Enhancing the palatability of cultivated meat
Trends Biotechnol. 2024 Mar 26:S0167-7799(24)00062-3. doi: 10.1016/j.tibtech.2024.02.014. Online ahead of print.ABSTRACTCultivated meat (CM) has transitioned from a futuristic concept to a present reality, with select products approved for consumption and sale in Singapore, Israel, and the USA. This evolution has emphasized scalable, cost-effective, and sustainable production, as well as navigation of regulatory pathways. As CM develops, a crucial challenge lies in delivering products that are highly appealing to consumers. Central to this will be refining CM palatability, a term encompassing food's taste, aroma, texture, ...
Source: Trends in Biotechnology - March 26, 2024 Category: Biotechnology Authors: Ella G Lambert Christopher J O'Keeffe Alexander O Ward Tim A Anderson Queenie Yip Peter L H Newman Source Type: research
Enhancing the palatability of cultivated meat
Trends Biotechnol. 2024 Mar 26:S0167-7799(24)00062-3. doi: 10.1016/j.tibtech.2024.02.014. Online ahead of print.ABSTRACTCultivated meat (CM) has transitioned from a futuristic concept to a present reality, with select products approved for consumption and sale in Singapore, Israel, and the USA. This evolution has emphasized scalable, cost-effective, and sustainable production, as well as navigation of regulatory pathways. As CM develops, a crucial challenge lies in delivering products that are highly appealing to consumers. Central to this will be refining CM palatability, a term encompassing food's taste, aroma, texture, ...
Source: Trends in Biotechnology - March 26, 2024 Category: Biotechnology Authors: Ella G Lambert Christopher J O'Keeffe Alexander O Ward Tim A Anderson Queenie Yip Peter L H Newman Source Type: research
Emerging biotechnological applications of anaerobic ammonium oxidation
Trends Biotechnol. 2024 Mar 21:S0167-7799(24)00061-1. doi: 10.1016/j.tibtech.2024.02.013. Online ahead of print.ABSTRACTAnaerobic ammonium oxidation (anammox) is an energy-efficient method for nitrogen removal that opens the possibility for energy-neutral wastewater treatment. Research on anammox over the past decade has primarily focused on its implementation in domestic wastewater treatment. However, emerging studies are now expanding its use to novel biotechnological applications and wastewater treatment processes. This review highlights recent advances in the anammox field that aim to overcome conventional bottlenecks,...
Source: Trends in Biotechnology - March 22, 2024 Category: Biotechnology Authors: Dario Rangel Shaw Julian Tobon Gonzalez Carlos Bibiano Guadarrama Pascal E Saikaly Source Type: research
Emerging biotechnological applications of anaerobic ammonium oxidation
Trends Biotechnol. 2024 Mar 21:S0167-7799(24)00061-1. doi: 10.1016/j.tibtech.2024.02.013. Online ahead of print.ABSTRACTAnaerobic ammonium oxidation (anammox) is an energy-efficient method for nitrogen removal that opens the possibility for energy-neutral wastewater treatment. Research on anammox over the past decade has primarily focused on its implementation in domestic wastewater treatment. However, emerging studies are now expanding its use to novel biotechnological applications and wastewater treatment processes. This review highlights recent advances in the anammox field that aim to overcome conventional bottlenecks,...
Source: Trends in Biotechnology - March 22, 2024 Category: Biotechnology Authors: Dario Rangel Shaw Julian Tobon Gonzalez Carlos Bibiano Guadarrama Pascal E Saikaly Source Type: research
Emerging biotechnological applications of anaerobic ammonium oxidation
Trends Biotechnol. 2024 Mar 21:S0167-7799(24)00061-1. doi: 10.1016/j.tibtech.2024.02.013. Online ahead of print.ABSTRACTAnaerobic ammonium oxidation (anammox) is an energy-efficient method for nitrogen removal that opens the possibility for energy-neutral wastewater treatment. Research on anammox over the past decade has primarily focused on its implementation in domestic wastewater treatment. However, emerging studies are now expanding its use to novel biotechnological applications and wastewater treatment processes. This review highlights recent advances in the anammox field that aim to overcome conventional bottlenecks,...
