Use of the Pfizer Pentavalent Meningococcal Vaccine Among Persons Aged ≥10 Years: Recommendations of the Advisory Committee on Immunization Practices - United States, 2023
This report summarizes evidence considered for these recommendations and provides clinical guidance for the use of MenACWY-TT/MenB-FHbp.PMID:38635488 | DOI:10.15585/mmwr.mm7315a4 (Source: MMWR Morb Mortal Wkl...)
Source: MMWR Morb Mortal Wkl... - April 18, 2024 Category: Epidemiology Authors: Jennifer P Collins Samuel J Crowe Ismael R Ortega-Sanchez Lynn Bahta Doug Campos-Outcalt Jamie Loehr Rebecca L Morgan Katherine A Poehling Lucy A McNamara Source Type: research
Extracorporeal membrane oxygenation (ECMO) during aplasia: A bridge towards myopericarditis recovery after autologous hematopoietic stem cell transplant for systemic sclerosis and recent Coronarovirus disease (COVID-19) vaccination
This report illustrates, for the first time to our knowledge, that ECMO can be indicated despite aplasia during aHSCT and successfully used as a bridge towards heart function recovery in highly selected and fragile AD patients. We review the factors that may contribute to endothelial and myocardial stunning and acute reversible cardiac failure in SSc and aggravate intrinsic endothelial injury during the aHSCT procedure. These classically include: cyclophosphamide drug toxicity, viral infections and autoimmune activation with disease flair per se. In the COVID-19 pandemic times, acute myocarditis due to recent viral infecti...
Source: Cell Research - April 18, 2024 Category: Cytology Authors: Carlotta Cacciatore Mathilde Baudet Estelle Jean Simona Presente Marylou Para Romain Sonneville Dimitri Arangalage Nassim Ait Abdallah Flore Sicre de Fontbrune Pedro Henrique Prata Benjamin Crichi Baptiste Hervier Nathalie Parquet Gilles Soulat Elie Mouss Source Type: research
Development and validation of a 6-plex Luminex-based assay for measuring human serum antibodies to group B streptococcus capsular polysaccharides
Volume 20, Issue 1, December 2024 . (Source: Human Vaccines and Immunotherapeutics)
Source: Human Vaccines and Immunotherapeutics - April 12, 2024 Category: Allergy & Immunology Authors: Michelle A. GaylordMelissa LarrierDonna Giordano-SchmidtChristopher D. GrubeSuddham SinghHa H. NguyenAndrew McKeenCharles Y. TanAnnaliesa S. AndersonWarren V. KalinaDanka PavliakovaPeter C. Giardinaa Vaccine Research and Development, Pfizer Inc, Pearl Riv Source Type: research
Immunogenicity and safety of Sinovac-CoronaVac booster vaccinations in 12-17- year-olds with clinically significant reactions from Pfizer-BNT162b2 vaccination
Vaccine. 2024 Apr 6:S0264-410X(24)00425-0. doi: 10.1016/j.vaccine.2024.04.011. Online ahead of print.ABSTRACTHeterologous Sinovac-CoronaVac booster(s) in 12-17-year-olds who had a moderate/severe reaction to Pfizer-BNT162b2 mRNA vaccine was found to safe with no serious adverse events reported. In those primed with 1 dose of Pfizer-BNT162b2 vaccine, subsequent boosters with 2 doses of Sinovac-CoronaVac vaccines achieved neutralizing antibody levels which were comparable to those who had received 2 doses of Pfizer-BNT162b2 vaccines followed by 1 dose of Sinovac-CoronaVac vaccination. Adolescents with 1 Pfizer-BNT162b2 follo...
Source: Vaccine - April 7, 2024 Category: Allergy & Immunology Authors: Chia-Yin Chong Kai-Qian Kam Jinyan Zhang Antonio Bertoletti Smrithi Hariharaputran Rehena Sultana Rupini Piragasam Yun-Yan Mah Chee-Wah Tan Linfa Wang Chee-Fu Yung Source Type: research
Immunogenicity and safety of Sinovac-CoronaVac booster vaccinations in 12-17- year-olds with clinically significant reactions from Pfizer-BNT162b2 vaccination
Vaccine. 2024 Apr 6:S0264-410X(24)00425-0. doi: 10.1016/j.vaccine.2024.04.011. Online ahead of print.ABSTRACTHeterologous Sinovac-CoronaVac booster(s) in 12-17-year-olds who had a moderate/severe reaction to Pfizer-BNT162b2 mRNA vaccine was found to safe with no serious adverse events reported. In those primed with 1 dose of Pfizer-BNT162b2 vaccine, subsequent boosters with 2 doses of Sinovac-CoronaVac vaccines achieved neutralizing antibody levels which were comparable to those who had received 2 doses of Pfizer-BNT162b2 vaccines followed by 1 dose of Sinovac-CoronaVac vaccination. Adolescents with 1 Pfizer-BNT162b2 follo...
