Cardiac multiscale bioimaging: from nano- through micro- to mesoscales

Trends Biotechnol. 2023 Oct 6:S0167-7799(23)00241-X. doi: 10.1016/j.tibtech.2023.08.007. Online ahead of print.ABSTRACTCardiac multiscale bioimaging is an emerging field that aims to provide a comprehensive understanding of the heart and its functions at various levels, from the molecular to the entire organ. It combines both physiologically and clinically relevant dimensions: from nano- and micrometer resolution imaging based on vibrational spectroscopy and high-resolution microscopy to assess molecular processes in cardiac cells and myocardial tissue, to mesoscale structural investigations to improve the understanding of cardiac (patho)physiology. Tailored super-resolution deep microscopy with advanced proteomic methods and hands-on experience are thus strategically combined to improve the quality of cardiovascular research and support future medical decision-making by gaining additional biomolecular information for translational and diagnostic applications.PMID:37806897 | DOI:10.1016/j.tibtech.2023.08.007
Source: Trends in Biotechnology - Category: Biotechnology Authors: Source Type: research