How is the genome like an open book? New research shows cells' 'library system'
(New York University) The organization of the human genome relies on physics of different states of matter - such as liquid and solid. The findings reveal how the physical nature of the genome changes as cells transform to serve specific functions and point to new ways to potentially better understand disease and to create improved therapies for cancer and genetic disorders. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - June 2, 2021 Category: International Medicine & Public Health Source Type: news

How news coverage affects public trust in science
(Annenberg Public Policy Center of the University of Pennsylvania) News media reports about scientific failures that do not recognize the self-correcting nature of science can damage public perceptions of trust and confidence in scientific work, according to findings of a study by researchers at the Annenberg Public Policy Center of the University of Pennsylvania and the University at Buffalo, the State University of New York. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - June 1, 2021 Category: International Medicine & Public Health Source Type: news

Non-parents expand 'facial dexterity' in caring for infants among primates
(New York University) Non-parents expand the range of their facial expressions in caring for infants among primates. The study shows the ability, among non-relatives, to both decipher facial expressions and to be attuned to others' emotional states, revealing the evolutionary nature of communication. (Source: EurekAlert! - Social and Behavioral Science)
Source: EurekAlert! - Social and Behavioral Science - May 26, 2021 Category: International Medicine & Public Health Source Type: news

RYBREVANTTM (amivantamab-vmjw) Receives FDA Approval as the First Targeted Treatment for Patients with Non-Small Cell Lung Cancer with EGFR Exon 20 Insertion Mutations
May 21, 2021 (HORSHAM, P.A.) – The Janssen Pharmaceutical Companies of Johnson & Johnson announced today the U.S. Food and Drug Administration (FDA) has granted the accelerated approval of RYBREVANTTM (amivantamab-vmjw) for the treatment of adult patients with locally advanced or metastatic non-small cell lung cancer (NSCLC) with epidermal growth factor receptor (EGFR) exon 20 insertion mutations, as detected by an FDA-approved test, whose disease has progressed on or after platinum-based chemotherapy.[1] RYBREVANTTM is the first fully-human, bispecific antibody approved for the treatment of patients with NSCLC that ...
Source: Johnson and Johnson - May 21, 2021 Category: Pharmaceuticals Tags: Innovation Source Type: news

Modeling can predict mutation " hotspots " and antibody escapers in SARS-CoV-2 spike protein
(New York University) A new study from the Centers for Genomics and Systems Biology at New York University and NYU Abu Dhabi uses computational modeling to assess the biological significance of spike protein mutations, uncovering versions of the virus that bind more tightly or resist antibodies and offering a promising public health surveillance tool. (Source: EurekAlert! - Biology)
Source: EurekAlert! - Biology - May 19, 2021 Category: Biology Source Type: news

NYU Abu Dhabi researchers develop non-contact probe to analyze single cells within tumors
(New York University) NYU Abu Dhabi (NYUAD) researchers have developed a special noncontact multi-physics probe (NMP) that enables them to collect cytoplasmic samples from single tumor cells without disrupting their spatial configurations in the original tissue. As a result, the NMP will facilitate advanced studies that could improve the current understanding of the basic building blocks of diseases, including cancer and Alzheimer's, and lead to the development of new therapies. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - May 19, 2021 Category: Cancer & Oncology Source Type: news

How Juul Got Vaporized
On June 7, North Carolina attorney general Josh Stein will enter a Durham courtroom with a mission: proving that the e-cigarette company Juul Labs purposely targeted teenagers with its nicotine-rich products. If Stein—who in 2019 became the first state attorney general in the U.S. to sue Juul—is successful, the vaping company may be in for a world of hurt. Hundreds of lawsuits against Juul, many of which were consolidated into multi-district litigation in California, are pushing allegations mirroring Stein’s. They claim Juul purposely designed its stylish, flash-drive-like devices and flavored nicotine e-...
Source: TIME: Health - May 17, 2021 Category: Consumer Health News Authors: Jamie Ducharme Tags: Uncategorized Excerpt feature Magazine Vaping Source Type: news

Losing an only child is more devastating than losing a spouse, according to study of Chinese parents
(New York University) Which wound cuts deeper: the loss of an only child or loss of a spouse? A new study led by researchers at NYU Rory Meyers College of Nursing and Fudan University suggests that Chinese parents find the loss of an only child to be approximately 1.3 times as psychologically distressing than the loss of a spouse. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - May 7, 2021 Category: International Medicine & Public Health Source Type: news

