The Contribution of Bone to Whole Organism Physiology
GeroScience Interest Group
The Trans-NIH GeroScience Interest Group (GSIG), cordially invites you to its spring seminar, featuring Dr. Gerard Karsenty, the Paul A. Marks M.D., Professor and Chair of the Department of Genetics and Development at Columbia University Medical Center, New York City.
Dr. Karsenty's main interest is how organs interact with one another to regulate vertebrates' various physiological functions. His research focuses on bone and, through the use of genetics, he has discovered that this organ, in addition to making bone, has remarkable endocrine functions that include the regulation of insulin secreti...
Source: Videocast - All Events - May 1, 2017 Category: Journals (General) Tags: Upcoming Events Source Type: video
Multifaceted Functions of Mitochondria in Neuronal Synapses
Director's Seminar Series
The Section on Synapse Development and Synaptic Plasticity led by Dr. Zheng Li is interested in the molecular and cellular mechanisms underlying synapse development and synaptic plasticity in normal brains and synaptopathology associated with psychiatric disorders. Our research shows that mitochondria, the vital organelles in eukaryotic cells, not only are essential for the general cell physiology, but also play multifaceted roles in synapses. In hippocampal neurons, the quantify of mitochondria in dendrites determines the density of synapses and dendritic spines. Mitochondria are permeabilized up...
Source: Videocast - All Events - April 17, 2017 Category: Journals (General) Tags: Upcoming Events Source Type: video
The gut microbiome: a master regulator of metabolism
Immunology Interest Group Seminar Series
Humans and many other animals are home to enormous numbers of beneficial bacteria that profoundly influence health. The existence of beneficial resident microorganisms was first recognized in the late 1800's by Louis Pasteur, who founded the field of medical microbiology. However, we ’ ve only recently begun to acquire a molecular understanding of how resident microorganisms contribute to our health. The Hooper lab has spent more than a decade studying how resident bacteria of the gut communicate with our own cells to shape our physiology, our development, and our ability to fight...
Source: Videocast - All Events - March 27, 2017 Category: Journals (General) Tags: Upcoming Events Source Type: video
Unraveling Smell
NIH Director ’ s Wednesday Afternoon Lecture Series
Dr. Linda Buck is a Howard Hughes Medical Institute Investigator, a Full Member of Fred Hutchinson Cancer Research Center, and an Affiliate Professor at the University of Washington. She received a B.S. from the University of Washington and a Ph.D. from the University of Texas Southwestern Medical Center. She was previously Full Professor of Neurobiology at Harvard Medical School. Dr. Buck is a Member of the National Academy of Sciences, the National Academy of Medicine, and the American Academy of Arts of Sciences, a Fellow of the American Association for the Advanceme...
Source: Videocast - All Events - February 27, 2017 Category: Journals (General) Tags: Upcoming Events Source Type: video
Bone Marrow Aging and the PTH Receptor: A Model of Integrative Physiology
Trans-NIH GeroScience Interest Group (GSIG)
Dr. Cliff Rosen is a Senior Scientist and the Director of the Center for Clinical and Translational Research at the Maine Medical Center Research Institute (MMCRI). His laboratory studies the mesenchymal stem cell fate as it relates to the switch between pre-adipocytes and pre-osteoblasts. The focus of these efforts relates to cell autonomous factors such as substrate utilization and bioenergetics of the osteoblast and cell non-autonomous determinants such as parathyroid hormone and sympathetic tone. Dr. Rosen ’ s current projects, supported by the NIH, revolve around the origi...
Source: Videocast - All Events - January 10, 2017 Category: Journals (General) Tags: Upcoming Events Source Type: video
Redox Biology 2016: Redox enzymes and Redox physiology
Redox enzymes and Redox physiologyFor more information go tohttp://ccr.cancer.gov/trainee-resources-courses-workshops-rbAir date: 10/25/2016 4:00:00 PM (Source: Videocast - All Events)
Source: Videocast - All Events - August 30, 2016 Category: Journals (General) Tags: Upcoming Events Source Type: video
Maurice B. Burg Lecture 2016: The Kidney and New Therapies for Diabetes
In the early 20th century Homer Smith demonstrated that glucose was freely filtered by the human kidney, no glucose was lost in the urine, and phlorizin completely blocked glucose reabsorption. Despite the fact that glycosuria is a hallmark of diabetes, a new class of drugs derived from phlorizin have been introduced to lower hyperglycemia in these patients by increasing glycosuria. Dr. Wright will review the kidney physiology and preclinical studies that led to this unexpected new treatment for diabetes.Air date: 10/17/2016 2:00:00 PM (Source: Videocast - All Events)
Source: Videocast - All Events - August 30, 2016 Category: Journals (General) Tags: Upcoming Events Source Type: video
Controlling Global Transcriptome Output with MYC, Supercoils, and Topoisomerase
NCI’s Center for Cancer Research (CCR) Grand Rounds
Dr. Levens received his M.D. and Ph.D. from the University of Chicago. Subsequently, he completed residency training in anatomic pathology at the Laboratory of Pathology, NCI, where he is now the chief of the Gene Regulation Section. Dr. Levens studies fundamental mechanisms of gene regulation, emphasizing the control of MYC function and expression. He and his team showed that MYC amplifies is a universal amplifier of gene expression. This explains much of MYC physiology and pathology, but also defines the need to control MYC levels precisely in real time. The Leven...
