Candidate Genes for Prediction of Efficacy and Safety of Statin Therapy in the Kazakh Population
Twin Res Hum Genet. 2023 Jul 25:1-7. doi: 10.1017/thg.2023.28. Online ahead of print.ABSTRACTThe purpose of this research was to determine the frequency of mutation of the cytochrome CYP3A5 genes and transport proteins SLCO1B1 and MDR1 in patients with coronary heart disease in the Kazakh nation. A prospective cohort clinical and genetic study was conducted. The study was conducted in 2017-2019. Medical records containing information about drug prescription conducted in hospitals and outpatient departments were carefully analyzed. In the examined group of 178 patients treated with statins, a significant frequency of geneti...
Source: Twin Research and Human Genetics - July 25, 2023 Category: Genetics & Stem Cells Authors: Raikhan Y Tuleutayeva Assem R Makhatova Saule O Rakhyzhanova Lashyn K Zhazykbayeva Dana K Kozhakhmetova Source Type: research

Candidate Genes for Prediction of Efficacy and Safety of Statin Therapy in the Kazakh Population
Twin Res Hum Genet. 2023 Jul 25:1-7. doi: 10.1017/thg.2023.28. Online ahead of print.ABSTRACTThe purpose of this research was to determine the frequency of mutation of the cytochrome CYP3A5 genes and transport proteins SLCO1B1 and MDR1 in patients with coronary heart disease in the Kazakh nation. A prospective cohort clinical and genetic study was conducted. The study was conducted in 2017-2019. Medical records containing information about drug prescription conducted in hospitals and outpatient departments were carefully analyzed. In the examined group of 178 patients treated with statins, a significant frequency of geneti...
Source: Twin Research and Human Genetics - July 25, 2023 Category: Genetics & Stem Cells Authors: Raikhan Y Tuleutayeva Assem R Makhatova Saule O Rakhyzhanova Lashyn K Zhazykbayeva Dana K Kozhakhmetova Source Type: research

Candidate Genes for Prediction of Efficacy and Safety of Statin Therapy in the Kazakh Population
Twin Res Hum Genet. 2023 Jul 25:1-7. doi: 10.1017/thg.2023.28. Online ahead of print.ABSTRACTThe purpose of this research was to determine the frequency of mutation of the cytochrome CYP3A5 genes and transport proteins SLCO1B1 and MDR1 in patients with coronary heart disease in the Kazakh nation. A prospective cohort clinical and genetic study was conducted. The study was conducted in 2017-2019. Medical records containing information about drug prescription conducted in hospitals and outpatient departments were carefully analyzed. In the examined group of 178 patients treated with statins, a significant frequency of geneti...
Source: Twin Research and Human Genetics - July 25, 2023 Category: Genetics & Stem Cells Authors: Raikhan Y Tuleutayeva Assem R Makhatova Saule O Rakhyzhanova Lashyn K Zhazykbayeva Dana K Kozhakhmetova Source Type: research

Candidate Genes for Prediction of Efficacy and Safety of Statin Therapy in the Kazakh Population
Twin Res Hum Genet. 2023 Jul 25:1-7. doi: 10.1017/thg.2023.28. Online ahead of print.ABSTRACTThe purpose of this research was to determine the frequency of mutation of the cytochrome CYP3A5 genes and transport proteins SLCO1B1 and MDR1 in patients with coronary heart disease in the Kazakh nation. A prospective cohort clinical and genetic study was conducted. The study was conducted in 2017-2019. Medical records containing information about drug prescription conducted in hospitals and outpatient departments were carefully analyzed. In the examined group of 178 patients treated with statins, a significant frequency of geneti...
Source: Twin Research and Human Genetics - July 25, 2023 Category: Genetics & Stem Cells Authors: Raikhan Y Tuleutayeva Assem R Makhatova Saule O Rakhyzhanova Lashyn K Zhazykbayeva Dana K Kozhakhmetova Source Type: research

Candidate Genes for Prediction of Efficacy and Safety of Statin Therapy in the Kazakh Population
Twin Res Hum Genet. 2023 Jul 25:1-7. doi: 10.1017/thg.2023.28. Online ahead of print.ABSTRACTThe purpose of this research was to determine the frequency of mutation of the cytochrome CYP3A5 genes and transport proteins SLCO1B1 and MDR1 in patients with coronary heart disease in the Kazakh nation. A prospective cohort clinical and genetic study was conducted. The study was conducted in 2017-2019. Medical records containing information about drug prescription conducted in hospitals and outpatient departments were carefully analyzed. In the examined group of 178 patients treated with statins, a significant frequency of geneti...
Source: Twin Research and Human Genetics - July 25, 2023 Category: Genetics & Stem Cells Authors: Raikhan Y Tuleutayeva Assem R Makhatova Saule O Rakhyzhanova Lashyn K Zhazykbayeva Dana K Kozhakhmetova Source Type: research

