NIH FDA COVID-19 SIG: Metabolic causes and consequences of post-viral syndromes
Maayan Levy, PhD, is an Assistant Professor of Microbiology at the Perelman School of Medicine, University of Pennsylvania. Her research investigates the fascinating question of how metabolites derived from diet and from the microbiome play a pivotal role in regulating various aspects of host physiology. Moreover, she explores the potential therapeutic applications of these metabolites. Maayan completed her doctoral training at the Weizmann Institute of Science. During her PhD studies, she focused on crucial questions concerning the stability of the intestinal microbiome and made significant discoveries related to microbio...
Source: Videocast - All Events - March 27, 2024 Category: General Medicine Tags: Upcoming Events Source Type: video
Microbiome, metabolites and mucosal immunity
Dr. Kathy McCoy is a Professor in the Department of Physiology and Pharmacology, Cumming School of Medicine, member of the Snyder Institute, Scientific Director of the International Microbiome Center, and holds the Killam Memorial Chair at the University of Calgary, Canada. Her research group uses germ-free and gnotobiotic models to investigate the cellular and molecular mechanisms by which the microbiome regulates host immunity and physiology. She is particularly interested in the dynamic interplay between the gut microbiota and the innate and adaptive immune systems. Her research aims to understand how exposure to intest...
Source: Videocast - All Events - February 16, 2024 Category: General Medicine Tags: Upcoming Events Source Type: video
Combining human genetics with physiology to understand the mechanisms of persistent pain
This seminar is part of the NIH Neuroscience Seminar Series supported by the Scientific Directors of every Institute or Center that has Neuroscience Labs at the NIH.Air date: 1/22/2024 12:00:00 PM (Source: Videocast - All Events)
Source: Videocast - All Events - November 15, 2023 Category: General Medicine Tags: Upcoming Events Source Type: video
Designing Nanoparticles to Probe and Cross Biological Barriers to Immunotherapy
The Mucosal Associated Immune System Engineering and Lymphatics (MAISEL) Lab ’ s research integrates nanotechnology, materials science, and tissue engineering with physiology, medicine, and immunology to probe lymphatics and extracellular barriers via novel ex vivo and in vitro models and nanoparticles. We are particularly focused on studying mucosal barriers to the therapeutic path from the mucosal lumen to the downstream lymph nodes and integrating the newly created knowledge to design immune modulatory therapeutic interventions. We have made significant progress in understanding how nanoparticle material properties li...
Source: Videocast - All Events - November 14, 2023 Category: General Medicine Tags: Upcoming Events Source Type: video
Gut-Brain Circuitries and the Physiology of Reward
This is the November 20, 2023 Seminar as part of the NIH Neuroscience Seminar Series.For more information go tohttps://research.ninds.nih.gov/seminars-events/neuroscience-seminar-seriesAir date: 11/20/2023 12:00:00 PM (Source: Videocast - All Events)
Source: Videocast - All Events - October 4, 2023 Category: General Medicine Tags: Upcoming Events Source Type: video
CRISPR-based Single cell approaches for mapping gene function and tumor evolution
Jonathan Weissman investigates how proteins fold into their correct shape and how misfolding impacts disease and normal physiology, while building innovative tools for exploring the organizational principles of biological systems.For more information go tohttps://oir.nih.gov/walsAir date: 6/5/2024 2:00:00 PM (Source: Videocast - All Events)
Source: Videocast - All Events - August 23, 2023 Category: General Medicine Tags: Upcoming Events Source Type: video
The neurobiology and evolution of vocal learning and spoken language
This lecture, established in 2011, recognizes Marshall Nirenberg for his work to decipher the genetic code, which resulted in his receiving the 1968 Nobel Prize in Physiology or Medicine. Nirenberg ’ s research career at the NIH spanned more than 50 years, and his research also focused on neuroscience, neural development, and the homeobox genes. The Nirenberg lecture recognizes outstanding contributions to genetics and molecular biology.
The focus of Jarvis' research is the vocal learning capabilities in birds and how they learn to mimic sounds.His research with songbirds is being used to show the evolution of human l...
Source: Videocast - All Events - August 1, 2023 Category: General Medicine Tags: Upcoming Events Source Type: video
Not Your Father ’ s Heart Disease: The 'Herstory' and the NHLBI WISE
The research of C. Noel Bairey Merz, MD, focuses on heart disease in women, preventive cardiology, coronary physiology/pathophysiology and advanced cardiac imaging, as well as alternative and complementary medicine approaches to heart disease.For more information go tohttps://oir.nih.gov/walsAir date: 4/24/2024 2:00:00 PM (Source: Videocast - All Events)
Source: Videocast - All Events - July 19, 2023 Category: General Medicine Tags: Upcoming Events Source Type: video
The Phase of Fat: Mechanisms and Physiology of Lipid Storage
Speaker Tobias Walther, Ph.D., is an HHMI Investigator and a Program Chair at Sloan Kettering Institute. Walther is interested in the mechanisms that underlie lipid storage in cell membranes and energy metabolism. Walther and his team study how lipids are formed and stored and how these processes contribute to obesity and metabolic disease. They apply a wide range of interdisciplinary approaches, from biophysics and biochemistry to proteomics and lipidomics, to discover global insights into the regulation of lipid metabolism. Once they have identified important regulatory circuits, they use methodologies such as live cell ...
