Models for evaluating glioblastoma invasion along white matter tracts
Trends Biotechnol. 2023 Oct 6:S0167-7799(23)00279-2. doi: 10.1016/j.tibtech.2023.09.005. Online ahead of print.ABSTRACTWhite matter tracts (WMs) are one of the main invasion paths of glioblastoma multiforme (GBM). The lack of ideal research models hinders our understanding of the details and mechanisms of GBM invasion along WMs. To date, many potential in vitro models have been reported; nerve fiber culture models and nanomaterial models are biocompatible, and the former have electrically active neurons. Brain slice culture models, organoid models, and microfluidic chip models can simulate the real brain and tumor microenv...
Source: Trends in Biotechnology - October 8, 2023 Category: Biotechnology Authors: Yao Li Jun Wang Si-Rong Song Sheng-Qing Lv Jian-Hua Qin Shi-Cang Yu Source Type: research

Cardiac multiscale bioimaging: from nano- through micro- to mesoscales
Trends Biotechnol. 2023 Oct 6:S0167-7799(23)00241-X. doi: 10.1016/j.tibtech.2023.08.007. Online ahead of print.ABSTRACTCardiac multiscale bioimaging is an emerging field that aims to provide a comprehensive understanding of the heart and its functions at various levels, from the molecular to the entire organ. It combines both physiologically and clinically relevant dimensions: from nano- and micrometer resolution imaging based on vibrational spectroscopy and high-resolution microscopy to assess molecular processes in cardiac cells and myocardial tissue, to mesoscale structural investigations to improve the understanding of...
Source: Trends in Biotechnology - October 8, 2023 Category: Biotechnology Authors: Elen Tolstik Stephan E Lehnart Christian Soeller Kristina Lorenz Leonardo Sacconi Source Type: research

Emerging programmable nuclease-based detection for food safety
Trends Biotechnol. 2023 Oct 6:S0167-7799(23)00280-9. doi: 10.1016/j.tibtech.2023.09.006. Online ahead of print.ABSTRACTFood safety issues are an important challenge across the world. Programmable nucleases are emerging as new tools because of their significant biological advantages. This forum article provides an overview of recent advances and challenges in the novel paradigm of programmable nuclease-based detection for food safety.PMID:37806898 | DOI:10.1016/j.tibtech.2023.09.006 (Source: Trends in Biotechnology)
Source: Trends in Biotechnology - October 8, 2023 Category: Biotechnology Authors: Yaru Li Jingyu Jia Shuli Man Shengying Ye Long Ma Source Type: research

Models for evaluating glioblastoma invasion along white matter tracts
Trends Biotechnol. 2023 Oct 6:S0167-7799(23)00279-2. doi: 10.1016/j.tibtech.2023.09.005. Online ahead of print.ABSTRACTWhite matter tracts (WMs) are one of the main invasion paths of glioblastoma multiforme (GBM). The lack of ideal research models hinders our understanding of the details and mechanisms of GBM invasion along WMs. To date, many potential in vitro models have been reported; nerve fiber culture models and nanomaterial models are biocompatible, and the former have electrically active neurons. Brain slice culture models, organoid models, and microfluidic chip models can simulate the real brain and tumor microenv...
Source: Trends in Biotechnology - October 8, 2023 Category: Biotechnology Authors: Yao Li Jun Wang Si-Rong Song Sheng-Qing Lv Jian-Hua Qin Shi-Cang Yu Source Type: research

Cardiac multiscale bioimaging: from nano- through micro- to mesoscales
Trends Biotechnol. 2023 Oct 6:S0167-7799(23)00241-X. doi: 10.1016/j.tibtech.2023.08.007. Online ahead of print.ABSTRACTCardiac multiscale bioimaging is an emerging field that aims to provide a comprehensive understanding of the heart and its functions at various levels, from the molecular to the entire organ. It combines both physiologically and clinically relevant dimensions: from nano- and micrometer resolution imaging based on vibrational spectroscopy and high-resolution microscopy to assess molecular processes in cardiac cells and myocardial tissue, to mesoscale structural investigations to improve the understanding of...
Source: Trends in Biotechnology - October 8, 2023 Category: Biotechnology Authors: Elen Tolstik Stephan E Lehnart Christian Soeller Kristina Lorenz Leonardo Sacconi Source Type: research

