Preterm Birth Alters the Regional Development and Structural Covariance of Cerebellum at Term-Equivalent Age
In this study, using the structural MR images of 52 preterm infants scanned at term-equivalent age and 312 full-term controls from the Developing Human Connectome Project, we compared volumetric growth, local cerebellum shape development and cerebello-cerebral structural covariance between the two groups. We found that although there was no significant difference in the overall volume measurements between preterm and full-term infants, the shape measurements were different. Compared with the control infants, preterm infants had significantly larger thickness in the vermis and lower thickness in the lateral portions of the ...
Source: Cerebellum - April 6, 2024 Category: Neuroscience Authors: Feifei Xu Yu Wang Wenjun Wang Wenjia Liang Yuchun Tang Shuwei Liu Source Type: research

Preterm Birth Alters the Regional Development and Structural Covariance of Cerebellum at Term-Equivalent Age
In this study, using the structural MR images of 52 preterm infants scanned at term-equivalent age and 312 full-term controls from the Developing Human Connectome Project, we compared volumetric growth, local cerebellum shape development and cerebello-cerebral structural covariance between the two groups. We found that although there was no significant difference in the overall volume measurements between preterm and full-term infants, the shape measurements were different. Compared with the control infants, preterm infants had significantly larger thickness in the vermis and lower thickness in the lateral portions of the ...
Source: Cerebellum - April 6, 2024 Category: Neuroscience Authors: Feifei Xu Yu Wang Wenjun Wang Wenjia Liang Yuchun Tang Shuwei Liu Source Type: research

Preterm Birth Alters the Regional Development and Structural Covariance of Cerebellum at Term-Equivalent Age
In this study, using the structural MR images of 52 preterm infants scanned at term-equivalent age and 312 full-term controls from the Developing Human Connectome Project, we compared volumetric growth, local cerebellum shape development and cerebello-cerebral structural covariance between the two groups. We found that although there was no significant difference in the overall volume measurements between preterm and full-term infants, the shape measurements were different. Compared with the control infants, preterm infants had significantly larger thickness in the vermis and lower thickness in the lateral portions of the ...
Source: The Cerebellum - April 6, 2024 Category: Neurology Source Type: research

Gestational and neonatal outcomes of women with partial Dunnigan lipodystrophy
ConclusionOur data showed a high frequency of fetal complications in women with FPLD2. However, no instances of infertility or prolonged attempts to conceive have been reported, highlighting the significance of employing effective contraception strategies to plan pregnancies at optimal times for managing metabolic comorbidities. (Source: Frontiers in Endocrinology)
Source: Frontiers in Endocrinology - April 3, 2024 Category: Endocrinology Source Type: research

Early HbA1c Levels as a Predictor of Adverse Obstetric Outcomes: A Systematic Review and Meta-Analysis
Conclusions: Women with high early HbA1c levels below the range of diabetes presented an increased risk of pregnancy complications such as macrosomia, LGA, and pre-eclampsia. An early HbA1c threshold of >39 mmol/mol (5.7%) showed the strongest association with pregnancy complications.PMID:38541957 | DOI:10.3390/jcm13061732 (Source: Molecular Medicine)
Source: Molecular Medicine - March 28, 2024 Category: Molecular Biology Authors: Laura Ma ñé Humberto Navarro Juan Pedro-Botet Juan Jos é Chillarón Silvia Ballesta Antonio Pay à Ver ónica Amador Juana Antonia Flores-Le Roux David Benaiges Source Type: research

Early HbA1c Levels as a Predictor of Adverse Obstetric Outcomes: A Systematic Review and Meta-Analysis
Conclusions: Women with high early HbA1c levels below the range of diabetes presented an increased risk of pregnancy complications such as macrosomia, LGA, and pre-eclampsia. An early HbA1c threshold of >39 mmol/mol (5.7%) showed the strongest association with pregnancy complications.PMID:38541957 | DOI:10.3390/jcm13061732 (Source: Molecular Medicine)
Source: Molecular Medicine - March 28, 2024 Category: Molecular Biology Authors: Laura Ma ñé Humberto Navarro Juan Pedro-Botet Juan Jos é Chillarón Silvia Ballesta Antonio Pay à Ver ónica Amador Juana Antonia Flores-Le Roux David Benaiges Source Type: research

