Recommended Drugs for Severe Hypertension in Pregnancy Show Similar Efficacy, Safety Recommended Drugs for Severe Hypertension in Pregnancy Show Similar Efficacy, Safety
Nifedipine, hydralazine and labetalol have similar efficacy and negligible differences in their safety profile, and are likely comparable for treating severe hypertension in pregnancy, according to a recent network meta-analysis.Reuters Health Information (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - July 13, 2018 Category: Consumer Health News Tags: Cardiology News Source Type: news

Could blood pressure drugs be the new MALE contraception?
One of the most promising non-hormonal alternatives for a male contraceptive is a 20p pill called nifedipine. Scientists from Harvard University have found the drug can switch off sperm's swimming ability. (Source: the Mail online | Health)
Source: the Mail online | Health - February 20, 2017 Category: Consumer Health News Source Type: news

Adalat CC (Nifedipine) - updated on RxList
(Source: RxList - New and Updated Drug Monographs)
Source: RxList - New and Updated Drug Monographs - February 6, 2017 Category: Drugs & Pharmacology Source Type: news

Fatal acute intoxication of accidentally ingested nifedipine in an infant - A case report - Yamamoto H, Takayasu T, Nosaka M, Kimura A, Ishida Y, Kawaguchi T, Fukami M, Okada M, Kondo T.
A fatal case of acute nifedipine intoxication in a two-year-old boy is presented. The boy accidentally orally ingested an unknown amount of his grandfather's nifedipine (40mg/tablet), mistaking it for a ramune confectionery. Despite intensive medical treat... (Source: SafetyLit)
Source: SafetyLit - January 21, 2017 Category: Global & Universal Tags: Age: Infants and Children Source Type: news

Nifedipine vs Placebo for Treatment of Chronic Chilblains Nifedipine vs Placebo for Treatment of Chronic Chilblains
Should nifedipine be prescribed for chilblains? Is it more effective than placebo?Annals of Family Medicine (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - November 17, 2016 Category: Consumer Health News Tags: Family Medicine/Primary Care Journal Article Source Type: news

nifedipine, Adalat (discontinued brand), Procardia, Afeditab, Nifediac
Title: nifedipine, Adalat (discontinued brand), Procardia, Afeditab, NifediacCategory: MedicationsCreated: 12/31/1997 12:00:00 AMLast Editorial Review: 11/2/2016 12:00:00 AM (Source: MedicineNet Heart General)
Source: MedicineNet Heart General - November 2, 2016 Category: Cardiology Source Type: news

Procardia (Nifedipine) - updated on RxList
(Source: RxList - New and Updated Drug Monographs)
Source: RxList - New and Updated Drug Monographs - September 14, 2016 Category: Drugs & Pharmacology Source Type: news

Nifedipine Might Not Help Chronic Chilblains (FREE)
By Kelly Young Edited by David G. Fairchild, MD, MPH, and Jaye Elizabeth Hefner, MD The calcium-channel blocker nifedipine is not associated with improvements in chilblains, contrary to advice recommending its use, according to a … (Source: Physician's First Watch current issue)
Source: Physician's First Watch current issue - September 12, 2016 Category: Primary Care Source Type: news

Afeditab CR (Nifedipine Extended-Release Tablets) - updated on RxList
(Source: RxList - New and Updated Drug Monographs)
Source: RxList - New and Updated Drug Monographs - February 22, 2016 Category: Drugs & Pharmacology Source Type: news

Procardia (Nifedipine): Contributing Factor to Implant Failure?
Does anyone have any information as to whether Procardia is a contributing factor to implant failure? (Source: Dental Implants Discussed by Experts)
Source: Dental Implants Discussed by Experts - September 25, 2015 Category: Dentistry Authors: osseonews Tags: Dental Implants Q&A failed implant Source Type: news

Pregnancy: Hypertensive Emergency Recommendations UpdatedPregnancy: Hypertensive Emergency Recommendations Updated
Oral nifedipine has been added as a first-line treatment option for preeclampsia, eclampsia. Medscape Medical News (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - January 28, 2015 Category: Consumer Health News Tags: Ob/Gyn & Women ' s Health News Source Type: news

nifedipine, Adalat (discontinued brand), Procardia, Afeditab, Nifediac
Title: nifedipine, Adalat (discontinued brand), Procardia, Afeditab, NifediacCategory: MedicationsCreated: 12/31/1997 12:00:00 AMLast Editorial Review: 12/17/2014 12:00:00 AM (Source: MedicineNet Heart General)
Source: MedicineNet Heart General - December 17, 2014 Category: Cardiology Source Type: news