Source: Trends in Biotechnology - March 22, 2024 Category: Biotechnology Authors: Dario Rangel Shaw Julian Tobon Gonzalez Carlos Bibiano Guadarrama Pascal E Saikaly Source Type: research
Mini-bones: miniaturized bone in vitro models
Trends Biotechnol. 2024 Mar 15:S0167-7799(24)00004-0. doi: 10.1016/j.tibtech.2024.01.004. Online ahead of print.ABSTRACTIn bone tissue engineering (TE) and regeneration, miniaturized, (sub)millimeter-sized bone models have become a popular trend since they bring about physiological biomimicry, precise orchestration of concurrent stimuli, and compatibility with high-throughput setups and high-content imaging. They also allow efficient use of cells, reagents, materials, and energy. In this review, we describe the state of the art of miniaturized in vitro bone models, or 'mini-bones', describing these models based on their ch...
Source: Trends in Biotechnology - March 16, 2024 Category: Biotechnology Authors: Maria Gabriella Fois Martijn van Griensven Stefan Giselbrecht Pamela Habibovi ć Roman K Truckenm üller Zeinab Niloofar Tahmasebi Birgani Source Type: research
CRISPR activation screens: navigating technologies and applications
Trends Biotechnol. 2024 Mar 15:S0167-7799(24)00036-2. doi: 10.1016/j.tibtech.2024.02.007. Online ahead of print.ABSTRACTClustered regularly interspaced short palindromic repeats (CRISPR) activation (CRISPRa) has become an integral part of the molecular biology toolkit. CRISPRa genetic screens are an exciting high-throughput means of identifying genes the upregulation of which is sufficient to elicit a given phenotype. Activation machinery is continually under development to achieve greater, more robust, and more consistent activation. In this review, we offer a succinct technological overview of available CRISPRa architect...
Source: Trends in Biotechnology - March 16, 2024 Category: Biotechnology Authors: Teleri Clark Matthew A Waller Lipin Loo Cesar L Moreno Christopher E Denes G Gregory Neely Source Type: research
Mini-bones: miniaturized bone in vitro models
Trends Biotechnol. 2024 Mar 15:S0167-7799(24)00004-0. doi: 10.1016/j.tibtech.2024.01.004. Online ahead of print.ABSTRACTIn bone tissue engineering (TE) and regeneration, miniaturized, (sub)millimeter-sized bone models have become a popular trend since they bring about physiological biomimicry, precise orchestration of concurrent stimuli, and compatibility with high-throughput setups and high-content imaging. They also allow efficient use of cells, reagents, materials, and energy. In this review, we describe the state of the art of miniaturized in vitro bone models, or 'mini-bones', describing these models based on their ch...
Source: Trends in Biotechnology - March 16, 2024 Category: Biotechnology Authors: Maria Gabriella Fois Martijn van Griensven Stefan Giselbrecht Pamela Habibovi ć Roman K Truckenm üller Zeinab Niloofar Tahmasebi Birgani Source Type: research
CRISPR activation screens: navigating technologies and applications
Trends Biotechnol. 2024 Mar 15:S0167-7799(24)00036-2. doi: 10.1016/j.tibtech.2024.02.007. Online ahead of print.ABSTRACTClustered regularly interspaced short palindromic repeats (CRISPR) activation (CRISPRa) has become an integral part of the molecular biology toolkit. CRISPRa genetic screens are an exciting high-throughput means of identifying genes the upregulation of which is sufficient to elicit a given phenotype. Activation machinery is continually under development to achieve greater, more robust, and more consistent activation. In this review, we offer a succinct technological overview of available CRISPRa architect...
Source: Trends in Biotechnology - March 16, 2024 Category: Biotechnology Authors: Teleri Clark Matthew A Waller Lipin Loo Cesar L Moreno Christopher E Denes G Gregory Neely Source Type: research
Mini-bones: miniaturized bone in vitro models
Trends Biotechnol. 2024 Mar 15:S0167-7799(24)00004-0. doi: 10.1016/j.tibtech.2024.01.004. Online ahead of print.ABSTRACTIn bone tissue engineering (TE) and regeneration, miniaturized, (sub)millimeter-sized bone models have become a popular trend since they bring about physiological biomimicry, precise orchestration of concurrent stimuli, and compatibility with high-throughput setups and high-content imaging. They also allow efficient use of cells, reagents, materials, and energy. In this review, we describe the state of the art of miniaturized in vitro bone models, or 'mini-bones', describing these models based on their ch...
