Administration of the GSK Respiratory Syncytial Virus Vaccine to Pregnant Persons in Error
Obstet Gynecol. 2024 Feb 23. doi: 10.1097/AOG.0000000000005551. Online ahead of print.ABSTRACTThe GSK and Pfizer respiratory syncytial virus (RSV) vaccines are both indicated for adults aged 60 years and older, but only the Pfizer product is approved for use in pregnancy to prevent RSV-associated lower respiratory tract disease in infants aged younger than 6 months. To assess for vaccine administration errors (ie, administration of the GSK RSV vaccine to pregnant persons) VAERS (Vaccine Adverse Event Reporting System), a U.S. passive reporting system, was searched for the time period from August 2023 to January 2024. A tot...
Source: Obstetrics and Gynecology - February 23, 2024 Category: OBGYN Authors: Pedro L Moro Ruth Gallego Anne Scheffey Katherine E Fleming-Dutra Elisha Hall Bicheng Zhang Paige Marquez Jefferson M Jones Narayan Nair Karen R Broder Source Type: research
Etrasimod: First Approval
This article summarises the milestones in the development of etrasimod leading to this first approval for the treatment of ulcer ative colitis in adults. (Source: Drugs)
Source: Drugs - February 23, 2024 Category: Drugs & Pharmacology Source Type: research
A Different Perspective of COVID-19 Pandemic: Efficacy and Safety of mRNA Vaccines in Immunocompetent and Immunocompromised Individuals (Part 3)
Exp Clin Transplant. 2024 Jan;22(Suppl 2):33-62. doi: 10.6002/ect.2023.0132.ABSTRACTShortly after the declaration of the pandemic, several anti-SARS-CoV-2 vaccines entered phase 3 clinical trials. One year later, Pfizer-BioNTech and Moderna published their initial trial results, encompassing a 2-month follow-up. The studies were only designed to test whether the vaccines were effective and safe on the short-term.The vaccine's efficacy in the 2 trials was defined as relative risk reduction instead of absolute risk reduction, a more accurate determinant of vaccine effectiveness in the real world. These studies were not desig...
Source: Experimental and Clinical Transplantation : official journal of the Middle East Society for Organ Transplantation - February 22, 2024 Category: Transplant Surgery Authors: Antoine Barbari Source Type: research
A Different Perspective on the COVID-19 Pandemic: Origin of the Outbreak (Part 1)
Exp Clin Transplant. 2024 Jan;22(Suppl 2):1-14. doi: 10.6002/ect.2023.0074.ABSTRACTIn December 2019, an outbreak caused by novel coronavirus 2019 (COVID-19) started in Wuhan, China. After extensive speculation about a causative agent, a novel betacoronavirus, in the same family as SARS-CoV and MERS-CoV, was identified via next-generation sequencing from samples received from several pneumonia patients. Ribonucleic acid extracted from the patient's bronchoalveolar lavage fluid was used as a template to clone and sequence the genome of SARS-CoV-2. Shortly after, the World Health Organization announced a worldwide pandemic. H...
Source: Experimental and Clinical Transplantation : official journal of the Middle East Society for Organ Transplantation - February 22, 2024 Category: Transplant Surgery Authors: Antoine Barbari Source Type: research
Mortality risk after COVID-19 vaccination: A self-controlled case series study
CONCLUSION: Using a modified SCCS design and adjusting for temporal trends, no-increased risk was found for non-COVID-19 mortality, all-cause mortality, and four cardiac-related death outcomes among recipients of the three COVID-19 vaccines used in the US.PMID:38388239 | DOI:10.1016/j.vaccine.2024.02.032 (Source: Vaccine)
Source: Vaccine - February 22, 2024 Category: Allergy & Immunology Authors: Stanley Xu Lina S Sy Vennis Hong Paddy Farrington Sungching C Glenn Denison S Ryan Abraelle M Shirley Bruno J Lewin Hung-Fu Tseng Gabriela Vazquez-Benitez Jason M Glanz Bruce Fireman David L McClure Laura P Hurley Onchee Yu Michael Wernecke Ning Smith Eri Source Type: research
A Different Perspective of COVID-19 Pandemic: Efficacy and Safety of mRNA Vaccines in Immunocompetent and Immunocompromised Individuals (Part 3)
Exp Clin Transplant. 2024 Jan;22(Suppl 2):33-62. doi: 10.6002/ect.2023.0132.ABSTRACTShortly after the declaration of the pandemic, several anti-SARS-CoV-2 vaccines entered phase 3 clinical trials. One year later, Pfizer-BioNTech and Moderna published their initial trial results, encompassing a 2-month follow-up. The studies were only designed to test whether the vaccines were effective and safe on the short-term.The vaccine's efficacy in the 2 trials was defined as relative risk reduction instead of absolute risk reduction, a more accurate determinant of vaccine effectiveness in the real world. These studies were not desig...
