The lignocellulosic biorefinery concept is sound: a commentary on Zhao et al
Trends Biotechnol. 2023 Dec 20:S0167-7799(23)00344-X. doi: 10.1016/j.tibtech.2023.12.005. Online ahead of print.ABSTRACTIn the opinion paper by Zhao et al. 'Making the biochemical conversion of lignocellulose more robust', the authors claim that '…lignocellulose biorefinery is conceptually wrong'. In response, we argue that this claim itself has already been proved wrong by several companies.PMID:38129215 | DOI:10.1016/j.tibtech.2023.12.005 (Source: Trends in Biotechnology)
Source: Trends in Biotechnology - December 21, 2023 Category: Biotechnology Authors: Carl Johan Franz én Lisbeth Olsson Katja Salomon Johansen Source Type: research
Shaping the future US bioeconomy through safety, security, sustainability, and social responsibility
Trends Biotechnol. 2023 Dec 20:S0167-7799(23)00337-2. doi: 10.1016/j.tibtech.2023.11.015. Online ahead of print.ABSTRACTBiomanufacturing practitioners and researchers describe the norms that should govern the growing, global field, to include safety, security, sustainability, and social responsibility. These '4S Principles' should be broadly adopted so that the future of the field may provide the greatest benefits to society.PMID:38129216 | DOI:10.1016/j.tibtech.2023.11.015 (Source: Trends in Biotechnology)
Source: Trends in Biotechnology - December 21, 2023 Category: Biotechnology Authors: Aurelia Attal-Juncqua Galen Dods Nicole Crain James Diggans David Dodds Steve Evans Nick Fackler Kevin Flyangolts Kathleen Gibson Margaret E Kosal Aditya Kunjapur Russ Read Brian Renda Corinne D Scown Kissaou Tchedre Krista Ternus Beth Vitalis Gigi Gronva Source Type: research
Regulatory and governance gaps for human genome editing in Mexico
Trends Biotechnol. 2023 Dec 20:S0167-7799(23)00335-9. doi: 10.1016/j.tibtech.2023.11.013. Online ahead of print.ABSTRACTMexico has the in-house technical and regulatory capacity to undertake human genome editing (HGE) governance. However, its regulatory framework must be reformed to be more targeted and govern the application of any emerging HGE technologies, leaving no room for unethical or unsafe practices for reproductive purposes.PMID:38129214 | DOI:10.1016/j.tibtech.2023.11.013 (Source: Trends in Biotechnology)
Source: Trends in Biotechnology - December 21, 2023 Category: Biotechnology Authors: Guillermo Aquino-Jarquin Source Type: research
The lignocellulosic biorefinery concept is sound: a commentary on Zhao et al
Trends Biotechnol. 2023 Dec 20:S0167-7799(23)00344-X. doi: 10.1016/j.tibtech.2023.12.005. Online ahead of print.ABSTRACTIn the opinion paper by Zhao et al. 'Making the biochemical conversion of lignocellulose more robust', the authors claim that '…lignocellulose biorefinery is conceptually wrong'. In response, we argue that this claim itself has already been proved wrong by several companies.PMID:38129215 | DOI:10.1016/j.tibtech.2023.12.005 (Source: Trends in Biotechnology)
Source: Trends in Biotechnology - December 21, 2023 Category: Biotechnology Authors: Carl Johan Franz én Lisbeth Olsson Katja Salomon Johansen Source Type: research
Shaping the future US bioeconomy through safety, security, sustainability, and social responsibility
Trends Biotechnol. 2023 Dec 20:S0167-7799(23)00337-2. doi: 10.1016/j.tibtech.2023.11.015. Online ahead of print.ABSTRACTBiomanufacturing practitioners and researchers describe the norms that should govern the growing, global field, to include safety, security, sustainability, and social responsibility. These '4S Principles' should be broadly adopted so that the future of the field may provide the greatest benefits to society.PMID:38129216 | DOI:10.1016/j.tibtech.2023.11.015 (Source: Trends in Biotechnology)
Source: Trends in Biotechnology - December 21, 2023 Category: Biotechnology Authors: Aurelia Attal-Juncqua Galen Dods Nicole Crain James Diggans David Dodds Steve Evans Nick Fackler Kevin Flyangolts Kathleen Gibson Margaret E Kosal Aditya Kunjapur Russ Read Brian Renda Corinne D Scown Kissaou Tchedre Krista Ternus Beth Vitalis Gigi Gronva Source Type: research
From garages to ecosystems: the coevolution of life science incubators and accelerators
Trends Biotechnol. 2023 Dec 8:S0167-7799(23)00329-3. doi: 10.1016/j.tibtech.2023.11.007. Online ahead of print.ABSTRACTIncubators and accelerators catalyze the launch of life science startups and have evolved from simple facilities to vibrant ecosystems offering research infrastructure, programs, and funding. Analysis of financing activities indicates the outperformance of incubator companies relative to accelerators in fundraising, mergers and acquisitions (M&As), and initial public offerings (IPOs), attributed to extended interactions with investors and peers.PMID:38114392 | DOI:10.1016/j.tibtech.2023.11.007 (Source:...
