Transfusion Medicine and Hemotherapy Transfusion Medicine and Hemotherapy RSS feedThis is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.

The Effect of Sex-Mismatched Red Blood Cell Transfusion on Endothelial Cell Activation in Critically Ill Patients
Discussion: Transfusion of a single sex-mismatched RBC unit was associated with higher syndecan-1 and sTM levels compared to transfusion of sex-matched RBC unit. These findings may suggest that sex-mismatched RBC transfusion is associated with endothelial activation.Transfus Med Hemother (Source: Transfusion Medicine and Hemotherapy)
Source: Transfusion Medicine and Hemotherapy - November 24, 2021 Category: Hematology Source Type: research

The Impact of COVID-19 on Blood Transfusion Services: A Systematic Review and Meta-Analysis
Conclusion: Blood centres should focus more on launching initiatives and policies that would increase their countries ’ blood supply as the virus has no direct threat to blood safety.Transfus Med Hemother (Source: Transfusion Medicine and Hemotherapy)
Source: Transfusion Medicine and Hemotherapy - November 16, 2021 Category: Hematology Source Type: research

Profiling and Bioinformatics Analysis Revealing Differential Circular RNA Expression about Storage Lesion Regulatory in Stored Red Blood Cells
Conclusions: Through investigation in circRNAs profile and circRNA-miRNA-mRNA interactions, this study provides insights on stored RBC circRNA expression changes, which closely relate to the storage lesion of RBCs and their physiological functions.Transfus Med Hemother (Source: Transfusion Medicine and Hemotherapy)
Source: Transfusion Medicine and Hemotherapy - November 15, 2021 Category: Hematology Source Type: research

Emergency Use of Convalescent Plasma: Perception of the Regulatory Framework from a Clinical Perspective
The pandemic spread of an infectious disease poses a plethora of challenges to society, clinicians, health care providers and regulating authorities. In order to mount a rapid response and to provide hope in a potentially catastrophic situation as the current COVID-19 pandemic, emergency plans, regulations and funding strategies have to be developed on regional, national and international levels. The speed needed to establish rapid response programs is challenged by the dynamics of the spread of the disease, the concurrent and competing development of different and potentially more effective treatment options, and not the ...
Source: Transfusion Medicine and Hemotherapy - November 15, 2021 Category: Hematology Source Type: research

Mortality in Critically Ill Patients Does Not Differ according to Transfusion Strategy
Transfus Med Hemother (Source: Transfusion Medicine and Hemotherapy)
Source: Transfusion Medicine and Hemotherapy - November 12, 2021 Category: Hematology Source Type: research

The Evolution of Blood Product Use in Trauma Resuscitation: Change Has Come
Transfus Med Hemother (Source: Transfusion Medicine and Hemotherapy)
Source: Transfusion Medicine and Hemotherapy - November 2, 2021 Category: Hematology Source Type: research

Emergency Blood Transfusion for Trauma and Perioperative Resuscitation: Standard of Care
Uncontrolled and massive bleeding with derangement of coagulation is a major challenge in the management of both surgical and seriously injured patients. The underlying mechanism of trauma-induced or -associated coagulopathy is tissue injury in the presence of shock and acidosis provoking endothelial damage, activation of inflammation, and coagulation disbalancing. Furthermore, the combination of ongoing blood loss and consumption of blood components that are essential for effective coagulation worsens uncontrolled hemorrhage. Additionally, therapeutic actions, such as resuscitation with replacement fluids or allogeneic bl...
Source: Transfusion Medicine and Hemotherapy - October 29, 2021 Category: Hematology Source Type: research

Recent Developments in Emergency Blood Transfusion
Transfus Med Hemother (Source: Transfusion Medicine and Hemotherapy)
Source: Transfusion Medicine and Hemotherapy - October 28, 2021 Category: Hematology Source Type: research

Prehospital Whole Blood Transfusion Programs in Norway
Conclusion: HEMS services and blood banks report favorable experiences in the implementation and utilization of LTOWB. Prehospital balanced blood transfusion using whole blood is feasible in Norway.Transfus Med Hemother (Source: Transfusion Medicine and Hemotherapy)
Source: Transfusion Medicine and Hemotherapy - October 22, 2021 Category: Hematology Source Type: research

Blood Product Supply for a Helicopter Emergency Medical Service
Conclusions: Supplying HEMS with RBCs and plasma is feasible. Helicopter transport has no negative impact on blood product quality. The logistic challenges require close collaboration between the HEMS team and the blood transfusion service.Transfus Med Hemother (Source: Transfusion Medicine and Hemotherapy)
Source: Transfusion Medicine and Hemotherapy - October 19, 2021 Category: Hematology Source Type: research

Prehospital Plasma Transfusion: What Does the Literature Show?
Background: Early initiation of blood products transfusion after injury has been associated with improved patient outcomes following traumatic injury. The ability to transfuse patients ’ plasma in the prehospital setting provides a prime opportunity to begin resuscitation with blood products earlier and with a more balanced plasma:RBC ratio than what has traditionally been done. Published studies on the use of prehospital plasma show a complex relationship between its use and im proved survival.Summary: Examination of the literature shows that there may be a mortality benefit from the use of prehospital plasma, but that ...
Source: Transfusion Medicine and Hemotherapy - October 14, 2021 Category: Hematology Source Type: research

10 Years of Experience with the First Thawed Plasma Bank in Germany
Background: Plasma is stored at –30°C, which requires thawing before transfusion, causing a time delay between ordering and issuing of at least 30 min. In case of bleeding emergencies, guidelines strongly recommend a 2:1 transfusion ratio of RBCs and plasma. In addition, each minute delay in issuing of blood products in bleedin g emergencies increases the mortality risk. To provide plasma in time in bleeding emergencies, a thawed plasma bank was introduced in 2011.Summary: The thawed plasma bank of University Medicine Greifswald has provided 18,924 thawed stored plasma units between 2011 and 2020. The workflow in the la...
Source: Transfusion Medicine and Hemotherapy - October 8, 2021 Category: Hematology Source Type: research

Low-Titer Group O Whole-Blood Resuscitation in the Prehospital Setting in Israel: Review of the First 2.5 Years ’ Experience
Conclusion: Appropriate administration of LTOWB has improved over time in IDF-CSAR. Using LTOWB is feasible and simpler than administering packed red blood cells and plasma concurrently. Further efforts are needed to introduce LTOWB in other prehospital and in-hospital scenarios, with an increase in the maximum antibody titer threshold, to meet the expected increase in demand.Transfus Med Hemother (Source: Transfusion Medicine and Hemotherapy)
Source: Transfusion Medicine and Hemotherapy - October 6, 2021 Category: Hematology Source Type: research

News
Transfus Med Hemother 2021;48:319 –320 (Source: Transfusion Medicine and Hemotherapy)
Source: Transfusion Medicine and Hemotherapy - October 1, 2021 Category: Hematology Source Type: research

«Zero Bleeds» – realistisches Behandlungsziel bei Hämophilie A
Transfus Med Hemother 2021;48:316 –318 (Source: Transfusion Medicine and Hemotherapy)
Source: Transfusion Medicine and Hemotherapy - October 1, 2021 Category: Hematology Source Type: research