Multimodal high-resolution retinal imaging using a camera-based DMD-integrated adaptive optics flood-illumination ophthalmoscope
We demonstrate the feasibility of a multimodal adaptive optics flood-illumination ophthalmoscope, able to provide both bright-field and ... (Source: Optics Letters)
Source: Optics Letters - July 11, 2023 Category: Physics Authors: L é a Krafft Pierre Sen é e Elena Gofas Olivier Thouvenin Michael Atlan Michel Paques Serge Meimon Pedro Mec ê Source Type: research
Practical applications of vitreous imaging for the treatment of vitreous opacities with YAG vitreolysis
ConclusionImage-guided YLV facilitates the localization and confirmation of vitreous opacities. SLO and dynamic OCT of the vitreous can provide a real-time evaluation of floater size, movement, and morphology, to help clinicians target treatment and monitoring of symptomatic floaters. (Source: International Ophthalmology)
Source: International Ophthalmology - July 4, 2023 Category: Opthalmology Source Type: research
Changes in Density of Peripapillary and Intrapapillary Capillaries on OCT Angiography in Acute Retinal Necrosis Treated by Pharmacotherapy Alone without Surgery
CONCLUSION: In ARN, RPC and IPC were impaired even in eyes that were healed with medical treatment only without requiring surgical intervention and had no abnormal findings on ophthalmoscopic examination. This result suggests the presence of some degrees of optic neuropathy even in mild cases with good visual prognosis.PMID:37348115 | DOI:10.1080/09273948.2023.2221741 (Source: Ocular Immunology and Inflammation)
Source: Ocular Immunology and Inflammation - June 22, 2023 Category: Allergy & Immunology Authors: Kinya Tsubota Yoshihiko Usui Takeshi Kezuka Junichi Sakai Hiroshi Goto Source Type: research
Scanning Laser Ophthalmoscopy Demonstrates Disc and Peripapillary Strain During Horizontal Eye Rotation in Adults
We employed automated image analysis of scanning laser ophthalmoscopy (SLO) to investigate mechanical strains imposed on disc, and retinal and choroidal vessels during horizontal duction in adults. (Source: American Journal of Ophthalmology)
Source: American Journal of Ophthalmology - June 18, 2023 Category: Opthalmology Authors: Joseph Park, Sunghyuk Moon, Seongjin Lim, Joseph L. Demer Tags: Original Articles Source Type: research
A rare case of hyperpigmented torpedo maculopathy
CONCLUSION: A torpedo lesion with diffuse hyperpigmentation is an unusually rare presentation.PMID:37309137 | DOI:10.1177/11206721231182736 (Source: European Journal of Ophthalmology)
Source: European Journal of Ophthalmology - June 13, 2023 Category: Opthalmology Authors: Sai Prashanti Chitturi Ramesh Venkatesh Ashit Handa Rubble Mangla Jay Chhablani Source Type: research
A rare case of hyperpigmented torpedo maculopathy
CONCLUSION: A torpedo lesion with diffuse hyperpigmentation is an unusually rare presentation.PMID:37309137 | DOI:10.1177/11206721231182736 (Source: European Journal of Ophthalmology)
Source: European Journal of Ophthalmology - June 13, 2023 Category: Opthalmology Authors: Sai Prashanti Chitturi Ramesh Venkatesh Ashit Handa Rubble Mangla Jay Chhablani Source Type: research
Progression, reliability, predicting parameters and sample size calculations for quantitative fundus autofluorescence measures in < em > ABCA4 < /em > -related retinopathy
CONCLUSION: Under standardised settings with elaborated conditions towards operators and analysis to counterbalance variability, qAF imaging might be reliable, suitable for quantifying disease progression and constitutes a potential clinical surrogate marker in ABCA4-related retinopathy. Trial design based on patients' baseline characteristics and genotype has the potential to provide benefits regarding required cohort size and absolute number of visits.PMID:37286357 | DOI:10.1136/bjo-2022-322829 (Source: The British Journal of Ophthalmology)
Source: The British Journal of Ophthalmology - June 7, 2023 Category: Opthalmology Authors: Philipp L M üller Tim Treis Adnan Tufail Frank G Holz Source Type: research
Using high-density perimetry to explore new approaches for characterizing visual field defects
Vision Res. 2023 Jun 5;210:108259. doi: 10.1016/j.visres.2023.108259. Online ahead of print.ABSTRACTHigh-density threshold perimetry has found that conventional static threshold perimetry misses defects due to undersampling. However, high-density testing can be both slow and limited by normal fixational eye movements. We explored alternatives by studying displays of high-density perimetry results for angioscotomas in healthy eyes-areas of reduced sensitivity in the shadows of blood vessels. The right eyes of four healthy adults were tested with a Digital Light Ophthalmoscope that gathered retinal images while presenting vi...
Source: Vision Research - June 7, 2023 Category: Opthalmology Authors: I Mar ín-Franch H J Wyatt W H Swanson Source Type: research
Progression, reliability, predicting parameters and sample size calculations for quantitative fundus autofluorescence measures in < em > ABCA4 < /em > -related retinopathy
CONCLUSION: Under standardised settings with elaborated conditions towards operators and analysis to counterbalance variability, qAF imaging might be reliable, suitable for quantifying disease progression and constitutes a potential clinical surrogate marker in ABCA4-related retinopathy. Trial design based on patients' baseline characteristics and genotype has the potential to provide benefits regarding required cohort size and absolute number of visits.PMID:37286357 | DOI:10.1136/bjo-2022-322829 (Source: The British Journal of Ophthalmology)
Source: The British Journal of Ophthalmology - June 7, 2023 Category: Opthalmology Authors: Philipp L M üller Tim Treis Adnan Tufail Frank G Holz Source Type: research
Using high-density perimetry to explore new approaches for characterizing visual field defects
Vision Res. 2023 Jun 5;210:108259. doi: 10.1016/j.visres.2023.108259. Online ahead of print.ABSTRACTHigh-density threshold perimetry has found that conventional static threshold perimetry misses defects due to undersampling. However, high-density testing can be both slow and limited by normal fixational eye movements. We explored alternatives by studying displays of high-density perimetry results for angioscotomas in healthy eyes-areas of reduced sensitivity in the shadows of blood vessels. The right eyes of four healthy adults were tested with a Digital Light Ophthalmoscope that gathered retinal images while presenting vi...
Source: Vision Research - June 7, 2023 Category: Opthalmology Authors: I Mar ín-Franch H J Wyatt W H Swanson Source Type: research
Toxicological safety assessment of AP ‐Bio®, a standardized extract of Andrographis paniculata in Sprague Dawley rats
The objective of the present study was to assess the safety of AP-Bio ®, a standardizedA. paniculata extract in Sprague Dawley rats by following the Organisation for Economic Cooperation and Development (OECD) test guidelines of acute and 90-day repeated dose sub-chronic toxicity studies. AP-Bio ® did not show any treatment-related clinical signs of toxicity or mortality during the 14-day observation period in animals tested in the single-dose acute oral toxicity study up to a dose of 5000 mg/kg body weight. In the 90-day repeated dose sub-chronic oral toxicity study, no treatment-relate d adverse clinical signs were o...
Source: Journal of Applied Toxicology - June 4, 2023 Category: Toxicology Authors: Sasi Kumar Murugan,
Bharathi Bethapudi,
Amara Nageswara Rao,
Joseph Joshua Allan,
Deepak Mundkinajeddu,
Prashanth D'Souza Tags: RESEARCH ARTICLE Source Type: research
