Giant Cell Tumor of Mandible : A Case Report
We present a rare case of giant cell tumor of mandible. Patient was a 33 years old lady who presented with gradually progressive painful swelling in chin. After exclusion of distant metastasis by F-18 FDG PET scan, she underwent en-bloc resection of the tumor with free fibula flap reconstruction. During 6 months of follow up visit patient had no recurrence. (Source: Indian Journal of Otolaryngology and Head and Neck Surgery)
Source: Indian Journal of Otolaryngology and Head and Neck Surgery - December 19, 2023 Category: ENT & OMF Source Type: research
Denosumab and Mortality in a Real ‐World Setting: A Comparative Study
This study examined the association between Dmab and all-cause mortality compared with no treatment in subjects with a fracture and BPs in subjects without a fracture. The study population was from the Sax Institute's 45 and Up Study (n = 267,357), a prospective population-based cohort with questionnaire data linked to hospital admissions (Admitted Patients Data Collection [APDC] data were linked by the Centre for Health Record Linkage), medication records (Pharmaceutical Benefits Scheme [PBS] provided by Services Australia), and stored securely (secure data access was provided through the Sax Institute's Secure Unifie...
Source: Journal of Bone and Mineral Research - December 16, 2023 Category: Orthopaedics Authors: Dunia Alarkawi,
Thach Tran,
Weiwen Chen,
Lyn M March,
Fiona M Blyth,
Robert D Blank,
Dana Bliuc,
Jacqueline R Center Tags: Research Article Source Type: research
Establishment of bone-targeted nano-platform and the study of its combination with 2-deoxy-d-glucose enhanced photodynamic therapy to inhibit bone metastasis
In this study, zoledronic acid (ZOL) demonstrated excellent bone-targeting properties as a bone-targeting ligand. The metal-organic framework (MOF) known as ZIF-90 was modified with ZOL to construct a bone-targeting-based drug delivery system. Chlorin e6 (Ce6) was loaded in the bone-targeted drug delivery system and combined with 2-deoxy-D-glucose (2-DG), which successfully treated bone tumors when enhanced photodynamic therapy was applied. The Ce6@ZIF-PEG-ZOL (Ce6@ZPZ) nanoparticles were observed to have uniform morphology, a particle size of approximately 210 nm, and a potential of approximately -30.4 mV. The results of ...
Source: Journal of the Mechanical Behavior of Biomedical Materials - December 13, 2023 Category: Materials Science Authors: Wanzhen Li Yongqi Yang Jun Wang Ting Ge Shuixia Wan Lin Gui Yugui Tao Ping Song Liangjun Yang Fei Ge Weiwei Zhang Source Type: research
Establishment of bone-targeted nano-platform and the study of its combination with 2-deoxy-d-glucose enhanced photodynamic therapy to inhibit bone metastasis
In this study, zoledronic acid (ZOL) demonstrated excellent bone-targeting properties as a bone-targeting ligand. The metal-organic framework (MOF) known as ZIF-90 was modified with ZOL to construct a bone-targeting-based drug delivery system. Chlorin e6 (Ce6) was loaded in the bone-targeted drug delivery system and combined with 2-deoxy-D-glucose (2-DG), which successfully treated bone tumors when enhanced photodynamic therapy was applied. The Ce6@ZIF-PEG-ZOL (Ce6@ZPZ) nanoparticles were observed to have uniform morphology, a particle size of approximately 210 nm, and a potential of approximately -30.4 mV. The results of ...
Source: Journal of the Mechanical Behavior of Biomedical Materials - December 13, 2023 Category: Materials Science Authors: Wanzhen Li Yongqi Yang Jun Wang Ting Ge Shuixia Wan Lin Gui Yugui Tao Ping Song Liangjun Yang Fei Ge Weiwei Zhang Source Type: research
