TWiV 1104: Clinical update with Dr. Daniel Griffin
In his weekly clinical update, Dr. Griffin reviews recent statistics on the circulation of measles before addressing results of Pfizer’s phase 3 RSV vaccine clinical trial for adults under 60, RSV, influenza and SARS-CoV-2 circulation, differences between rural and urban communities dealing with SARS-CoV-2 infections, the latest statistics on influenza and COVID-19 circulation, restates the guidelines for spring administration of COVID vaccines boosters, discusses the emergency use application of a pre-exposure prophylactic. revised guidelines for how to treat respiratory viral infection guidelines by the CDC, continues ...
Source: This Week in Virology - MP3 Edition - April 13, 2024 Category: Virology Authors: Vincent Racaniello Source Type: podcasts

TWiV 1093: Reservoir bats and jumbo phage
TWiV discusses effectiveness of this season’s flu vaccine, efficacy of Pfizer RSV vaccine, nOPV2 in the US, dengue in Peru, measles in Michigan and Indiana, how coordinated inflammatory responses dictate control of Marburg virus by reservoir bats, and tRNA acquisition in phages driven by degradation of host translational machinery. Hosts: Vincent Racaniello, Rich Condit, Kathy Spindler, Brianne Barker, and Jolene Ramsey Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode MicrobeTV Discord Server MicrobeTV store at Cafepress Become a member of ASV (asv...
Source: This Week in Virology - MP3 Edition - March 3, 2024 Category: Virology Authors: Vincent Racaniello Source Type: podcasts

TWiV 1065: Cat coronavirus gains function in Cyprus
TWiV reviews ban on gain-of-function research by the House, chronic wasting disease in Tennessee deer, nOPV2 causing paralysis in children, and an outbreak of feline infectious peritonitis in Cyprus caused by a new recombinant coronavirus. Hosts: Vincent Racaniello, Dickson Despommier, Alan Dove, Rich Condit, Kathy Spindler, and Brianne Barker Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode MicrobeTV Discord Server MicrobeTV store at Cafepress Global Scholar Travel Awards (ASV) Research assistant position in Rosenfeld Lab CBER/FDA (pdf) The New City by Di...
Source: This Week in Virology - MP3 Edition - November 26, 2023 Category: Virology Authors: Vincent Racaniello Source Type: podcasts

TWiV 1040: Clinical update with Dr. Daniel Griffin
In his weekly clinical update, Dr. Griffin discusses the public health significance of finding autochthonous melioidosis cases in the continental United States, human neural larva migrans caused by Ophidascaris robertsi ascarid, Project nextgen awards over $1.4 billion to develop the future of COVID-19 vaccines and therapeutics, excess all-cause mortality in China after ending the zero COVID policy, international pediatric COVID-19 severity over the course of the pandemic, differences in SARS-CoV-2 specific humoral and cellular immune responses after contralateral and ipsilateral COVID-19 vaccination, Pfizer and BioNTech ...
Source: This Week in Virology - MP3 Edition - September 2, 2023 Category: Virology Authors: Vincent Racaniello Source Type: podcasts

TWiV 1012: Clinical update with Dr. Daniel Griffin
In his weekly clinical update, Dr. Griffin discusses the potential for recurrent Mpox outbreaks among gay, bisexual, and other men who have sex with men, association between SARS-CoV-2 variants and frequency of acute symptoms, prospective study of key correlates for household transmission of SARS-CoV-2, Pfizer’s PAXLOVID™ receiving FDA approval for adult patients at high risk of progression to severe COVID-19, efficacy and safety of antimicrobial stewardship prospective audit and feedback in patients hospitalized with COVID-19, development of a definition of postacute sequelae of SARS-CoV-2 infection, COVID-19 and risk...
Source: This Week in Virology - MP3 Edition - June 3, 2023 Category: Virology Authors: Vincent Racaniello Source Type: podcasts

TWiV 1010: Clinical update with Dr. Daniel Griffin
In his weekly clinical update, Dr. Griffin discusses the CDC HIV surveillance report, FDA voted in favor of approving the Abrysvo vaccine, canine olfactory detection of SARS-CoV-2-infected humans, safety of the BNT162b2 COVID-19 vaccine in children aged 5 to 17 years, and statement on the antigen composition of COVID-19 vaccines. Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode HIV surveillance report (CDC) FDA voted in favor of approving Abrysvo vaccine (Pfizer) Canine olfactory detection of SARS-CoV-2-infected humans (Annals of Epidemiology) Safety o...
Source: This Week in Virology - MP3 Edition - May 27, 2023 Category: Virology Authors: Vincent Racaniello Source Type: podcasts

TWiV 930: Clinical update with Dr. Daniel Griffin
In his weekly clinical update Dr. Griffin discusses antibody response against nonpoliovirus enteroviruses, clinical presentation and virological assessment of confirmed human monkeypox virus cases in Spain, object and surface contamination with monkeypox virus, monkeypox virus infection in humans across 16 countries, clinical characteristics of ambulatory and hospitalized patients with monkeypox virus infection, compassionate use of Tecovirimat for the treatment of monkeypox infection, monitoring of Pfizer-BioNTech vaccine among children, Pfizer and BioNTech announce updated vaccine data supporting efficacy in children, d...
Source: This Week in Virology - MP3 Edition - August 27, 2022 Category: Virology Authors: Vincent Racaniello Source Type: podcasts

