Does UK Entry-Level Physiotherapy Education Prepare Graduates for a Future in Pediatric Clinical Practice? A Mixed-Methods Study
CONCLUSIONS: Respondents reported they were not well prepared for pediatric clinical practice. Some entry-level programs did not include any pediatric teaching throughout the entirety of the course.PMID:38644765 | DOI:10.1080/01942638.2024.2338934 (Source: Health Physics)
Source: Health Physics - April 22, 2024 Category: Physics Authors: Paul Chesterton Jennifer Chesterton Source Type: research
Diabetes is associated with longitudinal declined physical performance measures in persons with or at risk of knee osteoarthritis: data from the osteoarthritis initiative
CONCLUSIONS: DM was associated with negative impact on Gait Speed and Repeated Chair Stand Test time in individuals with or at risk of knee OA. Individuals with knee OA and diabetes who exhibit declining physical performance measures are at risk of functional dependence, reduced quality of life, and complex rehabilitation requirements.PMID:38647532 | DOI:10.23736/S1973-9087.24.08034-1 (Source: Health Physics)
Source: Health Physics - April 22, 2024 Category: Physics Authors: Aqeel M Alenazi Bader A Alqahtani Source Type: research
Phantom and clinical evaluation of the Bayesian penalised likelihood reconstruction algorithm Q.Clear without PSF correction in amyloid PET images
CONCLUSION: Gibbs artefacts disappeared from phantom images using the BPL without PSF correction. Visual and quantitative evaluation of [18F]flutemetamol imaging was independent of the reconstruction method. The BPL without PSF correction could be the standard reconstruction method for amyloid PET imaging, despite being qualitatively inferior to BPL with PSF correction for [18F]flutemetamol amyloid PET imaging.PMID:38647924 | PMC:PMC11035535 | DOI:10.1186/s40658-024-00641-3 (Source: Health Physics)
Source: Health Physics - April 22, 2024 Category: Physics Authors: Kei Wagatsuma Muneyuki Sakata Kenta Miwa Yumi Hamano Hirofumi Kawakami Yuto Kamitaka Tensho Yamao Noriaki Miyaji Kenji Ishibashi Tetsuro Tago Jun Toyohara Kenji Ishii Source Type: research
AAPM Task Group 334: A guidance document to using radiotherapy immobilization devices and accessories in an MR environment
Med Phys. 2024 Apr 22. doi: 10.1002/mp.17061. Online ahead of print.ABSTRACTUse of magnetic resonance (MR) imaging in radiation therapy has increased substantially in recent years as more radiotherapy centers are having MR simulators installed, requesting more time on clinical diagnostic MR systems, or even treating with combination MR linear accelerator (MR-linac) systems. With this increased use, to ensure the most accurate integration of images into radiotherapy (RT), RT immobilization devices and accessories must be able to be used safely in the MR environment and produce minimal perturbations. The determination of the...
Source: Health Physics - April 22, 2024 Category: Physics Authors: Maritza A Hobson Yanle Hu Barrett Caldwell Gil'ad N Cohen Carri Glide-Hurst Long Huang Paul D Jackson Sunyoung Jang Ulrich Langner Hannah J Lee Ives R Levesque Sreeram Narayanan Justin C Park John Steffen Q Jackie Wu Yong Zhou Source Type: research
Nutrition and Food Security among Veterans: Operationalizing 'Nutritional Functioning'
CONCLUSIONS: Nutritional functioning (food background, nutrition knowledge, meal aptitude, resource navigation, and navigation to/of food spaces) among injured veterans is complex, and shaped by multiple physical, psychosocial, economic, and cultural factors.PMID:38649010 | DOI:10.1016/j.apmr.2024.04.006 (Source: Health Physics)
Source: Health Physics - April 22, 2024 Category: Physics Authors: Diana P Brostow Alexandra A Smith Nazanin H Bahraini Karen Besterman-Dahan Jeri E Forster Lisa A Brenner Source Type: research
Lifestyle behaviors and risk of cardiovascular disease and prognosis among individuals with cardiovascular disease: a systematic review and meta-analysis of 71 prospective cohort studies