Source: Trends in Biotechnology - December 19, 2023 Category: Biotechnology Authors: Widya Mulyasasmita David V Schaffer Risa Stack Rowan Chapman Source Type: research
From garages to ecosystems: the coevolution of life science incubators and accelerators
Trends Biotechnol. 2023 Dec 8:S0167-7799(23)00329-3. doi: 10.1016/j.tibtech.2023.11.007. Online ahead of print.ABSTRACTIncubators and accelerators catalyze the launch of life science startups and have evolved from simple facilities to vibrant ecosystems offering research infrastructure, programs, and funding. Analysis of financing activities indicates the outperformance of incubator companies relative to accelerators in fundraising, mergers and acquisitions (M&As), and initial public offerings (IPOs), attributed to extended interactions with investors and peers.PMID:38114392 | DOI:10.1016/j.tibtech.2023.11.007 (Source:...
Source: Trends in Biotechnology - December 19, 2023 Category: Biotechnology Authors: Widya Mulyasasmita David V Schaffer Risa Stack Rowan Chapman Source Type: research
Maximizing the benefits of biofilms in fermentation processes
Trends Biotechnol. 2023 Dec 15:S0167-7799(23)00334-7. doi: 10.1016/j.tibtech.2023.11.012. Online ahead of print.ABSTRACTBiofilm-based fermentation has great potential, as it possesses inherent characteristics such as self-immobilization, high resistance to reactants, and long-term activity. This forum focuses on research targets for promoting biofilm engineering to maximize the beneficial features of biofilms and to effectively utilize them in biofilm-mediated fermentation.PMID:38103978 | DOI:10.1016/j.tibtech.2023.11.012 (Source: Trends in Biotechnology)
Source: Trends in Biotechnology - December 16, 2023 Category: Biotechnology Authors: Anming Xu Fengxue Xin Weiliang Dong Min Jiang Source Type: research
Maximizing the benefits of biofilms in fermentation processes
Trends Biotechnol. 2023 Dec 15:S0167-7799(23)00334-7. doi: 10.1016/j.tibtech.2023.11.012. Online ahead of print.ABSTRACTBiofilm-based fermentation has great potential, as it possesses inherent characteristics such as self-immobilization, high resistance to reactants, and long-term activity. This forum focuses on research targets for promoting biofilm engineering to maximize the beneficial features of biofilms and to effectively utilize them in biofilm-mediated fermentation.PMID:38103978 | DOI:10.1016/j.tibtech.2023.11.012 (Source: Trends in Biotechnology)
Source: Trends in Biotechnology - December 16, 2023 Category: Biotechnology Authors: Anming Xu Fengxue Xin Weiliang Dong Min Jiang Source Type: research
Maximizing the benefits of biofilms in fermentation processes
Trends Biotechnol. 2023 Dec 15:S0167-7799(23)00334-7. doi: 10.1016/j.tibtech.2023.11.012. Online ahead of print.ABSTRACTBiofilm-based fermentation has great potential, as it possesses inherent characteristics such as self-immobilization, high resistance to reactants, and long-term activity. This forum focuses on research targets for promoting biofilm engineering to maximize the beneficial features of biofilms and to effectively utilize them in biofilm-mediated fermentation.PMID:38103978 | DOI:10.1016/j.tibtech.2023.11.012 (Source: Trends in Biotechnology)
Source: Trends in Biotechnology - December 16, 2023 Category: Biotechnology Authors: Anming Xu Fengxue Xin Weiliang Dong Min Jiang Source Type: research
Electrotransfer for nucleic acid and protein delivery
Trends Biotechnol. 2023 Dec 14:S0167-7799(23)00331-1. doi: 10.1016/j.tibtech.2023.11.009. Online ahead of print.ABSTRACTElectrotransfer of nucleic acids and proteins has become crucial in biotechnology for gene augmentation and genome editing. This review explores the applications of electrotransfer in both ex vivo and in vivo scenarios, emphasizing biomedical uses. We provide insights into completed clinical trials and successful instances of nucleic acid and protein electrotransfer into therapeutically relevant cells such as immune cells and stem and progenitor cells. In addition, we delve into emerging areas of electrot...
