A review of the impact of decision heuristics on calorie underestimation and the implications for unhealthy eating
Ziang Wang, Toritseju Begho Nutrition & Food Science, Vol. ahead-of-print, No. ahead-of-print, pp.- The global rise in obesity can be closely linked to excessive calorie consumption and misperceptions regarding food intake. Thus, the purpose of this paper is to review the existing literature to have a better understanding how heuristic cues – mental shortcuts used for decision-making – impact calorie underestimation and consequently lead to unhealthy eating habits.A search was conducted across multiple databases with priority given to studies in developed countries that provided insights into the cognitive process...
Source: Nutrition and Food Science - March 9, 2024 Category: Nutrition Authors: Ziang Wang Toritseju Begho Source Type: research

Should Glucokinase be Given a Chance in Diabetes Therapeutics? A Clinical-Pharmacological Review of Dorzagliatin and Lessons Learned So Far
AbstractDespite advances in the management of type 2 diabetes mellitus (T2DM), one-third of patients with diabetes do not achieve the desired glycemic goal. Considering this inadequacy, many agents that activate glucokinase have been investigated over the last two decades but were withdrawn before submission for marketing permission. Dorzagliatin is the first glucokinase activator that has been granted approval for T2DM, only in China. As overstimulation of glucokinase is linked with pathophysiological disturbances such as fatty liver and cardiovascular issues and a loss of therapeutic efficacy with time. This review aims ...
Source: Clinical Drug Investigation - March 9, 2024 Category: Drugs & Pharmacology Source Type: research

Analytical assessment of clinical sensitivity and specificities of pharmaceutical rapid SARS-CoV-2 detection nasopharyngeal swab testing kits in Pakistan
Braz J Biol. 2024 Mar 4;84:e265550. doi: 10.1590/1519-6984.265550. eCollection 2024.ABSTRACTDespite of the global unity against COVID-19 pandemic, the threat of SARS-CoV-2 variants on the lives of human being is still not over. SARS-CoV-2 pandemic has urged the need of rapid viral detection at earliest. To cope with gradually expanding scenario of SARS-CoV-2, accurate diagnosis is extremely crucial factor which should be noticed by international health organizations. Limited research followed by sporadic marketing of SARS-CoV-2 rapid pharmaceutical detection kits raises critical questions against quality assurance and qual...
Source: Braz J Biol - March 7, 2024 Category: Biology Authors: U Saeed R Uppal A A Khan M R Uppal Z Z Piracha S R Uppal Source Type: research

Analytical assessment of clinical sensitivity and specificities of pharmaceutical rapid SARS-CoV-2 detection nasopharyngeal swab testing kits in Pakistan
Braz J Biol. 2024 Mar 4;84:e265550. doi: 10.1590/1519-6984.265550. eCollection 2024.ABSTRACTDespite of the global unity against COVID-19 pandemic, the threat of SARS-CoV-2 variants on the lives of human being is still not over. SARS-CoV-2 pandemic has urged the need of rapid viral detection at earliest. To cope with gradually expanding scenario of SARS-CoV-2, accurate diagnosis is extremely crucial factor which should be noticed by international health organizations. Limited research followed by sporadic marketing of SARS-CoV-2 rapid pharmaceutical detection kits raises critical questions against quality assurance and qual...
Source: Braz J Biol - March 7, 2024 Category: Biology Authors: U Saeed R Uppal A A Khan M R Uppal Z Z Piracha S R Uppal Source Type: research

Analytical assessment of clinical sensitivity and specificities of pharmaceutical rapid SARS-CoV-2 detection nasopharyngeal swab testing kits in Pakistan
Braz J Biol. 2024 Mar 4;84:e265550. doi: 10.1590/1519-6984.265550. eCollection 2024.ABSTRACTDespite of the global unity against COVID-19 pandemic, the threat of SARS-CoV-2 variants on the lives of human being is still not over. SARS-CoV-2 pandemic has urged the need of rapid viral detection at earliest. To cope with gradually expanding scenario of SARS-CoV-2, accurate diagnosis is extremely crucial factor which should be noticed by international health organizations. Limited research followed by sporadic marketing of SARS-CoV-2 rapid pharmaceutical detection kits raises critical questions against quality assurance and qual...
Source: Braz J Biol - March 7, 2024 Category: Biology Authors: U Saeed R Uppal A A Khan M R Uppal Z Z Piracha S R Uppal Source Type: research

