At a glance
Accurate detection and grading of pterygium through smartphone by a fusion training model (see page 336) The authors' fusion model method works as a helpful tool for improving pterygium detection and grading accuracy in the context of insufficient smartphone data in the absence of a mobile mature database. Collagen type XII is undetectable in keratoconus Bowman’s layer (see page 343) Collagen type XII, a regulator of corneal form and stability, is undetectable in Bowman’s layer of keratoconic corneas, suggesting a possible integral role in the pathogenesis of keratoconus. Differentiating stages of functional vi...
Source: British Journal of Ophthalmology - February 21, 2024 Category: Opthalmology Authors: Larkin, F. Tags: Highlights from this issue Source Type: research
Collagen type XII is undetectable in keratoconus Bowmans layer
Conclusions
The apparent absence of COL12A1 in KC BL, together with the functional importance that COL12A1 is thought to have in stress bearing areas, suggests that COL12A1 may play a role in the pathogenesis of KC. Further studies are necessary to investigate the mechanisms that lead to COL12A1 dysregulation in KC. (Source: British Journal of Ophthalmology)
Source: British Journal of Ophthalmology - February 21, 2024 Category: Opthalmology Authors: Rigi, M., Son, H.-S., Moon, L., Matthaei, M., Srikumaran, D., Jun, A. S., Eberhart, C. G., Soiberman, U. S. Tags: Cornea and ocular surface Source Type: research
A Cross-Sectional Analysis to Assess the Role of Atopy in Keratoconus Among Saudi Population [Corrigendum]
(Source: International Journal of General Medicine)
Source: International Journal of General Medicine - February 19, 2024 Category: General Medicine Tags: International Journal of General Medicine Source Type: research
A comparison of conventional and accelerated corneal crosslinking: corneal epithelial remodeling and in vivo confocal microscopy analysis
ConclusionBoth conventional and accelerated CXL treatments appear to be effective in halting the progression of KC. Corneal epithelial irregularity slightly improves after CXL. The regeneration of subbasal nerves is faster after A-CXL treatment. (Source: International Ophthalmology)
Source: International Ophthalmology - February 16, 2024 Category: Opthalmology Source Type: research
Revisiting rabbit models for keratoconus: A long-term study on collagenase-induced disease progression
This study evaluates the long-term stability of collagenase type II induced KC in a rabbit model. Six New Zealand rabbits were divided into 4 study groups with 3 eyes per group. The groups were control (group 1), 0.5% proparacaine + 5 min collagenase treatment on day 0 and day 30 (group 2), 0.5% proparacaine + 10 min collagenase treatment on day 0 (group 3) and, mechanical debridement + 2 mins collagenase treatment on day 0 (group 4). Inflammation was observed in group 4 till week 10. Significant decrease in the central corneal thickness was observed in group 3 by week 4 (p < 0.001) however, the thickness was regained i...
