Partnership with the University of S ão Paulo Panel of Twins: A Four-City Tour and More / Twin Research Reviews: Twin Research on Binge Eating; Twins' Physical Outcomes Linked to Different Diets; Working Conditions and Sickness Absence in Swedish Twins; Facial Morphology Differences in Monozygotic Twins / Human Interest and Importance : Michigan Family Forced to Adopt Their Own Twins; Ethics of Hiring a Surrogate to Bear Twins; Twin Survivors of the Israel-Hamas War; Twin Pregnancy with Double Uterus; Three Twin Pairs on Same Women's Soccer Team
This article begins with an overview of twin research in Brazil, initiated by the University of São Paulo Panel of Twins. I met with many new research collaborators and students while on a fall 2023 four-city lecture tour in that country. A meeting with a world-famous surgeon who recently separated craniopagus conjoined twin pairs is also described. This overview is followed by summaries of twin research on binge eating, twins' physical outcomes linked to different diets, working conditions and sickness absence in Swedish Twins and facial morphology differences in monozygotic twins. The final section of this article provi...
Source: Twin Research and Human Genetics - February 21, 2024 Category: Genetics & Stem Cells Authors: Nancy L Segal Source Type: research

Partnership with the University of S ão Paulo Panel of Twins: A Four-City Tour and More / Twin Research Reviews: Twin Research on Binge Eating; Twins' Physical Outcomes Linked to Different Diets; Working Conditions and Sickness Absence in Swedish Twins; Facial Morphology Differences in Monozygotic Twins / Human Interest and Importance : Michigan Family Forced to Adopt Their Own Twins; Ethics of Hiring a Surrogate to Bear Twins; Twin Survivors of the Israel-Hamas War; Twin Pregnancy with Double Uterus; Three Twin Pairs on Same Women's Soccer Team
This article begins with an overview of twin research in Brazil, initiated by the University of São Paulo Panel of Twins. I met with many new research collaborators and students while on a fall 2023 four-city lecture tour in that country. A meeting with a world-famous surgeon who recently separated craniopagus conjoined twin pairs is also described. This overview is followed by summaries of twin research on binge eating, twins' physical outcomes linked to different diets, working conditions and sickness absence in Swedish Twins and facial morphology differences in monozygotic twins. The final section of this article provi...
Source: Twin Research and Human Genetics - February 21, 2024 Category: Genetics & Stem Cells Authors: Nancy L Segal Source Type: research

Partnership with the University of S ão Paulo Panel of Twins: A Four-City Tour and More / Twin Research Reviews: Twin Research on Binge Eating; Twins' Physical Outcomes Linked to Different Diets; Working Conditions and Sickness Absence in Swedish Twins; Facial Morphology Differences in Monozygotic Twins / Human Interest and Importance : Michigan Family Forced to Adopt Their Own Twins; Ethics of Hiring a Surrogate to Bear Twins; Twin Survivors of the Israel-Hamas War; Twin Pregnancy with Double Uterus; Three Twin Pairs on Same Women's Soccer Team
This article begins with an overview of twin research in Brazil, initiated by the University of São Paulo Panel of Twins. I met with many new research collaborators and students while on a fall 2023 four-city lecture tour in that country. A meeting with a world-famous surgeon who recently separated craniopagus conjoined twin pairs is also described. This overview is followed by summaries of twin research on binge eating, twins' physical outcomes linked to different diets, working conditions and sickness absence in Swedish Twins and facial morphology differences in monozygotic twins. The final section of this article provi...
Source: Twin Research and Human Genetics - February 21, 2024 Category: Genetics & Stem Cells Authors: Nancy L Segal Source Type: research

Partnership with the University of S ão Paulo Panel of Twins: A Four-City Tour and More / Twin Research Reviews: Twin Research on Binge Eating; Twins' Physical Outcomes Linked to Different Diets; Working Conditions and Sickness Absence in Swedish Twins; Facial Morphology Differences in Monozygotic Twins / Human Interest and Importance : Michigan Family Forced to Adopt Their Own Twins; Ethics of Hiring a Surrogate to Bear Twins; Twin Survivors of the Israel-Hamas War; Twin Pregnancy with Double Uterus; Three Twin Pairs on Same Women's Soccer Team
This article begins with an overview of twin research in Brazil, initiated by the University of São Paulo Panel of Twins. I met with many new research collaborators and students while on a fall 2023 four-city lecture tour in that country. A meeting with a world-famous surgeon who recently separated craniopagus conjoined twin pairs is also described. This overview is followed by summaries of twin research on binge eating, twins' physical outcomes linked to different diets, working conditions and sickness absence in Swedish Twins and facial morphology differences in monozygotic twins. The final section of this article provi...
Source: Twin Research and Human Genetics - February 21, 2024 Category: Genetics & Stem Cells Authors: Nancy L Segal Source Type: research

