End of life decision making when home mechanical ventilation is used to sustain breathing in Motor Neurone Disease: patient and family perspectives
Motor Neurone Disease (MND) leads to muscle weakening, affecting movement, speech, and breathing. Home mechanical ventilation, particularly non-invasive ventilation (NIV), is used to alleviate symptoms and sup... (Source: BMC Palliative Care)
Source: BMC Palliative Care - May 2, 2024 Category: Palliative Care Authors: Eleanor Wilson, Jonathan Palmer, Alison Armstrong, Ben Messer, Edward Presswood and Christina Faull Tags: Research Source Type: research

Medicinal Cannabis (MedCan 3): a randomised, multicentre, double-blind, placebo-controlled trial to assess THC/CBD (1:20) to relieve symptom burden in patients with cancer-a study protocol for a randomised controlled trial
This study aims to assess a 1:20 delta-9-tetrahydrocannabinol/cannabidiol (THC/CBD) cannabinoid preparation in the management of symptom distress in patients with advanced cancer undergoing palliative care.METHODS AND DESIGN: One hundred and fifty participants will be recruited across multiple sites in Queensland, Australia. A teletrial model will facilitate the recruitment of patients outside of major metropolitan areas. The study is a pragmatic, multicenter, randomised, placebo-controlled, two-arm trial of escalating doses of an oral 1:20 THC/CBD medicinal cannabinoid preparation (10 mg THC:200 mg CBD/mL). It will compar...
Source: Rural Remote Health - May 1, 2024 Category: Rural Health Authors: Taylan Gurgenci Janet Hardy Georgie Huggett Karyn Foster Anita Pelecanos Ristan Greer Jennifer Philip Alison Haywood Ruwani Mendis Patsy Yates Phillip Good Source Type: research

Hospice Guidelines for Parkinson ’s Disease and Related Disorders: Lessons Learned from a Palliative Program
Background: There are no specific guidelines for hospice for PDRD leading to delayed or lack of referrals to hospice and its resources at end of life. (Source: Parkinsonism and Related Disorders)
Source: Parkinsonism and Related Disorders - May 1, 2024 Category: Neurology Authors: J. Chan, T. Gossard, A. Breitenbucher, H. Shill Source Type: research

QI Project introducing A Reflective-Education Model Optimizing Palliative Care Delivery: A Multidisciplinary and Primary Care Integration Model
Background: A QI project in the palliative framework at USTH involving 3 domains of palliative care service provisions has reformulated the available services in the institution. Aligning with the globalization of UHC 11223, it aimed to set deliverables as efficient and effective as it can possibly be through process-remodeling, in a projected period of timeline and timeframe. Detailed improvement upscaling approach , catered to existing protocols that were identified to be needing efficiency and effectiveness, inclusive of the following: (Source: Parkinsonism and Related Disorders)
Source: Parkinsonism and Related Disorders - May 1, 2024 Category: Neurology Authors: M. Bacorro, M. Bautista, M. Mejia, W. Bacorro, M. Valencia, M. Maranion, J. Diaz, A. Fernando, M. Pasicolan Source Type: research

American Society for Pain Management Nursing and Hospice and Palliative Nurses Association Position Statement: Pain Management at the End of Life
Fundamental to the quality of life is assisting patients in relieving pain including at the end of life. Compassionate, effective, evidence-based pain care for the dying improves the quality of life for patients and may reduce distress and complicated bereavement in the loved ones witnessing this death. However, efforts designed to mitigate the consequences of the opioid epidemic have seriously compromised pain care at the end of life. This has created an urgent need to focus on the barriers to relief, and solutions necessary to provide safe and effective pain and symptom management in this population. (Source: Pain Management Nursing)
Source: Pain Management Nursing - May 1, 2024 Category: Nursing Authors: Patrick Coyne, Sarah Lowry, Carol Mulvenon, Judith A. Paice Source Type: research

Development of palliative care clinical practice guidelines and referral care pathways for primary care practitioners in Pakistan
Despite a large burden of life-limitingillness, there exists a dearth of services of palliative care in Pakistan. International guidelines have questionable applicability in Pakistan due to the socioeconomic d... (Source: BMC Palliative Care)
Source: BMC Palliative Care - May 1, 2024 Category: Palliative Care Authors: Syeda Amrah Hashmi, Russell Seth Martins, Annum Ishtiaq, Nashia Ali Rizvi, Mohsin Ali Mustafa, Alina Pervez, Ayra Siddiqui, Syeda Fatima Shariq, Sarah Nadeem, Adil H. Haider and Muhammad Atif Waqar Tags: Research Source Type: research

Exploring Effective Approaches: Integrating Mental Health Services into HIV Clinics in Northern Uganda
(Source: Therapeutics and Clinical Risk Management)
Source: Therapeutics and Clinical Risk Management - April 30, 2024 Category: Drugs & Pharmacology Tags: HIV/AIDS - Research and Palliative Care Source Type: research

A Review and Case Study of Genital and Extragenital Human Papillomavirus Type 6 and 11 Infections in Men Who Have Sex with Men Accompanied by Human Immunodeficiency Virus Infection
(Source: Therapeutics and Clinical Risk Management)
Source: Therapeutics and Clinical Risk Management - April 30, 2024 Category: Drugs & Pharmacology Tags: HIV/AIDS - Research and Palliative Care Source Type: research