Source: Trends in Biotechnology - December 15, 2023 Category: Biotechnology Authors: Aswin Muralidharan Pouyan E Boukany Source Type: research
Electrotransfer for nucleic acid and protein delivery
Trends Biotechnol. 2023 Dec 14:S0167-7799(23)00331-1. doi: 10.1016/j.tibtech.2023.11.009. Online ahead of print.ABSTRACTElectrotransfer of nucleic acids and proteins has become crucial in biotechnology for gene augmentation and genome editing. This review explores the applications of electrotransfer in both ex vivo and in vivo scenarios, emphasizing biomedical uses. We provide insights into completed clinical trials and successful instances of nucleic acid and protein electrotransfer into therapeutically relevant cells such as immune cells and stem and progenitor cells. In addition, we delve into emerging areas of electrot...
Source: Trends in Biotechnology - December 15, 2023 Category: Biotechnology Authors: Aswin Muralidharan Pouyan E Boukany Source Type: research
Molecular design of microalgae as sustainable cell factories
Trends Biotechnol. 2023 Dec 12:S0167-7799(23)00332-3. doi: 10.1016/j.tibtech.2023.11.010. Online ahead of print.ABSTRACTMicroalgae are regarded as sustainable and potent chassis for biotechnology. Their capacity for efficient photosynthesis fuels dynamic growth independent from organic carbon sources and converts atmospheric CO2 directly into various valuable hydrocarbon-based metabolites. However, approaches to gene expression and metabolic regulation have been inferior to those in more established heterotrophs (e.g., prokaryotes or yeast) since the genetic tools and insights in expression regulation have been distinctly ...
Source: Trends in Biotechnology - December 13, 2023 Category: Biotechnology Authors: Alexander Einhaus Thomas Baier Olaf Kruse Source Type: research
Molecular design of microalgae as sustainable cell factories
Trends Biotechnol. 2023 Dec 12:S0167-7799(23)00332-3. doi: 10.1016/j.tibtech.2023.11.010. Online ahead of print.ABSTRACTMicroalgae are regarded as sustainable and potent chassis for biotechnology. Their capacity for efficient photosynthesis fuels dynamic growth independent from organic carbon sources and converts atmospheric CO2 directly into various valuable hydrocarbon-based metabolites. However, approaches to gene expression and metabolic regulation have been inferior to those in more established heterotrophs (e.g., prokaryotes or yeast) since the genetic tools and insights in expression regulation have been distinctly ...
Source: Trends in Biotechnology - December 13, 2023 Category: Biotechnology Authors: Alexander Einhaus Thomas Baier Olaf Kruse Source Type: research
Molecular design of microalgae as sustainable cell factories
Trends Biotechnol. 2023 Dec 12:S0167-7799(23)00332-3. doi: 10.1016/j.tibtech.2023.11.010. Online ahead of print.ABSTRACTMicroalgae are regarded as sustainable and potent chassis for biotechnology. Their capacity for efficient photosynthesis fuels dynamic growth independent from organic carbon sources and converts atmospheric CO2 directly into various valuable hydrocarbon-based metabolites. However, approaches to gene expression and metabolic regulation have been inferior to those in more established heterotrophs (e.g., prokaryotes or yeast) since the genetic tools and insights in expression regulation have been distinctly ...
Source: Trends in Biotechnology - December 13, 2023 Category: Biotechnology Authors: Alexander Einhaus Thomas Baier Olaf Kruse Source Type: research
