Efficacy of switching from teriparatide to zoledronic acid or denosumab on bone mineral density and biochemical markers of bone turnover in older patients with severe osteoporosis: a real-life study
ConclusionsSequential TPT + ZOL therapy is likely to increase bone mineralization at the lumbar level and to stabilize it at the femoral level, similarly to what obtained with the sequential TPT+Dmab. Both ZOL and Dmab are suggested to be effective sequential treatments after TPT. (Source: Endocrine)
Source: Endocrine - August 28, 2023 Category: Endocrinology Source Type: research
Effect of a single dose of zoledronic acid on bone mineral density and trabecular bone score in Indian postmenopausal osteoporotic women with and without type 2 diabetes mellitus – A prospective cohort pilot study
ConclusionThe gain in the LS-BMD was significantly lower in T2DM group compared to non-DM subjects over 12 months after a single IV infusion of 4 mg ZA. The explanation for this could be low bone turnover in diabetes subjects at baseline. (Source: Endocrine)
Source: Endocrine - August 28, 2023 Category: Endocrinology Source Type: research
Drug-related hypophosphatemia: Descriptive study and case/non-case analysis of the French national pharmacovigilance database
Therapie. 2023 Jul 27:S0040-5957(23)00108-7. doi: 10.1016/j.therap.2023.07.007. Online ahead of print.ABSTRACTPhosphorus is an essential element for all living organisms and is involved in various biological pathways. A severe hypophosphatemia can lead to serious complications (acute heart or respiratory failure, rhabdomyolysis, hemolysis…) and increases mortality in patients at risk. Various drugs are known to induce hypophosphatemia through various mechanisms. The aim of this study was to highlight the main drugs associated with hypophosphatemia and to deduce the underlying mechanisms based on a descriptive analysis an...
Source: Therapie - August 27, 2023 Category: Psychiatry & Psychology Authors: Eve-Marie Thillard Paula Sade Joelle Michot Virginie Bres Annie-Pierre Jonville-Bera Source Type: research
Drug-related hypophosphatemia: Descriptive study and case/non-case analysis of the French national pharmacovigilance database
Therapie. 2023 Jul 27:S0040-5957(23)00108-7. doi: 10.1016/j.therap.2023.07.007. Online ahead of print.ABSTRACTPhosphorus is an essential element for all living organisms and is involved in various biological pathways. A severe hypophosphatemia can lead to serious complications (acute heart or respiratory failure, rhabdomyolysis, hemolysis…) and increases mortality in patients at risk. Various drugs are known to induce hypophosphatemia through various mechanisms. The aim of this study was to highlight the main drugs associated with hypophosphatemia and to deduce the underlying mechanisms based on a descriptive analysis an...
Source: Therapie - August 27, 2023 Category: Psychiatry & Psychology Authors: Eve-Marie Thillard Paula Sade Joelle Michot Virginie Bres Annie-Pierre Jonville-Bera Source Type: research
Drug-related hypophosphatemia: Descriptive study and case/non-case analysis of the French national pharmacovigilance database
Therapie. 2023 Jul 27:S0040-5957(23)00108-7. doi: 10.1016/j.therap.2023.07.007. Online ahead of print.ABSTRACTPhosphorus is an essential element for all living organisms and is involved in various biological pathways. A severe hypophosphatemia can lead to serious complications (acute heart or respiratory failure, rhabdomyolysis, hemolysis…) and increases mortality in patients at risk. Various drugs are known to induce hypophosphatemia through various mechanisms. The aim of this study was to highlight the main drugs associated with hypophosphatemia and to deduce the underlying mechanisms based on a descriptive analysis an...
Source: Therapie - August 27, 2023 Category: Psychiatry & Psychology Authors: Eve-Marie Thillard Paula Sade Joelle Michot Virginie Bres Annie-Pierre Jonville-Bera Source Type: research
Drug-related hypophosphatemia: Descriptive study and case/non-case analysis of the French national pharmacovigilance database
Therapie. 2023 Jul 27:S0040-5957(23)00108-7. doi: 10.1016/j.therap.2023.07.007. Online ahead of print.ABSTRACTPhosphorus is an essential element for all living organisms and is involved in various biological pathways. A severe hypophosphatemia can lead to serious complications (acute heart or respiratory failure, rhabdomyolysis, hemolysis…) and increases mortality in patients at risk. Various drugs are known to induce hypophosphatemia through various mechanisms. The aim of this study was to highlight the main drugs associated with hypophosphatemia and to deduce the underlying mechanisms based on a descriptive analysis an...