Source: Vaccine - April 7, 2024 Category: Allergy & Immunology Authors: Chia-Yin Chong Kai-Qian Kam Jinyan Zhang Antonio Bertoletti Smrithi Hariharaputran Rehena Sultana Rupini Piragasam Yun-Yan Mah Chee-Wah Tan Linfa Wang Chee-Fu Yung Source Type: research
Immunogenicity and safety of Sinovac-CoronaVac booster vaccinations in 12-17- year-olds with clinically significant reactions from Pfizer-BNT162b2 vaccination
Vaccine. 2024 Apr 6:S0264-410X(24)00425-0. doi: 10.1016/j.vaccine.2024.04.011. Online ahead of print.ABSTRACTHeterologous Sinovac-CoronaVac booster(s) in 12-17-year-olds who had a moderate/severe reaction to Pfizer-BNT162b2 mRNA vaccine was found to safe with no serious adverse events reported. In those primed with 1 dose of Pfizer-BNT162b2 vaccine, subsequent boosters with 2 doses of Sinovac-CoronaVac vaccines achieved neutralizing antibody levels which were comparable to those who had received 2 doses of Pfizer-BNT162b2 vaccines followed by 1 dose of Sinovac-CoronaVac vaccination. Adolescents with 1 Pfizer-BNT162b2 follo...
Source: Vaccine - April 7, 2024 Category: Allergy & Immunology Authors: Chia-Yin Chong Kai-Qian Kam Jinyan Zhang Antonio Bertoletti Smrithi Hariharaputran Rehena Sultana Rupini Piragasam Yun-Yan Mah Chee-Wah Tan Linfa Wang Chee-Fu Yung Source Type: research
Detection of SARS-CoV-2-specific mucosal antibodies in saliva following concomitant COVID-19 and influenza vaccination in the ComFluCOV trial
Vaccine. 2024 Apr 4:S0264-410X(24)00367-0. doi: 10.1016/j.vaccine.2024.03.061. Online ahead of print.ABSTRACTThe ComFluCOV trial randomized 679 participants to receive an age-appropriate influenza vaccine, or placebo, alongside their second COVID-19 vaccine. Concomitant administration was shown to be safe, and to preserve systemic immune responses to both vaccines. Here we report on a secondary outcome of the trial investigating SARS-CoV-2-specific mucosal antibody responses. Anti-spike IgG and IgA levels in saliva were measured with in-house ELISAs. Concomitant administration of an influenza vaccine did not affect salivar...
Source: Vaccine - April 5, 2024 Category: Allergy & Immunology Authors: Holly E Baum Russell Thirard Alice Halliday Sarah Baos Amy C Thomas Rosie A Harris Elizabeth Oliver Lucy Culliford Benjamin Hitchings Rachel Todd Kapil Gupta Anu Goenka Adam Finn Chris A Rogers Rajeka Lazarus ComFluCOV Trial Group Source Type: research
A comparison of four self-controlled study designs in an analysis of COVID-19 vaccines and myocarditis using five European databases
CONCLUSIONS: In the context of the known association between COVID-19 vaccines and myocarditis, we have demonstrated that two forms of SCRI and two forms of SCCS led to largely comparable results, possibly because of limited violation of the assumption of event-dependent exposures.PMID:38580517 | DOI:10.1016/j.vaccine.2024.03.043 (Source: Vaccine)
Source: Vaccine - April 5, 2024 Category: Allergy & Immunology Authors: Anna Schultze Ivonne Martin Davide Messina Sophie Bots Svetlana Belitser Juan Jos é Carreras-Martínez Elisa Correcher-Martinez Arantxa Urchuegu ía-Fornes Mar Mart ín-Pérez Patricia Garc ía-Poza Felipe Villalobos Meritxell Pallej à-Millán Carlo Alb Source Type: research
Long-term course of neutralising antibodies against SARS-CoV-2 in vaccinated and unvaccinated staff and residents in a Swiss nursing home: a cohort study 2021-2022
CONCLUSIONS: Our study of the long-term serological course of SARS-CoV-2 in a nursing home showed that the first SARS-CoV-2 booster vaccine was essential for maintaining antiviral antibody levels. Hybrid immunity sustained SARS-CoV-2 immunity at the highest level. In critical settings such as nursing homes, monitoring the SARS-CoV-2 immune status may guide booster vaccinations.PMID:38579325 | DOI:10.57187/s.3502 (Source: Swiss Medical Weekly)
Source: Swiss Medical Weekly - April 5, 2024 Category: General Medicine Authors: Lisa Perrig Irene A Abela Nicolas Banholzer Annette Audig é Selina Epp Catrina Mugglin Kathrin Z ürcher Matthias Egger Alexandra Trkola Lukas Fenner Source Type: research
Detection of SARS-CoV-2-specific mucosal antibodies in saliva following concomitant COVID-19 and influenza vaccination in the ComFluCOV trial
Vaccine. 2024 Apr 4:S0264-410X(24)00367-0. doi: 10.1016/j.vaccine.2024.03.061. Online ahead of print.ABSTRACTThe ComFluCOV trial randomized 679 participants to receive an age-appropriate influenza vaccine, or placebo, alongside their second COVID-19 vaccine. Concomitant administration was shown to be safe, and to preserve systemic immune responses to both vaccines. Here we report on a secondary outcome of the trial investigating SARS-CoV-2-specific mucosal antibody responses. Anti-spike IgG and IgA levels in saliva were measured with in-house ELISAs. Concomitant administration of an influenza vaccine did not affect salivar...
