Exploring Hematological and Biochemical Disparities in Same-Sex and Opposite-Sex Females: A Cross-Sectional Twin Study in a Ghanaian Population
Twin Res Hum Genet. 2024 Mar 6:1-6. doi: 10.1017/thg.2024.7. Online ahead of print.ABSTRACTThere are sex-dependent differences in hematological and biochemical variables in adulthood attributed to the predominant effects of testosterone in males and estrogen in females. The Twin Testosterone Transfer (TTT) hypothesis proposes that opposite-sex females may develop male-typical traits due to exposure to relatively higher levels of prenatal testosterone than same-sex females. Additionally, prenatal testosterone exposure has been suggested as a correlate of current circulating testosterone levels. Consequently, opposite-sex fe...
Source: Twin Research and Human Genetics - March 6, 2024 Category: Genetics & Stem Cells Authors: Moses Banyeh Benjamin N Mayeem Moses Kofi Woli Augusta S Kolekang Clement Binwatin Dagungong David Bure Romarick Kofi Wemegah Mikail Ihsan Azindow Suleman Yakubu Musah Seidu Mohammed Madde Baba Elisha Essoun Nancy Owireduwaa Source Type: research
Evolutionary Trends of Polygenic Scores in European Populations From the Paleolithic to Modern Times
This study examines the temporal and geographical evolution of polygenic scores (PGSs) across cognitive measures (Educational Attainment [EA], Intelligence Quotient [IQ]), Socioeconomic Status (SES), and psychiatric conditions (Autism Spectrum Disorder [ASD], schizophrenia [SCZ]) in various populations. Our findings indicate positive directional selection for EA, IQ, and SES traits over the past 12,000 years. Schizophrenia and autism, while similar, showed different temporal patterns, aligning with theories suggesting they are psychological opposites. We observed a decline in PGS for neuroticism and depression, likely due ...
Source: Twin Research and Human Genetics - March 6, 2024 Category: Genetics & Stem Cells Authors: Davide Piffer Emil O W Kirkegaard Source Type: research
Exploring Hematological and Biochemical Disparities in Same-Sex and Opposite-Sex Females: A Cross-Sectional Twin Study in a Ghanaian Population
Twin Res Hum Genet. 2024 Mar 6:1-6. doi: 10.1017/thg.2024.7. Online ahead of print.ABSTRACTThere are sex-dependent differences in hematological and biochemical variables in adulthood attributed to the predominant effects of testosterone in males and estrogen in females. The Twin Testosterone Transfer (TTT) hypothesis proposes that opposite-sex females may develop male-typical traits due to exposure to relatively higher levels of prenatal testosterone than same-sex females. Additionally, prenatal testosterone exposure has been suggested as a correlate of current circulating testosterone levels. Consequently, opposite-sex fe...
Source: Twin Research and Human Genetics - March 6, 2024 Category: Genetics & Stem Cells Authors: Moses Banyeh Benjamin N Mayeem Moses Kofi Woli Augusta S Kolekang Clement Binwatin Dagungong David Bure Romarick Kofi Wemegah Mikail Ihsan Azindow Suleman Yakubu Musah Seidu Mohammed Madde Baba Elisha Essoun Nancy Owireduwaa Source Type: research
Evolutionary Trends of Polygenic Scores in European Populations From the Paleolithic to Modern Times
This study examines the temporal and geographical evolution of polygenic scores (PGSs) across cognitive measures (Educational Attainment [EA], Intelligence Quotient [IQ]), Socioeconomic Status (SES), and psychiatric conditions (Autism Spectrum Disorder [ASD], schizophrenia [SCZ]) in various populations. Our findings indicate positive directional selection for EA, IQ, and SES traits over the past 12,000 years. Schizophrenia and autism, while similar, showed different temporal patterns, aligning with theories suggesting they are psychological opposites. We observed a decline in PGS for neuroticism and depression, likely due ...