Source: Experimental and Clinical Transplantation : official journal of the Middle East Society for Organ Transplantation - February 22, 2024 Category: Transplant Surgery Authors: Antoine Barbari Source Type: research
A Different Perspective on the COVID-19 Pandemic: Origin of the Outbreak (Part 1)
Exp Clin Transplant. 2024 Jan;22(Suppl 2):1-14. doi: 10.6002/ect.2023.0074.ABSTRACTIn December 2019, an outbreak caused by novel coronavirus 2019 (COVID-19) started in Wuhan, China. After extensive speculation about a causative agent, a novel betacoronavirus, in the same family as SARS-CoV and MERS-CoV, was identified via next-generation sequencing from samples received from several pneumonia patients. Ribonucleic acid extracted from the patient's bronchoalveolar lavage fluid was used as a template to clone and sequence the genome of SARS-CoV-2. Shortly after, the World Health Organization announced a worldwide pandemic. H...
Source: Experimental and Clinical Transplantation : official journal of the Middle East Society for Organ Transplantation - February 22, 2024 Category: Transplant Surgery Authors: Antoine Barbari Source Type: research
Mortality risk after COVID-19 vaccination: A self-controlled case series study
CONCLUSION: Using a modified SCCS design and adjusting for temporal trends, no-increased risk was found for non-COVID-19 mortality, all-cause mortality, and four cardiac-related death outcomes among recipients of the three COVID-19 vaccines used in the US.PMID:38388239 | DOI:10.1016/j.vaccine.2024.02.032 (Source: Vaccine)
Source: Vaccine - February 22, 2024 Category: Allergy & Immunology Authors: Stanley Xu Lina S Sy Vennis Hong Paddy Farrington Sungching C Glenn Denison S Ryan Abraelle M Shirley Bruno J Lewin Hung-Fu Tseng Gabriela Vazquez-Benitez Jason M Glanz Bruce Fireman David L McClure Laura P Hurley Onchee Yu Michael Wernecke Ning Smith Eri Source Type: research
A Different Perspective of COVID-19 Pandemic: Efficacy and Safety of mRNA Vaccines in Immunocompetent and Immunocompromised Individuals (Part 3)
Exp Clin Transplant. 2024 Jan;22(Suppl 2):33-62. doi: 10.6002/ect.2023.0132.ABSTRACTShortly after the declaration of the pandemic, several anti-SARS-CoV-2 vaccines entered phase 3 clinical trials. One year later, Pfizer-BioNTech and Moderna published their initial trial results, encompassing a 2-month follow-up. The studies were only designed to test whether the vaccines were effective and safe on the short-term.The vaccine's efficacy in the 2 trials was defined as relative risk reduction instead of absolute risk reduction, a more accurate determinant of vaccine effectiveness in the real world. These studies were not desig...
Source: Experimental and Clinical Transplantation : official journal of the Middle East Society for Organ Transplantation - February 22, 2024 Category: Transplant Surgery Authors: Antoine Barbari Source Type: research
A Different Perspective on the COVID-19 Pandemic: Origin of the Outbreak (Part 1)
Exp Clin Transplant. 2024 Jan;22(Suppl 2):1-14. doi: 10.6002/ect.2023.0074.ABSTRACTIn December 2019, an outbreak caused by novel coronavirus 2019 (COVID-19) started in Wuhan, China. After extensive speculation about a causative agent, a novel betacoronavirus, in the same family as SARS-CoV and MERS-CoV, was identified via next-generation sequencing from samples received from several pneumonia patients. Ribonucleic acid extracted from the patient's bronchoalveolar lavage fluid was used as a template to clone and sequence the genome of SARS-CoV-2. Shortly after, the World Health Organization announced a worldwide pandemic. H...
