Collagen type XII is undetectable in keratoconus Bowmans layer

Conclusions The apparent absence of COL12A1 in KC BL, together with the functional importance that COL12A1 is thought to have in stress bearing areas, suggests that COL12A1 may play a role in the pathogenesis of KC. Further studies are necessary to investigate the mechanisms that lead to COL12A1 dysregulation in KC.

http://bjo.bmj.com/cgi/content/short/108/3/343?rss=1

Source: British Journal of Ophthalmology - February 21, 2024 Category: Opthalmology Authors: Rigi, M., Son, H.-S., Moon, L., Matthaei, M., Srikumaran, D., Jun, A. S., Eberhart, C. G., Soiberman, U. S. Tags: Cornea and ocular surface Source Type: research