Genetic and Familial Influences on Self-Perception in Early Childhood and Self-Esteem in Adulthood: A Cross-Sectional Analysis
Twin Res Hum Genet. 2023 Oct 20:1-14. doi: 10.1017/thg.2023.44. Online ahead of print.ABSTRACTSelf-perception in early childhood and self-esteem in adulthood are related to a variety of aspects of psychological wellbeing. The goal of the present study was to examine genetic and familial influences on self-perception and self-esteem in separate samples of children (153 twin pairs of 5-year-olds) and adults (753 twin pairs between the ages of 25-75 years). Genetic common factor modeling showed that three facets of self-perception (physical competence, peer acceptance, and maternal acceptance) loaded onto a single heritable f...
Source: Twin Research and Human Genetics - October 20, 2023 Category: Genetics & Stem Cells Authors: Riley L Marshall Lisabeth Fisher DiLalla Colin R Harbke Emily C Pali Source Type: research
Genetic and Familial Influences on Self-Perception in Early Childhood and Self-Esteem in Adulthood: A Cross-Sectional Analysis
Twin Res Hum Genet. 2023 Oct 20:1-14. doi: 10.1017/thg.2023.44. Online ahead of print.ABSTRACTSelf-perception in early childhood and self-esteem in adulthood are related to a variety of aspects of psychological wellbeing. The goal of the present study was to examine genetic and familial influences on self-perception and self-esteem in separate samples of children (153 twin pairs of 5-year-olds) and adults (753 twin pairs between the ages of 25-75 years). Genetic common factor modeling showed that three facets of self-perception (physical competence, peer acceptance, and maternal acceptance) loaded onto a single heritable f...
Source: Twin Research and Human Genetics - October 20, 2023 Category: Genetics & Stem Cells Authors: Riley L Marshall Lisabeth Fisher DiLalla Colin R Harbke Emily C Pali Source Type: research
Genetic and Familial Influences on Self-Perception in Early Childhood and Self-Esteem in Adulthood: A Cross-Sectional Analysis
Twin Res Hum Genet. 2023 Oct 20:1-14. doi: 10.1017/thg.2023.44. Online ahead of print.ABSTRACTSelf-perception in early childhood and self-esteem in adulthood are related to a variety of aspects of psychological wellbeing. The goal of the present study was to examine genetic and familial influences on self-perception and self-esteem in separate samples of children (153 twin pairs of 5-year-olds) and adults (753 twin pairs between the ages of 25-75 years). Genetic common factor modeling showed that three facets of self-perception (physical competence, peer acceptance, and maternal acceptance) loaded onto a single heritable f...
Source: Twin Research and Human Genetics - October 20, 2023 Category: Genetics & Stem Cells Authors: Riley L Marshall Lisabeth Fisher DiLalla Colin R Harbke Emily C Pali Source Type: research
Genetic and Familial Influences on Self-Perception in Early Childhood and Self-Esteem in Adulthood: A Cross-Sectional Analysis
Twin Res Hum Genet. 2023 Oct 20:1-14. doi: 10.1017/thg.2023.44. Online ahead of print.ABSTRACTSelf-perception in early childhood and self-esteem in adulthood are related to a variety of aspects of psychological wellbeing. The goal of the present study was to examine genetic and familial influences on self-perception and self-esteem in separate samples of children (153 twin pairs of 5-year-olds) and adults (753 twin pairs between the ages of 25-75 years). Genetic common factor modeling showed that three facets of self-perception (physical competence, peer acceptance, and maternal acceptance) loaded onto a single heritable f...
Source: Twin Research and Human Genetics - October 20, 2023 Category: Genetics & Stem Cells Authors: Riley L Marshall Lisabeth Fisher DiLalla Colin R Harbke Emily C Pali Source Type: research
Genetic and Familial Influences on Self-Perception in Early Childhood and Self-Esteem in Adulthood: A Cross-Sectional Analysis
Twin Res Hum Genet. 2023 Oct 20:1-14. doi: 10.1017/thg.2023.44. Online ahead of print.ABSTRACTSelf-perception in early childhood and self-esteem in adulthood are related to a variety of aspects of psychological wellbeing. The goal of the present study was to examine genetic and familial influences on self-perception and self-esteem in separate samples of children (153 twin pairs of 5-year-olds) and adults (753 twin pairs between the ages of 25-75 years). Genetic common factor modeling showed that three facets of self-perception (physical competence, peer acceptance, and maternal acceptance) loaded onto a single heritable f...
