Synthetic control of living cells by intracellular polymerization
Trends Biotechnol. 2023 Sep 22:S0167-7799(23)00240-8. doi: 10.1016/j.tibtech.2023.08.006. Online ahead of print.ABSTRACTAn emerging cellular engineering method creates synthetic polymer matrices inside cells. By contrast with classical genetic, enzymatic, or radioactive techniques, this materials-based approach introduces non-natural polymers inside cells, thus modifying cellular states and functionalities. Here, we cover various materials and chemistries that have been exploited to create intracellular polymer matrices. In addition, we discuss emergent cellular properties due to the intracellular polymerization, including...
Source: Trends in Biotechnology - September 24, 2023 Category: Biotechnology Authors: Ofelya Baghdasaryan Shahid Khan Jung-Chen Lin Jared Lee-Kin Chung-Yao Hsu Che-Ming Jack Hu Cheemeng Tan Source Type: research
Synthetic control of living cells by intracellular polymerization
Trends Biotechnol. 2023 Sep 22:S0167-7799(23)00240-8. doi: 10.1016/j.tibtech.2023.08.006. Online ahead of print.ABSTRACTAn emerging cellular engineering method creates synthetic polymer matrices inside cells. By contrast with classical genetic, enzymatic, or radioactive techniques, this materials-based approach introduces non-natural polymers inside cells, thus modifying cellular states and functionalities. Here, we cover various materials and chemistries that have been exploited to create intracellular polymer matrices. In addition, we discuss emergent cellular properties due to the intracellular polymerization, including...
Source: Trends in Biotechnology - September 24, 2023 Category: Biotechnology Authors: Ofelya Baghdasaryan Shahid Khan Jung-Chen Lin Jared Lee-Kin Chung-Yao Hsu Che-Ming Jack Hu Cheemeng Tan Source Type: research
Synthetic control of living cells by intracellular polymerization
Trends Biotechnol. 2023 Sep 22:S0167-7799(23)00240-8. doi: 10.1016/j.tibtech.2023.08.006. Online ahead of print.ABSTRACTAn emerging cellular engineering method creates synthetic polymer matrices inside cells. By contrast with classical genetic, enzymatic, or radioactive techniques, this materials-based approach introduces non-natural polymers inside cells, thus modifying cellular states and functionalities. Here, we cover various materials and chemistries that have been exploited to create intracellular polymer matrices. In addition, we discuss emergent cellular properties due to the intracellular polymerization, including...
Source: Trends in Biotechnology - September 24, 2023 Category: Biotechnology Authors: Ofelya Baghdasaryan Shahid Khan Jung-Chen Lin Jared Lee-Kin Chung-Yao Hsu Che-Ming Jack Hu Cheemeng Tan Source Type: research
Synthetic control of living cells by intracellular polymerization
Trends Biotechnol. 2023 Sep 22:S0167-7799(23)00240-8. doi: 10.1016/j.tibtech.2023.08.006. Online ahead of print.ABSTRACTAn emerging cellular engineering method creates synthetic polymer matrices inside cells. By contrast with classical genetic, enzymatic, or radioactive techniques, this materials-based approach introduces non-natural polymers inside cells, thus modifying cellular states and functionalities. Here, we cover various materials and chemistries that have been exploited to create intracellular polymer matrices. In addition, we discuss emergent cellular properties due to the intracellular polymerization, including...
Source: Trends in Biotechnology - September 24, 2023 Category: Biotechnology Authors: Ofelya Baghdasaryan Shahid Khan Jung-Chen Lin Jared Lee-Kin Chung-Yao Hsu Che-Ming Jack Hu Cheemeng Tan Source Type: research
Synthetic control of living cells by intracellular polymerization
Trends Biotechnol. 2023 Sep 22:S0167-7799(23)00240-8. doi: 10.1016/j.tibtech.2023.08.006. Online ahead of print.ABSTRACTAn emerging cellular engineering method creates synthetic polymer matrices inside cells. By contrast with classical genetic, enzymatic, or radioactive techniques, this materials-based approach introduces non-natural polymers inside cells, thus modifying cellular states and functionalities. Here, we cover various materials and chemistries that have been exploited to create intracellular polymer matrices. In addition, we discuss emergent cellular properties due to the intracellular polymerization, including...
Source: Trends in Biotechnology - September 24, 2023 Category: Biotechnology Authors: Ofelya Baghdasaryan Shahid Khan Jung-Chen Lin Jared Lee-Kin Chung-Yao Hsu Che-Ming Jack Hu Cheemeng Tan Source Type: research
Chimeric antigen receptor therapy meets mRNA technology
Trends Biotechnol. 2023 Sep 21:S0167-7799(23)00239-1. doi: 10.1016/j.tibtech.2023.08.005. Online ahead of print.ABSTRACTGenetically engineered immune cells expressing chimeric antigen receptors (CARs) have emerged as a new game changer in cancer immunotherapy. The utility of CAR T cell therapy against hematological malignancies has been validated in clinical practice. Other CAR immune cells are currently under investigation to improve the potency of CAR therapy in solid tumors. As a new class of therapeutic modalities, mRNA-based therapeutics hold enormous potential beyond COVID-19 mRNA vaccines. Arming immune cells with m...