Source: Twin Research and Human Genetics - March 6, 2024 Category: Genetics & Stem Cells Authors: Davide Piffer Emil O W Kirkegaard Source Type: research
Exploring Hematological and Biochemical Disparities in Same-Sex and Opposite-Sex Females: A Cross-Sectional Twin Study in a Ghanaian Population
Twin Res Hum Genet. 2024 Mar 6:1-6. doi: 10.1017/thg.2024.7. Online ahead of print.ABSTRACTThere are sex-dependent differences in hematological and biochemical variables in adulthood attributed to the predominant effects of testosterone in males and estrogen in females. The Twin Testosterone Transfer (TTT) hypothesis proposes that opposite-sex females may develop male-typical traits due to exposure to relatively higher levels of prenatal testosterone than same-sex females. Additionally, prenatal testosterone exposure has been suggested as a correlate of current circulating testosterone levels. Consequently, opposite-sex fe...
Source: Twin Research and Human Genetics - March 6, 2024 Category: Genetics & Stem Cells Authors: Moses Banyeh Benjamin N Mayeem Moses Kofi Woli Augusta S Kolekang Clement Binwatin Dagungong David Bure Romarick Kofi Wemegah Mikail Ihsan Azindow Suleman Yakubu Musah Seidu Mohammed Madde Baba Elisha Essoun Nancy Owireduwaa Source Type: research
Evolutionary Trends of Polygenic Scores in European Populations From the Paleolithic to Modern Times
This study examines the temporal and geographical evolution of polygenic scores (PGSs) across cognitive measures (Educational Attainment [EA], Intelligence Quotient [IQ]), Socioeconomic Status (SES), and psychiatric conditions (Autism Spectrum Disorder [ASD], schizophrenia [SCZ]) in various populations. Our findings indicate positive directional selection for EA, IQ, and SES traits over the past 12,000 years. Schizophrenia and autism, while similar, showed different temporal patterns, aligning with theories suggesting they are psychological opposites. We observed a decline in PGS for neuroticism and depression, likely due ...
Source: Twin Research and Human Genetics - March 6, 2024 Category: Genetics & Stem Cells Authors: Davide Piffer Emil O W Kirkegaard Source Type: research
Exploring Hematological and Biochemical Disparities in Same-Sex and Opposite-Sex Females: A Cross-Sectional Twin Study in a Ghanaian Population
Twin Res Hum Genet. 2024 Mar 6:1-6. doi: 10.1017/thg.2024.7. Online ahead of print.ABSTRACTThere are sex-dependent differences in hematological and biochemical variables in adulthood attributed to the predominant effects of testosterone in males and estrogen in females. The Twin Testosterone Transfer (TTT) hypothesis proposes that opposite-sex females may develop male-typical traits due to exposure to relatively higher levels of prenatal testosterone than same-sex females. Additionally, prenatal testosterone exposure has been suggested as a correlate of current circulating testosterone levels. Consequently, opposite-sex fe...
Source: Twin Research and Human Genetics - March 6, 2024 Category: Genetics & Stem Cells Authors: Moses Banyeh Benjamin N Mayeem Moses Kofi Woli Augusta S Kolekang Clement Binwatin Dagungong David Bure Romarick Kofi Wemegah Mikail Ihsan Azindow Suleman Yakubu Musah Seidu Mohammed Madde Baba Elisha Essoun Nancy Owireduwaa Source Type: research
The Impossible Dream - Panmixia
This study starts with a simple model by which Hardy-Weinberg proportions are attained in a single generation while maintaining gene frequencies. The question of differentiating between random and non-random mating is explored by simulation. Sample mating proportions are generated using the model as base. The difficulty of differentiating between random and non-random mating is illustrated.PMID:38410078 | DOI:10.1017/thg.2024.6 (Source: Twin Research and Human Genetics)
Source: Twin Research and Human Genetics - February 27, 2024 Category: Genetics & Stem Cells Authors: Alan E Stark Source Type: research
The Impossible Dream - Panmixia
This study starts with a simple model by which Hardy-Weinberg proportions are attained in a single generation while maintaining gene frequencies. The question of differentiating between random and non-random mating is explored by simulation. Sample mating proportions are generated using the model as base. The difficulty of differentiating between random and non-random mating is illustrated.PMID:38410078 | DOI:10.1017/thg.2024.6 (Source: Twin Research and Human Genetics)
Source: Twin Research and Human Genetics - February 27, 2024 Category: Genetics & Stem Cells Authors: Alan E Stark Source Type: research