Emerging programmable nuclease-based detection for food safety
Trends Biotechnol. 2023 Oct 6:S0167-7799(23)00280-9. doi: 10.1016/j.tibtech.2023.09.006. Online ahead of print.ABSTRACTFood safety issues are an important challenge across the world. Programmable nucleases are emerging as new tools because of their significant biological advantages. This forum article provides an overview of recent advances and challenges in the novel paradigm of programmable nuclease-based detection for food safety.PMID:37806898 | DOI:10.1016/j.tibtech.2023.09.006 (Source: Trends in Biotechnology)
Source: Trends in Biotechnology - October 8, 2023 Category: Biotechnology Authors: Yaru Li Jingyu Jia Shuli Man Shengying Ye Long Ma Source Type: research

Models for evaluating glioblastoma invasion along white matter tracts
Trends Biotechnol. 2023 Oct 6:S0167-7799(23)00279-2. doi: 10.1016/j.tibtech.2023.09.005. Online ahead of print.ABSTRACTWhite matter tracts (WMs) are one of the main invasion paths of glioblastoma multiforme (GBM). The lack of ideal research models hinders our understanding of the details and mechanisms of GBM invasion along WMs. To date, many potential in vitro models have been reported; nerve fiber culture models and nanomaterial models are biocompatible, and the former have electrically active neurons. Brain slice culture models, organoid models, and microfluidic chip models can simulate the real brain and tumor microenv...
Source: Trends in Biotechnology - October 8, 2023 Category: Biotechnology Authors: Yao Li Jun Wang Si-Rong Song Sheng-Qing Lv Jian-Hua Qin Shi-Cang Yu Source Type: research

Cardiac multiscale bioimaging: from nano- through micro- to mesoscales
Trends Biotechnol. 2023 Oct 6:S0167-7799(23)00241-X. doi: 10.1016/j.tibtech.2023.08.007. Online ahead of print.ABSTRACTCardiac multiscale bioimaging is an emerging field that aims to provide a comprehensive understanding of the heart and its functions at various levels, from the molecular to the entire organ. It combines both physiologically and clinically relevant dimensions: from nano- and micrometer resolution imaging based on vibrational spectroscopy and high-resolution microscopy to assess molecular processes in cardiac cells and myocardial tissue, to mesoscale structural investigations to improve the understanding of...
Source: Trends in Biotechnology - October 8, 2023 Category: Biotechnology Authors: Elen Tolstik Stephan E Lehnart Christian Soeller Kristina Lorenz Leonardo Sacconi Source Type: research

Emerging programmable nuclease-based detection for food safety
Trends Biotechnol. 2023 Oct 6:S0167-7799(23)00280-9. doi: 10.1016/j.tibtech.2023.09.006. Online ahead of print.ABSTRACTFood safety issues are an important challenge across the world. Programmable nucleases are emerging as new tools because of their significant biological advantages. This forum article provides an overview of recent advances and challenges in the novel paradigm of programmable nuclease-based detection for food safety.PMID:37806898 | DOI:10.1016/j.tibtech.2023.09.006 (Source: Trends in Biotechnology)
Source: Trends in Biotechnology - October 8, 2023 Category: Biotechnology Authors: Yaru Li Jingyu Jia Shuli Man Shengying Ye Long Ma Source Type: research

Models for evaluating glioblastoma invasion along white matter tracts
Trends Biotechnol. 2023 Oct 6:S0167-7799(23)00279-2. doi: 10.1016/j.tibtech.2023.09.005. Online ahead of print.ABSTRACTWhite matter tracts (WMs) are one of the main invasion paths of glioblastoma multiforme (GBM). The lack of ideal research models hinders our understanding of the details and mechanisms of GBM invasion along WMs. To date, many potential in vitro models have been reported; nerve fiber culture models and nanomaterial models are biocompatible, and the former have electrically active neurons. Brain slice culture models, organoid models, and microfluidic chip models can simulate the real brain and tumor microenv...
Source: Trends in Biotechnology - October 8, 2023 Category: Biotechnology Authors: Yao Li Jun Wang Si-Rong Song Sheng-Qing Lv Jian-Hua Qin Shi-Cang Yu Source Type: research