Candidate Genes for Prediction of Efficacy and Safety of Statin Therapy in the Kazakh Population
Twin Res Hum Genet. 2023 Jul 25:1-7. doi: 10.1017/thg.2023.28. Online ahead of print.ABSTRACTThe purpose of this research was to determine the frequency of mutation of the cytochrome CYP3A5 genes and transport proteins SLCO1B1 and MDR1 in patients with coronary heart disease in the Kazakh nation. A prospective cohort clinical and genetic study was conducted. The study was conducted in 2017-2019. Medical records containing information about drug prescription conducted in hospitals and outpatient departments were carefully analyzed. In the examined group of 178 patients treated with statins, a significant frequency of geneti...
Source: Twin Research and Human Genetics - July 25, 2023 Category: Genetics & Stem Cells Authors: Raikhan Y Tuleutayeva Assem R Makhatova Saule O Rakhyzhanova Lashyn K Zhazykbayeva Dana K Kozhakhmetova Source Type: research

Candidate Genes for Prediction of Efficacy and Safety of Statin Therapy in the Kazakh Population
Twin Res Hum Genet. 2023 Jul 25:1-7. doi: 10.1017/thg.2023.28. Online ahead of print.ABSTRACTThe purpose of this research was to determine the frequency of mutation of the cytochrome CYP3A5 genes and transport proteins SLCO1B1 and MDR1 in patients with coronary heart disease in the Kazakh nation. A prospective cohort clinical and genetic study was conducted. The study was conducted in 2017-2019. Medical records containing information about drug prescription conducted in hospitals and outpatient departments were carefully analyzed. In the examined group of 178 patients treated with statins, a significant frequency of geneti...
Source: Twin Research and Human Genetics - July 25, 2023 Category: Genetics & Stem Cells Authors: Raikhan Y Tuleutayeva Assem R Makhatova Saule O Rakhyzhanova Lashyn K Zhazykbayeva Dana K Kozhakhmetova Source Type: research

Candidate Genes for Prediction of Efficacy and Safety of Statin Therapy in the Kazakh Population
Twin Res Hum Genet. 2023 Jul 25:1-7. doi: 10.1017/thg.2023.28. Online ahead of print.ABSTRACTThe purpose of this research was to determine the frequency of mutation of the cytochrome CYP3A5 genes and transport proteins SLCO1B1 and MDR1 in patients with coronary heart disease in the Kazakh nation. A prospective cohort clinical and genetic study was conducted. The study was conducted in 2017-2019. Medical records containing information about drug prescription conducted in hospitals and outpatient departments were carefully analyzed. In the examined group of 178 patients treated with statins, a significant frequency of geneti...
Source: Twin Research and Human Genetics - July 25, 2023 Category: Genetics & Stem Cells Authors: Raikhan Y Tuleutayeva Assem R Makhatova Saule O Rakhyzhanova Lashyn K Zhazykbayeva Dana K Kozhakhmetova Source Type: research

Candidate Genes for Prediction of Efficacy and Safety of Statin Therapy in the Kazakh Population
Twin Res Hum Genet. 2023 Jul 25:1-7. doi: 10.1017/thg.2023.28. Online ahead of print.ABSTRACTThe purpose of this research was to determine the frequency of mutation of the cytochrome CYP3A5 genes and transport proteins SLCO1B1 and MDR1 in patients with coronary heart disease in the Kazakh nation. A prospective cohort clinical and genetic study was conducted. The study was conducted in 2017-2019. Medical records containing information about drug prescription conducted in hospitals and outpatient departments were carefully analyzed. In the examined group of 178 patients treated with statins, a significant frequency of geneti...
Source: Twin Research and Human Genetics - July 25, 2023 Category: Genetics & Stem Cells Authors: Raikhan Y Tuleutayeva Assem R Makhatova Saule O Rakhyzhanova Lashyn K Zhazykbayeva Dana K Kozhakhmetova Source Type: research

Candidate Genes for Prediction of Efficacy and Safety of Statin Therapy in the Kazakh Population
Twin Res Hum Genet. 2023 Jul 25:1-7. doi: 10.1017/thg.2023.28. Online ahead of print.ABSTRACTThe purpose of this research was to determine the frequency of mutation of the cytochrome CYP3A5 genes and transport proteins SLCO1B1 and MDR1 in patients with coronary heart disease in the Kazakh nation. A prospective cohort clinical and genetic study was conducted. The study was conducted in 2017-2019. Medical records containing information about drug prescription conducted in hospitals and outpatient departments were carefully analyzed. In the examined group of 178 patients treated with statins, a significant frequency of geneti...
Source: Twin Research and Human Genetics - July 25, 2023 Category: Genetics & Stem Cells Authors: Raikhan Y Tuleutayeva Assem R Makhatova Saule O Rakhyzhanova Lashyn K Zhazykbayeva Dana K Kozhakhmetova Source Type: research