Source: Trends in Biotechnology - March 16, 2024 Category: Biotechnology Authors: Maria Gabriella Fois Martijn van Griensven Stefan Giselbrecht Pamela Habibovi ć Roman K Truckenm üller Zeinab Niloofar Tahmasebi Birgani Source Type: research
CRISPR activation screens: navigating technologies and applications
Trends Biotechnol. 2024 Mar 15:S0167-7799(24)00036-2. doi: 10.1016/j.tibtech.2024.02.007. Online ahead of print.ABSTRACTClustered regularly interspaced short palindromic repeats (CRISPR) activation (CRISPRa) has become an integral part of the molecular biology toolkit. CRISPRa genetic screens are an exciting high-throughput means of identifying genes the upregulation of which is sufficient to elicit a given phenotype. Activation machinery is continually under development to achieve greater, more robust, and more consistent activation. In this review, we offer a succinct technological overview of available CRISPRa architect...
Source: Trends in Biotechnology - March 16, 2024 Category: Biotechnology Authors: Teleri Clark Matthew A Waller Lipin Loo Cesar L Moreno Christopher E Denes G Gregory Neely Source Type: research
Mini-bones: miniaturized bone in vitro models
Trends Biotechnol. 2024 Mar 15:S0167-7799(24)00004-0. doi: 10.1016/j.tibtech.2024.01.004. Online ahead of print.ABSTRACTIn bone tissue engineering (TE) and regeneration, miniaturized, (sub)millimeter-sized bone models have become a popular trend since they bring about physiological biomimicry, precise orchestration of concurrent stimuli, and compatibility with high-throughput setups and high-content imaging. They also allow efficient use of cells, reagents, materials, and energy. In this review, we describe the state of the art of miniaturized in vitro bone models, or 'mini-bones', describing these models based on their ch...
Source: Trends in Biotechnology - March 16, 2024 Category: Biotechnology Authors: Maria Gabriella Fois Martijn van Griensven Stefan Giselbrecht Pamela Habibovi ć Roman K Truckenm üller Zeinab Niloofar Tahmasebi Birgani Source Type: research
CRISPR activation screens: navigating technologies and applications
Trends Biotechnol. 2024 Mar 15:S0167-7799(24)00036-2. doi: 10.1016/j.tibtech.2024.02.007. Online ahead of print.ABSTRACTClustered regularly interspaced short palindromic repeats (CRISPR) activation (CRISPRa) has become an integral part of the molecular biology toolkit. CRISPRa genetic screens are an exciting high-throughput means of identifying genes the upregulation of which is sufficient to elicit a given phenotype. Activation machinery is continually under development to achieve greater, more robust, and more consistent activation. In this review, we offer a succinct technological overview of available CRISPRa architect...
Source: Trends in Biotechnology - March 16, 2024 Category: Biotechnology Authors: Teleri Clark Matthew A Waller Lipin Loo Cesar L Moreno Christopher E Denes G Gregory Neely Source Type: research
Mini-bones: miniaturized bone in vitro models
Trends Biotechnol. 2024 Mar 15:S0167-7799(24)00004-0. doi: 10.1016/j.tibtech.2024.01.004. Online ahead of print.ABSTRACTIn bone tissue engineering (TE) and regeneration, miniaturized, (sub)millimeter-sized bone models have become a popular trend since they bring about physiological biomimicry, precise orchestration of concurrent stimuli, and compatibility with high-throughput setups and high-content imaging. They also allow efficient use of cells, reagents, materials, and energy. In this review, we describe the state of the art of miniaturized in vitro bone models, or 'mini-bones', describing these models based on their ch...
Source: Trends in Biotechnology - March 16, 2024 Category: Biotechnology Authors: Maria Gabriella Fois Martijn van Griensven Stefan Giselbrecht Pamela Habibovi ć Roman K Truckenm üller Zeinab Niloofar Tahmasebi Birgani Source Type: research
CRISPR activation screens: navigating technologies and applications
Trends Biotechnol. 2024 Mar 15:S0167-7799(24)00036-2. doi: 10.1016/j.tibtech.2024.02.007. Online ahead of print.ABSTRACTClustered regularly interspaced short palindromic repeats (CRISPR) activation (CRISPRa) has become an integral part of the molecular biology toolkit. CRISPRa genetic screens are an exciting high-throughput means of identifying genes the upregulation of which is sufficient to elicit a given phenotype. Activation machinery is continually under development to achieve greater, more robust, and more consistent activation. In this review, we offer a succinct technological overview of available CRISPRa architect...
Source: Trends in Biotechnology - March 16, 2024 Category: Biotechnology Authors: Teleri Clark Matthew A Waller Lipin Loo Cesar L Moreno Christopher E Denes G Gregory Neely Source Type: research