Source: Videocast - All Events - April 19, 2016 Category: Journals (General) Tags: Upcoming Events Source Type: video
CC Grand Rounds: (1) Homeostatic Control of Calorie Intake in Humans and its Role in Obesity Treatment and (2) Human Brown Adipose Tissue and Its Role in Treatment of Metabolic Diseases
Presented by: (1) Kevin Hall, PhD, Senior Investigator, Integrative Physiology Section, Laboratory of Biological Modeling, NIDDK, NIH and (2) Aaron M. Cypess, MD, PhD, Investigator and Acting Section Chief, Translational Physiology Section, Diabetes, EndocrinologCategory: Clinical Center Grand RoundsAired date: 01/06/2016 (Source: Videocast - All Events)
Source: Videocast - All Events - January 7, 2016 Category: Journals (General) Tags: Past Events Source Type: video
Three Decades of Neuroscience, Glutamate Receptor Channels
Three Decades of Neuroscience on Glutamate Receptor Channels 9:30 a.m. Welcome and Opening Remarks9:35 a.m. "Who knew NMDA Receptors did this....." Gary Westbrook, M.D., Senior Scientist and Co-Director, Vollum Institute, Oregon Health and Science University10:05 a.m. “Too many Potassium Channels”Bruce Bean, Ph.D., Robert Winthrop Professor of Neurobiology, Department of Neurobiology, Harvard Medical School10:35 a.m. “Glutamate Receptor Pores”James Huettner, Ph.D., Professor, Department of Cell Biology and Physiology, Washington University in St. Louis11:05 a.m. Break11:30 a.m. “NMDA Receptors: Presynaptic, ...
Source: Videocast - All Events - November 13, 2015 Category: Journals (General) Tags: Upcoming Events Source Type: video
Lymphatics as Regulators in Health and Disease (Day 2)
Third Circulation: Lymphatics as Regulators in Health and Disease
A two-day symposium, sponsored by NHLBI, NIAID, and NIDDK in collaboration with other NIH IC's, will bring together lymphatic system researchers and organ experts to explore the function of the lymphatic system in organ physiology and pathology. For more information go to https://palladianpartners.cvent.com/NIHLymphaticConferenceAir date: 9/30/2015 8:00:00 AM (Source: Videocast - All Events)
Source: Videocast - All Events - August 6, 2015 Category: Journals (General) Tags: Upcoming Events Source Type: video
Lymphatics as Regulators in Health and Disease (Day 1)
Third Circulation: Lymphatics as Regulators in Health and Disease
A two-day symposium, sponsored by NHLBI, NIAID, and NIDDK in collaboration with other NIH IC's, will bring together lymphatic system researchers and organ experts to explore the function of the lymphatic system in organ physiology and pathology. For more information go to https://palladianpartners.cvent.com/NIHLymphaticConferenceAir date: 9/29/2015 8:00:00 AM (Source: Videocast - All Events)
Source: Videocast - All Events - August 6, 2015 Category: Journals (General) Tags: Upcoming Events Source Type: video
John Daly Memorial Lecture: TRP Channels and Pain: From Physiology to Atomic Structure
Presented by: David Julius, Ph.D., Professor, Chair Physiology, University of California, School of Medicine, San FranciscoCategory: NIH OnlyAired date: 05/27/2015 (Source: Videocast - All Events)
Source: Videocast - All Events - May 28, 2015 Category: Journals (General) Tags: Past Events Source Type: video
John Daly Memorial Lecture: TRP Channels and Pain: From Physiology to Atomic Structure
Annual John Daly Memorial Lecture
Pungent irritants from pepper, mint and mustard plants have served as powerful for identifying molecules, cells and circuits that contribute to sensation and pain. Dr. Julius has exploited the power of natural products to reveal the molecular mechanisms behind how we feel, sense and touch.
It is quite appropriate for him to deliver the lecture in memory of Dr. John Daly, a noted natural products chemist and pharmacologist in NIDDK. Air date: 5/27/2015 1:00:00 PM (Source: Videocast - All Events)
Source: Videocast - All Events - May 26, 2015 Category: Journals (General) Tags: Upcoming Events Source Type: video
RSV Vaccine Workshop (Day 2)
The purpose of the workshop is to identify obstacles to RSV vaccine development, discuss approaches to alleviating them, and identify gaps in research that could be addressed to enable vaccine development. The meeting will also review the basic science and clinical data that will inform the regulation of products under development including, for example, immune responses to RSV primary infection and reinfection, and the physiology and kinetics of placental antibody transfer as well as discuss progress towards standardization of immunologic agents and assays. Lessons learned from previous clinical trials of RSV vaccines, a...
Source: Videocast - All Events - April 21, 2015 Category: Journals (General) Tags: Upcoming Events Source Type: video
