Conducting polymer scaffolds: a new frontier in bioelectronics and bioengineering
Trends Biotechnol. 2024 Jan 5:S0167-7799(23)00339-6. doi: 10.1016/j.tibtech.2023.11.017. Online ahead of print.ABSTRACTConducting polymer (CP) scaffolds have emerged as a transformative tool in bioelectronics and bioengineering, advancing the ability to interface with biological systems. Their unique combination of electrical conductivity, tailorability, and biocompatibility surpasses the capabilities of traditional nonconducting scaffolds while granting them access to the realm of bioelectronics. This review examines recent developments in CP scaffolds, focusing on material and device advancements, as well as their interp...
Source: Trends in Biotechnology - January 6, 2024 Category: Biotechnology Authors: Rasha A Nasser Sagar S Arya Khulood H Alshehhi Jeremy C M Teo Charalampos Pitsalidis Source Type: research

Harnessing Pseudomonas putida in bioelectrochemical systems
Trends Biotechnol. 2024 Jan 5:S0167-7799(23)00341-4. doi: 10.1016/j.tibtech.2023.12.002. Online ahead of print.ABSTRACTBioelectrochemical systems (BESs), a group of promising integrated systems that combine the advantages of biotechnology and electrochemical techniques, offer new opportunities to address environmental and energy challenges. Exoelectrogens capable of extracellular electron transfer (EET) are the critical factor enabling electrocatalytic activity in BESs. Pseudomonas putida, an aerobe widely used in environmental bioremediation, the biosynthesis of valuable chemicals, and energy bioproduction, has attracted ...
Source: Trends in Biotechnology - January 6, 2024 Category: Biotechnology Authors: Xiaoyan Qi Xinyu Gao Xia Wang Ping Xu Source Type: research

Understanding phycosomal dynamics to improve industrial microalgae cultivation
Trends Biotechnol. 2024 Jan 5:S0167-7799(23)00342-6. doi: 10.1016/j.tibtech.2023.12.003. Online ahead of print.ABSTRACTAlgal-bacterial interactions are ubiquitous in both natural and industrial systems, and the characterization of these interactions has been reinvigorated by potential applications in biosystem productivity. Different growth conditions can be used for operational functions, such as the use of low-quality water or high pH/alkalinity, and the altered operating conditions likely constrain microbial community structure and function in unique ways. However, research is necessary to better understand whether cons...
Source: Trends in Biotechnology - January 6, 2024 Category: Biotechnology Authors: Isaac R Miller Huyen Bui Jessica B Wood Matthew W Fields Robin Gerlach Source Type: research

Conducting polymer scaffolds: a new frontier in bioelectronics and bioengineering
Trends Biotechnol. 2024 Jan 5:S0167-7799(23)00339-6. doi: 10.1016/j.tibtech.2023.11.017. Online ahead of print.ABSTRACTConducting polymer (CP) scaffolds have emerged as a transformative tool in bioelectronics and bioengineering, advancing the ability to interface with biological systems. Their unique combination of electrical conductivity, tailorability, and biocompatibility surpasses the capabilities of traditional nonconducting scaffolds while granting them access to the realm of bioelectronics. This review examines recent developments in CP scaffolds, focusing on material and device advancements, as well as their interp...
Source: Trends in Biotechnology - January 6, 2024 Category: Biotechnology Authors: Rasha A Nasser Sagar S Arya Khulood H Alshehhi Jeremy C M Teo Charalampos Pitsalidis Source Type: research

Harnessing Pseudomonas putida in bioelectrochemical systems
Trends Biotechnol. 2024 Jan 5:S0167-7799(23)00341-4. doi: 10.1016/j.tibtech.2023.12.002. Online ahead of print.ABSTRACTBioelectrochemical systems (BESs), a group of promising integrated systems that combine the advantages of biotechnology and electrochemical techniques, offer new opportunities to address environmental and energy challenges. Exoelectrogens capable of extracellular electron transfer (EET) are the critical factor enabling electrocatalytic activity in BESs. Pseudomonas putida, an aerobe widely used in environmental bioremediation, the biosynthesis of valuable chemicals, and energy bioproduction, has attracted ...
Source: Trends in Biotechnology - January 6, 2024 Category: Biotechnology Authors: Xiaoyan Qi Xinyu Gao Xia Wang Ping Xu Source Type: research