Source: Trends in Biotechnology - September 23, 2023 Category: Biotechnology Authors: Jiacai Wu Weigang Wu Boping Zhou Bin Li Source Type: research
Point-of-care detection devices for wound care and monitoring
Trends Biotechnol. 2023 Sep 9:S0167-7799(23)00257-3. doi: 10.1016/j.tibtech.2023.08.009. Online ahead of print.NO ABSTRACTPMID:37696703 | DOI:10.1016/j.tibtech.2023.08.009 (Source: Trends in Biotechnology)
Source: Trends in Biotechnology - September 11, 2023 Category: Biotechnology Authors: Shu-Wei Huang Yu-Feng Wu Tanvir Ahmed Shin-Chen Pan Chao-Min Cheng Source Type: research
Point-of-care detection devices for wound care and monitoring
Trends Biotechnol. 2023 Sep 9:S0167-7799(23)00257-3. doi: 10.1016/j.tibtech.2023.08.009. Online ahead of print.NO ABSTRACTPMID:37696703 | DOI:10.1016/j.tibtech.2023.08.009 (Source: Trends in Biotechnology)
Source: Trends in Biotechnology - September 11, 2023 Category: Biotechnology Authors: Shu-Wei Huang Yu-Feng Wu Tanvir Ahmed Shin-Chen Pan Chao-Min Cheng Source Type: research
Point-of-care detection devices for wound care and monitoring
Trends Biotechnol. 2023 Sep 9:S0167-7799(23)00257-3. doi: 10.1016/j.tibtech.2023.08.009. Online ahead of print.NO ABSTRACTPMID:37696703 | DOI:10.1016/j.tibtech.2023.08.009 (Source: Trends in Biotechnology)
Source: Trends in Biotechnology - September 11, 2023 Category: Biotechnology Authors: Shu-Wei Huang Yu-Feng Wu Tanvir Ahmed Shin-Chen Pan Chao-Min Cheng Source Type: research
Point-of-care detection devices for wound care and monitoring
Trends Biotechnol. 2023 Sep 9:S0167-7799(23)00257-3. doi: 10.1016/j.tibtech.2023.08.009. Online ahead of print.NO ABSTRACTPMID:37696703 | DOI:10.1016/j.tibtech.2023.08.009 (Source: Trends in Biotechnology)
Source: Trends in Biotechnology - September 11, 2023 Category: Biotechnology Authors: Shu-Wei Huang Yu-Feng Wu Tanvir Ahmed Shin-Chen Pan Chao-Min Cheng Source Type: research
Point-of-care detection devices for wound care and monitoring
Trends Biotechnol. 2023 Sep 9:S0167-7799(23)00257-3. doi: 10.1016/j.tibtech.2023.08.009. Online ahead of print.NO ABSTRACTPMID:37696703 | DOI:10.1016/j.tibtech.2023.08.009 (Source: Trends in Biotechnology)
Source: Trends in Biotechnology - September 11, 2023 Category: Biotechnology Authors: Shu-Wei Huang Yu-Feng Wu Tanvir Ahmed Shin-Chen Pan Chao-Min Cheng Source Type: research
Point-of-care detection devices for wound care and monitoring
Trends Biotechnol. 2023 Sep 9:S0167-7799(23)00257-3. doi: 10.1016/j.tibtech.2023.08.009. Online ahead of print.NO ABSTRACTPMID:37696703 | DOI:10.1016/j.tibtech.2023.08.009 (Source: Trends in Biotechnology)
Source: Trends in Biotechnology - September 11, 2023 Category: Biotechnology Authors: Shu-Wei Huang Yu-Feng Wu Tanvir Ahmed Shin-Chen Pan Chao-Min Cheng Source Type: research
Point-of-care detection devices for wound care and monitoring
Trends Biotechnol. 2023 Sep 9:S0167-7799(23)00257-3. doi: 10.1016/j.tibtech.2023.08.009. Online ahead of print.NO ABSTRACTPMID:37696703 | DOI:10.1016/j.tibtech.2023.08.009 (Source: Trends in Biotechnology)
Source: Trends in Biotechnology - September 11, 2023 Category: Biotechnology Authors: Shu-Wei Huang Yu-Feng Wu Tanvir Ahmed Shin-Chen Pan Chao-Min Cheng Source Type: research
Point-of-care detection devices for wound care and monitoring
Trends Biotechnol. 2023 Sep 9:S0167-7799(23)00257-3. doi: 10.1016/j.tibtech.2023.08.009. Online ahead of print.NO ABSTRACTPMID:37696703 | DOI:10.1016/j.tibtech.2023.08.009 (Source: Trends in Biotechnology)
Source: Trends in Biotechnology - September 11, 2023 Category: Biotechnology Authors: Shu-Wei Huang Yu-Feng Wu Tanvir Ahmed Shin-Chen Pan Chao-Min Cheng Source Type: research
Point-of-care detection devices for wound care and monitoring
Trends Biotechnol. 2023 Sep 9:S0167-7799(23)00257-3. doi: 10.1016/j.tibtech.2023.08.009. Online ahead of print.NO ABSTRACTPMID:37696703 | DOI:10.1016/j.tibtech.2023.08.009 (Source: Trends in Biotechnology)
Source: Trends in Biotechnology - September 11, 2023 Category: Biotechnology Authors: Shu-Wei Huang Yu-Feng Wu Tanvir Ahmed Shin-Chen Pan Chao-Min Cheng Source Type: research
