in motor neuron diseases/amyotrophic lateral sclerosis: IFCN handbook chapter
Clin Neurophysiol. 2024 Mar 20;162:91-120. doi: 10.1016/j.clinph.2024.03.015. Online ahead of print.ABSTRACTThis chapter discusses comprehensive neurophysiological biomarkers utilised in motor neuron disease (MND) and, in particular, its commonest form, amyotrophic lateral sclerosis (ALS). These encompass the conventional techniques including nerve conduction studies (NCS), needle and high-density surface electromyography (EMG) and H-reflex studies as well as novel techniques. In the last two decades, new methods of assessing the loss of motor units in a muscle have been developed, that are more convenient than earlier met...
Source: Clinical Neurophysiology - April 11, 2024 Category: Neurology Authors: Cindy Shin-Yi Lin James Howells Seward Rutkove Sanjeev Nandedkar Christoph Neuwirth Yu-Ichi Noto Nortina Shahrizaila Roger G Whittaker Hugh Bostock David Burke Hatice Tankisi Source Type: research
Optimization of Xenografting Methods for Generating Human Skeletal Muscle in Mice
Cell Transplant. 2024 Jan-Dec;33:9636897241242624. doi: 10.1177/09636897241242624.ABSTRACTXenografts of human skeletal muscle generated in mice can be used to study muscle pathology and to test drugs designed to treat myopathies and muscular dystrophies for their efficacy and specificity in human tissue. We previously developed methods to generate mature human skeletal muscles in immunocompromised mice starting with human myogenic precursor cells (hMPCs) from healthy individuals and individuals with facioscapulohumeral muscular dystrophy (FSHD). Here, we examine a series of alternative treatments at each stage in order to ...
Source: Cell Transplantation - April 11, 2024 Category: Cytology Authors: Andrea O'Neill Anna Llach Martinez Amber L Mueller Weiliang Huang Anthony Accorsi Maureen A Kane David Eyerman Robert J Bloch Source Type: research
Review: Mechanisms of TIMP-3 accumulation and pathogenesis in Sorsby fundus dystrophy
Mol Vis. 2024 Mar 3;30:74-91. eCollection 2024.ABSTRACTSorsby fundus dystrophy (SFD) is a rare, inherited form of macular degeneration caused by mutations in the gene encoding tissue inhibitor of metalloproteinases 3 (TIMP-3). There are 21 mutations currently associated with SFD, with some variants (e.g., Ser179Cys, Tyr191Cys, and Ser204Cys) having been studied much more than others. We review what is currently known about the identified SFD variants in terms of their dimerization, metalloproteinase inhibition, and impact on angiogenesis, with a focus on disparities between reports and areas requiring further study. We als...
Source: Molecular Vision - April 11, 2024 Category: Molecular Biology Authors: Jacob H J Betts Linda Troeberg Source Type: research