TWiV 928: Clinical update with Dr. Daniel Griffin
In his weekly clinical update Dr. Griffin discusses the public health response to a polio case in a unvaccinated NY state resident, human to dog transmission of monkeypox virus, Tecovirimat and the treatment of monkeypox, detection of asymptomatic monkeypox virus infections among male sexual health clinic attendees in Belgium, what to do if you are exposed to SARS-CoV-2 and isolation and precautions for people with COVID-19, risk of SARS-CoV-2 infection in health care workers, effectiveness of HEPA filters at removing infectious SARS-CoV-2 from the air, Pfizer reports additional data on Paxlovid, hospitalization encou...
Source: This Week in Virology - MP3 Edition - August 20, 2022 Category: Virology Authors: Vincent Racaniello Source Type: podcasts

TWiV 903: COVID-19 clinical update #116 with Dr. Daniel Griffin
In COVID-19 clinical update #115, Dr. Griffin discusses croup association with infection surge, rhinovirus co-circulation in children, shedding following vaccination, high vaccine efficacy in children 6 mo-5 yr, vaccine protection for hospitalized patients, convalescent plasma as post-exposure prophylaxis, real-world effectiveness of PAXLOVID, effectiveness of PAXLOVID in reducing hospitalization, infection rebound after PAXLOVID, relapse of symptomatic infection after PAXLOVID, remdesivir and bebtelovimab fact sheets for providers, guidelines on usage of anticoagulation drugs, long covid symptoms after vaccina...
Source: This Week in Virology - MP3 Edition - May 28, 2022 Category: Virology Authors: Vincent Racaniello Source Type: podcasts

TWiV 897: COVID-19 clinical update #113 with Dr. Daniel Griffin
In COVID-19 clinical update #113, Dr. Griffin discusses tocilizumab use in hospitalized Patients, IL-6 inhibitors and mortality, Baricitinib in hospitalized patients, post-infection neurological sequelae, comparative effectiveness of Pfizer and Moderna vaccines, phase 2/3 study of Paxlovid, infection relapse following Paxlovid, pre-hospital administration of Remdesivir, and hospitalization with different variants. Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode Timing of Tocilizumab Use in Hospitalized Patients (NIH) Interleukin-6 inhibitors redu...
Source: This Week in Virology - MP3 Edition - May 7, 2022 Category: Virology Authors: Vincent Racaniello Source Type: podcasts

TWiV 892: COVID-19 clinical update #111 with Dr. Daniel Griffin
In COVID-19 clinical update #111, Dr. Griffin discusses vaccine coverage and mortality in Hong Kong, immune response to boosters in kids, hospitalization of kids, breath based diagnostic test, viral co-infections, bivalent mRNA vaccine, intramuscular Evusheld, and global long COVID. Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode Vaccine coverage and mortality, Hong Kong (MMWR) Kids behind on routine vaccinations (Politico) Immune response to booster, 5-11 year olds (Pfizer) Children and vaccination (AAP) Hospitalization of 5-11 year olds (MMWR) Test usin...
Source: This Week in Virology - MP3 Edition - April 23, 2022 Category: Virology Authors: Vincent Racaniello Source Type: podcasts

TWiV 889: COVID-19 clinical update #110 with Dr. Daniel Griffin
In COVID-19 clinical update #110, Dr. Griffin covers hospital admissions during variant outbreaks, viral load in vaccinated and unvaccinated individuals, predictive capacity of symptoms in children, comparison of antigen tests, incidence of myocarditis after vaccination, steroids during replication phase, Paxlovid efficacy and safety, fluvoxamine, sabizabutin, colchicine, and prevalence of infection in Africa. Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode Hospital admissions during Omicron and Delta variant outbreaks (Lancet) Viral load in unvaccinat...
Source: This Week in Virology - MP3 Edition - April 16, 2022 Category: Virology Authors: Vincent Racaniello Source Type: podcasts

TWiV 877: COVID-19 clinical update #106 with Dr. Daniel Griffin
In COVID-19 clinical update #106, Daniel Griffin covers failure of ivermectin to improve hospitalization, increased hospitalization of children with Omicron, seroconversion of children versus adults, effectiveness of Pfizer mRNA vaccine in children, high vaccine effectiveness in Finland against Omicron, distinct long COVID clinical phenotypes, and estimating worldwide excess mortality. Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode Ivermectin did not reduce hospitalizations (Wall St J) Increased hospitalization of children with Omicron (MMWR) Seroconver...
Source: This Week in Virology - MP3 Edition - March 19, 2022 Category: Virology Authors: Vincent Racaniello Source Type: podcasts

TWiV 874: COVID-19 clinical update #105 with Dr. Daniel Griffin
In COVID-19 clinical update #105, Daniel Griffin discusses changes in brain structure after infection, dementia in patients with pneumonia, Paxlovid in children, mask effectiveness in schools, host factors and severe disease, post-acute symptoms, and the mission of CEPI. Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode Infection and changes in brain structure (Nature) Dementia among pneumonia survivors (Open Forum Inf Dis) Narrative dynamics around COVID-19 vaccines (FSI) Children and COVID (AAP) Paxlovid in pediatric patients (Pfizer) Mask effectiveness i...
Source: This Week in Virology - MP3 Edition - March 12, 2022 Category: Virology Authors: Vincent Racaniello Source Type: podcasts

TWiV 862: COVID-19 clinical update #100 with Dr. Daniel Griffin
In COVID-19 clinical update #100, Daniel Griffin, from Accra, Ghana, reviews the challenges in evaluating Omicron severity, over 800 deaths in children, Pfizer vaccine EUA application for under 5 year olds, false positives from soft drinks, Novavax vaccine EUA application, childhood experiences and vaccine hesitancy, fourth vaccine dose in Israel, effects of antivirals and monoclonals against Omicron, and multiple factors associated with PASC. Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode Omicron severity challenges (NEJM) Children and COVID data (AAP) ...
Source: This Week in Virology - MP3 Edition - February 5, 2022 Category: Virology Authors: Vincent Racaniello Source Type: podcasts