CONCLUSIONS: Adopting healthy LBs is associated with substantial risk reduction in CVD, CVD mortality, and adverse outcomes among individuals diagnosed with CVD. Rather than focusing solely on individual healthy LB, it is advisable to advocate for the adoption of multiple LBs for the prevention and management of CVD.TRIAL REGISTRATION: PROSPERO: CRD42023431731.PMID:38650004 | PMC:PMC11036700 | DOI:10.1186/s12966-024-01586-7 (Source: Health Physics)
Source: Health Physics - April 22, 2024 Category: Physics Authors: Jian Wu Yifei Feng Yuanyuan Zhao Zhiping Guo Rongmei Liu Xin Zeng Fan Yang Bei Liu Jianqing Gu Clifford Silver Tarimo Weihao Shao Xinghong Guo Quanman Li Lipei Zhao Mingze Ma Zhanlei Shen Qiuping Zhao Yudong Miao Source Type: research
A scan-specific quality control acquisition for clinical whole-body (WB) MRI protocols
Phys Med Biol. 2024 Apr 22. doi: 10.1088/1361-6560/ad4195. Online ahead of print.ABSTRACTImage quality in whole-body MRI (WB-MRI) may be degraded by faulty radiofrequency (RF) coil elements or mispositioning of the coil arrays. Phantom-based quality control (QC) is used to identify broken RF coil elements but the frequency of these acquisitions is limited by scanner and staff availability. This work aimed to develop a scan-specific QC acquisition and processing pipeline to detect broken RF coil elements, which is sufficiently rapid to be added to the clinical WB-MRI protocol. The purpose of this is to improve the quality o...
Source: Physics in Medicine and Biology - April 22, 2024 Category: Physics Authors: Sam Keaveney Georgina Hopkinson Julia E Markus Andrew N Priest Erica Scurr Julie Hughes Scott Robertson Simon J Doran David J Collins Christina Messiou Dow-Mu Koh Jessica M Winfield Source Type: research
Patient-specific temperature distribution prediction in laser interstitial thermal therapy: single-irradiation data-driven method
Phys Med Biol. 2024 Apr 22. doi: 10.1088/1361-6560/ad4194. Online ahead of print.ABSTRACTLaser interstitial thermal therapy (LITT) has been popular for treating brain tumours and epilepsy. The strict control of tissue thermal damage extent is crucial for LITT. Temperature prediction is useful for predicting thermal damage extent. Accurately predicting in vivo brain tissue temperature is challenging due to the temperature dependence and the individual variations in tissue properties. Considering these factors is essential for improving the temperature prediction accuracy.OBJECTIVE: To present a method for predicting patient...
Source: Physics in Medicine and Biology - April 22, 2024 Category: Physics Authors: Tingting Gao Libin Liang Hui Ding Guangzhi Wang Source Type: research
TIST-Net: style transfer in dynamic contrast enhanced MRI using spatial and temporal information
In this study, our objective is to develop a style transfer method that incorporates spatio-temporal information to either add or remove contrast enhancement from an existing image.
 
We propose a Temporal Image-to-Image Style Transfer Network (TIST-Net), consisting of an auto-encoder combined with convolutional long short-term memory (LSTM) networks. This enables disentanglement of the content and style latent spaces of the time series data, using spatio-temporal information to learn and predict key structures . To generate new images , we use deformable and adaptive convolutions which allow fine grained c...
Source: Physics in Medicine and Biology - April 22, 2024 Category: Physics Authors: Adam George Tattersall Keith A Goatman Lucy E Kershaw Scott I K Semple Sonia Dahdouh Source Type: research
Spatially fractionated radiation therapy: a critical review on current status of clinical and preclinical studies and knowledge gaps
Phys Med Biol. 2024 Apr 22. doi: 10.1088/1361-6560/ad4192. Online ahead of print.ABSTRACTSpatially fractionated radiation therapy (SFRT) is a therapeutic approach with the potential to disrupt the classical paradigms of conventional radiation therapy. The high spatial dose modulation in SFRT activates distinct radiobiological mechanisms which lead to a remarkable increase in normal tissue tolerances. Several decades of clinical use and numerous preclinical experiments suggest that SFRT has the potential to increase the therapeutic index, especially in bulky and radioresistant tumors. To unleash the full potential of SFRT a...