Synchronous Double Primary Angiosarcoma Originating from the Stomach and Rectum: A Case Report and a Literature Review
Arch Iran Med. 2024 Mar 1;27(3):168-173. doi: 10.34172/aim.2024.25.ABSTRACTAngiosarcomas originating from the gastrointestinal tract are rare but highly aggressive tumors with poor prognosis. These tumors can be misdiagnosed as benign and malignant gastrointestinal tract lesions. The definitive histological diagnosis of angiosarcomasis made by pathologists based on immunohistochemical analysis demonstrating cluster of differentiation 31 (CD31), factor VIII-related antigen (FVIIIRAg), erythroblast transformation specific related gene (ERG), and cluster of differentiation 34 (CD34). Angiosarcomas are treated with a single or...
Source: Archives of Iranian Medicine - April 30, 2024 Category: Middle East Health Authors: Tanju Kapagan Nilufer Bulut Gokmen Umut Erdem Suleyman Y ıldırım Zeynep Betul Erdem Halil Sahin Source Type: research

Successful treatment with nivolumab in a patient with gastric cancer with severe liver failure resulting from multiple liver metastases: A case report
Oncol Lett. 2024 Apr 18;27(6):271. doi: 10.3892/ol.2024.14404. eCollection 2024 Jun.ABSTRACTGastric cancer (GC) is a globally prevalent and deadly malignancy often diagnosed at advanced stages, which can be accompanied by liver metastases. Conventional chemotherapy is contraindicated in patients with severe liver failure because several chemotherapeutic agents are metabolized by the liver. The present study reports on the successful use of nivolumab in a patient with advanced GC and severe liver failure owing to multiple liver metastases. A 57-year-old man was admitted to Shimane Prefectural Central Hospital (Izumo, Japan)...
Source: Oncology Letters - April 30, 2024 Category: Cancer & Oncology Authors: Fumiyoshi Ikejiri Kanako Yokomizo Kenji Tamura Source Type: research

Comparative Analysis of Quality of Life of Family Caregivers of Patients With Heart Failure and Cancer Who Receive Palliative Care
CONCLUSIONS: Overall, healthcare professionals should focus on improving social support and caregiver role adoption and provide greater attention to the QoL of caregivers of patients with cancer.PMID:38687116 | DOI:10.1097/JCN.0000000000001097 (Source: The Journal of Cardiovascular Nursing)
Source: The Journal of Cardiovascular Nursing - April 30, 2024 Category: Nursing Authors: Mauricio Arias-Rojas Edith Arredondo Holg ín Sonia Carre ño-Moreno Source Type: research

Synchronous Double Primary Angiosarcoma Originating from the Stomach and Rectum: A Case Report and a Literature Review
Arch Iran Med. 2024 Mar 1;27(3):168-173. doi: 10.34172/aim.2024.25.ABSTRACTAngiosarcomas originating from the gastrointestinal tract are rare but highly aggressive tumors with poor prognosis. These tumors can be misdiagnosed as benign and malignant gastrointestinal tract lesions. The definitive histological diagnosis of angiosarcomasis made by pathologists based on immunohistochemical analysis demonstrating cluster of differentiation 31 (CD31), factor VIII-related antigen (FVIIIRAg), erythroblast transformation specific related gene (ERG), and cluster of differentiation 34 (CD34). Angiosarcomas are treated with a single or...
Source: Archives of Iranian Medicine - April 30, 2024 Category: Middle East Health Authors: Tanju Kapagan Nilufer Bulut Gokmen Umut Erdem Suleyman Y ıldırım Zeynep Betul Erdem Halil Sahin Source Type: research

Successful treatment with nivolumab in a patient with gastric cancer with severe liver failure resulting from multiple liver metastases: A case report
Oncol Lett. 2024 Apr 18;27(6):271. doi: 10.3892/ol.2024.14404. eCollection 2024 Jun.ABSTRACTGastric cancer (GC) is a globally prevalent and deadly malignancy often diagnosed at advanced stages, which can be accompanied by liver metastases. Conventional chemotherapy is contraindicated in patients with severe liver failure because several chemotherapeutic agents are metabolized by the liver. The present study reports on the successful use of nivolumab in a patient with advanced GC and severe liver failure owing to multiple liver metastases. A 57-year-old man was admitted to Shimane Prefectural Central Hospital (Izumo, Japan)...
Source: Oncology Letters - April 30, 2024 Category: Cancer & Oncology Authors: Fumiyoshi Ikejiri Kanako Yokomizo Kenji Tamura Source Type: research

Comparative Analysis of Quality of Life of Family Caregivers of Patients With Heart Failure and Cancer Who Receive Palliative Care
CONCLUSIONS: Overall, healthcare professionals should focus on improving social support and caregiver role adoption and provide greater attention to the QoL of caregivers of patients with cancer.PMID:38687116 | DOI:10.1097/JCN.0000000000001097 (Source: The Journal of Cardiovascular Nursing)
Source: The Journal of Cardiovascular Nursing - April 30, 2024 Category: Nursing Authors: Mauricio Arias-Rojas Edith Arredondo Holg ín Sonia Carre ño-Moreno Source Type: research

Comparative Analysis of Quality of Life of Family Caregivers of Patients With Heart Failure and Cancer Who Receive Palliative Care
CONCLUSIONS: Overall, healthcare professionals should focus on improving social support and caregiver role adoption and provide greater attention to the QoL of caregivers of patients with cancer.PMID:38687116 | DOI:10.1097/JCN.0000000000001097 (Source: The Journal of Cardiovascular Nursing)
Source: The Journal of Cardiovascular Nursing - April 30, 2024 Category: Nursing Authors: Mauricio Arias-Rojas Edith Arredondo Holg ín Sonia Carre ño-Moreno Source Type: research