2019 RNA Biology Symposium (Day 1)
RNA biology has emerged as one of the most influential areas in modern biology and biomedicine. The discovery of numerous new classes of RNAs and their function in a wide spectrum of biological processes has revolutionized molecular biology and has profound implications for clinical sciences. Key areas of current research include the elucidation of RNA biogenesis and structure, the identification of functions for various classes of RNAs, establishing the role of RNA in disease and the exploration of RNA-based-and RNA-targeted therapies.
Organized by the CCR Initiative in RNA Biology, this symposium will bring together inte...
Source: Videocast - All Events - April 4, 2019 Category: General Medicine Tags: Upcoming Events Source Type: video
RNA degradation controls inflammation
NIH Director's Wednesday Afternoon Lecture Series
Dr. Akira is a director and special appointed professor of Immunology Frontier Research Center. He received his M.D. and Ph.D. from Osaka University. After two years of postdoctoral working in Department of Immunology, University of California at Berkeley, he started to study on IL-6 gene regulation and signaling in the Institute for Molecular and Cellular Biology, Osaka University, and cloned transcription factors, NF-IL6(C/EBP beta) and STAT3. He was a professor in Department of Biochemistry, Hyogo College of Medicine from 1996 to 1999, where he became involved in Toll-li...
Source: Videocast - All Events - March 26, 2019 Category: General Medicine Tags: Upcoming Events Source Type: video
NIH Director's Seminar: Imaging the nanoscale structure of endocytosis with correlative super-resolution light and electron microscopy
NIH Director's Seminar Series
The plasma membrane separates the cell ’ s interior from the outside world. The exchange of signals and material across this barrier is regulated by a multitude of channels, transporters, receptors, and trafficking organelles. Mapping the molecular structure and dynamics of the plasma membrane is key to understanding how human cells function in health and malfunction in disease. Electron microscopy can produce high resolution images of the membrane. Historically, it has been challenging to locate and identify proteins within these images. Recently-developed super-resolution localization micr...
Source: Videocast - All Events - February 28, 2019 Category: General Medicine Tags: Upcoming Events Source Type: video
NIDCR Grand Rounds: Mechanoregeneration via Biomaterials
NIDCR Clinical Research Fellowship Grand Rounds
Dr. David Mooney ’ s research is based on the question, “ How do mammalian cells receive information from the materials in their environment? ” By using the tools of bioengineering and cell and molecular biology, he studies the mechanisms by which chemical or mechanical signals are sensed by cells, and how these signals alter cellular proliferation and specialization to either promote tissue growth or destruction. His research results inform the design and synthesis of new biomaterials that regulate the gene expression of interacting cells for a variety of tissue engine...
Source: Videocast - All Events - February 25, 2019 Category: General Medicine Tags: Upcoming Events Source Type: video
Everything you wanted to know about microtubules but were afraid to ask
NIH Director's Seminar Series
Dr. Roll-Mecak will discuss the research of the Laboratory of Cell Biology and Biophysics Section, NINDS. The title of her talk is " Everything you wanted to know about microtubules but were afraid to ask " .
In addition to providing structural support, microtubules form a complex and dynamic intracellular " highway " that delivers molecular cargo from one end of the cell to another - which in the case of neuronal cells can span several feet. Given the continually changing cell physiology, this delivery system undergoes constant remodeling as cargo is transported to different destinations with...
Source: Videocast - All Events - January 31, 2019 Category: General Medicine Tags: Upcoming Events Source Type: video
Natural products and Pain: The Search for Novel Nonopioid Analgesics
Discussion will focus on how to identify promising leads based on traditional medicine; discover and identify active natural products; and characterize the mechanisms through which they act.
The workshop is chaired by David Julius, Ph.D., professor and chair of the physiology department at the University of California-San Francisco School of Medicine. Dr. Julius is an expert of international renown on the molecular biology of how signals are received and transmitted by the nervous system, including in touch and pain.Air date: 2/6/2019 8:30:00 AM (Source: Videocast - All Events)
Source: Videocast - All Events - January 28, 2019 Category: General Medicine Tags: Upcoming Events Source Type: video
Metabolic Constraints of Tumor Growth
NCI ’ s Center for Cancer Research (CCR) Grand Rounds
Matthew Vander Heiden is an Associate Professor in the Department of Biology at the Massachusetts Institute of Technology and Associate Director of the Koch Institute for Integrative Cancer Research. He is also an HHMI Faculty Scholar, an Institute Member of the Broad Institute of Harvard and MIT, and an Instructor of Medicine at the Dana-Farber Cancer Institute and Harvard Medical School. Dr. Vander Heiden received his M.D. and Ph.D. degree from the University of Chicago. He also completed clinical training in internal medicine and medical oncology at the Brigham and...
Source: Videocast - All Events - December 4, 2018 Category: General Medicine Tags: Upcoming Events Source Type: video
Structure and Signaling Mechanisms of G Protein-Coupled and b-Arrestin-Biased Chemokine Receptors
IIG Seminar
Most chemokine receptors are G Protein-Coupled Receptors (GPCRs), and are best known for their role in controlling cell migration in the context of immune system function. They are also implicated in many diseases particularly inflammatory diseases as well as cancer and HIV, making them important therapeutic targets. Recent structural and biophysical studies have revealed that the recognition interface between chemokines and receptors is very large and characterized by more complex epitopes than previously believed. In this presentation, our current understanding of how chemokines bind and activate their recept...