Microbial products for space nutrition
Trends Biotechnol. 2024 Jan 4:S0167-7799(23)00343-8. doi: 10.1016/j.tibtech.2023.12.004. Online ahead of print.ABSTRACTSustainably producing nutrients beyond Earth is one of the biggest technical challenges for future extended human space missions. Microorganisms such as microalgae and cyanobacteria can provide astronauts with nutrients, pharmaceuticals, pure oxygen, and bio-based polymers, making them an interesting resource for constructing a circular bioregenerative life support system in space.PMID:38182440 | DOI:10.1016/j.tibtech.2023.12.004 (Source: Trends in Biotechnology)
Source: Trends in Biotechnology - January 5, 2024 Category: Biotechnology Authors: Cassamo U Mussagy Jorge F B Pereira Adalberto Pessoa Source Type: research

Make better, data-backed decisions to hit biotech milestones faster
Trends Biotechnol. 2023 Dec 19:S0167-7799(23)00333-5. doi: 10.1016/j.tibtech.2023.11.011. Online ahead of print.NO ABSTRACTPMID:38177026 | DOI:10.1016/j.tibtech.2023.11.011 (Source: Trends in Biotechnology)
Source: Trends in Biotechnology - January 4, 2024 Category: Biotechnology Authors: Mandana Manzari Honu Bogdan Knezevic David Yen Source Type: research

Make better, data-backed decisions to hit biotech milestones faster
Trends Biotechnol. 2023 Dec 19:S0167-7799(23)00333-5. doi: 10.1016/j.tibtech.2023.11.011. Online ahead of print.NO ABSTRACTPMID:38177026 | DOI:10.1016/j.tibtech.2023.11.011 (Source: Trends in Biotechnology)
Source: Trends in Biotechnology - January 4, 2024 Category: Biotechnology Authors: Mandana Manzari Honu Bogdan Knezevic David Yen Source Type: research

China's regulatory change toward genome-edited crops
Trends Biotechnol. 2023 Dec 30:S0167-7799(23)00347-5. doi: 10.1016/j.tibtech.2023.12.008. Online ahead of print.ABSTRACTChina's newly issued genome-edited crop safety assessment guidelines do not entirely deviate from the existing genetically modified regulatory regimes. However, there is an urgent need to reform the genome-edited regulatory framework based on scientific values and a novel regulatory philosophy that balances diverse values to enhance public trust.PMID:38160083 | DOI:10.1016/j.tibtech.2023.12.008 (Source: Trends in Biotechnology)
Source: Trends in Biotechnology - December 30, 2023 Category: Biotechnology Authors: Fei Yang Kaili Zheng Yu Yao Source Type: research

China's regulatory change toward genome-edited crops
Trends Biotechnol. 2023 Dec 30:S0167-7799(23)00347-5. doi: 10.1016/j.tibtech.2023.12.008. Online ahead of print.ABSTRACTChina's newly issued genome-edited crop safety assessment guidelines do not entirely deviate from the existing genetically modified regulatory regimes. However, there is an urgent need to reform the genome-edited regulatory framework based on scientific values and a novel regulatory philosophy that balances diverse values to enhance public trust.PMID:38160083 | DOI:10.1016/j.tibtech.2023.12.008 (Source: Trends in Biotechnology)
Source: Trends in Biotechnology - December 30, 2023 Category: Biotechnology Authors: Fei Yang Kaili Zheng Yu Yao Source Type: research