Even fractures in arm, wrist increase risk for future breaks in postmenopausal women
Current guidelines for managing osteoporosis specifically call out hip or spine fractures for increasing the risk for subsequent bone breaks. But anew UCLA-led study suggests that fractures in the arm, wrist, leg and other parts of the body should also set off alarm bells.A fracture, no matter the location, indicates a general tendency to break a bone in the future at a different location, said Dr. Carolyn Crandall, the study ’s lead author and a professor of medicine at theDavid Geffen School of Medicine at UCLA.“Current clinical guidelines have only been emphasizing hip and spine fractures, but our findings challenge...
Source: UCLA Newsroom: Health Sciences - May 5, 2021 Category: Universities & Medical Training Source Type: news

Study: New York City nurses experienced anxiety, depression during first wave of COVID-19
(New York University) New York nurses caring for COVID-19 patients during the first wave of the pandemic experienced anxiety, depression, and illness--but steps their hospitals took to protect them and support from their coworkers helped buffer against the stressful conditions, according to a study led by researchers at NYU Rory Meyers College of Nursing. (Source: EurekAlert! - Infectious and Emerging Diseases)
Source: EurekAlert! - Infectious and Emerging Diseases - April 29, 2021 Category: Infectious Diseases Source Type: news

Kratom use rare, but more common among people with opioid use disorder
(New York University) Less than one percent of people in the United States use kratom, a plant-based substance commonly used to manage pain and opioid withdrawal, according to a study published in the American Journal of Preventive Medicine. However, the use of kratom--which is legal but carries the risk of addiction and harmful side effects--is more prevalent among people who use other drugs, particularly those with opioid use disorder. (Source: EurekAlert! - Social and Behavioral Science)
Source: EurekAlert! - Social and Behavioral Science - April 29, 2021 Category: International Medicine & Public Health Source Type: news

Single-cell CRISPR technology deciphers role of chromatin accessibility in cancer
(New York Genome Center) Researchers in the lab of Neville Sanjana, PhD, at the New York Genome Center (NYGC) and New York University (NYU) have developed CRISPR-sciATAC, a novel integrative genetic screening platform that jointly captures CRISPR gene perturbations and single-cell chromatin accessibility genome-wide. The new method harnesses the programmability of the gene editing system CRISPR to knock-out nearly all chromatin-related genes in parallel, offering researchers deeper insights into the role of DNA accessibility in cancer and in rare diseases involving chromatin. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - April 29, 2021 Category: Cancer & Oncology Source Type: news

New approaches for teaching science remotely arise from the COVID-19 crisis
(New York University) A new paper on college science classes taught remotely points to teaching methods that enhance student communication and collaboration, offering a framework for enriching online instruction as the coronavirus pandemic continues to limit in-person courses. (Source: EurekAlert! - Biology)
Source: EurekAlert! - Biology - April 27, 2021 Category: Biology Source Type: news

Addressing the Impact of COVID-19 on Infants and Young Children
Children display dexterity during a free play session prior to the pandemic. Credit: BRACBy Erum MariamDHAKA, Bangladesh, Apr 26 2021 (IPS) Conventional wisdom is that the health of young children is not at great risk from COVID-19, but, in the Global South, the space constraints imposed on young children by the pandemic pose a significant risk to the stimulation on which brain development thrives. Early childhood development is further jeopardized by the pandemic’s impact on caregivers. A new early childhood development infrastructure has been built in Bangladesh by BRAC, the largest international development organizat...
Source: IPS Inter Press Service - Health - April 26, 2021 Category: International Medicine & Public Health Authors: Erum Mariam Tags: Aid Asia-Pacific Education Headlines Health Humanitarian Emergencies TerraViva United Nations Source Type: news

NYU Abu Dhabi researchers develop Micro-Fluidic Probe to isolate cancer spreading cells
(New York University) A team of researchers led by Assistant Professor of Mechanical and Biomedical Engineering and Principal Investigator at the NYU Abu Dhabi Mohammad A. Qasaimeh, have developed a new microfluidic system, called the Herringbone Microfluidic Probe (HB-MFP), that effectively isolates both CTCs and clusters of CTCs from blood samples of cancer patients for easier and more insightful analysis. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - April 19, 2021 Category: Cancer & Oncology Source Type: news