Anti-seizure medication exposure and the risk of dementia: A meta-analysis of observational studies

ConclusionsThe statistically significant association between ASM and dementia in general population may be driven by unmeasured confounding or several individual first-generation ASMs. However, a higher risk of dementia was observed among bipolar disorder patients treated with ASMs. Given the few included studies and evidence of high heterogeneity, further larger, prospective studies that control for important confounders are needed to verify our findings.
Source: Frontiers in Neurology - Category: Neurology Source Type: research