The Impossible Dream - Panmixia
This study starts with a simple model by which Hardy-Weinberg proportions are attained in a single generation while maintaining gene frequencies. The question of differentiating between random and non-random mating is explored by simulation. Sample mating proportions are generated using the model as base. The difficulty of differentiating between random and non-random mating is illustrated.PMID:38410078 | DOI:10.1017/thg.2024.6 (Source: Twin Research and Human Genetics)
Source: Twin Research and Human Genetics - February 27, 2024 Category: Genetics & Stem Cells Authors: Alan E Stark Source Type: research
The Impossible Dream - Panmixia
This study starts with a simple model by which Hardy-Weinberg proportions are attained in a single generation while maintaining gene frequencies. The question of differentiating between random and non-random mating is explored by simulation. Sample mating proportions are generated using the model as base. The difficulty of differentiating between random and non-random mating is illustrated.PMID:38410078 | DOI:10.1017/thg.2024.6 (Source: Twin Research and Human Genetics)
Source: Twin Research and Human Genetics - February 27, 2024 Category: Genetics & Stem Cells Authors: Alan E Stark Source Type: research
The Impossible Dream - Panmixia
This study starts with a simple model by which Hardy-Weinberg proportions are attained in a single generation while maintaining gene frequencies. The question of differentiating between random and non-random mating is explored by simulation. Sample mating proportions are generated using the model as base. The difficulty of differentiating between random and non-random mating is illustrated.PMID:38410078 | DOI:10.1017/thg.2024.6 (Source: Twin Research and Human Genetics)
Source: Twin Research and Human Genetics - February 27, 2024 Category: Genetics & Stem Cells Authors: Alan E Stark Source Type: research
The Impossible Dream - Panmixia
This study starts with a simple model by which Hardy-Weinberg proportions are attained in a single generation while maintaining gene frequencies. The question of differentiating between random and non-random mating is explored by simulation. Sample mating proportions are generated using the model as base. The difficulty of differentiating between random and non-random mating is illustrated.PMID:38410078 | DOI:10.1017/thg.2024.6 (Source: Twin Research and Human Genetics)
Source: Twin Research and Human Genetics - February 27, 2024 Category: Genetics & Stem Cells Authors: Alan E Stark Source Type: research
The Impossible Dream - Panmixia
This study starts with a simple model by which Hardy-Weinberg proportions are attained in a single generation while maintaining gene frequencies. The question of differentiating between random and non-random mating is explored by simulation. Sample mating proportions are generated using the model as base. The difficulty of differentiating between random and non-random mating is illustrated.PMID:38410078 | DOI:10.1017/thg.2024.6 (Source: Twin Research and Human Genetics)
Source: Twin Research and Human Genetics - February 27, 2024 Category: Genetics & Stem Cells Authors: Alan E Stark Source Type: research
Partnership with the University of S ão Paulo Panel of Twins: A Four-City Tour and More / Twin Research Reviews: Twin Research on Binge Eating; Twins' Physical Outcomes Linked to Different Diets; Working Conditions and Sickness Absence in Swedish Twins; Facial Morphology Differences in Monozygotic Twins / Human Interest and Importance : Michigan Family Forced to Adopt Their Own Twins; Ethics of Hiring a Surrogate to Bear Twins; Twin Survivors of the Israel-Hamas War; Twin Pregnancy with Double Uterus; Three Twin Pairs on Same Women's Soccer Team
This article begins with an overview of twin research in Brazil, initiated by the University of São Paulo Panel of Twins. I met with many new research collaborators and students while on a fall 2023 four-city lecture tour in that country. A meeting with a world-famous surgeon who recently separated craniopagus conjoined twin pairs is also described. This overview is followed by summaries of twin research on binge eating, twins' physical outcomes linked to different diets, working conditions and sickness absence in Swedish Twins and facial morphology differences in monozygotic twins. The final section of this article provi...
Source: Twin Research and Human Genetics - February 21, 2024 Category: Genetics & Stem Cells Authors: Nancy L Segal Source Type: research