Analytical assessment of clinical sensitivity and specificities of pharmaceutical rapid SARS-CoV-2 detection nasopharyngeal swab testing kits in Pakistan
Braz J Biol. 2024 Mar 4;84:e265550. doi: 10.1590/1519-6984.265550. eCollection 2024.ABSTRACTDespite of the global unity against COVID-19 pandemic, the threat of SARS-CoV-2 variants on the lives of human being is still not over. SARS-CoV-2 pandemic has urged the need of rapid viral detection at earliest. To cope with gradually expanding scenario of SARS-CoV-2, accurate diagnosis is extremely crucial factor which should be noticed by international health organizations. Limited research followed by sporadic marketing of SARS-CoV-2 rapid pharmaceutical detection kits raises critical questions against quality assurance and qual...
Source: Braz J Biol - March 7, 2024 Category: Biology Authors: U Saeed R Uppal A A Khan M R Uppal Z Z Piracha S R Uppal Source Type: research

Analytical assessment of clinical sensitivity and specificities of pharmaceutical rapid SARS-CoV-2 detection nasopharyngeal swab testing kits in Pakistan
Braz J Biol. 2024 Mar 4;84:e265550. doi: 10.1590/1519-6984.265550. eCollection 2024.ABSTRACTDespite of the global unity against COVID-19 pandemic, the threat of SARS-CoV-2 variants on the lives of human being is still not over. SARS-CoV-2 pandemic has urged the need of rapid viral detection at earliest. To cope with gradually expanding scenario of SARS-CoV-2, accurate diagnosis is extremely crucial factor which should be noticed by international health organizations. Limited research followed by sporadic marketing of SARS-CoV-2 rapid pharmaceutical detection kits raises critical questions against quality assurance and qual...
Source: Braz J Biol - March 7, 2024 Category: Biology Authors: U Saeed R Uppal A A Khan M R Uppal Z Z Piracha S R Uppal Source Type: research

Analytical assessment of clinical sensitivity and specificities of pharmaceutical rapid SARS-CoV-2 detection nasopharyngeal swab testing kits in Pakistan
Braz J Biol. 2024 Mar 4;84:e265550. doi: 10.1590/1519-6984.265550. eCollection 2024.ABSTRACTDespite of the global unity against COVID-19 pandemic, the threat of SARS-CoV-2 variants on the lives of human being is still not over. SARS-CoV-2 pandemic has urged the need of rapid viral detection at earliest. To cope with gradually expanding scenario of SARS-CoV-2, accurate diagnosis is extremely crucial factor which should be noticed by international health organizations. Limited research followed by sporadic marketing of SARS-CoV-2 rapid pharmaceutical detection kits raises critical questions against quality assurance and qual...
Source: Braz J Biol - March 7, 2024 Category: Biology Authors: U Saeed R Uppal A A Khan M R Uppal Z Z Piracha S R Uppal Source Type: research

Analytical assessment of clinical sensitivity and specificities of pharmaceutical rapid SARS-CoV-2 detection nasopharyngeal swab testing kits in Pakistan
Braz J Biol. 2024 Mar 4;84:e265550. doi: 10.1590/1519-6984.265550. eCollection 2024.ABSTRACTDespite of the global unity against COVID-19 pandemic, the threat of SARS-CoV-2 variants on the lives of human being is still not over. SARS-CoV-2 pandemic has urged the need of rapid viral detection at earliest. To cope with gradually expanding scenario of SARS-CoV-2, accurate diagnosis is extremely crucial factor which should be noticed by international health organizations. Limited research followed by sporadic marketing of SARS-CoV-2 rapid pharmaceutical detection kits raises critical questions against quality assurance and qual...
Source: Braz J Biol - March 7, 2024 Category: Biology Authors: U Saeed R Uppal A A Khan M R Uppal Z Z Piracha S R Uppal Source Type: research

