Clozapine-Induced Obsessive-Compulsive Symptoms and Augmentation with Clonazepam: Risks and Rationales
Turk Psikiyatri Derg. 2023 Spring;34(1):60-64. doi: 10.5080/u27025.ABSTRACTObsessive-compulsive symptoms induced by clozapine negatively affect treatment compliance. In some studies, clonazepam was shown to be beneficial in obsessive-compulsive disorder. However, in literature there are case reports of life-threatening complications associated with the combined use of clozapine and benzodiazepines. In this article, the efficacy and safety of the clonazepam augmentation were discussed in two patients who had obsessive-compulsive symptoms induced by clozapine. No life-threatening complications were detected during the follow...
Source: Turk Psikiyatri Dergisi - March 27, 2023 Category: Psychiatry Authors: Mehmet Ünler Sultan Efsun Tamdemir İrem Ekmekçi Ertek Zehra Arikan Source Type: research
Clozapine-Induced Obsessive-Compulsive Symptoms and Augmentation with Clonazepam: Risks and Rationales
Turk Psikiyatri Derg. 2023 Spring;34(1):60-64. doi: 10.5080/u27025.ABSTRACTObsessive-compulsive symptoms induced by clozapine negatively affect treatment compliance. In some studies, clonazepam was shown to be beneficial in obsessive-compulsive disorder. However, in literature there are case reports of life-threatening complications associated with the combined use of clozapine and benzodiazepines. In this article, the efficacy and safety of the clonazepam augmentation were discussed in two patients who had obsessive-compulsive symptoms induced by clozapine. No life-threatening complications were detected during the follow...
Source: Turkish Journal of Psychiatry - March 27, 2023 Category: Psychiatry Authors: Mehmet Ünler Sultan Efsun Tamdemir İrem Ekmekçi Ertek Zehra Arikan Source Type: research
Clozapine-Induced Obsessive-Compulsive Symptoms and Augmentation with Clonazepam: Risks and Rationales
Turk Psikiyatri Derg. 2023 Spring;34(1):60-64. doi: 10.5080/u27025.ABSTRACTObsessive-compulsive symptoms induced by clozapine negatively affect treatment compliance. In some studies, clonazepam was shown to be beneficial in obsessive-compulsive disorder. However, in literature there are case reports of life-threatening complications associated with the combined use of clozapine and benzodiazepines. In this article, the efficacy and safety of the clonazepam augmentation were discussed in two patients who had obsessive-compulsive symptoms induced by clozapine. No life-threatening complications were detected during the follow...
Source: Turk Psikiyatri Dergisi - March 27, 2023 Category: Psychiatry Authors: Mehmet Ünler Sultan Efsun Tamdemir İrem Ekmekçi Ertek Zehra Arikan Source Type: research
Clozapine-Induced Obsessive-Compulsive Symptoms and Augmentation with Clonazepam: Risks and Rationales
Turk Psikiyatri Derg. 2023 Spring;34(1):60-64. doi: 10.5080/u27025.ABSTRACTObsessive-compulsive symptoms induced by clozapine negatively affect treatment compliance. In some studies, clonazepam was shown to be beneficial in obsessive-compulsive disorder. However, in literature there are case reports of life-threatening complications associated with the combined use of clozapine and benzodiazepines. In this article, the efficacy and safety of the clonazepam augmentation were discussed in two patients who had obsessive-compulsive symptoms induced by clozapine. No life-threatening complications were detected during the follow...
Source: Turkish Journal of Psychiatry - March 27, 2023 Category: Psychiatry Authors: Mehmet Ünler Sultan Efsun Tamdemir İrem Ekmekçi Ertek Zehra Arikan Source Type: research
Clozapine-Induced Obsessive-Compulsive Symptoms and Augmentation with Clonazepam: Risks and Rationales
Turk Psikiyatri Derg. 2023 Spring;34(1):60-64. doi: 10.5080/u27025.ABSTRACTObsessive-compulsive symptoms induced by clozapine negatively affect treatment compliance. In some studies, clonazepam was shown to be beneficial in obsessive-compulsive disorder. However, in literature there are case reports of life-threatening complications associated with the combined use of clozapine and benzodiazepines. In this article, the efficacy and safety of the clonazepam augmentation were discussed in two patients who had obsessive-compulsive symptoms induced by clozapine. No life-threatening complications were detected during the follow...
