Could a Spoonful of Sugar Be a Medicine?
Glycans glow red, yellow, and green in this image of a zebrafish embryo’s jaw. Credit: Carolyn Bertozzi, University of California, Berkeley.
Large sugar molecules called glycans coat every cell in our bodies. They can also be found inside and between cells, and they are important for many biological processes, including how our cells interact with one another and with pathogens. For example, glycans on red blood cells determine blood type, and those on the cells of organs determine whether a person can receive a transplant from a particular donor. Scientists have only begun to explore sugars’ complexities and po...
Source: Biomedical Beat Blog - National Institute of General Medical Sciences - September 29, 2021 Category: Research Authors: Chrissa Chverchko Tags: Chemistry, Biochemistry and Pharmacology Glycobiology Research Roundup Source Type: blogs
Alaska Delegation Targets Cruise Ship Protectionism
Colin GrabowAfter decades of maritime protectionism diverting Alaska ‐bound cruise ships (and tourist dollars) to Canadian ports, some measure of common sense may finally prevail. Earlier this week Sen. Lisa Murkowski (R-AK)announced her forthcoming introduction of legislation to ease the burden of the Passenger Vessel Services Act (PVSA) on Alaska. In so doing, Murkowski will become the second member of Alaska ’s congressional delegation to target the PVSA in recent months, with Rep. Don Youngputting forth a separate bill in July to loosen the law ’s shackles.It ’s welcome news. Legislation to pare ba...
Source: Cato-at-liberty - September 17, 2021 Category: American Health Authors: Colin Grabow Source Type: blogs
Dismissed for too long: recommendations to improve migraine care in the UK
This report found a wide range of issues with migraine healthcare including slow or no diagnosis and lack of access to specialist care. It sets out the action needed from government, healthcare systems and other oganisations to give everyone living with migraine in the UK the support they need.ReportPress release (Source: Health Management Specialist Library)
Source: Health Management Specialist Library - September 6, 2021 Category: UK Health Authors: The King ' s Fund Library Tags: Public health and health inequalities Source Type: blogs
Reading Aloud without a Mask, Olfactory Bulbs, Omega Variant
Conclusion and recommendation:" Ineligibility because of age and lack of vaccination contribute to persistent elevated risk for outbreaks in schools, especially as new SARS-CoV-2 variants emerge. However, implementation of multiple prevention strategies within schools can mitigate this risk. "Olfactory Bulbs Speaking of smell,over 20 papers show MRI signal abnormalities in the olfactory bulbs of COVID-19 patients with anosmia (loss of smell). This isn ' t new, but anosmia has been reported inbreakthroughcasesas well. The images below show some resolution in a patient from time 1 to time 2.Magnetic Resonance Imaging Al...
Source: The Neurocritic - August 31, 2021 Category: Neuroscience Authors: The Neurocritic Source Type: blogs
The 9 Trends Shaping the Future of Pharma
The drug sends a message to a caregiver after the patient swallowed it. The doctor prescribes virtual reality treatments for migraines. Do you think it is science fiction? You are mistaken. Just let me familiarize you with the top 10 trends shaping the future of pharma.
And if you want to have a more in-depth analysis of the topic, read our related ebook, Technologies Shaping the Future of Pharma!
Technologies Shaping the Future of Pharma
We designed this e-book to serve as a collection of relevant examples, best practic...
Source: The Medical Futurist - August 26, 2021 Category: Information Technology Authors: berci.mesko Tags: Future of Medicine Future of Pharma 3d printing artificial intelligence augmented reality digital health Innovation nanotechnology Personalized medicine pharmacology virtual reality VR gc4 pharmacies pharmacogenetics Source Type: blogs
The 10 Trends Shaping the Future of Pharma
The drug sends a message to a caregiver after the patient swallowed it. The doctor prescribes virtual reality treatments for migraines. Do you think it is science fiction? You are mistaken.
The pharma industry has taken a big swung into digital transformation. All participants invest in digital health topics. But as with all trending issues, and there is a lot of fuss that is hard to see through. As the medical community increasingly acknowledges the importance of digital health, the cultural shift we so often talk about is still a way to go. To change that, the first step is always getting to know what’s coming.
...
Source: The Medical Futurist - August 26, 2021 Category: Information Technology Authors: berci.mesko Tags: Future of Medicine Future of Pharma 3d printing artificial intelligence augmented reality digital health Innovation nanotechnology Personalized medicine pharmacology virtual reality VR gc4 pharmacies pharmacogenetics Source Type: blogs
When living with pain is too hard
Living with persistent pain can be really hard, and clinicians, family and the person with pain can be worried about suicidal thoughts and possible actions. There’s good reason to be concerned, too, as a recent study from the 2012 Canadian Community Health Survey shows.
Grocott, Sommer and El-Gabalawy (2021) used the data obtained from this Canadian Health Survey to explore the relationships between pain intensity and suicidality in people with arthritis, migraines and low back pain.
The first question is how many people in the overall population involved in this study had any of the three diagnostic groups &...
Source: HealthSkills Weblog - August 1, 2021 Category: Anesthesiology Authors: BronnieLennoxThompson Tags: Chronic pain Coping strategies Low back pain Pain conditions Professional topics Research biopsychosocial Clinical reasoning Health Suicidal thoughts Therapeutic approaches Source Type: blogs
University of Freiburg – Research Assistant position
We are seeking a full-time or part time research assistant to support and manage research projects at the Department of Neurology. We study how the brain works and how it recovers from damage. Clinical and neuropsychological behavioural tests (eg: language, spatial processing, praxis, spatial perception, memory) are correlated with brain anatomy and function (eg: fMRI, rsfMRI, DTI, sMRT, PET, TMS) in group studies of patients (mainly stroke, Parkinson ’s disease and migraine). In a large scale project carefully selected stroke patients (first ever stroke, single ischemic lesion) are prospectively tested during acute stag...
