In vitro inhibition of uterine contractions using electrospun nanofibers loaded with nifedipine and ML7

CONCLUSIONS: The results indicate that human uterine contractions can be inhibited using calcium channel blocker (nifedipine) and myosin light chain kinase inhibitor (ML7) loaded nanofibers in uterine tissue strips. These results strongly suggested the potential for the development of locally effective and safe controlled drug release systems to prevent premature birth.PMID:38497872 | DOI:10.26355/eurrev_202403_35603

Source: Pharmacological Reviews - March 18, 2024 Category: Drugs & Pharmacology Authors: Y Karasu M Demeli Ertu ş D Önal B Top çu H Ero ğlu B Pehlivano ğlu Source Type: research