Source: Turk Psikiyatri Dergisi - March 27, 2023 Category: Psychiatry Authors: Mehmet Ünler Sultan Efsun Tamdemir İrem Ekmekçi Ertek Zehra Arikan Source Type: research
Clozapine-Induced Obsessive-Compulsive Symptoms and Augmentation with Clonazepam: Risks and Rationales
Turk Psikiyatri Derg. 2023 Spring;34(1):60-64. doi: 10.5080/u27025.ABSTRACTObsessive-compulsive symptoms induced by clozapine negatively affect treatment compliance. In some studies, clonazepam was shown to be beneficial in obsessive-compulsive disorder. However, in literature there are case reports of life-threatening complications associated with the combined use of clozapine and benzodiazepines. In this article, the efficacy and safety of the clonazepam augmentation were discussed in two patients who had obsessive-compulsive symptoms induced by clozapine. No life-threatening complications were detected during the follow...
Source: Turkish Journal of Psychiatry - March 27, 2023 Category: Psychiatry Authors: Mehmet Ünler Sultan Efsun Tamdemir İrem Ekmekçi Ertek Zehra Arikan Source Type: research
Clozapine-Induced Obsessive-Compulsive Symptoms and Augmentation with Clonazepam: Risks and Rationales
Turk Psikiyatri Derg. 2023 Spring;34(1):60-64. doi: 10.5080/u27025.ABSTRACTObsessive-compulsive symptoms induced by clozapine negatively affect treatment compliance. In some studies, clonazepam was shown to be beneficial in obsessive-compulsive disorder. However, in literature there are case reports of life-threatening complications associated with the combined use of clozapine and benzodiazepines. In this article, the efficacy and safety of the clonazepam augmentation were discussed in two patients who had obsessive-compulsive symptoms induced by clozapine. No life-threatening complications were detected during the follow...
Source: Turk Psikiyatri Dergisi - March 27, 2023 Category: Psychiatry Authors: Mehmet Ünler Sultan Efsun Tamdemir İrem Ekmekçi Ertek Zehra Arikan Source Type: research
Clozapine-Induced Obsessive-Compulsive Symptoms and Augmentation with Clonazepam: Risks and Rationales
Turk Psikiyatri Derg. 2023 Spring;34(1):60-64. doi: 10.5080/u27025.ABSTRACTObsessive-compulsive symptoms induced by clozapine negatively affect treatment compliance. In some studies, clonazepam was shown to be beneficial in obsessive-compulsive disorder. However, in literature there are case reports of life-threatening complications associated with the combined use of clozapine and benzodiazepines. In this article, the efficacy and safety of the clonazepam augmentation were discussed in two patients who had obsessive-compulsive symptoms induced by clozapine. No life-threatening complications were detected during the follow...
Source: Turkish Journal of Psychiatry - March 27, 2023 Category: Psychiatry Authors: Mehmet Ünler Sultan Efsun Tamdemir İrem Ekmekçi Ertek Zehra Arikan Source Type: research
Clozapine-Induced Obsessive-Compulsive Symptoms and Augmentation with Clonazepam: Risks and Rationales
Turk Psikiyatri Derg. 2023 Spring;34(1):60-64. doi: 10.5080/u27025.ABSTRACTObsessive-compulsive symptoms induced by clozapine negatively affect treatment compliance. In some studies, clonazepam was shown to be beneficial in obsessive-compulsive disorder. However, in literature there are case reports of life-threatening complications associated with the combined use of clozapine and benzodiazepines. In this article, the efficacy and safety of the clonazepam augmentation were discussed in two patients who had obsessive-compulsive symptoms induced by clozapine. No life-threatening complications were detected during the follow...