Cardiac multiscale bioimaging: from nano- through micro- to mesoscales
Trends Biotechnol. 2023 Oct 6:S0167-7799(23)00241-X. doi: 10.1016/j.tibtech.2023.08.007. Online ahead of print.ABSTRACTCardiac multiscale bioimaging is an emerging field that aims to provide a comprehensive understanding of the heart and its functions at various levels, from the molecular to the entire organ. It combines both physiologically and clinically relevant dimensions: from nano- and micrometer resolution imaging based on vibrational spectroscopy and high-resolution microscopy to assess molecular processes in cardiac cells and myocardial tissue, to mesoscale structural investigations to improve the understanding of...
Source: Trends in Biotechnology - October 8, 2023 Category: Biotechnology Authors: Elen Tolstik Stephan E Lehnart Christian Soeller Kristina Lorenz Leonardo Sacconi Source Type: research

Emerging programmable nuclease-based detection for food safety
Trends Biotechnol. 2023 Oct 6:S0167-7799(23)00280-9. doi: 10.1016/j.tibtech.2023.09.006. Online ahead of print.ABSTRACTFood safety issues are an important challenge across the world. Programmable nucleases are emerging as new tools because of their significant biological advantages. This forum article provides an overview of recent advances and challenges in the novel paradigm of programmable nuclease-based detection for food safety.PMID:37806898 | DOI:10.1016/j.tibtech.2023.09.006 (Source: Trends in Biotechnology)
Source: Trends in Biotechnology - October 8, 2023 Category: Biotechnology Authors: Yaru Li Jingyu Jia Shuli Man Shengying Ye Long Ma Source Type: research

Models for evaluating glioblastoma invasion along white matter tracts
Trends Biotechnol. 2023 Oct 6:S0167-7799(23)00279-2. doi: 10.1016/j.tibtech.2023.09.005. Online ahead of print.ABSTRACTWhite matter tracts (WMs) are one of the main invasion paths of glioblastoma multiforme (GBM). The lack of ideal research models hinders our understanding of the details and mechanisms of GBM invasion along WMs. To date, many potential in vitro models have been reported; nerve fiber culture models and nanomaterial models are biocompatible, and the former have electrically active neurons. Brain slice culture models, organoid models, and microfluidic chip models can simulate the real brain and tumor microenv...
Source: Trends in Biotechnology - October 8, 2023 Category: Biotechnology Authors: Yao Li Jun Wang Si-Rong Song Sheng-Qing Lv Jian-Hua Qin Shi-Cang Yu Source Type: research

Cardiac multiscale bioimaging: from nano- through micro- to mesoscales
Trends Biotechnol. 2023 Oct 6:S0167-7799(23)00241-X. doi: 10.1016/j.tibtech.2023.08.007. Online ahead of print.ABSTRACTCardiac multiscale bioimaging is an emerging field that aims to provide a comprehensive understanding of the heart and its functions at various levels, from the molecular to the entire organ. It combines both physiologically and clinically relevant dimensions: from nano- and micrometer resolution imaging based on vibrational spectroscopy and high-resolution microscopy to assess molecular processes in cardiac cells and myocardial tissue, to mesoscale structural investigations to improve the understanding of...
Source: Trends in Biotechnology - October 8, 2023 Category: Biotechnology Authors: Elen Tolstik Stephan E Lehnart Christian Soeller Kristina Lorenz Leonardo Sacconi Source Type: research

Emerging programmable nuclease-based detection for food safety
Trends Biotechnol. 2023 Oct 6:S0167-7799(23)00280-9. doi: 10.1016/j.tibtech.2023.09.006. Online ahead of print.ABSTRACTFood safety issues are an important challenge across the world. Programmable nucleases are emerging as new tools because of their significant biological advantages. This forum article provides an overview of recent advances and challenges in the novel paradigm of programmable nuclease-based detection for food safety.PMID:37806898 | DOI:10.1016/j.tibtech.2023.09.006 (Source: Trends in Biotechnology)
Source: Trends in Biotechnology - October 8, 2023 Category: Biotechnology Authors: Yaru Li Jingyu Jia Shuli Man Shengying Ye Long Ma Source Type: research