Trends in Twin Births and Survival in Bangladesh: An Analysis of Half a Century of Evidence
This study assessed the trends in twin births and their survival in Bangladesh by analyzing over a quarter million live births during 1970-2018, pooled from all eight rounds of the Bangladesh Demographic and Health Survey. In these five decades, the twinning rate increased by 1.5 times, from 5.8 to 8.6 twins per 1000 maternities. The decadal twinning rates varied across maternal age, parity, body mass index, household wealth index, and geographic region. The gap in decadal neonatal, infant, and under-five cumulative survival probability between singleton and multiple births was found to be closing, using Kaplan-Meier curve...
Source: Twin Research and Human Genetics - February 12, 2024 Category: Genetics & Stem Cells Authors: Kazi Zubair Hossain Iftekhar Hasan Source Type: research

Trends in Twin Births and Survival in Bangladesh: An Analysis of Half a Century of Evidence
This study assessed the trends in twin births and their survival in Bangladesh by analyzing over a quarter million live births during 1970-2018, pooled from all eight rounds of the Bangladesh Demographic and Health Survey. In these five decades, the twinning rate increased by 1.5 times, from 5.8 to 8.6 twins per 1000 maternities. The decadal twinning rates varied across maternal age, parity, body mass index, household wealth index, and geographic region. The gap in decadal neonatal, infant, and under-five cumulative survival probability between singleton and multiple births was found to be closing, using Kaplan-Meier curve...
Source: Twin Research and Human Genetics - February 12, 2024 Category: Genetics & Stem Cells Authors: Kazi Zubair Hossain Iftekhar Hasan Source Type: research

Trends in Twin Births and Survival in Bangladesh: An Analysis of Half a Century of Evidence
This study assessed the trends in twin births and their survival in Bangladesh by analyzing over a quarter million live births during 1970-2018, pooled from all eight rounds of the Bangladesh Demographic and Health Survey. In these five decades, the twinning rate increased by 1.5 times, from 5.8 to 8.6 twins per 1000 maternities. The decadal twinning rates varied across maternal age, parity, body mass index, household wealth index, and geographic region. The gap in decadal neonatal, infant, and under-five cumulative survival probability between singleton and multiple births was found to be closing, using Kaplan-Meier curve...
Source: Twin Research and Human Genetics - February 12, 2024 Category: Genetics & Stem Cells Authors: Kazi Zubair Hossain Iftekhar Hasan Source Type: research

Trends in Twin Births and Survival in Bangladesh: An Analysis of Half a Century of Evidence
This study assessed the trends in twin births and their survival in Bangladesh by analyzing over a quarter million live births during 1970-2018, pooled from all eight rounds of the Bangladesh Demographic and Health Survey. In these five decades, the twinning rate increased by 1.5 times, from 5.8 to 8.6 twins per 1000 maternities. The decadal twinning rates varied across maternal age, parity, body mass index, household wealth index, and geographic region. The gap in decadal neonatal, infant, and under-five cumulative survival probability between singleton and multiple births was found to be closing, using Kaplan-Meier curve...
Source: Twin Research and Human Genetics - February 12, 2024 Category: Genetics & Stem Cells Authors: Kazi Zubair Hossain Iftekhar Hasan Source Type: research

Trends in Twin Births and Survival in Bangladesh: An Analysis of Half a Century of Evidence
This study assessed the trends in twin births and their survival in Bangladesh by analyzing over a quarter million live births during 1970-2018, pooled from all eight rounds of the Bangladesh Demographic and Health Survey. In these five decades, the twinning rate increased by 1.5 times, from 5.8 to 8.6 twins per 1000 maternities. The decadal twinning rates varied across maternal age, parity, body mass index, household wealth index, and geographic region. The gap in decadal neonatal, infant, and under-five cumulative survival probability between singleton and multiple births was found to be closing, using Kaplan-Meier curve...
Source: Twin Research and Human Genetics - February 12, 2024 Category: Genetics & Stem Cells Authors: Kazi Zubair Hossain Iftekhar Hasan Source Type: research

DNA Methylation Mediated the Association of Body Mass Index With Blood Pressure in Chinese Monozygotic Twins
In conclusion, DNAm variation may partially negatively mediate the association of BMI with BP. Our findings may provide new clues to further elucidate the pathogenesis of obesity to hypertension and identify new diagnostic biomarkers and therapeutic targets for hypertension.PMID:38291711 | DOI:10.1017/thg.2024.3 (Source: Twin Research and Human Genetics)
Source: Twin Research and Human Genetics - January 31, 2024 Category: Genetics & Stem Cells Authors: Jie Yao Feng Ning Weijing Wang Dongfeng Zhang Source Type: research