Source: Physics in Medicine and Biology - April 22, 2024 Category: Physics Authors: Yolanda Prezado Michael Grams Emmanuel Jouglar Immaculada Martinez-Rovira Ramon Ortiz Joao Seco Sha Chang Source Type: research
Task-based automatic keV selection: leveraging routine virtual monoenergetic imaging for dose reduction on clinical photon-counting detector CT
Phys Med Biol. 2024 Apr 22. doi: 10.1088/1361-6560/ad41b3. Online ahead of print.ABSTRACTPhoton-counting detector (PCD) CT enables routine virtual-monoenergetic image (VMI) reconstruction. We evaluated the performance of an automatic VMI energy level (keV) selection tool on a clinical PCD-CT system in comparison to an automatic tube potential (kV) selection tool from an energy-integrating-detector (EID) CT system from the same manufacturer. 
Approach: Four torso-shaped phantoms (20-50 cm width) containing iodine (2, 5, and 10-mg/cc) and calcium (100 mg/cc) were scanned on PCD-CT and EID-CT. Dose optimization techni...
Source: Physics in Medicine and Biology - April 22, 2024 Category: Physics Authors: Kishore Rajendran Michael Bruesewitz Joseph Swicklik Andrea Ferrero Jamison Thorne Lifeng Yu Cynthia H McCollough Shuai Leng Source Type: research
Pulse-echo ultrasound attenuation tomography
We present the first fully two-dimensional attenuation imaging technique developed for pulse-echo ultrasound systems. Unlike state-of-the-art techniques, which use line-by-line acquisitions, our method uses steered emissions to constrain attenuation values at each location with multiple crossing wave paths, essential to resolve the spatial variations of this tissue property.Approach.At every location, we compute normalized cross-correlations between the beamformed images that are obtained from emissions at different steering angles. We demonstrate that their log-amplitudes provide the changes between attenuation-induced am...
Source: Physics in Medicine and Biology - April 22, 2024 Category: Physics Authors: Naiara Korta Martiartu Parisa Salemi Yolgunlu Martin Frenz Michael Jaeger Source Type: research
Breast density quantification in dual-energy mammography using virtual anthropomorphic phantoms
CONCLUSIONS: Our results in virtual phantoms indicate that the material decomposition method can produce accurate VBD measurements if the presence of a third material (skin) is considered. The results from our proof of concept showed agreement between MRI and dual-energy mammography VBD. Assessment of VBD using dual-energy images could provide complementary information in dual-energy mammography and tomosynthesis examinations.PMID:38648734 | DOI:10.1002/acm2.14360 (Source: Journal of Applied Clinical Medical Physics)
Source: Journal of Applied Clinical Medical Physics - April 22, 2024 Category: Physics Authors: Gustavo Pacheco Jorge Patricio Castillo-Lopez Yolanda Villase ñor-Navarro Mar ía-Ester Brandan Source Type: research
Site-directed mutagenesis at the Glu78 in Ec-NhaA transporter impacting ion exchange: a biophysical study
In this study, we have explored the role of Glu78 in the regulation of pH by Ec-NhaA. Although we have created various mutants, E78C has shown a considerable effect on the stoichiometry of NhaA and presented comparable phenotypes. The ITC experiment has shown the binding of ~ 5 protons in response to the transport of one lithium ion. The phenotype analysis on selective medium showed a significant expression compared to WT Ec-NhaA. This represents the importance of Glu78 in transporting the H+ across the membrane where a single mutation with Cys amino acid alters the number of H+ significantly maintaining the activity of th...
Source: European Biophysics Journal : EBJ - April 22, 2024 Category: Physics Authors: Anuradha Yadav Dinesh Kumar Manish Dwivedi Source Type: research
The effect of ionic redistributions on the microwave dielectric response of cytosol water upon glucose uptake
We present some insights into the MD response of cytosol water when exposed to Ca2+ in the absence of D-glucose. The findings from this study confirm that ion-induced alterations in bound/bulk water balance do not affect the MD response of cytosol water during glucose uptake.PMID:38647542 | DOI:10.1007/s00249-024-01708-w (Source: European Biophysics Journal : EBJ)
Source: European Biophysics Journal : EBJ - April 22, 2024 Category: Physics Authors: Cindy Galindo Leonid Livshits Lama Tarabeih Gregory Barshtein Sharon Einav Yuri Feldman Source Type: research