China's regulatory change toward genome-edited crops
Trends Biotechnol. 2023 Dec 30:S0167-7799(23)00347-5. doi: 10.1016/j.tibtech.2023.12.008. Online ahead of print.ABSTRACTChina's newly issued genome-edited crop safety assessment guidelines do not entirely deviate from the existing genetically modified regulatory regimes. However, there is an urgent need to reform the genome-edited regulatory framework based on scientific values and a novel regulatory philosophy that balances diverse values to enhance public trust.PMID:38160083 | DOI:10.1016/j.tibtech.2023.12.008 (Source: Trends in Biotechnology)
Source: Trends in Biotechnology - December 30, 2023 Category: Biotechnology Authors: Fei Yang Kaili Zheng Yu Yao Source Type: research

Drought-tolerant transgenic wheat HB4 ®: a hope for the future
Trends Biotechnol. 2023 Dec 28:S0167-7799(23)00346-3. doi: 10.1016/j.tibtech.2023.12.007. Online ahead of print.ABSTRACTDrought-tolerant transgenic [genetically modified (GM)] HB4® wheat carrying the drought-responsive sunflower gene Hahb4 was first developed in Argentina in 2019 and has already been approved for marketing and consumption as food/feed in at least ten countries. It has also been approved in Argentina and Brazil for commercial cultivation.PMID:38158306 | DOI:10.1016/j.tibtech.2023.12.007 (Source: Trends in Biotechnology)
Source: Trends in Biotechnology - December 29, 2023 Category: Biotechnology Authors: Pushpendra K Gupta Source Type: research

New dimensions of electrospun nanofiber material designs for biotechnological uses
Trends Biotechnol. 2023 Dec 28:S0167-7799(23)00330-X. doi: 10.1016/j.tibtech.2023.11.008. Online ahead of print.ABSTRACTElectrospinning technology has garnered wide attention over the past few decades in various biomedical applications including drug delivery, cell therapy, and tissue engineering. This technology can create nanofibers with tunable fiber diameters and functionalities. However, the 2D membrane nature of the nanofibers, as well as the rigidity and low porosity of electrospun fibers, lower their efficacy in tissue repair and regeneration. Recently, new avenues have been explored to resolve the challenges assoc...
Source: Trends in Biotechnology - December 29, 2023 Category: Biotechnology Authors: Meenakshi Kamaraj Nafiseh Moghimi Junjie Chen Ramon Morales Shixuan Chen Ali Khademhosseini Johnson V John Source Type: research

Chips, guts, and gas: unraveling volatile microbial mysteries in real time!
Trends Biotechnol. 2023 Dec 28:S0167-7799(23)00362-1. doi: 10.1016/j.tibtech.2023.12.009. Online ahead of print.ABSTRACTExploring the gastrointestinal role of hydrogen sulfide (H2S) is difficult because of its volatility and the absence of a precisely controllable model system for manipulating the gut environment. Hayes et al. address this issue by engineering Escherichia coli to titrate H2S levels in a gas-impermeable gut-on-chip device.PMID:38158308 | DOI:10.1016/j.tibtech.2023.12.009 (Source: Trends in Biotechnology)
Source: Trends in Biotechnology - December 29, 2023 Category: Biotechnology Authors: Zidan Li Nathan C Crook Source Type: research

Regulatory and governance gaps for human genome editing in Mexico
Trends Biotechnol. 2023 Dec 20:S0167-7799(23)00335-9. doi: 10.1016/j.tibtech.2023.11.013. Online ahead of print.ABSTRACTMexico has the in-house technical and regulatory capacity to undertake human genome editing (HGE) governance. However, its regulatory framework must be reformed to be more targeted and govern the application of any emerging HGE technologies, leaving no room for unethical or unsafe practices for reproductive purposes.PMID:38129214 | DOI:10.1016/j.tibtech.2023.11.013 (Source: Trends in Biotechnology)
Source: Trends in Biotechnology - December 21, 2023 Category: Biotechnology Authors: Guillermo Aquino-Jarquin Source Type: research