Source: Videocast - All Events - June 26, 2023 Category: General Medicine Tags: Upcoming Events Source Type: video
IIG Seminar - Immune calibration of neuroendocrine homeostasis
It has become increasingly evident that interactions between the enteric nervous system (ENS) and the immune system play important roles to modulate inflammatory responses. Such interaction is particularly critical in the context of the intestinal microenvironment given the unique properties of this organ: intestinal tissue is continuously exposed to numerous microbial and food-derived antigens. In order to deal with these stimuli yet maintain normal physiology and function, intestinal responses are tightly regulated by actions of both the immune and nervous systems, which co-localize in the intestinal microenvironment wit...
Source: Videocast - All Events - June 5, 2023 Category: General Medicine Tags: Upcoming Events Source Type: video
NIH Director's Seminar Series: How the fat gets on proteins – structure and mechanism of enzymes that catalyze protein palmitoylation
Posttranslational modification of proteins by attachment of lipids touches almost all areas of cellular physiology. One of the major areas of interest in our lab are integral membrane enzymes that catalyze protein lipidation. The most widely prevalent form of protein lipidation is protein S-acylation or protein palmitoylation whereby membrane proximal cysteines are modified by fatty acids through a thioester linkage. Protein palmitoylation, owing to its inherent lability through the action of cellular thioesterases, offers a unique, potentially dynamic form of protein lipidation. There are 23 members of the DHHC family of ...
Source: Videocast - All Events - May 8, 2023 Category: General Medicine Tags: Upcoming Events Source Type: video
Nobel Prizes and the Emerging Gene Concept
Join us for our next talk in the Office of NIH History lecture series. Erling Norrby, M.D., Ph.D., of the Royal Swedish Academy of Sciences will speak about the changing concept of the gene through the lens of Nobel Prizes awarded in the past century. Dr. Norrby is former chair at the Karolinska Institute in Stockholm, where he served as dean of the Faculty of Medicine and was involved in the selection process for the Nobel Prize in Physiology or Medicine for 20 years. After leaving the Institute, he became Permanent Secretary of the Royal Swedish Academy of Sciences. In this role, he had overriding responsibility for the ...
Source: Videocast - All Events - February 10, 2023 Category: General Medicine Tags: Upcoming Events Source Type: video
Biomedical History Lecture with Dr. Erling Norrby
A global leader on immunology& vaccines, Dr. Norrby is the former Dean of the Faculty of Medicine at the Karolinska Institute, Stockholm, Sweden. There Norrby was instrumental in the selection process for Nobel Prize recipients in the Physiology of Medicine; and later served as permanent secretary of the Royal Swedish Academy of Sciences, and a board member of the Nobel Foundation. At present, Dr. Norrby is with the Center for History of Science at The Royal Swedish Academy of Sciences; and serves as the Vice Chair of the Board of the J. Craig Venter Institute in La Jolla, California.For more information go tohttps://histo...
Source: Videocast - All Events - February 7, 2023 Category: General Medicine Tags: Upcoming Events Source Type: video
IIG: The diversity of neutrophils
Dr. Hidalgo is interested in the cellular and molecular mechanisms by which innate immune cells and their hematopoietic precursors contribute to organismal physiology and pathology. As a postdoctoral trainee he developed and used live imaging modalities to study acute inflammatory disease and discovered the receptors that mediate early neutrophil recruitment, and the signals that cause acute vascular injury. As an independent researcher at CNIC (Spain), his laboratory further developed tools to study thrombo-inflammation and the dramatic consequences in several organs, including the lung, brain and heart. The Hidalgo lab d...
Source: Videocast - All Events - January 27, 2023 Category: General Medicine Tags: Upcoming Events Source Type: video
The diversity of neutrophils.
Dr. Hidalgo is interested in the cellular and molecular mechanisms by which innate immune cells and their hematopoietic precursors contribute to organismal physiology and pathology. As a postdoctoral trainee he developed and used live imaging modalities to study acute inflammatory disease and discovered the receptors that mediate early neutrophil recruitment, and the signals that cause acute vascular injury. As an independent researcher at CNIC (Spain), his laboratory further developed tools to study thrombo-inflammation and the dramatic consequences in several organs, including the lung, brain and heart. The Hidalgo lab d...
Source: Videocast - All Events - January 10, 2023 Category: General Medicine Tags: Upcoming Events Source Type: video