Source: Twin Research and Human Genetics - October 20, 2023 Category: Genetics & Stem Cells Authors: Riley L Marshall Lisabeth Fisher DiLalla Colin R Harbke Emily C Pali Source Type: research
Genetic and Familial Influences on Self-Perception in Early Childhood and Self-Esteem in Adulthood: A Cross-Sectional Analysis
Twin Res Hum Genet. 2023 Oct 20:1-14. doi: 10.1017/thg.2023.44. Online ahead of print.ABSTRACTSelf-perception in early childhood and self-esteem in adulthood are related to a variety of aspects of psychological wellbeing. The goal of the present study was to examine genetic and familial influences on self-perception and self-esteem in separate samples of children (153 twin pairs of 5-year-olds) and adults (753 twin pairs between the ages of 25-75 years). Genetic common factor modeling showed that three facets of self-perception (physical competence, peer acceptance, and maternal acceptance) loaded onto a single heritable f...
Source: Twin Research and Human Genetics - October 20, 2023 Category: Genetics & Stem Cells Authors: Riley L Marshall Lisabeth Fisher DiLalla Colin R Harbke Emily C Pali Source Type: research
Genetic and Familial Influences on Self-Perception in Early Childhood and Self-Esteem in Adulthood: A Cross-Sectional Analysis
Twin Res Hum Genet. 2023 Oct 20:1-14. doi: 10.1017/thg.2023.44. Online ahead of print.ABSTRACTSelf-perception in early childhood and self-esteem in adulthood are related to a variety of aspects of psychological wellbeing. The goal of the present study was to examine genetic and familial influences on self-perception and self-esteem in separate samples of children (153 twin pairs of 5-year-olds) and adults (753 twin pairs between the ages of 25-75 years). Genetic common factor modeling showed that three facets of self-perception (physical competence, peer acceptance, and maternal acceptance) loaded onto a single heritable f...
Source: Twin Research and Human Genetics - October 20, 2023 Category: Genetics & Stem Cells Authors: Riley L Marshall Lisabeth Fisher DiLalla Colin R Harbke Emily C Pali Source Type: research
Genetic and Familial Influences on Self-Perception in Early Childhood and Self-Esteem in Adulthood: A Cross-Sectional Analysis
Twin Res Hum Genet. 2023 Oct 20:1-14. doi: 10.1017/thg.2023.44. Online ahead of print.ABSTRACTSelf-perception in early childhood and self-esteem in adulthood are related to a variety of aspects of psychological wellbeing. The goal of the present study was to examine genetic and familial influences on self-perception and self-esteem in separate samples of children (153 twin pairs of 5-year-olds) and adults (753 twin pairs between the ages of 25-75 years). Genetic common factor modeling showed that three facets of self-perception (physical competence, peer acceptance, and maternal acceptance) loaded onto a single heritable f...
Source: Twin Research and Human Genetics - October 20, 2023 Category: Genetics & Stem Cells Authors: Riley L Marshall Lisabeth Fisher DiLalla Colin R Harbke Emily C Pali Source Type: research
Cap Analysis of Gene Expression Clarifies Transcriptomic Divergence Within Monozygotic Twin Pairs
In this study, we performed cap analysis of gene expression on three pairs of twins and clustered each individual based on their expression profiles of annotated genes. The dendrogram of annotated gene transcripts showed a monophyletic clade for each twin pair. We also analyzed the expression of retrotransposons, such as human endogenous retroviruses (HERVs) and long interspersed nuclear elements (LINEs), given their abundance in the genome. Clustering analyses demonstrated that HERV and LINE expression diverged even within monozygotic twin pairs. Thus, HERVs and LINEs are more susceptible to nonshared factors than annotat...
Source: Twin Research and Human Genetics - October 17, 2023 Category: Genetics & Stem Cells Authors: Hirokazu Katoh Hiroaki Asai Keiko Takemoto Rie Tomizawa Chika Honda Mikio Watanabe Osaka Twin Research Group Tomoyuki Honda Source Type: research
Cap Analysis of Gene Expression Clarifies Transcriptomic Divergence Within Monozygotic Twin Pairs
In this study, we performed cap analysis of gene expression on three pairs of twins and clustered each individual based on their expression profiles of annotated genes. The dendrogram of annotated gene transcripts showed a monophyletic clade for each twin pair. We also analyzed the expression of retrotransposons, such as human endogenous retroviruses (HERVs) and long interspersed nuclear elements (LINEs), given their abundance in the genome. Clustering analyses demonstrated that HERV and LINE expression diverged even within monozygotic twin pairs. Thus, HERVs and LINEs are more susceptible to nonshared factors than annotat...