Source: Talking Brains - July 19, 2021 Category: Neuroscience Authors: Greg Hickok Source Type: blogs
University of Freiburg – Research Assistant position
We are seeking a full-time or part time research assistant to support and manage researchprojects at the Department of Neurology. We study how the brain works and how it recoversfrom damage. Clinical and neuropsychological behavioural tests (eg: language, spatialprocessing, praxis, spatial perception, memory) are correlated with brain anatomy andfunction (eg: fMRI, rsfMRI, DTI, sMRT, PET, TMS) in group studies of patients (mainlystroke, Parkinson ’s disease and migraine). In a large scale project carefully selected strokepatients (first ever stroke, single ischemic lesion) are prospectively tested during acute stageand f...
Source: Talking Brains - July 19, 2021 Category: Neuroscience Authors: Greg Hickok Source Type: blogs
Migraines Halved By Simple Dietary Change (M)
People eating this diet experienced 40 percent reductions in total headache hours, overall headache days and severity of headaches. (Source: PsyBlog | Psychology Blog)
Source: PsyBlog | Psychology Blog - July 9, 2021 Category: Psychiatry & Psychology Authors: Jeremy Dean Tags: Migraine subscribers-only Source Type: blogs
Fight Aging! Newsletter, June 21st 2021
This study showed that the leakage of this mitochondrial nucleic material may occur as a result of mitochondrial dysfunction, which may involve genetic mutations in genes encoding mitochondrial proteins or incomplete degradation of mitochondrial dsDNA in the lysosome - which is a 'degradation factory' of the cell. Upon the leakage into the cytoplasm, this undegraded dsDNA is detected by a 'foreign' DNA sensor of the cytoplasm (IFI16) which then triggers the upregulation of mRNAs encoding for inflammatory proteins."
Using a PD zebrafish model (gba mutant), the researchers demonstrated that a combination of PD-like ph...
Source: Fight Aging! - June 20, 2021 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
Details on the Failed Phase 3 Trial of the resTORbio mTORC1 Inhibitor
The short version of the story regarding the failure of resTORbio's phase 3 trial of an mTORC1 inhibitor targeting immune function and influenza infection in old people is that the FDA forced a last minute change of the phase 3 endpoint from the phase 2 endpoint of a reduction in clinically confirmed infections to a more nebulous outcome of whether or not people reported feeling better. Which is far from the worst offense that FDA staff have committed in the course of hindering the adoption of new medical technologies, but it is illustrative of the obstacle that regulators pose. We can all speculate as to what was going on...
Source: Fight Aging! - June 16, 2021 Category: Research Authors: Reason Tags: Politics and Legislation Source Type: blogs
Growing backlash against the FDA approval of unproven Alzheimer ’s treatment Aduhelm, by Biogen
ICER Issues Statement on the FDA’s Approval of Aducanumab for Alzheimer’s Disease (Institute for Clinical and Economic Review):
The Institute for Clinical and Economic Review (ICER) believes that the FDA, in approving aducanumab (Aduhelm™, Biogen) for the treatment of Alzheimer’s disease, has failed in its responsibility to protect patients and families from unproven treatments with known harms.
Our review of the evidence was concordant with that of many independent experts: current evidence is insufficient to demonstrate that aducanumab benefits patients. The avenue forward has seemed clear: another study would be...
Source: SharpBrains - June 14, 2021 Category: Neuroscience Authors: SharpBrains Tags: Brain/ Mental Health aducanumab Aduhelm Alzheimer’s Disease Alzheimer’s disease treatment amyloid amyloid plaques amyloid-related imaging abnormalities ARIA Biogen brain swelling clinical benefit FDA ICER Janet Woodcock N Source Type: blogs
How To Know It ’s Time For A Digital Detox
It’s no secret that technology has had a monumental impact on our society and our daily lives in an incredibly short amount of time. Google is only 22 years old, Youtube is 16 years old, and Facebook is about 17 years old. Some people may fondly remember simpler times before these tech giants came about, while other people simply cannot imagine life without them. Either way, it’s obvious that our reliance on technology isn’t going anywhere, so it’s important to know how to be able to tell when it’s time to take a break from your electronic devices.
Mental Health Decline
If you are experiencing a decline in ...
Source: PickTheBrain | Motivation and Self Improvement - May 18, 2021 Category: Consumer Health News Authors: Amber Healy Tags: depression featured internet culture psychology self-improvement success working from home digital detox mental health pickthebrain technology Source Type: blogs
15 Self Care Ideas That Fit Into Your Lunch Break
Self care is important for your physical, mental, and emotional health…but sometimes there just isn’t a lot of time for indulging in self care activities when you also have a job, a family, chores, etc.
So while self care might be one of the first things to go when your to-do list stacks up, the times when you are busy and overwhelmed are actually when you could benefit from self care the most.
That’s why I learned that self care is all about balance! Don’t try to overextend yourself and do all of the self care activities you can think of every single day. It’s just not realistic.
Instead, try comm...
Source: PickTheBrain | Motivation and Self Improvement - May 17, 2021 Category: Consumer Health News Authors: selfcareseeker Tags: creativity featured happiness health and fitness motivation productivity tips psychology self-improvement good habits mental health pickthebrain self care self improvement Source Type: blogs