Source: Turk Psikiyatri Dergisi - March 27, 2023 Category: Psychiatry Authors: Mehmet Ünler Sultan Efsun Tamdemir İrem Ekmekçi Ertek Zehra Arikan Source Type: research
Anti-seizure medication exposure and the risk of dementia: A meta-analysis of observational studies
ConclusionsThe statistically significant association between ASM and dementia in general population may be driven by unmeasured confounding or several individual first-generation ASMs. However, a higher risk of dementia was observed among bipolar disorder patients treated with ASMs. Given the few included studies and evidence of high heterogeneity, further larger, prospective studies that control for important confounders are needed to verify our findings. (Source: Frontiers in Neurology)
Source: Frontiers in Neurology - March 22, 2023 Category: Neurology Source Type: research
Benzodiazepine Analysis by an Improved LC-MS/MS Method Illustrates Usage Patterns in Washington State
CONCLUSION: New illicit benzodiazepines have emerged regionally and nationally. The inclusion of novel drugs in LC-MS/MS assay was helpful in properly characterizing the epidemiology of benzodiazepine use in our patient population. This information will lead to better assay result interpretations and patient care, and our experiences provide a roadmap for other clinical laboratories looking to expand their testing menu or transition to new instrumentation.PMID:36934953 | DOI:10.1016/j.cca.2023.117274 (Source: International Journal of Clinical Chemistry)
Source: International Journal of Clinical Chemistry - March 19, 2023 Category: Chemistry Authors: Ka Keung Chan Andrea J Moore Andrew N Hoofnagle Geoffrey S Baird Hsuan-Chieh Liao Source Type: research
Benzodiazepine Analysis by an Improved LC-MS/MS Method Illustrates Usage Patterns in Washington State
CONCLUSION: New illicit benzodiazepines have emerged regionally and nationally. The inclusion of novel drugs in LC-MS/MS assay was helpful in properly characterizing the epidemiology of benzodiazepine use in our patient population. This information will lead to better assay result interpretations and patient care, and our experiences provide a roadmap for other clinical laboratories looking to expand their testing menu or transition to new instrumentation.PMID:36934953 | DOI:10.1016/j.cca.2023.117274 (Source: International Journal of Clinical Chemistry)
Source: International Journal of Clinical Chemistry - March 19, 2023 Category: Chemistry Authors: Ka Keung Chan Andrea J Moore Andrew N Hoofnagle Geoffrey S Baird Hsuan-Chieh Liao Source Type: research
Sales trends of psychotropic drugs in the COVID-19 pandemic: A national database study in Brazil
Conclusions: The increase in sales, mainly of antidepressants during the COVID-19 pandemic, draws attention to issues related to the mental health of the Brazilian population and on the need for greater monitoring in the dispensing of these drugs. (Source: Frontiers in Pharmacology)
Source: Frontiers in Pharmacology - March 17, 2023 Category: Drugs & Pharmacology Source Type: research
Euterpe oleracea-based biochar for clonazepam adsorption: synthesis, characterization, adsorption properties, and toxicity assays
Environ Sci Pollut Res Int. 2023 Feb 25. doi: 10.1007/s11356-023-26044-y. Online ahead of print.ABSTRACTThe consumption of açaí fruit (Euterpe oleracea) has largely increased worldwide, resulting in a significant increase in the demand for its pulp. As a result, the small producing communities end up with large amounts of açaí endocarp residues, creating local environmental pollution problems. Therefore, chemical and physical routes were investigated for producing açaí endocarp adsorbents to propose a locally viable solution for this problem. The adsorption properties of the produced biochars were tested for clonazep...
Source: Environmental Science and Pollution Research International - February 25, 2023 Category: Environmental Health Authors: Ronald K S Santos Carlos Schnorr Luis F O Silva Bruna F Nascimento Jorge V F L Cavalcanti Yasmin Vieira Guilherme L Dotto Maur ício A Motta Sobrinho Source Type: research