Candidate Genes for Prediction of Efficacy and Safety of Statin Therapy in the Kazakh Population
Twin Res Hum Genet. 2023 Jul 25:1-7. doi: 10.1017/thg.2023.28. Online ahead of print.ABSTRACTThe purpose of this research was to determine the frequency of mutation of the cytochrome CYP3A5 genes and transport proteins SLCO1B1 and MDR1 in patients with coronary heart disease in the Kazakh nation. A prospective cohort clinical and genetic study was conducted. The study was conducted in 2017-2019. Medical records containing information about drug prescription conducted in hospitals and outpatient departments were carefully analyzed. In the examined group of 178 patients treated with statins, a significant frequency of geneti...
Source: Twin Research and Human Genetics - July 25, 2023 Category: Genetics & Stem Cells Authors: Raikhan Y Tuleutayeva Assem R Makhatova Saule O Rakhyzhanova Lashyn K Zhazykbayeva Dana K Kozhakhmetova Source Type: research

Candidate Genes for Prediction of Efficacy and Safety of Statin Therapy in the Kazakh Population
Twin Res Hum Genet. 2023 Jul 25:1-7. doi: 10.1017/thg.2023.28. Online ahead of print.ABSTRACTThe purpose of this research was to determine the frequency of mutation of the cytochrome CYP3A5 genes and transport proteins SLCO1B1 and MDR1 in patients with coronary heart disease in the Kazakh nation. A prospective cohort clinical and genetic study was conducted. The study was conducted in 2017-2019. Medical records containing information about drug prescription conducted in hospitals and outpatient departments were carefully analyzed. In the examined group of 178 patients treated with statins, a significant frequency of geneti...
Source: Twin Research and Human Genetics - July 25, 2023 Category: Genetics & Stem Cells Authors: Raikhan Y Tuleutayeva Assem R Makhatova Saule O Rakhyzhanova Lashyn K Zhazykbayeva Dana K Kozhakhmetova Source Type: research

Candidate Genes for Prediction of Efficacy and Safety of Statin Therapy in the Kazakh Population
Twin Res Hum Genet. 2023 Jul 25:1-7. doi: 10.1017/thg.2023.28. Online ahead of print.ABSTRACTThe purpose of this research was to determine the frequency of mutation of the cytochrome CYP3A5 genes and transport proteins SLCO1B1 and MDR1 in patients with coronary heart disease in the Kazakh nation. A prospective cohort clinical and genetic study was conducted. The study was conducted in 2017-2019. Medical records containing information about drug prescription conducted in hospitals and outpatient departments were carefully analyzed. In the examined group of 178 patients treated with statins, a significant frequency of geneti...
Source: Twin Research and Human Genetics - July 25, 2023 Category: Genetics & Stem Cells Authors: Raikhan Y Tuleutayeva Assem R Makhatova Saule O Rakhyzhanova Lashyn K Zhazykbayeva Dana K Kozhakhmetova Source Type: research

Candidate Genes for Prediction of Efficacy and Safety of Statin Therapy in the Kazakh Population
Twin Res Hum Genet. 2023 Jul 25:1-7. doi: 10.1017/thg.2023.28. Online ahead of print.ABSTRACTThe purpose of this research was to determine the frequency of mutation of the cytochrome CYP3A5 genes and transport proteins SLCO1B1 and MDR1 in patients with coronary heart disease in the Kazakh nation. A prospective cohort clinical and genetic study was conducted. The study was conducted in 2017-2019. Medical records containing information about drug prescription conducted in hospitals and outpatient departments were carefully analyzed. In the examined group of 178 patients treated with statins, a significant frequency of geneti...
Source: Twin Research and Human Genetics - July 25, 2023 Category: Genetics & Stem Cells Authors: Raikhan Y Tuleutayeva Assem R Makhatova Saule O Rakhyzhanova Lashyn K Zhazykbayeva Dana K Kozhakhmetova Source Type: research

Candidate Genes for Prediction of Efficacy and Safety of Statin Therapy in the Kazakh Population
Twin Res Hum Genet. 2023 Jul 25:1-7. doi: 10.1017/thg.2023.28. Online ahead of print.ABSTRACTThe purpose of this research was to determine the frequency of mutation of the cytochrome CYP3A5 genes and transport proteins SLCO1B1 and MDR1 in patients with coronary heart disease in the Kazakh nation. A prospective cohort clinical and genetic study was conducted. The study was conducted in 2017-2019. Medical records containing information about drug prescription conducted in hospitals and outpatient departments were carefully analyzed. In the examined group of 178 patients treated with statins, a significant frequency of geneti...
Source: Twin Research and Human Genetics - July 25, 2023 Category: Genetics & Stem Cells Authors: Raikhan Y Tuleutayeva Assem R Makhatova Saule O Rakhyzhanova Lashyn K Zhazykbayeva Dana K Kozhakhmetova Source Type: research