Transcutaneous Electrical Stimulation of the Abdomen, Ear, and Tibial Nerve Modulates Bladder Contraction in a Rat Detrusor Overactivity Model: A Pilot Study
CONCLUSION: The application of transcutaneous electrical stimulation to the abdominal wall, ear, and tibial nerve could provide less invasive and more cost-effective treatment options for OAB relative to percutaneous tibial nerve stimulation and sacral neuromodulation. A follow-up study involving a larger sample size is recommended.PMID:37798883 | DOI:10.5213/inj.2346144.072 (Source: International Neurourology Journal)
Source: International Neurourology Journal - October 6, 2023 Category: Urology & Nephrology Authors: Rosa L Coolen Dennis Frings Els van Asselt Jeroen R Scheepe Bertil F M Blok Source Type: research
H < sub > 2 < /sub > O < sub > 2 < /sub > enhances the spontaneous phasic contractions of isolated human-bladder strips via activation of TRPA1 channels on sensory nerves and the release of substance P and PGE2
Free Radic Biol Med. 2023 Oct 4:S0891-5849(23)00665-2. doi: 10.1016/j.freeradbiomed.2023.10.001. Online ahead of print.ABSTRACTSeveral studies have indicated that reactive oxygen species (ROS) can lead to detrusor overactivity (DO), but the underlying mechanisms are not known. Hydrogen dioxide (H2O2) is used commonly to investigate the effects of ROS. In present study, we investigated the effects of H2O2 on phasic spontaneous bladder contractions (SBCs) of isolated human-bladder strips (iHBSs) and the underlying mechanisms. Samples of bladder tissue were obtained from 26 patients undergoing cystectomy owing to bladder canc...
Source: Free Radical Biology and Medicine - October 6, 2023 Category: Biology Authors: Haoyu Wang Mengmeng Zhao Jiaxin Liu Lei Liu Hanwen Liu Ning Ding Jiliang Wen Shaoyong Wang Nan Ge Xiulin Zhang Source Type: research
Comparative Study Between Behavior Therapy and Behavior Therapy Plus Mirabegron 50 mg in Sexually Active Men With Bothersome Overactive Bladder Symptoms - A Multicenter, Randomized Study
CONCLUSION: Behavioral therapy combined with mirabegron had more significant impact on the improvement of OAB than behavior therapy alone. However, both groups did not have significant changes in erectile or ejaculatory function.PMID:37798885 | DOI:10.5213/inj.2346148.074 (Source: International Neurourology Journal)
Source: International Neurourology Journal - October 6, 2023 Category: Urology & Nephrology Authors: Chih-Chieh Lin Hann-Chorng Kuo Jian-Ri Li Yao-Chi Chuang Source Type: research
Transcutaneous Electrical Stimulation of the Abdomen, Ear, and Tibial Nerve Modulates Bladder Contraction in a Rat Detrusor Overactivity Model: A Pilot Study
CONCLUSION: The application of transcutaneous electrical stimulation to the abdominal wall, ear, and tibial nerve could provide less invasive and more cost-effective treatment options for OAB relative to percutaneous tibial nerve stimulation and sacral neuromodulation. A follow-up study involving a larger sample size is recommended.PMID:37798883 | DOI:10.5213/inj.2346144.072 (Source: International Neurourology Journal)
Source: International Neurourology Journal - October 6, 2023 Category: Urology & Nephrology Authors: Rosa L Coolen Dennis Frings Els van Asselt Jeroen R Scheepe Bertil F M Blok Source Type: research
H < sub > 2 < /sub > O < sub > 2 < /sub > enhances the spontaneous phasic contractions of isolated human-bladder strips via activation of TRPA1 channels on sensory nerves and the release of substance P and PGE2
Free Radic Biol Med. 2023 Oct 4:S0891-5849(23)00665-2. doi: 10.1016/j.freeradbiomed.2023.10.001. Online ahead of print.ABSTRACTSeveral studies have indicated that reactive oxygen species (ROS) can lead to detrusor overactivity (DO), but the underlying mechanisms are not known. Hydrogen dioxide (H2O2) is used commonly to investigate the effects of ROS. In present study, we investigated the effects of H2O2 on phasic spontaneous bladder contractions (SBCs) of isolated human-bladder strips (iHBSs) and the underlying mechanisms. Samples of bladder tissue were obtained from 26 patients undergoing cystectomy owing to bladder canc...
