Comparison of B-Scan ultrasonography, ultra-widefield fundus imaging, and indirect ophthalmoscopy in detecting retinal breaks in cataractous eyes
Eye, Published online: 24 April 2024; doi:10.1038/s41433-024-03093-2Comparison of B-Scan ultrasonography, ultra-widefield fundus imaging, and indirect ophthalmoscopy in detecting retinal breaks in cataractous eyes (Source: Eye)
Source: Eye - April 24, 2024 Category: Opthalmology Authors: Ao Miao Jie Xu Kai Wei Peimin Lin Liangliang Niu Yumeng Shi Dongjin Qian Yi Lu Yongxiang Jiang Tianyu Zheng Source Type: research
Giant Cell Arteritis
Klin Monbl Augenheilkd. 2024 Apr 9. doi: 10.1055/a-2252-3371. Online ahead of print.ABSTRACTGiant cell arteritis (GCA) is the most common primary vasculitis and is associated with potential bilateral blindness. Neither clinical nor laboratory evidence is simple and unequivocal for this disease, which usually requires rapid and reliable diagnosis and therapy. The ophthalmologist should consider GCA with the following ocular symptoms: visual loss or visual field defects, transient visual disturbances (amaurosis fugax), diplopia, eye pain, or new onset head or jaw claudication. An immediate ophthalmological examination with s...
Source: Klinische Monatsblatter fur Augenheilkunde - April 9, 2024 Category: Opthalmology Authors: Thomas Ness Bernhard N ölle Source Type: research
Morphologic and Functional Assessment of Photoreceptors in Laser Induced Retinopathy Using Adaptive Optics-SLO and Microperimetry
To assess the cone photoreceptors morphology and associated retinal sensitivity in laser-induced retinopathy (LIR) using adaptive optics Scanning Laser Ophthalmoscopy (AO-SLO) and microperimetry (MP). (Source: American Journal of Ophthalmology)
Source: American Journal of Ophthalmology - March 28, 2024 Category: Opthalmology Authors: Dong Fang, Jia Liang, Yingying Diao, Dongmei Cui, Fei Hou, Bingru Zheng, Huiyan Zheng, Changfeng Pan, Lujia Feng, Wangting Li, Ting Xie, Pengfeng Li, Jie Zhang, Guoming Zhang, Lu Chen, Shaochong Zhang Tags: Original Articles Source Type: research
Needs assessment for direct ophthalmoscopy training in neurology residency
Assessment of the ocular fundus, traditionally by direct ophthalmoscopy (DO), is essential to evaluate many neurologic diseases. However, the status of DO training in neurology residencies is unknown. We condu... (Source: BMC Medical Education)
Source: BMC Medical Education - March 27, 2024 Category: Universities & Medical Training Authors: Jasmeet Saroya, Noor Chahal, Alice Jiang, Douglas Pet, Nailyn Rasool, Mark Terrelonge and Madeline Yung Tags: Research Source Type: research
Unified deep learning model for predicting fundus fluorescein angiography image from fundus structure image
Journal of Innovative Optical Health Sciences, Ahead of Print. The prediction of fundus fluorescein angiography (FFA) images from fundus structural images is a cutting-edge research topic in ophthalmological image processing. Prediction comprises estimating FFA from fundus camera imaging, single-phase FFA from scanning laser ophthalmoscopy (SLO), and three-phase FFA also from SLO. Although many deep learning models are available, a single model can only perform one or two of these prediction tasks. To accomplish three prediction tasks using a unified method, we propose a unified deep learning model for predicting FFA image...
Source: Journal of Innovative Optical Health Sciences - March 22, 2024 Category: Biomedical Science Authors: Yiwei Chen Yi He Hong Ye Lina Xing Xin Zhang Guohua Shi Source Type: research
Deep phenotyping of PROM1-associated retinal degeneration
Conclusions
PROM1-RD comprises a wide range of clinical phenotypes. Depending on the stage of disease, the cone mosaic in PROM1-RD is relatively preserved and can potentially be targeted by cone-directed interventions. (Source: British Journal of Ophthalmology)
Source: British Journal of Ophthalmology - March 20, 2024 Category: Opthalmology Authors: Schliessleder, G., Kalitzeos, A., Kasilian, M., Singh, N., Wang, Z., Hu, Z., Grosspötzl, M., Sadda, S., Wedrich, A., Michaelides, M., Strauss, R. W. Tags: Retina Source Type: research
Structural and functional characterization of an individual with the M285R < em > KCNV2 < /em > hypomorphic allele
CONCLUSIONS: We provide functional and structural evidence that the variant M285R is disease-causing if associated with a loss-of-function variant. To the best of our knowledge, this is the first hypomorphic allele reported in KCNV2.PMID:38454848 | DOI:10.1080/13816810.2024.2324046 (Source: Ophthalmic Genetics)
Source: Ophthalmic Genetics - March 8, 2024 Category: Opthalmology Authors: Thales A C de Guimaraes Francesco Lai Raffaella Colombatti Giovanni Sato Roberta Rizzo Angelos Kalitzeos Michel Michaelides Source Type: research
Intravitreal Delivery of PEGylated-ECO Plasmid DNA Nanoparticles for Gene Therapy of Stargardt Disease
ConclusionsIntravitreal delivery of the PEG-ELNP ofpGRK1-ABCA4-S/MAR is a promising approach for gene therapy of Stargardt Disease, which can also be a delivery platform for gene therapy of other inherited retinal diseases. (Source: Pharmaceutical Research)
Source: Pharmaceutical Research - March 5, 2024 Category: Drugs & Pharmacology Source Type: research
Quantitative Analysis of the Vasculature and Cone Photoreceptors in Subjects With Diabetes Without Diabetic Retinopathy
CONCLUSIONS: CS is the most sensitive CPG index for detecting alterations in the cone mosaic. The DCP and the cone photoreceptors are significantly correlated, indicating that alterations in the DCP can affect the cones. Future work elucidating the vascular alterations and neurodegeneration present in diabetic eyes should focus on the DCP and multiple CPG indices, not solely CD. Moreover, such alterations are highly localized, hence using larger regions e.g. parafovea versus smaller areas, such as the PTQ, will potentially mask significant correlations.PMID:38407181 | DOI:10.1080/02713683.2024.2320787 (Source: Current Eye Research)
Source: Current Eye Research - February 26, 2024 Category: Opthalmology Authors: Danae A Johnson Nathan Doble Stacey S Choi Source Type: research