Source: Twin Research and Human Genetics - October 17, 2023 Category: Genetics & Stem Cells Authors: Hirokazu Katoh Hiroaki Asai Keiko Takemoto Rie Tomizawa Chika Honda Mikio Watanabe Osaka Twin Research Group Tomoyuki Honda Source Type: research
Estimating the Genetic Contribution to Astigmatism and Myopia in the Mexican Population
This study aimed to estimate the genetic contribution to astigmatism and myopia in the Mexican population. A sample of 1399 families, including 243 twin pairs and 1156 single twins, completed a medical questionnaire about their own and their co-twin's diagnosis of astigmatism and myopia. Concordance rates for astigmatism and myopia were estimated, and heritability and genetic correlations were determined using a bivariate ACE Cholesky decomposition method, decomposed into A (additive genetic), C (shared environmental) and E (unique environmental) components. The results showed a higher concordance rate for astigmatism and ...
Source: Twin Research and Human Genetics - October 16, 2023 Category: Genetics & Stem Cells Authors: Tal ía V Román-López Brisa Garc ía-Vilchis Vanessa Murillo-Lechuga Enrique Chiu-Han Xanat L ópez-Camaño Oscar Aldana-Assad Santiago Diaz-Torres Ulises Caballero-S ánchez Ivett Ortega-Mora Diego Ram írez-González Diego Zenteno Zaida Espinosa-Vald Source Type: research
Effects of Genetic Relatedness of Kin Pairs on Univariate ACE Model Performance
Twin Res Hum Genet. 2023 Oct 6:1-12. doi: 10.1017/thg.2023.40. Online ahead of print.ABSTRACTThe current study explored the impact of genetic relatedness differences (ΔH) and sample size on the performance of nonclassical ACE models, with a focus on same-sex and opposite-sex twin groups. The ACE model is a statistical model that posits that additive genetic factors (A), common environmental factors (C), and specific (or nonshared) environmental factors plus measurement error (E) account for individual differences in a phenotype. By extending Visscher's (2004) least squares paradigm and conducting simulations, we illustrat...
Source: Twin Research and Human Genetics - October 6, 2023 Category: Genetics & Stem Cells Authors: Xuanyu Lyu S Mason Garrison Source Type: research
Effects of Genetic Relatedness of Kin Pairs on Univariate ACE Model Performance
Twin Res Hum Genet. 2023 Oct 6:1-12. doi: 10.1017/thg.2023.40. Online ahead of print.ABSTRACTThe current study explored the impact of genetic relatedness differences (ΔH) and sample size on the performance of nonclassical ACE models, with a focus on same-sex and opposite-sex twin groups. The ACE model is a statistical model that posits that additive genetic factors (A), common environmental factors (C), and specific (or nonshared) environmental factors plus measurement error (E) account for individual differences in a phenotype. By extending Visscher's (2004) least squares paradigm and conducting simulations, we illustrat...
Source: Twin Research and Human Genetics - October 6, 2023 Category: Genetics & Stem Cells Authors: Xuanyu Lyu S Mason Garrison Source Type: research
Effects of Genetic Relatedness of Kin Pairs on Univariate ACE Model Performance
Twin Res Hum Genet. 2023 Oct 6:1-12. doi: 10.1017/thg.2023.40. Online ahead of print.ABSTRACTThe current study explored the impact of genetic relatedness differences (ΔH) and sample size on the performance of nonclassical ACE models, with a focus on same-sex and opposite-sex twin groups. The ACE model is a statistical model that posits that additive genetic factors (A), common environmental factors (C), and specific (or nonshared) environmental factors plus measurement error (E) account for individual differences in a phenotype. By extending Visscher's (2004) least squares paradigm and conducting simulations, we illustrat...
Source: Twin Research and Human Genetics - October 6, 2023 Category: Genetics & Stem Cells Authors: Xuanyu Lyu S Mason Garrison Source Type: research
Effects of Genetic Relatedness of Kin Pairs on Univariate ACE Model Performance
Twin Res Hum Genet. 2023 Oct 6:1-12. doi: 10.1017/thg.2023.40. Online ahead of print.ABSTRACTThe current study explored the impact of genetic relatedness differences (ΔH) and sample size on the performance of nonclassical ACE models, with a focus on same-sex and opposite-sex twin groups. The ACE model is a statistical model that posits that additive genetic factors (A), common environmental factors (C), and specific (or nonshared) environmental factors plus measurement error (E) account for individual differences in a phenotype. By extending Visscher's (2004) least squares paradigm and conducting simulations, we illustrat...
Source: Twin Research and Human Genetics - October 6, 2023 Category: Genetics & Stem Cells Authors: Xuanyu Lyu S Mason Garrison Source Type: research