Family History of Twinning and Fertility Traits in Nigerian Mothers of Dizygotic Twins
Twin Res Hum Genet. 2024 Jan 31:1-6. doi: 10.1017/thg.2024.2. Online ahead of print.ABSTRACTFamilial twinning and fertility traits were investigated in Nigerian mothers of dizygotic (DZ) twins (MoDZT; N = 972) and controls (N = 525) who responded to our person-to-person interview, which included questions on pregnancy history and family history of DZ twinning. Controls were defined as women who are not twins themselves and do not have twins in their first-degree relatives. Over 95% of the participants were Yoruba. We found that Nigerian MoDZT had an average of 4.0 (±2.6) pairs of twins among their relatives, and of these,...
Source: Twin Research and Human Genetics - January 31, 2024 Category: Genetics & Stem Cells Authors: Yoon-Mi Hur Nick Martin Olakunle Oginni Dorret Boomsma Nikki Hubers Hamdi Mbarek Source Type: research

National Trends in Suicides and Male Twin Live Births in the US, 2003 to 2019: An Updated Test of Collective Optimism and Selection in Utero
Twin Res Hum Genet. 2023 Dec 15:1-8. doi: 10.1017/thg.2023.49. Online ahead of print.ABSTRACTPrior research based on Swedish data suggests that collective optimism, as measured by monthly incidence of suicides, correlates inversely with selection in utero against male twins in a population. We test this finding in the US, which reports the highest suicide rate of all high-income countries, and examine whether monthly changes in overall suicides precede changes in the ratio of male twin to male singleton live births. Consistent with prior work, we also examine as a key independent variable, suicides among women aged 15-49 y...
Source: Twin Research and Human Genetics - December 15, 2023 Category: Genetics & Stem Cells Authors: Parvati Singh Samantha Gailey Abhery Das Tim A Bruckner Source Type: research

Comprehensive Multiomics Analysis of Monozygotic Twin Discordant for Double Outlet Right Ventricle
This study demonstrates a multiomics profile of discordant twins and explores the possible mechanism of DORV development. Global hypomethylation might be associated with the risk of CHDs. Specific genes and specific pathways, particularly those involving ECM-receptor interaction, focal adhesion and TGF-β signaling, might be involved in the occurrence of CHDs.PMID:38099413 | DOI:10.1017/thg.2023.51 (Source: Twin Research and Human Genetics)
Source: Twin Research and Human Genetics - December 15, 2023 Category: Genetics & Stem Cells Authors: Zhen Liu Nana Li Xiaoyu Pan Jun Li Shengli Li Qintong Li Ping Li Ying Deng Fang Chen Hui Jiang Wei Wang Dezhi Mu Ping Yu Jun Zhu Source Type: research

Association Between Dysmenorrhea and Risk of Epilepsy in East Asian Populations: A Bidirectional Two-Sample Mendelian Randomization Study
This study investigated the causal relevance of dysmenorrhea on epilepsy using Mendelian randomization (MR). We extracted instrumental variants for dysmenorrhea and epilepsy from published genomewide association study data, focusing on individuals of East Asian descent. A comprehensive suite of MR estimations and sensitivity analyses was performed to ensure the robustness of the findings. Each outcome database was analyzed separately in both directions. For dysmenorrhea and epilepsy, 7 and 3 genetic variants respectively were selectively extracted as instrumental variants. The results suggest that dysmenorrhea is causally ...
Source: Twin Research and Human Genetics - December 15, 2023 Category: Genetics & Stem Cells Authors: Yuehan Ren Junning Zhang Tong Chen Jiaqin Chen Yan Liao Tingxiu Liu Liangliang Yang Chang Liu Xinmin Liu Baoqin Liu Source Type: research

National Trends in Suicides and Male Twin Live Births in the US, 2003 to 2019: An Updated Test of Collective Optimism and Selection in Utero
Twin Res Hum Genet. 2023 Dec 15:1-8. doi: 10.1017/thg.2023.49. Online ahead of print.ABSTRACTPrior research based on Swedish data suggests that collective optimism, as measured by monthly incidence of suicides, correlates inversely with selection in utero against male twins in a population. We test this finding in the US, which reports the highest suicide rate of all high-income countries, and examine whether monthly changes in overall suicides precede changes in the ratio of male twin to male singleton live births. Consistent with prior work, we also examine as a key independent variable, suicides among women aged 15-49 y...
Source: Twin Research and Human Genetics - December 15, 2023 Category: Genetics & Stem Cells Authors: Parvati Singh Samantha Gailey Abhery Das Tim A Bruckner Source Type: research