Source: Vaccine - April 5, 2024 Category: Allergy & Immunology Authors: Holly E Baum Russell Thirard Alice Halliday Sarah Baos Amy C Thomas Rosie A Harris Elizabeth Oliver Lucy Culliford Benjamin Hitchings Rachel Todd Kapil Gupta Anu Goenka Adam Finn Chris A Rogers Rajeka Lazarus ComFluCOV Trial Group Source Type: research
A comparison of four self-controlled study designs in an analysis of COVID-19 vaccines and myocarditis using five European databases
CONCLUSIONS: In the context of the known association between COVID-19 vaccines and myocarditis, we have demonstrated that two forms of SCRI and two forms of SCCS led to largely comparable results, possibly because of limited violation of the assumption of event-dependent exposures.PMID:38580517 | DOI:10.1016/j.vaccine.2024.03.043 (Source: Vaccine)
Source: Vaccine - April 5, 2024 Category: Allergy & Immunology Authors: Anna Schultze Ivonne Martin Davide Messina Sophie Bots Svetlana Belitser Juan Jos é Carreras-Martínez Elisa Correcher-Martinez Arantxa Urchuegu ía-Fornes Mar Mart ín-Pérez Patricia Garc ía-Poza Felipe Villalobos Meritxell Pallej à-Millán Carlo Alb Source Type: research
Long-term course of neutralising antibodies against SARS-CoV-2 in vaccinated and unvaccinated staff and residents in a Swiss nursing home: a cohort study 2021-2022
CONCLUSIONS: Our study of the long-term serological course of SARS-CoV-2 in a nursing home showed that the first SARS-CoV-2 booster vaccine was essential for maintaining antiviral antibody levels. Hybrid immunity sustained SARS-CoV-2 immunity at the highest level. In critical settings such as nursing homes, monitoring the SARS-CoV-2 immune status may guide booster vaccinations.PMID:38579325 | DOI:10.57187/s.3502 (Source: Swiss Medical Weekly)
Source: Swiss Medical Weekly - April 5, 2024 Category: General Medicine Authors: Lisa Perrig Irene A Abela Nicolas Banholzer Annette Audig é Selina Epp Catrina Mugglin Kathrin Z ürcher Matthias Egger Alexandra Trkola Lukas Fenner Source Type: research
Long-term course of neutralising antibodies against SARS-CoV-2 in vaccinated and unvaccinated staff and residents in a Swiss nursing home: a cohort study 2021-2022
CONCLUSIONS: Our study of the long-term serological course of SARS-CoV-2 in a nursing home showed that the first SARS-CoV-2 booster vaccine was essential for maintaining antiviral antibody levels. Hybrid immunity sustained SARS-CoV-2 immunity at the highest level. In critical settings such as nursing homes, monitoring the SARS-CoV-2 immune status may guide booster vaccinations.PMID:38579325 | DOI:10.57187/s.3502 (Source: Swiss Medical Weekly)
Source: Swiss Medical Weekly - April 5, 2024 Category: General Medicine Authors: Lisa Perrig Irene A Abela Nicolas Banholzer Annette Audig é Selina Epp Catrina Mugglin Kathrin Z ürcher Matthias Egger Alexandra Trkola Lukas Fenner Source Type: research
News at a glance: Giant telescope camera complete, limits to Paxlovid benefits, and missing battlefield bones
ASTRONOMY
Biggest ever digital camera heads to Chile
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Researchers at the SLAC National Accelerator Laboratory have finished building the biggest ever astronomical camera. It will create a movie of the universe, imaging the whole southern sky in unprecedented detail every 3 days.
Jacqueline Ramseyer Orrell/SLAC National Accelerator Laboratory
Researchers install the first of 21 arrays of image sensors that together make up the camer...
Source: Science of Aging Knowledge Environment - April 4, 2024 Category: Geriatrics Source Type: research
Evaluation of the hematological and immunological markers after the first and second doses of BNT162b2 mRNA vaccine
CONCLUSIONS: We can conclude that the Pfizer/BioNTech vaccine produced a more potent T-cell response than humoral ones.PMID:38567619 | DOI:10.26355/eurrev_202403_35766 (Source: Pharmacological Reviews)
Source: Pharmacological Reviews - April 3, 2024 Category: Drugs & Pharmacology Authors: M Rafeeq M S Jabir H M Al-Kuraishy Z M A Jeddoa S F Jawad M A A Najm A F Almulla E Elekhnawy J Z Tayyeb A Turkistani B A Alsfouk G E Batiha Source Type: research
