The gut microbiome: a master regulator of metabolism
Immunology Interest Group Seminar Series Humans and many other animals are home to enormous numbers of beneficial bacteria that profoundly influence health. The existence of beneficial resident microorganisms was first recognized in the late 1800's by Louis Pasteur, who founded the field of medical microbiology. However, we ’ ve only recently begun to acquire a molecular understanding of how resident microorganisms contribute to our health. The Hooper lab has spent more than a decade studying how resident bacteria of the gut communicate with our own cells to shape our physiology, our development, and our ability to fight infectious disease. In my talk, I will discuss our ongoing efforts to unravel this important bacteria-to-human conversation. In particular, I will focus on our recent studies of how resident intestinal bacteria regulate mammalian metabolism. Lora Hooper is a Professor in the Department of Immunology at the University of Texas Southwestern Medical Center, where she holds the Jonathan Uhr Endowed Chair in Immunology. She is also an Investigator of the Howard Hughes Medical Institute. She joined the UT Southwestern faculty in 2003 after completing a post-doctoral fellowship at Washington University and became Chair of the Immunology Department in 2016. During her fellowship training she became interested in interactions between intestinal bacteria and host cells in the mammalian gut. Her research team at UT Southwestern studies interactions between the int...
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