Source: Free Radical Biology and Medicine - October 6, 2023 Category: Biology Authors: Haoyu Wang Mengmeng Zhao Jiaxin Liu Lei Liu Hanwen Liu Ning Ding Jiliang Wen Shaoyong Wang Nan Ge Xiulin Zhang Source Type: research
Comparative Study Between Behavior Therapy and Behavior Therapy Plus Mirabegron 50 mg in Sexually Active Men With Bothersome Overactive Bladder Symptoms - A Multicenter, Randomized Study
CONCLUSION: Behavioral therapy combined with mirabegron had more significant impact on the improvement of OAB than behavior therapy alone. However, both groups did not have significant changes in erectile or ejaculatory function.PMID:37798885 | DOI:10.5213/inj.2346148.074 (Source: International Neurourology Journal)
Source: International Neurourology Journal - October 6, 2023 Category: Urology & Nephrology Authors: Chih-Chieh Lin Hann-Chorng Kuo Jian-Ri Li Yao-Chi Chuang Source Type: research
Transcutaneous Electrical Stimulation of the Abdomen, Ear, and Tibial Nerve Modulates Bladder Contraction in a Rat Detrusor Overactivity Model: A Pilot Study
CONCLUSION: The application of transcutaneous electrical stimulation to the abdominal wall, ear, and tibial nerve could provide less invasive and more cost-effective treatment options for OAB relative to percutaneous tibial nerve stimulation and sacral neuromodulation. A follow-up study involving a larger sample size is recommended.PMID:37798883 | DOI:10.5213/inj.2346144.072 (Source: International Neurourology Journal)
Source: International Neurourology Journal - October 6, 2023 Category: Urology & Nephrology Authors: Rosa L Coolen Dennis Frings Els van Asselt Jeroen R Scheepe Bertil F M Blok Source Type: research
Comparative Study Between Behavior Therapy and Behavior Therapy Plus Mirabegron 50 mg in Sexually Active Men With Bothersome Overactive Bladder Symptoms - A Multicenter, Randomized Study
CONCLUSION: Behavioral therapy combined with mirabegron had more significant impact on the improvement of OAB than behavior therapy alone. However, both groups did not have significant changes in erectile or ejaculatory function.PMID:37798885 | DOI:10.5213/inj.2346148.074 (Source: International Neurourology Journal)
Source: International Neurourology Journal - October 6, 2023 Category: Urology & Nephrology Authors: Chih-Chieh Lin Hann-Chorng Kuo Jian-Ri Li Yao-Chi Chuang Source Type: research
Transcutaneous Electrical Stimulation of the Abdomen, Ear, and Tibial Nerve Modulates Bladder Contraction in a Rat Detrusor Overactivity Model: A Pilot Study
CONCLUSION: The application of transcutaneous electrical stimulation to the abdominal wall, ear, and tibial nerve could provide less invasive and more cost-effective treatment options for OAB relative to percutaneous tibial nerve stimulation and sacral neuromodulation. A follow-up study involving a larger sample size is recommended.PMID:37798883 | DOI:10.5213/inj.2346144.072 (Source: International Neurourology Journal)
Source: International Neurourology Journal - October 6, 2023 Category: Urology & Nephrology Authors: Rosa L Coolen Dennis Frings Els van Asselt Jeroen R Scheepe Bertil F M Blok Source Type: research
Comparative Study Between Behavior Therapy and Behavior Therapy Plus Mirabegron 50 mg in Sexually Active Men With Bothersome Overactive Bladder Symptoms - A Multicenter, Randomized Study
CONCLUSION: Behavioral therapy combined with mirabegron had more significant impact on the improvement of OAB than behavior therapy alone. However, both groups did not have significant changes in erectile or ejaculatory function.PMID:37798885 | DOI:10.5213/inj.2346148.074 (Source: International Neurourology Journal)
Source: International Neurourology Journal - October 6, 2023 Category: Urology & Nephrology Authors: Chih-Chieh Lin Hann-Chorng Kuo Jian-Ri Li Yao-Chi Chuang Source Type: research