Source: Therapie - August 27, 2023 Category: Psychiatry & Psychology Authors: Eve-Marie Thillard Paula Sade Joelle Michot Virginie Bres Annie-Pierre Jonville-Bera Source Type: research
Drug-related hypophosphatemia: Descriptive study and case/non-case analysis of the French national pharmacovigilance database
Therapie. 2023 Jul 27:S0040-5957(23)00108-7. doi: 10.1016/j.therap.2023.07.007. Online ahead of print.ABSTRACTPhosphorus is an essential element for all living organisms and is involved in various biological pathways. A severe hypophosphatemia can lead to serious complications (acute heart or respiratory failure, rhabdomyolysis, hemolysis…) and increases mortality in patients at risk. Various drugs are known to induce hypophosphatemia through various mechanisms. The aim of this study was to highlight the main drugs associated with hypophosphatemia and to deduce the underlying mechanisms based on a descriptive analysis an...
Source: Therapie - August 27, 2023 Category: Psychiatry & Psychology Authors: Eve-Marie Thillard Paula Sade Joelle Michot Virginie Bres Annie-Pierre Jonville-Bera Source Type: research
Drug-related hypophosphatemia: Descriptive study and case/non-case analysis of the French national pharmacovigilance database
Therapie. 2023 Jul 27:S0040-5957(23)00108-7. doi: 10.1016/j.therap.2023.07.007. Online ahead of print.ABSTRACTPhosphorus is an essential element for all living organisms and is involved in various biological pathways. A severe hypophosphatemia can lead to serious complications (acute heart or respiratory failure, rhabdomyolysis, hemolysis…) and increases mortality in patients at risk. Various drugs are known to induce hypophosphatemia through various mechanisms. The aim of this study was to highlight the main drugs associated with hypophosphatemia and to deduce the underlying mechanisms based on a descriptive analysis an...
Source: Therapie - August 27, 2023 Category: Psychiatry & Psychology Authors: Eve-Marie Thillard Paula Sade Joelle Michot Virginie Bres Annie-Pierre Jonville-Bera Source Type: research
Drug-related hypophosphatemia: Descriptive study and case/non-case analysis of the French national pharmacovigilance database
Therapie. 2023 Jul 27:S0040-5957(23)00108-7. doi: 10.1016/j.therap.2023.07.007. Online ahead of print.ABSTRACTPhosphorus is an essential element for all living organisms and is involved in various biological pathways. A severe hypophosphatemia can lead to serious complications (acute heart or respiratory failure, rhabdomyolysis, hemolysis…) and increases mortality in patients at risk. Various drugs are known to induce hypophosphatemia through various mechanisms. The aim of this study was to highlight the main drugs associated with hypophosphatemia and to deduce the underlying mechanisms based on a descriptive analysis an...
Source: Therapie - August 27, 2023 Category: Psychiatry & Psychology Authors: Eve-Marie Thillard Paula Sade Joelle Michot Virginie Bres Annie-Pierre Jonville-Bera Source Type: research
Drug-related hypophosphatemia: Descriptive study and case/non-case analysis of the French national pharmacovigilance database
Therapie. 2023 Jul 27:S0040-5957(23)00108-7. doi: 10.1016/j.therap.2023.07.007. Online ahead of print.ABSTRACTPhosphorus is an essential element for all living organisms and is involved in various biological pathways. A severe hypophosphatemia can lead to serious complications (acute heart or respiratory failure, rhabdomyolysis, hemolysis…) and increases mortality in patients at risk. Various drugs are known to induce hypophosphatemia through various mechanisms. The aim of this study was to highlight the main drugs associated with hypophosphatemia and to deduce the underlying mechanisms based on a descriptive analysis an...
Source: Therapie - August 27, 2023 Category: Psychiatry & Psychology Authors: Eve-Marie Thillard Paula Sade Joelle Michot Virginie Bres Annie-Pierre Jonville-Bera Source Type: research