Jellyfish conquering the world: Weekly Web Review in Toxicology
http://www.youtube.com/watch?v=eyCigZ_bsTM Having just returned from vacation and from the 2013 North American Congress on Clinical Toxicology in Atlanta — where I had the pleasure of meeting and hanging out with such toxicology social media luminaries as @PharmERToxGuy, @DavidJuurlink, @Jldorazio, and @toxic_tweets. Because I’ve been away, I have some catching up to do, and this installment will cover not just toxicology on the web over the last week, but the last month. Jellyfish well on their way to world domination: In his New York Review of Books piece on Lisa-ann Gershwin’s Stung...
Source: The Poison Review - October 9, 2013 Category: Toxicology Authors: Leon Tags: Medical arsenic box jellyfish irukandji isa-ann gershwin pma stung! thallium tianle li Source Type: news

Methylene blue for toxic shock?
This article review the experimental and clinical literature suggesting that methylene blue may have a role in reversing distributive shock (caused by vasodilatation). The two primary causes of distributive shock are anaphylaxis and sepsis. Certain drug overdoses, particularly those associated with dihydropyridine calcium channel blockers (e.g., nifedipine and amlodipine) can also produce shock from vasodilatation. Experimental evidence indicates that the nitric oxide-cyclic guanosine monophosphate pathway is a key factor in producing distributive shock; methylene blue selectively inhibits this pathway.  The...
Source: The Poison Review - October 5, 2013 Category: Toxicology Authors: Leon Tags: Medical amlodipine antidote distributive shock methylene blue toxic shock vasodilatation Source Type: news

Review: Postpartum management of hypertension
Source: BMJ Area: News The British Medical Journal has featured a review on the postpartum management of hypertension. The most common cause of postpartum hypertension is gestational hypertension or pre-eclampsia that persists after delivery.   In terms of medical management, the review states that suggested first line antihypertensive drugs that are safe in breastfeeding mothers include labetalol, nifedipine, and enalapril. (Source: NeLM - Cardiovascular Medicine)
Source: NeLM - Cardiovascular Medicine - February 26, 2013 Category: Cardiology Source Type: news

RCT: Effect of maintenance tocolysis with nifedipine in threatened preterm labour on perinatal outcomes
Source: JAMA Area: News In threatened preterm labour, maintenance tocolysis with nifedipine, after an initial course of tocolysis and corticosteroids for 48 hours, may improve perinatal outcome. The APOSTEL-II (Assessment of Perinatal Outcome with Sustained Tocolysis in Early Labor) RCT evaluated whether maintenance tocolysis with nifedipine reduces adverse perinatal outcomes due to premature birth.   The study was conducted at 11 perinatal units centres in the Netherlands from June 2008 to February 2010 and involved women with threatened preterm labour between 26 weeks (plus 0 days) and 32 weeks (plus 2 days) ge...
Source: NeLM - News - January 3, 2013 Category: Drugs & Pharmacology Source Type: news

Tocolytic Agent No Help for Birth Outcomes (CME/CE)
(MedPage Today) -- For women with threatened preterm labor, maintenance with nifedipine to stop contractions does not improve perinatal outcomes, a randomized trial showed. (Source: MedPage Today OB/GYN)
Source: MedPage Today OB/GYN - January 2, 2013 Category: OBGYN Source Type: news

Maintenance nifedipine tocolysis doesn't improve perinatal outcomes
NEW YORK (Reuters Health) - Maintenance tocolysis with nifedipine after an initial course of tocolytics and corticosteroids did not improve perinatal outcomes relative to placebo in the large Dutch APOSTEL-II trial of women with threatened preterm labor. (Source: Modern Medicine)
Source: Modern Medicine - January 2, 2013 Category: Journals (General) Source Type: news

Nifedipine-Maintained Tocolysis Doesn't Alter Birth OutcomesNifedipine-Maintained Tocolysis Doesn't Alter Birth Outcomes
Maintenance tocolysis with nifedipine beyond 48 hours does not reduce adverse perinatal outcomes, according to a new randomized controlled trial. Medscape Medical News (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - January 1, 2013 Category: Consumer Health News Tags: Ob/Gyn & Women ' s Health News Source Type: news