Transcutaneous Electrical Stimulation of the Abdomen, Ear, and Tibial Nerve Modulates Bladder Contraction in a Rat Detrusor Overactivity Model: A Pilot Study
CONCLUSION: The application of transcutaneous electrical stimulation to the abdominal wall, ear, and tibial nerve could provide less invasive and more cost-effective treatment options for OAB relative to percutaneous tibial nerve stimulation and sacral neuromodulation. A follow-up study involving a larger sample size is recommended.PMID:37798883 | DOI:10.5213/inj.2346144.072 (Source: International Neurourology Journal)
Source: International Neurourology Journal - October 6, 2023 Category: Urology & Nephrology Authors: Rosa L Coolen Dennis Frings Els van Asselt Jeroen R Scheepe Bertil F M Blok Source Type: research
Comparative Study Between Behavior Therapy and Behavior Therapy Plus Mirabegron 50 mg in Sexually Active Men With Bothersome Overactive Bladder Symptoms - A Multicenter, Randomized Study
CONCLUSION: Behavioral therapy combined with mirabegron had more significant impact on the improvement of OAB than behavior therapy alone. However, both groups did not have significant changes in erectile or ejaculatory function.PMID:37798885 | DOI:10.5213/inj.2346148.074 (Source: International Neurourology Journal)
Source: International Neurourology Journal - October 6, 2023 Category: Urology & Nephrology Authors: Chih-Chieh Lin Hann-Chorng Kuo Jian-Ri Li Yao-Chi Chuang Source Type: research
Transcutaneous Electrical Stimulation of the Abdomen, Ear, and Tibial Nerve Modulates Bladder Contraction in a Rat Detrusor Overactivity Model: A Pilot Study
CONCLUSION: The application of transcutaneous electrical stimulation to the abdominal wall, ear, and tibial nerve could provide less invasive and more cost-effective treatment options for OAB relative to percutaneous tibial nerve stimulation and sacral neuromodulation. A follow-up study involving a larger sample size is recommended.PMID:37798883 | DOI:10.5213/inj.2346144.072 (Source: International Neurourology Journal)
Source: International Neurourology Journal - October 6, 2023 Category: Urology & Nephrology Authors: Rosa L Coolen Dennis Frings Els van Asselt Jeroen R Scheepe Bertil F M Blok Source Type: research
Comparative Study Between Behavior Therapy and Behavior Therapy Plus Mirabegron 50 mg in Sexually Active Men With Bothersome Overactive Bladder Symptoms - A Multicenter, Randomized Study
CONCLUSION: Behavioral therapy combined with mirabegron had more significant impact on the improvement of OAB than behavior therapy alone. However, both groups did not have significant changes in erectile or ejaculatory function.PMID:37798885 | DOI:10.5213/inj.2346148.074 (Source: International Neurourology Journal)
Source: International Neurourology Journal - October 6, 2023 Category: Urology & Nephrology Authors: Chih-Chieh Lin Hann-Chorng Kuo Jian-Ri Li Yao-Chi Chuang Source Type: research
Transcutaneous Electrical Stimulation of the Abdomen, Ear, and Tibial Nerve Modulates Bladder Contraction in a Rat Detrusor Overactivity Model: A Pilot Study
CONCLUSION: The application of transcutaneous electrical stimulation to the abdominal wall, ear, and tibial nerve could provide less invasive and more cost-effective treatment options for OAB relative to percutaneous tibial nerve stimulation and sacral neuromodulation. A follow-up study involving a larger sample size is recommended.PMID:37798883 | DOI:10.5213/inj.2346144.072 (Source: International Neurourology Journal)
Source: International Neurourology Journal - October 6, 2023 Category: Urology & Nephrology Authors: Rosa L Coolen Dennis Frings Els van Asselt Jeroen R Scheepe Bertil F M Blok Source Type: research