Analytical assessment of clinical sensitivity and specificities of pharmaceutical rapid SARS-CoV-2 detection nasopharyngeal swab testing kits in Pakistan
Braz J Biol. 2024 Mar 4;84:e265550. doi: 10.1590/1519-6984.265550. eCollection 2024.ABSTRACTDespite of the global unity against COVID-19 pandemic, the threat of SARS-CoV-2 variants on the lives of human being is still not over. SARS-CoV-2 pandemic has urged the need of rapid viral detection at earliest. To cope with gradually expanding scenario of SARS-CoV-2, accurate diagnosis is extremely crucial factor which should be noticed by international health organizations. Limited research followed by sporadic marketing of SARS-CoV-2 rapid pharmaceutical detection kits raises critical questions against quality assurance and qual...
Source: Braz J Biol - March 7, 2024 Category: Biology Authors: U Saeed R Uppal A A Khan M R Uppal Z Z Piracha S R Uppal Source Type: research

Analytical assessment of clinical sensitivity and specificities of pharmaceutical rapid SARS-CoV-2 detection nasopharyngeal swab testing kits in Pakistan
Braz J Biol. 2024 Mar 4;84:e265550. doi: 10.1590/1519-6984.265550. eCollection 2024.ABSTRACTDespite of the global unity against COVID-19 pandemic, the threat of SARS-CoV-2 variants on the lives of human being is still not over. SARS-CoV-2 pandemic has urged the need of rapid viral detection at earliest. To cope with gradually expanding scenario of SARS-CoV-2, accurate diagnosis is extremely crucial factor which should be noticed by international health organizations. Limited research followed by sporadic marketing of SARS-CoV-2 rapid pharmaceutical detection kits raises critical questions against quality assurance and qual...
Source: Braz J Biol - March 7, 2024 Category: Biology Authors: U Saeed R Uppal A A Khan M R Uppal Z Z Piracha S R Uppal Source Type: research

Analytical assessment of clinical sensitivity and specificities of pharmaceutical rapid SARS-CoV-2 detection nasopharyngeal swab testing kits in Pakistan
Braz J Biol. 2024 Mar 4;84:e265550. doi: 10.1590/1519-6984.265550. eCollection 2024.ABSTRACTDespite of the global unity against COVID-19 pandemic, the threat of SARS-CoV-2 variants on the lives of human being is still not over. SARS-CoV-2 pandemic has urged the need of rapid viral detection at earliest. To cope with gradually expanding scenario of SARS-CoV-2, accurate diagnosis is extremely crucial factor which should be noticed by international health organizations. Limited research followed by sporadic marketing of SARS-CoV-2 rapid pharmaceutical detection kits raises critical questions against quality assurance and qual...
Source: Braz J Biol - March 7, 2024 Category: Biology Authors: U Saeed R Uppal A A Khan M R Uppal Z Z Piracha S R Uppal Source Type: research

Evaluating the 6-month formulation of paliperidone palmitate: a twice-yearly injectable treatment for schizophrenia in adults
Expert Rev Neurother. 2024 Apr;24(4):325-332. doi: 10.1080/14737175.2024.2325655. Epub 2024 Mar 6.ABSTRACTINTRODUCTION: Paliperidone Palmitate is the only antipsychotic that has been developed in three different intramuscular long-acting injectable (LAI) dosing regimen: monthly (PP1M), quarterly (PP3M), and from 2020 also twice-yearly (PP6M). The latter was approved for the maintenance treatment of adults with schizophrenia and clinically stabilized with PP1M or PP3M.AREAS COVERED: Data from studies evaluating efficacy in the maintenance treatment of schizophrenia with PP6M are reviewed. Since no post-marketing safety stud...
Source: Expert Review of Neurotherapeutics - March 6, 2024 Category: Neurology Authors: Giovanna Cirnigliaro Vera Battini Michele Castiglioni Marica Renne Giulia Mosini Stefania Cheli Carla Carnovale Bernardo Dell'Osso Source Type: research