REM behavior disorder: When Parkinson's disease meets Morpheus
Rev Neurol (Paris). 2023 Aug 17:S0035-3787(23)00994-3. doi: 10.1016/j.neurol.2023.08.005. Online ahead of print.ABSTRACTRapid eye movement (REM) sleep behavior disorder (RBD) is a parasomnia characterized by the absence of normal muscle atonia during REM sleep, resulting in excessive motor activity while dreaming. RBD can be classified as isolated which is the strongest clinical marker of prodromal synucleinopathy, or secondary, associated with other neurological diseases, mainly Parkinson's disease (PD) and dementia with Lewy bodies. The diagnosis of RBD must be systematically documented by a video polysomnography in the ...
Source: Revue Neurologique - August 19, 2023 Category: Neurology Authors: P Dodet Source Type: research
Phenytoin-induced dyskinesia: a case report
ConclusionThis case presented a substantial reference value for the differential diagnosis and treatment prognosis of phenytoin-induced dyskinesia. The phenytoin-induced dyskinesia in this patient was successfully reversed with prompt identification and treatment. According to the case study ’s findings, such people may benefit from periodic therapeutic drug monitoring. (Source: Journal of Medical Case Reports)
Source: Journal of Medical Case Reports - July 21, 2023 Category: General Medicine Source Type: research
Involuntary Movements in Cobalamin Deficiency
Conclusion Recognition of nutritional cobalamin deficiency is important to
perform a differential diagnosis of the condition from seizures or other causes
of involuntary movements and avoid aggressive therapy and over treatment. [...] Georg Thieme Verlag Rüdigerstraße 14, 70469 Stuttgart,
GermanyArticle in Thieme eJournals: Table of contents | Abstract | Full text (Source: Klinische Padiatrie)
Source: Klinische Padiatrie - June 28, 2023 Category: Pediatrics Authors: Özyürek, Hamit Ince, Hulya Tasdemir, Haydar Ali Aydin, Omer Faruk Tags: Original Article Source Type: research
Liver enzyme inducing anticonvulsant drug use is associated with prevalent vertebral fracture
ConclusionLEI anticonvulsant use for ≥ 2 years is associated with higher vertebral fracture prevalence. Lateral spine VFA imaging at the time of bone densitometry may be appropriate for older individuals who have used LEI anticonvulsant medications for ≥ 2 years. (Source: Osteoporosis International)
Source: Osteoporosis International - June 28, 2023 Category: Orthopaedics Source Type: research
Retrospective cohort observation on psychotropic drug-drug interaction and identification utility from 3 databases: Drugs.com ®, Lexicomp®, and Epocrates®
ConclusionAmong three databases, interactions detected by Drugs.com ® were greatest in number, whereas Lexicomp® provided the broadest list of medications. Development of such databases, based on both theoretical and clinical conceptions, should be focused to balance safety of patients and weariness of healthcare providers. (Source: PLoS One)
Source: PLoS One - June 22, 2023 Category: Biomedical Science Authors: Ravi Pinkoh Source Type: research
Residual insomnia in major depressive disorder: a systematic review
ConclusionResidual insomnia is a very common complaint and most often appears as mid-nocturnal insomnia. Scarce data points out the benefits from pharmacotherapy, psychotherapy, and BA. More research is needed. (Source: Frontiers in Psychiatry)
Source: Frontiers in Psychiatry - June 16, 2023 Category: Psychiatry Source Type: research
Post-hypoxic myoclonus; what we know and gaps in knowledge
Trop Doct. 2023 Jun 7:494755231181153. doi: 10.1177/00494755231181153. Online ahead of print.ABSTRACTPost-hypoxic myoclonus (PHM) is a rare neurological complication having two different variants depending on acute or chronic onset after cardiopulmonary resuscitation following cardiac arrest: myoclonic status epilepticus (MSE) and Lance-Adams syndrome (LAS) respectively. Clinical and simultaneous electro-encephalographic (EEG) and electromyographic (EMG) tracing can distinguish between the two. Anecdotal treatment with benzodiazepines and anaesthetics (in the case of MSE) have been tried. Although limited evidence is avail...
Source: Tropical Doctor - June 8, 2023 Category: Tropical Medicine Authors: H Shafeeq Ahmed Source Type: research
Post-hypoxic myoclonus; what we know and gaps in knowledge
Trop Doct. 2023 Jun 7:494755231181153. doi: 10.1177/00494755231181153. Online ahead of print.ABSTRACTPost-hypoxic myoclonus (PHM) is a rare neurological complication having two different variants depending on acute or chronic onset after cardiopulmonary resuscitation following cardiac arrest: myoclonic status epilepticus (MSE) and Lance-Adams syndrome (LAS) respectively. Clinical and simultaneous electro-encephalographic (EEG) and electromyographic (EMG) tracing can distinguish between the two. Anecdotal treatment with benzodiazepines and anaesthetics (in the case of MSE) have been tried. Although limited evidence is avail...
Source: Tropical Doctor - June 8, 2023 Category: Tropical Medicine Authors: H Shafeeq Ahmed Source Type: research