Source: Videocast - All Events - November 29, 2018 Category: General Medicine Tags: Upcoming Events Source Type: video
How mothers give the best and enough mitochondria
NIH Directors Seminar Series
Dr. Xu ’ s Laboratory of Molecular Genetics, Systems Biology Center, NHLBI is interested in the basic mechanism guiding the transmission of our second genome- mitochondrial DNA. Mutations in mitochondrial genome have emerged as important factors compromising human health. Although mitochondrial genome is prone to accumulating mutations due to the high spontaneous mutation frequency and a lack of repair mechanisms, the crippling mitochondrial mutation is exceedingly rare in populations. It is puzzling how mothers are able to restrict the transmission of damaging mutations to the next generatio...
Source: Videocast - All Events - October 10, 2018 Category: General Medicine Tags: Upcoming Events Source Type: video
NIH Director's Seminar Series
NIH Directors Seminar Series
Dr. Xu ’ s Laboratory of Molecular Genetics, Systems Biology Center, NHLBI is interested in the basic mechanism guiding the transmission of our second genome- mitochondrial DNA. Mutations in mitochondrial genome have emerged as important factors compromising human health. Although mitochondrial genome is prone to accumulating mutations due to the high spontaneous mutation frequency and a lack of repair mechanisms, the crippling mitochondrial mutation is exceedingly rare in populations. It is puzzling how mothers are able to restrict the transmission of damaging mutations to the next generatio...
Source: Videocast - All Events - October 9, 2018 Category: General Medicine Tags: Upcoming Events Source Type: video
Sexual & Gender Minority Health Research: (1) Informatics and Health Policy: Building the Evidence to Improve Transgender Health and (2) Reducing Health Disparities Among Sexual and Gender Minority Individuals
The NIH Sexual& Gender Minority Research Office is pleased to announce our inaugural Investigator Award Program. The Sexual and Gender Minority (SGM) Investigator Award Program was developed to recognize early-stage investigators who have made substantial, outstanding research contributions in areas related to SGM health and who are poised to become future leaders or are already leading the field of SGM health research.
Dr. Jesse Ehrenfeld is a board-certified physician anesthesiologist with a background in clinical research, advocacy, and health care policy. He currently is a professor at the Vanderbilt University School ...
Source: Videocast - All Events - September 18, 2018 Category: General Medicine Tags: Upcoming Events Source Type: video
The Evolution of Metastatic Prostate Cancer Under Treatment Pressure: Anticipating and Exploiting Pathways of Resistance
NCI ’ s Center for Cancer Research (CCR) Grand Rounds
Dr. Peter Nelson is a Member in the Divisions of Human Biology and Clinical Research, Fred Hutchinson Cancer Research Center and Professor of Medicine in the Division of Medical Oncology at the University of Washington. He received an M.D. degree and completed residency training at the University of Kansas, received post-doctoral training at the National Institutes of Health through a biotechnology fellowship, and completed clinical medical oncology training at the Hutchinson Cancer Center and University of Washington.
Dr. Nelson has an active clinical practice caring...
Source: Videocast - All Events - September 4, 2018 Category: General Medicine Tags: Upcoming Events Source Type: video
20th Annual Norman P. Salzman Memorial Award and Symposium in Virology
The Dr. Norman P. Salzman Memorial Fund was established in 1999 to present the annual Norman P. Salzman Memorial Symposium and Award in Virology to an outstanding Postdoctoral Fellow, Research Fellow or Clinical Fellow working in the field of virology at the NIH, the Center for Biologics Evaluation and Research at the U.S. Food and Drug Administration or Leidos community. The Symposium and Award are hosted by the FNIH and the NIH Virology Interest Group. The symposium highlights current research of eminent extramural and NIH intramural virologists.
The Fund was established by Dr. Salzman ’ s family, colleagues and friend...
Source: Videocast - All Events - June 26, 2018 Category: General Medicine Tags: Upcoming Events Source Type: video
The ATP synthase: a gifted protein that keeps on giving
NIH Director's Seminar Series
ATP synthases produce most of the ATP that sustains living cells – that is, in a human body, over 150 pounds of ATP per day! Found in the membranes of mitochondria, chloroplasts and bacteria, these paradigmatic enzymes harness the electrochemical energy that results from nutrient metabolism or light harvesting to power a turbine-like mechanism, through which they recycle the two by-products of ATP hydrolysis, ADP and inorganic phosphate, into brand-new ATP. Dr. Faraldo-Gomez will discuss recent breakthroughs in the structural characterization of these systems at the molecular and supramolecu...
Source: Videocast - All Events - June 18, 2018 Category: General Medicine Tags: Upcoming Events Source Type: video
2018 Lipsett Lecture: " Oncofertility: From Bench to Bedside to Babies "
The Lipsett Lecture is an annual lecture held by NICHD to honor Dr. Mortimer B. Lipsett, Director of the National Institute of Arthritis, Diabetes, and Digestive and Kidney Diseases, National Institutes of Health (NIH), who died of cancer on November 10, 1985 at the Clinical Center. This year's speaker will be Dr. Teresa K. Woodruff, Dean and Associate Provost for Graduate Education in The Graduate School at Northwestern University and Thomas J. Watkins Professor of Obstetrics& Gynecology, the Vice Chair for Research and the Chief of the Division of Reproductive Science in Medicine in the Department of Obstetrics and Gynec...
Source: Videocast - All Events - June 12, 2018 Category: General Medicine Tags: Upcoming Events Source Type: video