Source: Experimental and Clinical Transplantation : official journal of the Middle East Society for Organ Transplantation - February 22, 2024 Category: Transplant Surgery Authors: Antoine Barbari Source Type: research
A Different Perspective of COVID-19 Pandemic: Efficacy and Safety of mRNA Vaccines in Immunocompetent and Immunocompromised Individuals (Part 3)
Exp Clin Transplant. 2024 Jan;22(Suppl 2):33-62. doi: 10.6002/ect.2023.0132.ABSTRACTShortly after the declaration of the pandemic, several anti-SARS-CoV-2 vaccines entered phase 3 clinical trials. One year later, Pfizer-BioNTech and Moderna published their initial trial results, encompassing a 2-month follow-up. The studies were only designed to test whether the vaccines were effective and safe on the short-term.The vaccine's efficacy in the 2 trials was defined as relative risk reduction instead of absolute risk reduction, a more accurate determinant of vaccine effectiveness in the real world. These studies were not desig...
Source: Experimental and Clinical Transplantation : official journal of the Middle East Society for Organ Transplantation - February 22, 2024 Category: Transplant Surgery Authors: Antoine Barbari Source Type: research
A Different Perspective on the COVID-19 Pandemic: Origin of the Outbreak (Part 1)
Exp Clin Transplant. 2024 Jan;22(Suppl 2):1-14. doi: 10.6002/ect.2023.0074.ABSTRACTIn December 2019, an outbreak caused by novel coronavirus 2019 (COVID-19) started in Wuhan, China. After extensive speculation about a causative agent, a novel betacoronavirus, in the same family as SARS-CoV and MERS-CoV, was identified via next-generation sequencing from samples received from several pneumonia patients. Ribonucleic acid extracted from the patient's bronchoalveolar lavage fluid was used as a template to clone and sequence the genome of SARS-CoV-2. Shortly after, the World Health Organization announced a worldwide pandemic. H...
Source: Experimental and Clinical Transplantation : official journal of the Middle East Society for Organ Transplantation - February 22, 2024 Category: Transplant Surgery Authors: Antoine Barbari Source Type: research
A Different Perspective of COVID-19 Pandemic: Efficacy and Safety of mRNA Vaccines in Immunocompetent and Immunocompromised Individuals (Part 3)
Exp Clin Transplant. 2024 Jan;22(Suppl 2):33-62. doi: 10.6002/ect.2023.0132.ABSTRACTShortly after the declaration of the pandemic, several anti-SARS-CoV-2 vaccines entered phase 3 clinical trials. One year later, Pfizer-BioNTech and Moderna published their initial trial results, encompassing a 2-month follow-up. The studies were only designed to test whether the vaccines were effective and safe on the short-term.The vaccine's efficacy in the 2 trials was defined as relative risk reduction instead of absolute risk reduction, a more accurate determinant of vaccine effectiveness in the real world. These studies were not desig...
Source: Experimental and Clinical Transplantation : official journal of the Middle East Society for Organ Transplantation - February 22, 2024 Category: Transplant Surgery Authors: Antoine Barbari Source Type: research
A Different Perspective on the COVID-19 Pandemic: Origin of the Outbreak (Part 1)
Exp Clin Transplant. 2024 Jan;22(Suppl 2):1-14. doi: 10.6002/ect.2023.0074.ABSTRACTIn December 2019, an outbreak caused by novel coronavirus 2019 (COVID-19) started in Wuhan, China. After extensive speculation about a causative agent, a novel betacoronavirus, in the same family as SARS-CoV and MERS-CoV, was identified via next-generation sequencing from samples received from several pneumonia patients. Ribonucleic acid extracted from the patient's bronchoalveolar lavage fluid was used as a template to clone and sequence the genome of SARS-CoV-2. Shortly after, the World Health Organization announced a worldwide pandemic. H...
Source: Experimental and Clinical Transplantation : official journal of the Middle East Society for Organ Transplantation - February 22, 2024 Category: Transplant Surgery Authors: Antoine Barbari Source Type: research