In vitro inhibition of uterine contractions using electrospun nanofibers loaded with nifedipine and ML7
CONCLUSIONS: The results indicate that human uterine contractions can be inhibited using calcium channel blocker (nifedipine) and myosin light chain kinase inhibitor (ML7) loaded nanofibers in uterine tissue strips. These results strongly suggested the potential for the development of locally effective and safe controlled drug release systems to prevent premature birth.PMID:38497872 | DOI:10.26355/eurrev_202403_35603 (Source: Pharmacological Reviews)
Source: Pharmacological Reviews - March 18, 2024 Category: Drugs & Pharmacology Authors: Y Karasu M Demeli Ertu ş D Önal B Top çu H Ero ğlu B Pehlivano ğlu Source Type: research

In vitro inhibition of uterine contractions using electrospun nanofibers loaded with nifedipine and ML7
CONCLUSIONS: The results indicate that human uterine contractions can be inhibited using calcium channel blocker (nifedipine) and myosin light chain kinase inhibitor (ML7) loaded nanofibers in uterine tissue strips. These results strongly suggested the potential for the development of locally effective and safe controlled drug release systems to prevent premature birth.PMID:38497872 | DOI:10.26355/eurrev_202403_35603 (Source: European Review for Medical and Pharmacological Sciences)
Source: European Review for Medical and Pharmacological Sciences - March 18, 2024 Category: Drugs & Pharmacology Authors: Y Karasu M Demeli Ertu ş D Önal B Top çu H Ero ğlu B Pehlivano ğlu Source Type: research

In vitro inhibition of uterine contractions using electrospun nanofibers loaded with nifedipine and ML7
CONCLUSIONS: The results indicate that human uterine contractions can be inhibited using calcium channel blocker (nifedipine) and myosin light chain kinase inhibitor (ML7) loaded nanofibers in uterine tissue strips. These results strongly suggested the potential for the development of locally effective and safe controlled drug release systems to prevent premature birth.PMID:38497872 | DOI:10.26355/eurrev_202403_35603 (Source: Pharmacological Reviews)
Source: Pharmacological Reviews - March 18, 2024 Category: Drugs & Pharmacology Authors: Y Karasu M Demeli Ertu ş D Önal B Top çu H Ero ğlu B Pehlivano ğlu Source Type: research

In vitro inhibition of uterine contractions using electrospun nanofibers loaded with nifedipine and ML7
CONCLUSIONS: The results indicate that human uterine contractions can be inhibited using calcium channel blocker (nifedipine) and myosin light chain kinase inhibitor (ML7) loaded nanofibers in uterine tissue strips. These results strongly suggested the potential for the development of locally effective and safe controlled drug release systems to prevent premature birth.PMID:38497872 | DOI:10.26355/eurrev_202403_35603 (Source: European Review for Medical and Pharmacological Sciences)
Source: European Review for Medical and Pharmacological Sciences - March 18, 2024 Category: Drugs & Pharmacology Authors: Y Karasu M Demeli Ertu ş D Önal B Top çu H Ero ğlu B Pehlivano ğlu Source Type: research

In vitro inhibition of uterine contractions using electrospun nanofibers loaded with nifedipine and ML7
CONCLUSIONS: The results indicate that human uterine contractions can be inhibited using calcium channel blocker (nifedipine) and myosin light chain kinase inhibitor (ML7) loaded nanofibers in uterine tissue strips. These results strongly suggested the potential for the development of locally effective and safe controlled drug release systems to prevent premature birth.PMID:38497872 | DOI:10.26355/eurrev_202403_35603 (Source: Pharmacological Reviews)
Source: Pharmacological Reviews - March 18, 2024 Category: Drugs & Pharmacology Authors: Y Karasu M Demeli Ertu ş D Önal B Top çu H Ero ğlu B Pehlivano ğlu Source Type: research

In vitro inhibition of uterine contractions using electrospun nanofibers loaded with nifedipine and ML7
CONCLUSIONS: The results indicate that human uterine contractions can be inhibited using calcium channel blocker (nifedipine) and myosin light chain kinase inhibitor (ML7) loaded nanofibers in uterine tissue strips. These results strongly suggested the potential for the development of locally effective and safe controlled drug release systems to prevent premature birth.PMID:38497872 | DOI:10.26355/eurrev_202403_35603 (Source: European Review for Medical and Pharmacological Sciences)
Source: European Review for Medical and Pharmacological Sciences - March 18, 2024 Category: Drugs & Pharmacology Authors: Y Karasu M Demeli Ertu ş D Önal B Top çu H Ero ğlu B Pehlivano ğlu Source Type: research