Source: Experimental Eye Research - February 13, 2024 Category: Opthalmology Authors: Sujithra Shankar Minal Thacker Abhishek Sahoo Aniruth Reddy Aindla Khyathi Ratna Padala Jilu Jaffet Kiran Kumar Bokara Sayan Basu Vivek Singh Source Type: research
Outcomes after corneal crosslinking treatment in paediatric patients with keratoconus
ConclusionThe findings suggest that accelerated corneal crosslinking treatment is effective in slowing or halting the progression of keratoconus. Furthermore, there were no persistent overt complications observed at 12 months after the procedure. (Source: International Ophthalmology)
Source: International Ophthalmology - February 12, 2024 Category: Opthalmology Source Type: research
Pediatric keratoconus epidemiology: a systematic scoping review
ConclusionsRecent epidemiological studies with better methodologies demonstrated increased prevalence rates in comparison to the older literature. This effect may be due to better diagnostic methods and better sample selection than those in historical studies. Diagnosis remains a major challenge as the early disease is usually asymptomatic. Economic and social aspects of pediatric KC remain understudied in the pediatric literature. Global, inclusive, and proactive screening studies in schools are imperative to better understand the great impact of this disease in the young. (Source: International Ophthalmology)
Source: International Ophthalmology - February 12, 2024 Category: Opthalmology Source Type: research
The Ayounkon project: visual impairment, eye diseases and unmet eye care needs in the Syrian refugee population and the hosting community in Lebanon
ConclusionThe Syrian refugee population and the Lebanese host community have a high prevalence of ophthalmic pathologies and SVI/BL. Visual impairment is more prevalent in the refugee population. Our findings underscore the importance of targeted interventions and access to eye care services for these populations. (Source: International Ophthalmology)
Source: International Ophthalmology - February 9, 2024 Category: Opthalmology Source Type: research
Intrastromal corneal ring segments for keratoconus patients: up to 12 years follow up
ConclusionThis study represents the largest follow up for ICRS implanted in keratoconus patients. Improvement of visual acuity following ICRS implantation can be expected in the first few years, after which, a decline occurring thereafter. (Source: International Ophthalmology)
Source: International Ophthalmology - February 9, 2024 Category: Opthalmology Source Type: research
Determination of the toric axis by using internal astigmatism axis in non-dilated eyes
ConclusionsIn eyes with toric IOL implantation, the IOL axis and IOL rotation according to target IOL axis can be detected easily and effectively in a short time by OPD scan internal astigmatism axis without the need to dilate the pupil. (Source: International Ophthalmology)
Source: International Ophthalmology - February 9, 2024 Category: Opthalmology Source Type: research
Corneal pseudoectasia: a case series
ConclusionsTomography patterns mimicking corneal ectasia can appear in patients without ectatic pathology. The comprehensive ophthalmologist should be aware of such cases as they may substantially alter the treatment course and prognosis of these patients. (Source: International Ophthalmology)
Source: International Ophthalmology - February 7, 2024 Category: Opthalmology Source Type: research
Response to Altamirano-Lamarque et al. Comment on “Prevalence and economic burden of Keratoconus in the United States”
Response: (Source: American Journal of Ophthalmology)
Source: American Journal of Ophthalmology - January 31, 2024 Category: Opthalmology Authors: Rohan Bir Singh, Uday Pratap Singh Parmar, Vishal Jhanji Tags: Correspondence Source Type: research
Comment on “Prevalence and economic burden of Keratoconus in the United States”
In this cross-sectional study,1 Bir Singh et al. used data from the Vision and Eye Health Surveillance System (VEHSS) to describe the prevalence of keratoconus in the US. The authors use this estimate to extrapolate on trends in the economic burden of keratoconus. The total lifetime cost of keratoconus in the US was found to increase by $1.2 billion ($2.6 to $3.8 billion) over a 4-year period (2016 to 2019) – a drastic increase over a short period of time. There are several important limitations to consider when interpreting the results of this study. (Source: American Journal of Ophthalmology)
Source: American Journal of Ophthalmology - January 31, 2024 Category: Opthalmology Authors: Francisco Altamirano-Lamarque, Isdin Oke Tags: Correspondence Source Type: research
Response to Comment on: Prevalence and Economic Burden of Keratoconus in the United States
We thank Drs. Altamirano-Lamarque and Oke for their feedback on our manuscript entitled “Prevalence and Economic Burden of Keratoconus in the United States.”1 We concur with some of the observations stated by the authors in the letter. (Source: American Journal of Ophthalmology)
Source: American Journal of Ophthalmology - January 31, 2024 Category: Opthalmology Authors: ROHAN BIR SINGH, UDAY PRATAP SINGH PARMAR, VISHAL JHANJI Tags: Correspondence Source Type: research
Distribution and causes of blindness and severe visual impairment in children at a tertiary referral centre in Rwanda
Conclusion
The high number of avoidable causes for SVI/BL may be reduced through several cost-effective ways. (Source: British Journal of Ophthalmology)
Source: British Journal of Ophthalmology - January 29, 2024 Category: Opthalmology Authors: El-Khoury, S., Strittmatter, S., Tuyisabe, T., Preussner, P.-R., Abdelmassih, Y. Tags: Paediatric ophthalmology Source Type: research
